The Experts below are selected from a list of 144 Experts worldwide ranked by ideXlab platform
Afework Mulugeta - One of the best experts on this subject based on the ideXlab platform.
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Effect of pregnancy induced hypertension on adverse perinatal outcomes in Tigray regional state, Ethiopia: a prospective cohort study
BMC Pregnancy and Childbirth, 2019Co-Authors: Abadi Kidanemariam Berhe, Abiodun O. Ilesanmi, Christopher O. Aimakhu, Afework MulugetaAbstract:Background The prevalence of pregnancy-induced hypertension in Ethiopia ranges from 2.2 to 18.3%. However, so far little is known about the adverse perinatal outcomes of pregnancy-induced hypertension in Tigray regional state, Ethiopia. Therefore, the objective of this study was to assess the effect of pregnancy-induced hypertension on adverse perinatal outcomes in Tigray Regional State, Ethiopia. Methods a prospective cohort study was conducted on a total sample of 782 pregnant women attending antenatal care in hospitals of Tigray regional state, Ethiopia. Pregnant mothers diagnosed with PIH during the data collection period in the selected hospitals were included as exposed group and normotensive women were also enrolled as a control group. This study addresses women diagnosed with preeclampsia, eclampsia and gestational hypertension between 28 and 35 weeks of gestation. Data were collected using an interviewer-administered questionnaire and review of their medical records from February 2018, to February 2019. The adverse perinatal outcome event includes low Birth Weight, Birth asphyxia, small for gestational age, preterm delivery, admission to neonatal intensive care unit and perinatal death. A modified Poisson regression model with robust standard errors was used to analyze relative risk. Results In this study, the overall incidence of adverse perinatal outcome was higher among women with pregnancy-induced hypertension than normotensive women (66.4% vs 22.2%). After adjusted for confounders women with pregnancy-induced hypertension were born babies with a higher risk of low Birth Weight (adjusted RR (95%CI) = 5.1(3.4,7.8)), Birth asphyxia (aRR = 2.6(1.9,3.8)), small for gestational age (aRR = 3.3(2.3,4.6)), preterm delivery (aRR = 5.2(3.4,7.9)), stillBirth (aRR = 3.46(1.40,8.54)), admission to neonatal intensive care unit (aRR = 5.1(3.1,8.4)) and perinatal death (aRR = 3.6(1.8,7.4)) compared to normotensive pregnant women. Conclusions Higher incidences of adverse perinatal outcomes occurred among women pregnancy-induced hypertension in Tigray regional state, Ethiopia. Hence, health care providers should strengthen prevention, early diagnosis and prompt management of pregnancy-induced hypertension to reduce adverse perinatal outcomes of pregnancy-induced hypertension.
Antonio Boldrini - One of the best experts on this subject based on the ideXlab platform.
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correlation between placental histopathology and fetal neonatal outcome chorioamnionitis and funisitis are associated to intraventricular haemorrage and retinopathy of prematurity in preterm newborns
Gynecological Endocrinology, 2011Co-Authors: Francesca Moscuzza, Francesca Belcari, Vincenzo Nardini, Chiara Domenici, A Cuttano, Paolo Ghirri, Adrien Bartoli, Antonio BoldriniAbstract:Introduction. Placental anatomopathologic lesions are usually associated with pregnancy complications and neonatal impaired outcome.Patients and methods. We included in our study 122 patients with gestational age of 26–35 weeks. From the analysis of three pathological aspects (chorioamnionitis, funisitis and chronic hypoxia), a score was assigned to each lesion depending on the severity of the alteration, to establish a correlation with an impaired neonatal outcome in preterm newborns.Results. We found a correlation between chronic hypoxia and preeclampsia, intrauterine growth restriction and/or small-for-gestational age status at Birth. Our results also showed the strong association of fetal placental inflammatory status (chorioamnionitis and funisitis) with premature rupture of membranes, very low Birth Weight, Birth at/before 32 gestational weeks, late-onset sepsis, patent duct arteriosus, intraventricular haemorrhage (IVH) and retinopathy of prematurity (ROP).Conclusions. We confirm that placental les...
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Correlation between placental histopathology and fetal/neonatal outcome: chorioamnionitis and funisitis are associated to intraventricular haemorrage and retinopathy of prematurity in preterm newborns
Gynecological Endocrinology, 2010Co-Authors: Francesca Moscuzza, Francesca Belcari, Chiara Domenici, A Cuttano, Paolo Ghirri, Nardini, Adrien Bartoli, Antonio BoldriniAbstract:Introduction. Placental anatomopathologic lesions are usually associated with pregnancy complications and neonatal impaired outcome.Patients and methods. We included in our study 122 patients with gestational age of 26–35 weeks. From the analysis of three pathological aspects (chorioamnionitis, funisitis and chronic hypoxia), a score was assigned to each lesion depending on the severity of the alteration, to establish a correlation with an impaired neonatal outcome in preterm newborns.Results. We found a correlation between chronic hypoxia and preeclampsia, intrauterine growth restriction and/or small-for-gestational age status at Birth. Our results also showed the strong association of fetal placental inflammatory status (chorioamnionitis and funisitis) with premature rupture of membranes, very low Birth Weight, Birth at/before 32 gestational weeks, late-onset sepsis, patent duct arteriosus, intraventricular haemorrhage (IVH) and retinopathy of prematurity (ROP).Conclusions. We confirm that placental les...
Abadi Kidanemariam Berhe - One of the best experts on this subject based on the ideXlab platform.
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Effect of pregnancy induced hypertension on adverse perinatal outcomes in Tigray regional state, Ethiopia: a prospective cohort study
BMC Pregnancy and Childbirth, 2019Co-Authors: Abadi Kidanemariam Berhe, Abiodun O. Ilesanmi, Christopher O. Aimakhu, Afework MulugetaAbstract:Background The prevalence of pregnancy-induced hypertension in Ethiopia ranges from 2.2 to 18.3%. However, so far little is known about the adverse perinatal outcomes of pregnancy-induced hypertension in Tigray regional state, Ethiopia. Therefore, the objective of this study was to assess the effect of pregnancy-induced hypertension on adverse perinatal outcomes in Tigray Regional State, Ethiopia. Methods a prospective cohort study was conducted on a total sample of 782 pregnant women attending antenatal care in hospitals of Tigray regional state, Ethiopia. Pregnant mothers diagnosed with PIH during the data collection period in the selected hospitals were included as exposed group and normotensive women were also enrolled as a control group. This study addresses women diagnosed with preeclampsia, eclampsia and gestational hypertension between 28 and 35 weeks of gestation. Data were collected using an interviewer-administered questionnaire and review of their medical records from February 2018, to February 2019. The adverse perinatal outcome event includes low Birth Weight, Birth asphyxia, small for gestational age, preterm delivery, admission to neonatal intensive care unit and perinatal death. A modified Poisson regression model with robust standard errors was used to analyze relative risk. Results In this study, the overall incidence of adverse perinatal outcome was higher among women with pregnancy-induced hypertension than normotensive women (66.4% vs 22.2%). After adjusted for confounders women with pregnancy-induced hypertension were born babies with a higher risk of low Birth Weight (adjusted RR (95%CI) = 5.1(3.4,7.8)), Birth asphyxia (aRR = 2.6(1.9,3.8)), small for gestational age (aRR = 3.3(2.3,4.6)), preterm delivery (aRR = 5.2(3.4,7.9)), stillBirth (aRR = 3.46(1.40,8.54)), admission to neonatal intensive care unit (aRR = 5.1(3.1,8.4)) and perinatal death (aRR = 3.6(1.8,7.4)) compared to normotensive pregnant women. Conclusions Higher incidences of adverse perinatal outcomes occurred among women pregnancy-induced hypertension in Tigray regional state, Ethiopia. Hence, health care providers should strengthen prevention, early diagnosis and prompt management of pregnancy-induced hypertension to reduce adverse perinatal outcomes of pregnancy-induced hypertension.
Torsten Tuvemo - One of the best experts on this subject based on the ideXlab platform.
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Intellectual performance in young adult males born small for gestational age.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 2020Co-Authors: Maria Lundgren, Sven Cnattingius, Björn Jonsson, Torsten TuvemoAbstract:Children born small for gestational age (SGA) have increased risk of neurological dysfunction. The aim of this study was to analyze intellectual performance in early adult age in children born SGA, and especially the effect of catch up growth in height. Data on gestational age and Birth size were taken from the Swedish Birth Register and data on adult height and intellectual performance from the Swedish Conscript Register. Low Birth Weight, Birth length and head circumference increased the risk of subnormal intellectual and psychological performance in males born SGA. Very low gestational age also increased the risk. However, the most important predictor was the absence of catch up growth to a height above -2 SDS in individuals born SGA.
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Intellectual performance in young adult males born small for gestational age.
Growth Hormone & Igf Research, 2004Co-Authors: Maria Lundgren, Sven Cnattingius, Björn Jonsson, Torsten TuvemoAbstract:Abstract Children born small for gestational age (SGA) have increased risk of neurological dysfunction. The aim of this study was to analyze intellectual performance in early adult age in children born SGA, and especially the effect of catch up growth in height. Methods: Data on gestational age and Birth size were taken from the Swedish Birth Register and data on adult height and intellectual performance from the Swedish Conscript Register. Results: Low Birth Weight, Birth length and head circumference increased the risk of subnormal intellectual and psychological performance in males born SGA. Very low gestational age also increased the risk. However, the most important predictor was the absence of catch up growth to a height above −2 SDS in individuals born SGA.
K. Sommerfelt - One of the best experts on this subject based on the ideXlab platform.
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Long-term outcome for non-handicapped low Birth Weight infants – is the fog clearing?
European Journal of Pediatrics, 1998Co-Authors: K. SommerfeltAbstract:The frequency of cerebral palsy increases with decreasing gestational age affecting approximately 7% of survivors with Birth Weights less than 1500 g (very low Birth Weight, VLBW) [7]. In addition, low Birth Weight (Birth Weight less than 2500 g, LBW) and VLBW children without cerebral palsy or other major neurohandicaps have an increased frequency of “new morbidities” including learning disabilities, behavioural problems, lower mean IQ, and motor clumsiness compared to normal Birth Weight peers [15, 16, 20]. However, understanding is still lacking regarding the nature and frequency of such problems, predisposing risk factors, and the relationship of such problems with parental factors, including socio-economic status. A fundamental concept for understanding the large and often confusing literature on LBW and later neurobehavioral development is that LBW may have many different aetiologies, with varying relative frequency in different populations, which probably have different degrees of associated risk for impairment of later development [12, 26].
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Long-term outcome for non-handicapped low Birth Weight infants – is the fog clearing?
European Journal of Pediatrics, 1998Co-Authors: K. SommerfeltAbstract:The frequency of cerebral palsy increases with decreasing gestational age affecting approximately 7% of survivors with Birth Weights less than 1500 g (very low Birth Weight, VLBW) [7]. In addition, low Birth Weight (Birth Weight less than 2500 g, LBW) and VLBW children without cerebral palsy or other major neurohandicaps have an increased frequency of “new morbidities” including learning disabilities, behavioural problems, lower mean IQ, and motor clumsiness compared to normal Birth Weight peers [15, 16, 20]. However, understanding is still lacking regarding the nature and frequency of such problems, predisposing risk factors, and the relationship of such problems with parental factors, including socio-economic status.
