The Experts below are selected from a list of 264 Experts worldwide ranked by ideXlab platform
Maria Fiatarone A Singh - One of the best experts on this subject based on the ideXlab platform.
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resistance training to counteract the catabolism of a Low Protein Diet in patients with chronic renal insufficiency a randomized controlled trial
Annals of Internal Medicine, 2001Co-Authors: Carmen Castaneda, Patricia L Gordon, Katherine Leigh Uhlin, Andrew S Levey, Joseph J Kehayias, Johanna T Dwyer, Roger A Fielding, Ronenn Roubenoff, Maria Fiatarone A SinghAbstract:BACKGROUND: Chronic renal insufficiency leads to muscle wasting, which may be exacerbated by Low-Protein Diets prescribed to delay disease progression. Resistance training increases Protein utilization and muscle mass. OBJECTIVE: To determine the efficacy of resistance training in improving Protein utilization and muscle mass in patients with chronic renal insufficiency treated with a Low-Protein Diet. DESIGN: Randomized, controlled trial. SETTING: Tufts University, Boston, Massachusetts. PATIENTS: 26 older patients with moderate renal insufficiency (17 men, 9 women) who had achieved stabilization on a Low-Protein Diet. INTERVENTION: During a run-in period of 2 to 8 weeks, patients were instructed and their adherence to the Low-Protein Diet (0.6 g/kg of body weight per day) was evaluated. They were randomly assigned to a Low-Protein Diet plus resistance training (n = 14) or a Low-Protein Diet alone (n = 12) for 12 weeks. MEASUREMENTS: Total body potassium, mid-thigh muscle area, type I and II muscle-fiber cross-sectional area, and Protein turnover. RESULTS: Mean Protein intake was 0.64 +/- 0.07 g/kg per day after stabilization. Total body potassium and type I and II muscle-fiber cross-sectional areas increased in patients who performed resistance training by a mean (+/-SD) of 4% +/- 8%, 24% +/- 31%, and 22% +/- 29%, respectively, compared with those who did not. Leucine oxidation and serum prealbumin levels also improved significantly. Patients assigned to resistance training maintained body weight compared with those who were not. Improvement in muscle strength was significantly greater with resistance training (32% +/- 14%) than without (-13% +/- 20%) (P < 0.001). CONCLUSION: By improving muscle mass, nutritional status, and function, resistance training seems to be effective against the catabolism of a Low-Protein Diet and uremia in patients with renal failure.
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resistance training to counteract the catabolism of a Low Protein Diet in patients with chronic renal insufficiency
Annals of Internal Medicine, 2001Co-Authors: Carmen Castaneda, Patricia L Gordon, Katherine Leigh Uhlin, Andrew S Levey, Joseph J Kehayias, Johanna T Dwyer, Roger A Fielding, Ronenn Roubenoff, Maria Fiatarone A SinghAbstract:By improving muscle mass, nutritional status, and function, resistance training seems to be effective against the catabolism of a Low-Protein Diet and uremia in patients with renal failure.
Carmen Castaneda - One of the best experts on this subject based on the ideXlab platform.
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resistance training to counteract the catabolism of a Low Protein Diet in patients with chronic renal insufficiency a randomized controlled trial
Annals of Internal Medicine, 2001Co-Authors: Carmen Castaneda, Patricia L Gordon, Katherine Leigh Uhlin, Andrew S Levey, Joseph J Kehayias, Johanna T Dwyer, Roger A Fielding, Ronenn Roubenoff, Maria Fiatarone A SinghAbstract:BACKGROUND: Chronic renal insufficiency leads to muscle wasting, which may be exacerbated by Low-Protein Diets prescribed to delay disease progression. Resistance training increases Protein utilization and muscle mass. OBJECTIVE: To determine the efficacy of resistance training in improving Protein utilization and muscle mass in patients with chronic renal insufficiency treated with a Low-Protein Diet. DESIGN: Randomized, controlled trial. SETTING: Tufts University, Boston, Massachusetts. PATIENTS: 26 older patients with moderate renal insufficiency (17 men, 9 women) who had achieved stabilization on a Low-Protein Diet. INTERVENTION: During a run-in period of 2 to 8 weeks, patients were instructed and their adherence to the Low-Protein Diet (0.6 g/kg of body weight per day) was evaluated. They were randomly assigned to a Low-Protein Diet plus resistance training (n = 14) or a Low-Protein Diet alone (n = 12) for 12 weeks. MEASUREMENTS: Total body potassium, mid-thigh muscle area, type I and II muscle-fiber cross-sectional area, and Protein turnover. RESULTS: Mean Protein intake was 0.64 +/- 0.07 g/kg per day after stabilization. Total body potassium and type I and II muscle-fiber cross-sectional areas increased in patients who performed resistance training by a mean (+/-SD) of 4% +/- 8%, 24% +/- 31%, and 22% +/- 29%, respectively, compared with those who did not. Leucine oxidation and serum prealbumin levels also improved significantly. Patients assigned to resistance training maintained body weight compared with those who were not. Improvement in muscle strength was significantly greater with resistance training (32% +/- 14%) than without (-13% +/- 20%) (P < 0.001). CONCLUSION: By improving muscle mass, nutritional status, and function, resistance training seems to be effective against the catabolism of a Low-Protein Diet and uremia in patients with renal failure.
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resistance training to counteract the catabolism of a Low Protein Diet in patients with chronic renal insufficiency
Annals of Internal Medicine, 2001Co-Authors: Carmen Castaneda, Patricia L Gordon, Katherine Leigh Uhlin, Andrew S Levey, Joseph J Kehayias, Johanna T Dwyer, Roger A Fielding, Ronenn Roubenoff, Maria Fiatarone A SinghAbstract:By improving muscle mass, nutritional status, and function, resistance training seems to be effective against the catabolism of a Low-Protein Diet and uremia in patients with renal failure.
Andrew S Levey - One of the best experts on this subject based on the ideXlab platform.
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effect of a very Low Protein Diet on outcomes long term folLow up of the modification of Diet in renal disease mdrd study
American Journal of Kidney Diseases, 2009Co-Authors: Vandana Menon, Andrew S Levey, Joel D Kopple, Xuelei Wang, Gerald J Beck, Allan J Collins, John W Kusek, Tom Greene, Mark J SarnakAbstract:Background The long-term effect of a very Low-Protein Diet on the progression of kidney disease is unknown. We examined the effect of a very Low-Protein Diet on the development of kidney failure and death during long-term folLow-up of the Modification of Diet in Renal Disease (MDRD) Study. Study Design Long-term folLow-up of study B of the MDRD Study (1989-1993). Setting & Participants The MDRD Study examined the effects of Dietary Protein restriction and blood pressure control on progression of kidney disease. This analysis includes 255 trial participants with predominantly stage 4 nondiabetic chronic kidney disease. Intervention A Low-Protein Diet (0.58 g/kg/d) versus a very Low-Protein Diet (0.28 g/kg/d) supplemented with a mixture of essential keto acids and amino acids (0.28 g/kg/d). Outcomes Kidney failure (initiation of dialysis therapy or transplantation) and all-cause mortality until December 31, 2000. Results Kidney failure developed in 227 (89%) participants, 79 (30.9%) died, and 244 (95.7%) reached the composite outcome of either kidney failure or death. Median duration of folLow-up until kidney failure, death, or administrative censoring was 3.2 years, and median time to death was 10.6 years. In the Low-Protein group, 117 (90.7%) participants developed kidney failure, 30 (23.3%) died, and 124 (96.1%) reached the composite outcome. In the very Low-Protein group, 110 (87.3%) participants developed kidney failure, 49 (38.9%) died, and 120 (95.2%) reached the composite outcome. After adjustment for a priori–specified covariates, hazard ratios were 0.83 (95% confidence interval, 0.62 to 1.12) for kidney failure, 1.92 (95% confidence interval, 1.15 to 3.20) for death, and 0.89 (95% confidence interval, 0.67 to 1.18) for the composite outcome in the very Low-Protein Diet group compared with the Low-Protein Diet group. Limitations Lack of Dietary Protein measurements during folLow-up. Conclusion In long-term folLow-up of the MDRD Study, assignment to a very Low-Protein Diet did not delay progression to kidney failure, but appeared to increase the risk of death.
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resistance training to counteract the catabolism of a Low Protein Diet in patients with chronic renal insufficiency a randomized controlled trial
Annals of Internal Medicine, 2001Co-Authors: Carmen Castaneda, Patricia L Gordon, Katherine Leigh Uhlin, Andrew S Levey, Joseph J Kehayias, Johanna T Dwyer, Roger A Fielding, Ronenn Roubenoff, Maria Fiatarone A SinghAbstract:BACKGROUND: Chronic renal insufficiency leads to muscle wasting, which may be exacerbated by Low-Protein Diets prescribed to delay disease progression. Resistance training increases Protein utilization and muscle mass. OBJECTIVE: To determine the efficacy of resistance training in improving Protein utilization and muscle mass in patients with chronic renal insufficiency treated with a Low-Protein Diet. DESIGN: Randomized, controlled trial. SETTING: Tufts University, Boston, Massachusetts. PATIENTS: 26 older patients with moderate renal insufficiency (17 men, 9 women) who had achieved stabilization on a Low-Protein Diet. INTERVENTION: During a run-in period of 2 to 8 weeks, patients were instructed and their adherence to the Low-Protein Diet (0.6 g/kg of body weight per day) was evaluated. They were randomly assigned to a Low-Protein Diet plus resistance training (n = 14) or a Low-Protein Diet alone (n = 12) for 12 weeks. MEASUREMENTS: Total body potassium, mid-thigh muscle area, type I and II muscle-fiber cross-sectional area, and Protein turnover. RESULTS: Mean Protein intake was 0.64 +/- 0.07 g/kg per day after stabilization. Total body potassium and type I and II muscle-fiber cross-sectional areas increased in patients who performed resistance training by a mean (+/-SD) of 4% +/- 8%, 24% +/- 31%, and 22% +/- 29%, respectively, compared with those who did not. Leucine oxidation and serum prealbumin levels also improved significantly. Patients assigned to resistance training maintained body weight compared with those who were not. Improvement in muscle strength was significantly greater with resistance training (32% +/- 14%) than without (-13% +/- 20%) (P < 0.001). CONCLUSION: By improving muscle mass, nutritional status, and function, resistance training seems to be effective against the catabolism of a Low-Protein Diet and uremia in patients with renal failure.
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resistance training to counteract the catabolism of a Low Protein Diet in patients with chronic renal insufficiency
Annals of Internal Medicine, 2001Co-Authors: Carmen Castaneda, Patricia L Gordon, Katherine Leigh Uhlin, Andrew S Levey, Joseph J Kehayias, Johanna T Dwyer, Roger A Fielding, Ronenn Roubenoff, Maria Fiatarone A SinghAbstract:By improving muscle mass, nutritional status, and function, resistance training seems to be effective against the catabolism of a Low-Protein Diet and uremia in patients with renal failure.
Claude Remacle - One of the best experts on this subject based on the ideXlab platform.
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effect of maternal Low Protein Diet and taurine on the vulnerability of adult wistar rat islets to cytokines
Diabetologia, 2004Co-Authors: S Merezak, Brigitte Reusens, Marietherese Ahn, A Renard, Kevin Goosse, L Kalbe, J Tamaritrodriguez, Claude RemacleAbstract:Aims/hypothesis A maternal Low-Protein Diet has been shown to induce an increased susceptibility of fetal islets to cytokines, but this effect can be avoided by maternal taurine supplementation. Here, we question whether these effects persist until adulthood in the offspring, despite the animal having a normal Diet after weaning.
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taurine supplementation to a Low Protein Diet during foetal and early postnatal life restores a normal proliferation and apoptosis of rat pancreatic islets
Diabetologia, 2002Co-Authors: S Boujendar, Brigitte Reusens, S Merezak, Marietherese Ahn, Edith Arany, D J Hill, Claude RemacleAbstract:Aims/hypothesis. In our previous studies a Low Protein Diet (8% vs 20%) given during foetal and early postnatal life induced abnormal development of the endocrine pancreas; beta-cell mass and islet-cell proliferation were reduced while apoptosis was increased. Taurine, an important amino acid for development was also reduced in maternal and foetal plasma of Protein deficient animals. In this study we aim to evaluate the role of taurine in the alterations observed in rats after a Low Protein Diet.
Joseph J Kehayias - One of the best experts on this subject based on the ideXlab platform.
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resistance training to counteract the catabolism of a Low Protein Diet in patients with chronic renal insufficiency a randomized controlled trial
Annals of Internal Medicine, 2001Co-Authors: Carmen Castaneda, Patricia L Gordon, Katherine Leigh Uhlin, Andrew S Levey, Joseph J Kehayias, Johanna T Dwyer, Roger A Fielding, Ronenn Roubenoff, Maria Fiatarone A SinghAbstract:BACKGROUND: Chronic renal insufficiency leads to muscle wasting, which may be exacerbated by Low-Protein Diets prescribed to delay disease progression. Resistance training increases Protein utilization and muscle mass. OBJECTIVE: To determine the efficacy of resistance training in improving Protein utilization and muscle mass in patients with chronic renal insufficiency treated with a Low-Protein Diet. DESIGN: Randomized, controlled trial. SETTING: Tufts University, Boston, Massachusetts. PATIENTS: 26 older patients with moderate renal insufficiency (17 men, 9 women) who had achieved stabilization on a Low-Protein Diet. INTERVENTION: During a run-in period of 2 to 8 weeks, patients were instructed and their adherence to the Low-Protein Diet (0.6 g/kg of body weight per day) was evaluated. They were randomly assigned to a Low-Protein Diet plus resistance training (n = 14) or a Low-Protein Diet alone (n = 12) for 12 weeks. MEASUREMENTS: Total body potassium, mid-thigh muscle area, type I and II muscle-fiber cross-sectional area, and Protein turnover. RESULTS: Mean Protein intake was 0.64 +/- 0.07 g/kg per day after stabilization. Total body potassium and type I and II muscle-fiber cross-sectional areas increased in patients who performed resistance training by a mean (+/-SD) of 4% +/- 8%, 24% +/- 31%, and 22% +/- 29%, respectively, compared with those who did not. Leucine oxidation and serum prealbumin levels also improved significantly. Patients assigned to resistance training maintained body weight compared with those who were not. Improvement in muscle strength was significantly greater with resistance training (32% +/- 14%) than without (-13% +/- 20%) (P < 0.001). CONCLUSION: By improving muscle mass, nutritional status, and function, resistance training seems to be effective against the catabolism of a Low-Protein Diet and uremia in patients with renal failure.
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resistance training to counteract the catabolism of a Low Protein Diet in patients with chronic renal insufficiency
Annals of Internal Medicine, 2001Co-Authors: Carmen Castaneda, Patricia L Gordon, Katherine Leigh Uhlin, Andrew S Levey, Joseph J Kehayias, Johanna T Dwyer, Roger A Fielding, Ronenn Roubenoff, Maria Fiatarone A SinghAbstract:By improving muscle mass, nutritional status, and function, resistance training seems to be effective against the catabolism of a Low-Protein Diet and uremia in patients with renal failure.
