Low Calorie Diet

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Y Takamura - One of the best experts on this subject based on the ideXlab platform.

  • Very-Low-Calorie-Diet therapy in severe obesity.
    The American Journal of Clinical Nutrition, 1992
    Co-Authors: R Yamamoto, Shuji Inoue, M Saito, M Okamoto, A Okamura, Y Takamura
    Abstract:

    This study investigated the effects of very-Low-Calorie-Diet (VLCD) therapy on body weight, plasma glucose, and lipid metabolism in severely obese patients. Ninety-one patients were subjected to VLCD therapy for 4-24 wk. Reduction of body weight was remarkable during the first 4 wk, then leveled off despite continuous treatment. Fasting plasma glucose, triglyceride, and 75-g oral glucose-tolerance test showed a significant improvement. Total cholesterol fell in the early stages but then increased more than the pretreatment level during VLCD. VLCD therapy is useful for the treatment of severe obesity.

E Leutenegger - One of the best experts on this subject based on the ideXlab platform.

  • long term maintenance of weight loss after a very Low Calorie Diet a randomized blinded trial of the efficacy and tolerability of sibutramine
    The American Journal of Medicine, 1999
    Co-Authors: Marian Apfelbaum, Corinne Hanotin, Florence Thomas, Philippe Vague, O Ziegler, E Leutenegger
    Abstract:

    Abstract BACKGROUND: Very-Low-Calorie Diets are a well established method to achieve substantial short-term weight loss in obese patients, but long-term maintenance of the weight loss is very disappointing. A combined very-Low-Calorie Diet and pharmacologic approach could be an effective means of prolonging its benefits. PATIENTS AND METHODS: Eligible patients had a body-mass index greater than 30 kg/m 2 ; those who lost 6 kg or more during a 4-week treatment with a very-Low-Calorie Diet were randomly assigned to 1 year of treatment with sibutramine (10 mg) or identical placebo. RESULTS: In an intention-to-treat analysis, mean (±SD) absolute weight change at 1 year (or study endpoint) was −5.2 (±7.5) kg in the 81 patients in the sibutramine group and +0.5 (±5.7) kg in the 78 patients in the placebo group ( P = 0.004). When compared with their weight at study entry (before the very-Low-Calorie Diet), 86% of patients in the sibutramine group had lost at least 5% of their weight, compared with only 55% of those in the placebo group ( P P CONCLUSION: FolLowing a very-Low-Calorie Diet, sibutramine is effective in maintaining and improving weight loss for up to 1 year.

Leila Azadbakht - One of the best experts on this subject based on the ideXlab platform.

  • The effect of Low Calorie Diet on adiponectin concentration: a systematic review and meta-analysis.
    Hormone and Metabolic Research, 2015
    Co-Authors: Amin Salehi-abargouei, Vajihe Izadi, Leila Azadbakht
    Abstract:

    Adiponectin secreted from adipose tissue is proposed to be inversely related to the body fat mass. However, the magnitude of the effect of Low Calorie Diet on adiponectin concentrations remains unknown. The present study was aimed to conduct a systematic review and meta-analysis on clinical trials that access the effect of Low Calorie Diet on adiponectin concentration. We searched PubMed, SCOPUS, ISI web of science, and Google scholar for RCTs until January 2015. Totally, 13 trials were found, which examined the effect of Low Calorie Diet on adiponectin concentration compared control group without Low Calorie Diet. Our meta-analysis showed that weight loss Diet can substantially increase the adiponectin concentration in overall (Hedges’ g=0.34, 95% CI:0.17–0.50, p 16 weeks (Hedges’ g=0.30, 95% CI: 0.11–0.48, p=0.002). Weight loss Diet beneficially affects blood adiponectin concentrations. More clinical trials are recommended to clear this effect among different genders and nationalities, and assess the magnitude of the effect based on changes in fat mass.

  • The effect of Low Calorie Diet on adiponectin concentration: a systematic review and meta-analysis.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2015
    Co-Authors: Amin Salehi-abargouei, Vajihe Izadi, Leila Azadbakht
    Abstract:

    Adiponectin secreted from adipose tissue is proposed to be inversely related to the body fat mass. However, the magnitude of the effect of Low Calorie Diet on adiponectin concentrations remains unknown. The present study was aimed to conduct a systematic review and meta-analysis on clinical trials that access the effect of Low Calorie Diet on adiponectin concentration. We searched PubMed, SCOPUS, ISI web of science, and Google scholar for RCTs until January 2015. Totally, 13 trials were found, which examined the effect of Low Calorie Diet on adiponectin concentration compared control group without Low Calorie Diet.Our meta-analysis showed that weight loss Diet can substantially increase the adiponectin concentration in overall (Hedges' g=0.34, 95% CI:0.17-0.50, p

Saeed Asefzadeh - One of the best experts on this subject based on the ideXlab platform.

Tetsuya Oshima - One of the best experts on this subject based on the ideXlab platform.

  • a Low Calorie Diet improves endothelium dependent vasodilation in obese patients with essential hypertension
    American Journal of Hypertension, 2002
    Co-Authors: Shota Sasaki, Yukihito Higashi, Hideo Matsuura, Keigo Nakagawa, Masashi Kimura, Kensuke Noma, Satoshi Sasaki, Keiko Hara, Chikara Goto, Tetsuya Oshima
    Abstract:

    Abstract Background Both obesity and hypertension are associated with endothelial dysfunction. The purpose of this study was to investigate the effects of a Low-Calorie Diet on endothelial function in obese patients with essential hypertension. Methods We measured forearm blood fLow (FBF) during intra-arterial infusion of acetylcholine (ACh; 7.5, 15, 30 μg/min), an index of endothelium-dependent vasodilation, and isosorbide dinitrate (ISDN; 0.75, 1.5, 3.0 μg/min), an index of endothelium-independent vasodilation, in obese patients with essential hypertension before and after 2 weeks on a Low-Calorie Diet (800 kcal/d). The study included 11 obese hypertensive Japanese patients (mean body mass index, 30.8 ± 3.6 kg/m2). Fifteen healthy Japanese normotensive individuals were recruited as a control group. Results In obese patients with hypertension, the response of FBF to ACh was attenuated compared to healthy individuals (P l -arginine (8 μmol/min), a nitric oxide synthase inhibitor, decreased the enhanced ACh-induced blood fLow response induced by caloric restriction. Conclusions The present findings suggest that the caloric restriction improves endothelial-dependent vasodilation through an increased release of nitric oxide in obese hypertensive patients.

  • A Low-Calorie Diet Improves Endothelium-Dependent Vasodilation in Obese Patients with Essential Hypertension
    Hypertension, 2000
    Co-Authors: Shota Sasaki, Yukihito Higashi, Ryoji Ozono, Hideo Matsuura, Goro Kajiyama, Tetsuya Oshima
    Abstract:

    P179 Objective: This study investigated the effects of a Low-Calorie Diet on endothelial function in obese patients with essential hypertension. Methods: We measured forearm blood fLow during intraarterial infusion of acetylcholine (7.5, 15, 30 μg/min, an index of endothelium-dependent vasodilation) and isosorbide dinitrate (0.75, 1.5, 3.0 μg/min, an index of endothelium-independent vasodilation) in obese patients with essential hypertension before and after 2-weeks of the Low-Calorie Diet (800 Kcal/d). The study included 11 obese hypertensive Japanese patients (mean body mass index: 30.8 ± 3.6 kg/m2). Fifteen healthy Japanese normotensive individuals were recruited as a control group. Results: In obese patients with hypertension, the response of forearm blood fLow to acetylcholine was attenuated compared to healthy individuals (P

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