The Experts below are selected from a list of 279 Experts worldwide ranked by ideXlab platform
Michael J Larson - One of the best experts on this subject based on the ideXlab platform.
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A direct comparison between ERP and fMRI measurements of Food-related inhibitory control: Implications for BMI status and dietary intake
NeuroImage, 2017Co-Authors: Kaylie A Carbine, James D Lecheminant, Kara M. Duraccio, C. Brock Kirwan, Nathan M. Muncy, Michael J LarsonAbstract:Abstract Obesity and maintaining a healthy diet have important implications for physical and mental health. One factor that may influence diet and obesity is inhibitory control. We tested how N2 and P3 amplitude, event-related potential (ERP) components that reflect inhibitory control, and functional magnetic resonance imaging (fMRI) activity in brain regions associated with inhibitory control differed toward high- and Low-Calorie Food stimuli across BMI status. We also assessed the relationship between neural indices of Food-related inhibitory control and laboratory and daily Food intake. Fifty-four individuals (17 normal-weight; 18 overweight; 19 individuals with obesity) completed two Food-based go/no-go tasks (one with high- and one with Low-Calorie Foods as no-go stimuli), once during ERP data acquisition and once during fMRI data acquisition. After testing, participants were presented with an ad libitum weighed Food buffet. Participants also recorded their Food intake using the Automated Self-Administered 24-hour Dietary Recall (ASA24) system across four days. Individuals recruited more inhibitory control when withholding responses towards high-compared to Low-Calorie Foods, although this effect was more consistent for N2 than P3 or fMRI assessments. BMI status did not influence Food-related inhibitory control. A larger inhibitory response as measured by N2 amplitude was related to increased ASA24 Food intake; P3 amplitude and fMRI region of interest activity did not predict ASA24 intake; neither method predicted Food intake from the buffet. ERP and fMRI measurements show similar neural responses to Food, although N2 amplitude may be somewhat more sensitive in detecting differences between Food types and predicting self-reports of Food intake.
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testing Food related inhibitory control to high and Low Calorie Food stimuli electrophysiological responses to high Calorie Food stimuli predict Calorie and carbohydrate intake
Psychophysiology, 2017Co-Authors: Kaylie A Carbine, Edward Christensen, James D Lecheminant, Bruce W Bailey, Larry A Tucker, Michael J LarsonAbstract:Maintaining a healthy diet has important implications for physical and mental health. One factor that may influence diet and Food consumption is inhibitory control—the ability to withhold a dominant response in order to correctly respond to environmental demands. We examined how N2 amplitude, an ERP that reflects inhibitory control processes, differed toward high- and Low-Calorie Food stimuli and related to Food intake. A total of 159 participants (81 female; M age = 23.5 years; SD = 7.6) completed two Food-based go/no-go tasks (one with high-Calorie and one with Low-Calorie Food pictures as no-go stimuli) while N2 amplitude was recorded. Participants recorded Food intake using the Automated Self-Administered 24-hour Dietary Recall system. Inhibiting responses toward high-Calorie stimuli elicited a larger (i.e., more negative) no-go N2 amplitude; inhibiting responses toward Low-Calorie stimuli elicited a smaller no-go N2 amplitude. Participants were more accurate during the high-Calorie than Low-Calorie task, but took longer to respond on go trials toward high-Calorie rather than Low-Calorie stimuli. When controlling for age, gender, and BMI, larger high-Calorie N2 difference amplitude predicted Lower caloric intake (β = 0.17); Low-Calorie N2 difference amplitude was not related to caloric intake (β = −0.03). Exploratory analyses revealed larger high-Calorie N2 difference amplitude predicted carbohydrate intake (β = 0.22), but not protein (β = 0.08) or fat (β = 0.11) intake. Results suggest that withholding responses from high-Calorie Foods requires increased recruitment of inhibitory control processes, which may be necessary to regulate Food consumption, particularly for Foods high in Calories and carbohydrates.
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Testing Food‐related inhibitory control to high‐ and Low‐Calorie Food stimuli: Electrophysiological responses to high‐Calorie Food stimuli predict Calorie and carbohydrate intake
Psychophysiology, 2017Co-Authors: Kaylie A Carbine, Edward Christensen, James D Lecheminant, Bruce W Bailey, Larry A Tucker, Michael J LarsonAbstract:Maintaining a healthy diet has important implications for physical and mental health. One factor that may influence diet and Food consumption is inhibitory control—the ability to withhold a dominant response in order to correctly respond to environmental demands. We examined how N2 amplitude, an ERP that reflects inhibitory control processes, differed toward high- and Low-Calorie Food stimuli and related to Food intake. A total of 159 participants (81 female; M age = 23.5 years; SD = 7.6) completed two Food-based go/no-go tasks (one with high-Calorie and one with Low-Calorie Food pictures as no-go stimuli) while N2 amplitude was recorded. Participants recorded Food intake using the Automated Self-Administered 24-hour Dietary Recall system. Inhibiting responses toward high-Calorie stimuli elicited a larger (i.e., more negative) no-go N2 amplitude; inhibiting responses toward Low-Calorie stimuli elicited a smaller no-go N2 amplitude. Participants were more accurate during the high-Calorie than Low-Calorie task, but took longer to respond on go trials toward high-Calorie rather than Low-Calorie stimuli. When controlling for age, gender, and BMI, larger high-Calorie N2 difference amplitude predicted Lower caloric intake (β = 0.17); Low-Calorie N2 difference amplitude was not related to caloric intake (β = −0.03). Exploratory analyses revealed larger high-Calorie N2 difference amplitude predicted carbohydrate intake (β = 0.22), but not protein (β = 0.08) or fat (β = 0.11) intake. Results suggest that withholding responses from high-Calorie Foods requires increased recruitment of inhibitory control processes, which may be necessary to regulate Food consumption, particularly for Foods high in Calories and carbohydrates.
Yesim Erim - One of the best experts on this subject based on the ideXlab platform.
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pavlovian to instrumental transfer in anorexia nervosa a pilot study on conditioned learning and instrumental responding to Low and high Calorie Food stimuli
European Journal of Neuroscience, 2020Co-Authors: Verena Vogel, Georgios Paslakis, Elisabeth Rauh, Yesim Erim, Marie Dittrich, Stefanie Horndasch, Oliver Kratz, Gunther H Moll, Sabine SteinsloeberAbstract:Anorexia Nervosa is characterized by persistent restraint eating despite severe negative consequences and often a chronic course of the disease. Recent theoretical models suggest that abnormalities in reward processing and incentive salience of disorder-compatible stimuli as observed in addictive behaviours contribute to the development and maintenance of Anorexia Nervosa. The aim of the present study was to investigate the process of the acquisition of Food-related conditioned responses and the influence of conditioned Low-Calorie and high-Calorie Food stimuli on instrumental responding for different Foods. A Pavlovian-to-instrumental transfer paradigm and questionnaires on eating disorder psychopathology (EDE-Q, EDI-2) were administered to patients with Anorexia Nervosa (n = 39) and healthy controls (n = 41). Results indicated that patients with Anorexia Nervosa showed deficits of the acquisition of knowledge of the experimental contingencies. Nevertheless, in patients with Anorexia Nervosa and healthy controls instrumental responding for Low- and high-Calorie Food rewards was affected by stimuli conditioned to these rewards; no group differences were observed. Importantly, in Anorexia Nervosa, instrumental responding for Low-Calorie Food increased with increasing severity of eating disorder psychopathology suggesting weight-loss directed behaviour. Future studies are warranted to enhance our understanding of deficits of reward-associated learning and to replicate and extend findings with regard to the impact of conditioned stimuli on instrumental responding. At present, our findings suggest that cognitive treatment interventions might be warranted that challenge dysfunctional beliefs about weight loss.
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explicit and implicit approach vs avoidance tendencies towards high vs Low Calorie Food cues in patients with obesity and active binge eating disorder
Nutrients, 2017Co-Authors: Georgios Paslakis, Simone Kuhn, Sebastian Grunert, Yesim ErimAbstract:Patients with binge eating disorder (BED) suffer from regular Food binges with loss of control. This may be due to dysfunctional approach vs. avoidance tendencies towards Food in BED. We applied an approach-avoidance task (AAT), in which n = 24 patients with obesity and active BED (OB-BED), n = 32 patients with obesity without current BED (OB), and n = 25 healthy controls (CO) either approached (“pulled”) or avoided (“pushed”) high (HC) vs. Low Calorie (LC) Food pictures. We tested the hypothesis that OB-BED patients would show an approach bias (measured as different response times RT) towards HC Food compared to the other groups. While there was no main effect for group or direction of movement, a significant main effect for Calorie (p < 0.001; RT for HC significantly sLower than for LC) was found. Repeated measures ANOVA (rm-ANOVA) for comparison of OB-BED vs. OB vs. CO revealed a significant three-fold interaction group × direction × Calorie (p = 0.02). Against our hypothesis, the OB-BED group showed an avoidance bias for LC. In explicit ratings, OB-BED reported a significantly reduced urge to consume LC Food compared to the OB group. Similar to OB-BED, CO also showed an avoidance bias for LC. The implications of our results are discussed and future directions in this field of research are presented.
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explicit and implicit approach vs avoidance tendencies towards high vs Low Calorie Food cues in patients with anorexia nervosa and healthy controls
Appetite, 2016Co-Authors: Georgios Paslakis, Simone Kuhn, Anke Schaubschlager, Katharina Schieber, Kathrin Roder, Elisabeth Rauh, Yesim ErimAbstract:Abstract Patients with anorexia nervosa (AN) have a strong ability to limit Food intake. Thus, dysfunctional approach vs. avoidance behaviors towards Food are evident in AN. We applied an approach-avoidance task (AAT), in which n = 41 AN patients and n = 42 controls either approached (“pull”) or avoided (“push”) high (HC) vs. Low Calorie (LC) Food pictures based solely on the presented picture format (landscape vs. portrait). We tested the hypothesis that -in opposition to controls displaying an approach bias towards HC Food cues- AN patients would show an avoidance bias (measured as different response times) towards HC Food. Explicit ratings of Food cues were also performed. We found a significant interaction “group” x “direction” (p = 0.03). rm-ANOVAs performed for each of the two groups separately showed a main effect for “direction” of motion in controls (p = 0.02), but not in AN patients (p = 0.40). The two groups did not differ in their reaction times (RTs) with regard to “push” (p = 0.27). However, RTs with regard to “pull” were significantly different between the groups (p = 0.04). Controls show a clear approach bias, expressed by significantly faster RTs for “pull” compared to “push”, independent of “Calorie” content of the Food stimuli. This approach bias is absent in the group of AN patients. This is indicative of a global loss of incentive value of Food in AN. Implicit trainings as add-on to psychotherapy in AN patients are asked for.
Georgios Paslakis - One of the best experts on this subject based on the ideXlab platform.
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pavlovian to instrumental transfer in anorexia nervosa a pilot study on conditioned learning and instrumental responding to Low and high Calorie Food stimuli
European Journal of Neuroscience, 2020Co-Authors: Verena Vogel, Georgios Paslakis, Elisabeth Rauh, Yesim Erim, Marie Dittrich, Stefanie Horndasch, Oliver Kratz, Gunther H Moll, Sabine SteinsloeberAbstract:Anorexia Nervosa is characterized by persistent restraint eating despite severe negative consequences and often a chronic course of the disease. Recent theoretical models suggest that abnormalities in reward processing and incentive salience of disorder-compatible stimuli as observed in addictive behaviours contribute to the development and maintenance of Anorexia Nervosa. The aim of the present study was to investigate the process of the acquisition of Food-related conditioned responses and the influence of conditioned Low-Calorie and high-Calorie Food stimuli on instrumental responding for different Foods. A Pavlovian-to-instrumental transfer paradigm and questionnaires on eating disorder psychopathology (EDE-Q, EDI-2) were administered to patients with Anorexia Nervosa (n = 39) and healthy controls (n = 41). Results indicated that patients with Anorexia Nervosa showed deficits of the acquisition of knowledge of the experimental contingencies. Nevertheless, in patients with Anorexia Nervosa and healthy controls instrumental responding for Low- and high-Calorie Food rewards was affected by stimuli conditioned to these rewards; no group differences were observed. Importantly, in Anorexia Nervosa, instrumental responding for Low-Calorie Food increased with increasing severity of eating disorder psychopathology suggesting weight-loss directed behaviour. Future studies are warranted to enhance our understanding of deficits of reward-associated learning and to replicate and extend findings with regard to the impact of conditioned stimuli on instrumental responding. At present, our findings suggest that cognitive treatment interventions might be warranted that challenge dysfunctional beliefs about weight loss.
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explicit and implicit approach vs avoidance tendencies towards high vs Low Calorie Food cues in patients with obesity and active binge eating disorder
Nutrients, 2017Co-Authors: Georgios Paslakis, Simone Kuhn, Sebastian Grunert, Yesim ErimAbstract:Patients with binge eating disorder (BED) suffer from regular Food binges with loss of control. This may be due to dysfunctional approach vs. avoidance tendencies towards Food in BED. We applied an approach-avoidance task (AAT), in which n = 24 patients with obesity and active BED (OB-BED), n = 32 patients with obesity without current BED (OB), and n = 25 healthy controls (CO) either approached (“pulled”) or avoided (“pushed”) high (HC) vs. Low Calorie (LC) Food pictures. We tested the hypothesis that OB-BED patients would show an approach bias (measured as different response times RT) towards HC Food compared to the other groups. While there was no main effect for group or direction of movement, a significant main effect for Calorie (p < 0.001; RT for HC significantly sLower than for LC) was found. Repeated measures ANOVA (rm-ANOVA) for comparison of OB-BED vs. OB vs. CO revealed a significant three-fold interaction group × direction × Calorie (p = 0.02). Against our hypothesis, the OB-BED group showed an avoidance bias for LC. In explicit ratings, OB-BED reported a significantly reduced urge to consume LC Food compared to the OB group. Similar to OB-BED, CO also showed an avoidance bias for LC. The implications of our results are discussed and future directions in this field of research are presented.
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explicit and implicit approach vs avoidance tendencies towards high vs Low Calorie Food cues in patients with anorexia nervosa and healthy controls
Appetite, 2016Co-Authors: Georgios Paslakis, Simone Kuhn, Anke Schaubschlager, Katharina Schieber, Kathrin Roder, Elisabeth Rauh, Yesim ErimAbstract:Abstract Patients with anorexia nervosa (AN) have a strong ability to limit Food intake. Thus, dysfunctional approach vs. avoidance behaviors towards Food are evident in AN. We applied an approach-avoidance task (AAT), in which n = 41 AN patients and n = 42 controls either approached (“pull”) or avoided (“push”) high (HC) vs. Low Calorie (LC) Food pictures based solely on the presented picture format (landscape vs. portrait). We tested the hypothesis that -in opposition to controls displaying an approach bias towards HC Food cues- AN patients would show an avoidance bias (measured as different response times) towards HC Food. Explicit ratings of Food cues were also performed. We found a significant interaction “group” x “direction” (p = 0.03). rm-ANOVAs performed for each of the two groups separately showed a main effect for “direction” of motion in controls (p = 0.02), but not in AN patients (p = 0.40). The two groups did not differ in their reaction times (RTs) with regard to “push” (p = 0.27). However, RTs with regard to “pull” were significantly different between the groups (p = 0.04). Controls show a clear approach bias, expressed by significantly faster RTs for “pull” compared to “push”, independent of “Calorie” content of the Food stimuli. This approach bias is absent in the group of AN patients. This is indicative of a global loss of incentive value of Food in AN. Implicit trainings as add-on to psychotherapy in AN patients are asked for.
Kaylie A Carbine - One of the best experts on this subject based on the ideXlab platform.
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A direct comparison between ERP and fMRI measurements of Food-related inhibitory control: Implications for BMI status and dietary intake
NeuroImage, 2017Co-Authors: Kaylie A Carbine, James D Lecheminant, Kara M. Duraccio, C. Brock Kirwan, Nathan M. Muncy, Michael J LarsonAbstract:Abstract Obesity and maintaining a healthy diet have important implications for physical and mental health. One factor that may influence diet and obesity is inhibitory control. We tested how N2 and P3 amplitude, event-related potential (ERP) components that reflect inhibitory control, and functional magnetic resonance imaging (fMRI) activity in brain regions associated with inhibitory control differed toward high- and Low-Calorie Food stimuli across BMI status. We also assessed the relationship between neural indices of Food-related inhibitory control and laboratory and daily Food intake. Fifty-four individuals (17 normal-weight; 18 overweight; 19 individuals with obesity) completed two Food-based go/no-go tasks (one with high- and one with Low-Calorie Foods as no-go stimuli), once during ERP data acquisition and once during fMRI data acquisition. After testing, participants were presented with an ad libitum weighed Food buffet. Participants also recorded their Food intake using the Automated Self-Administered 24-hour Dietary Recall (ASA24) system across four days. Individuals recruited more inhibitory control when withholding responses towards high-compared to Low-Calorie Foods, although this effect was more consistent for N2 than P3 or fMRI assessments. BMI status did not influence Food-related inhibitory control. A larger inhibitory response as measured by N2 amplitude was related to increased ASA24 Food intake; P3 amplitude and fMRI region of interest activity did not predict ASA24 intake; neither method predicted Food intake from the buffet. ERP and fMRI measurements show similar neural responses to Food, although N2 amplitude may be somewhat more sensitive in detecting differences between Food types and predicting self-reports of Food intake.
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testing Food related inhibitory control to high and Low Calorie Food stimuli electrophysiological responses to high Calorie Food stimuli predict Calorie and carbohydrate intake
Psychophysiology, 2017Co-Authors: Kaylie A Carbine, Edward Christensen, James D Lecheminant, Bruce W Bailey, Larry A Tucker, Michael J LarsonAbstract:Maintaining a healthy diet has important implications for physical and mental health. One factor that may influence diet and Food consumption is inhibitory control—the ability to withhold a dominant response in order to correctly respond to environmental demands. We examined how N2 amplitude, an ERP that reflects inhibitory control processes, differed toward high- and Low-Calorie Food stimuli and related to Food intake. A total of 159 participants (81 female; M age = 23.5 years; SD = 7.6) completed two Food-based go/no-go tasks (one with high-Calorie and one with Low-Calorie Food pictures as no-go stimuli) while N2 amplitude was recorded. Participants recorded Food intake using the Automated Self-Administered 24-hour Dietary Recall system. Inhibiting responses toward high-Calorie stimuli elicited a larger (i.e., more negative) no-go N2 amplitude; inhibiting responses toward Low-Calorie stimuli elicited a smaller no-go N2 amplitude. Participants were more accurate during the high-Calorie than Low-Calorie task, but took longer to respond on go trials toward high-Calorie rather than Low-Calorie stimuli. When controlling for age, gender, and BMI, larger high-Calorie N2 difference amplitude predicted Lower caloric intake (β = 0.17); Low-Calorie N2 difference amplitude was not related to caloric intake (β = −0.03). Exploratory analyses revealed larger high-Calorie N2 difference amplitude predicted carbohydrate intake (β = 0.22), but not protein (β = 0.08) or fat (β = 0.11) intake. Results suggest that withholding responses from high-Calorie Foods requires increased recruitment of inhibitory control processes, which may be necessary to regulate Food consumption, particularly for Foods high in Calories and carbohydrates.
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Testing Food‐related inhibitory control to high‐ and Low‐Calorie Food stimuli: Electrophysiological responses to high‐Calorie Food stimuli predict Calorie and carbohydrate intake
Psychophysiology, 2017Co-Authors: Kaylie A Carbine, Edward Christensen, James D Lecheminant, Bruce W Bailey, Larry A Tucker, Michael J LarsonAbstract:Maintaining a healthy diet has important implications for physical and mental health. One factor that may influence diet and Food consumption is inhibitory control—the ability to withhold a dominant response in order to correctly respond to environmental demands. We examined how N2 amplitude, an ERP that reflects inhibitory control processes, differed toward high- and Low-Calorie Food stimuli and related to Food intake. A total of 159 participants (81 female; M age = 23.5 years; SD = 7.6) completed two Food-based go/no-go tasks (one with high-Calorie and one with Low-Calorie Food pictures as no-go stimuli) while N2 amplitude was recorded. Participants recorded Food intake using the Automated Self-Administered 24-hour Dietary Recall system. Inhibiting responses toward high-Calorie stimuli elicited a larger (i.e., more negative) no-go N2 amplitude; inhibiting responses toward Low-Calorie stimuli elicited a smaller no-go N2 amplitude. Participants were more accurate during the high-Calorie than Low-Calorie task, but took longer to respond on go trials toward high-Calorie rather than Low-Calorie stimuli. When controlling for age, gender, and BMI, larger high-Calorie N2 difference amplitude predicted Lower caloric intake (β = 0.17); Low-Calorie N2 difference amplitude was not related to caloric intake (β = −0.03). Exploratory analyses revealed larger high-Calorie N2 difference amplitude predicted carbohydrate intake (β = 0.22), but not protein (β = 0.08) or fat (β = 0.11) intake. Results suggest that withholding responses from high-Calorie Foods requires increased recruitment of inhibitory control processes, which may be necessary to regulate Food consumption, particularly for Foods high in Calories and carbohydrates.
Paul A M Smeets - One of the best experts on this subject based on the ideXlab platform.
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functional mri of challenging Food choices forced choice between equally liked high and Low Calorie Foods in the absence of hunger
PLOS ONE, 2015Co-Authors: Lisette Charbonnier, Laura N Van Der Laan, Max A Viergever, Paul A M SmeetsAbstract:We are continuously exposed to Food and during the day we make many Food choices. These choices play an important role in the regulation of Food intake and thereby in weight management. Therefore, it is important to obtain more insight into the mechanisms that underlie these choices. While several Food choice functional MRI (fMRI) studies have been conducted, the effect of energy content on neural responses during Food choice has, to our knowledge, not been investigated before. Our objective was to examine brain responses during Food choices between equally liked high- and Low-Calorie Foods in the absence of hunger. During a 10-min fMRI scan 19 normal weight volunteers performed a forced-choice task. Food pairs were matched on individual liking but differed in perceived and actual caloric content (high-Low). Food choice compared with non-Food choice elicited stronger unilateral activation in the left insula, superior temporal sulcus, posterior cingulate gyrus and (pre)cuneus. This suggests that the Food stimuli were more salient despite subject’s Low motivation to eat. The right superior temporal sulcus (STS) was the only region that exhibited greater activation for high versus Low Calorie Food choices between Foods matched on liking. Together with previous studies, this suggests that STS activation during Food evaluation and choice may reflect the Food’s biological relevance independent of Food preference. This novel finding warrants further research into the effects of hunger state and weight status on STS, which may provide a marker of biological relevance.
