Lupus Vulgaris

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N P Haas - One of the best experts on this subject based on the ideXlab platform.

  • squamous cell carcinoma in Lupus Vulgaris
    Journal Der Deutschen Dermatologischen Gesellschaft, 2004
    Co-Authors: Jens Kimmritz, Barbara Hermes, Christiane Schewe, N P Haas
    Abstract:

    Lupus Vulgaris and carcinoma in lupo have become rare events that take place in the developed countries only under special circumstances. A 53-year-old woman developed such a carcinoma. She suffered from alcoholism, a well known risk factor for tuberculosis. The diagnosis of Lupus Vulgaris was confirmed by biopsy when an erythematous lesion on her arm that had been present for 25 years enlarged and subsequently ulcerated. Chemotherapy was discontinued because of lack of compliance and the ulcer grew markedly over the following 16 months. Therefore the entire lesion was excised. Histology showed a squamous cell carcinoma within the ulcer. Neither further systemic manifestations of tuberculosis nor metastases of the carcinoma were found. Under continuous combined antituberculous therapy, the patient remained free of symptoms. This case underlines the problems associated with a disease that has been nearly forgotten in the western countries. It also shows that alcoholism is a risk factor for tuberculosis, along with debilitating diseases such as lymphoma and AIDS as well as immunosuppressive therapy.

Jens Kimmritz - One of the best experts on this subject based on the ideXlab platform.

  • squamous cell carcinoma in Lupus Vulgaris
    Journal Der Deutschen Dermatologischen Gesellschaft, 2004
    Co-Authors: Jens Kimmritz, Barbara Hermes, Christiane Schewe, N P Haas
    Abstract:

    Lupus Vulgaris and carcinoma in lupo have become rare events that take place in the developed countries only under special circumstances. A 53-year-old woman developed such a carcinoma. She suffered from alcoholism, a well known risk factor for tuberculosis. The diagnosis of Lupus Vulgaris was confirmed by biopsy when an erythematous lesion on her arm that had been present for 25 years enlarged and subsequently ulcerated. Chemotherapy was discontinued because of lack of compliance and the ulcer grew markedly over the following 16 months. Therefore the entire lesion was excised. Histology showed a squamous cell carcinoma within the ulcer. Neither further systemic manifestations of tuberculosis nor metastases of the carcinoma were found. Under continuous combined antituberculous therapy, the patient remained free of symptoms. This case underlines the problems associated with a disease that has been nearly forgotten in the western countries. It also shows that alcoholism is a risk factor for tuberculosis, along with debilitating diseases such as lymphoma and AIDS as well as immunosuppressive therapy.

Fang Fang - One of the best experts on this subject based on the ideXlab platform.

Murat Demiriz - One of the best experts on this subject based on the ideXlab platform.

  • annular Lupus Vulgaris an unusual case undiagnosed for five years
    European Journal of Dermatology, 2007
    Co-Authors: Miizeyyen Gonul, Arzu Kilic, Seray Kulcu Cakmak, Ulker Gul, Oguzhan Kocak, Murat Demiriz
    Abstract:

    Tuberculosis is still a serious problem in both developing and developed countries. It is often confused with various cutaneous disorders both clinically and histopathologically.A 46-year-old woman attended our clinic with progressive, asymptomatic, annular skin lesions on her right upper extremity for 5 years. She had received many different therapies for these lesions at other instutions previously but these medications were not effective and the lesions deteriorated. On dermatological examination, well-demarcated, irregular bordered, violaceous colored, elevated and crusted annular lesions on her right hand dorsum and forearm were observed. She was diagnosed as having Lupus Vulgaris clinically and histopathologically. Antituberculosis therapy was administered and regression of the lesions started in the second week of medication.We report a case of long-standing, undiagnosed and uncommon, annular form of Lupus Vulgaris. We want to stress that clinical and histopathological findings are still important for the diagnosis of cutaneous tuberculosis.

Barbara Hermes - One of the best experts on this subject based on the ideXlab platform.

  • squamous cell carcinoma in Lupus Vulgaris
    Journal Der Deutschen Dermatologischen Gesellschaft, 2004
    Co-Authors: Jens Kimmritz, Barbara Hermes, Christiane Schewe, N P Haas
    Abstract:

    Lupus Vulgaris and carcinoma in lupo have become rare events that take place in the developed countries only under special circumstances. A 53-year-old woman developed such a carcinoma. She suffered from alcoholism, a well known risk factor for tuberculosis. The diagnosis of Lupus Vulgaris was confirmed by biopsy when an erythematous lesion on her arm that had been present for 25 years enlarged and subsequently ulcerated. Chemotherapy was discontinued because of lack of compliance and the ulcer grew markedly over the following 16 months. Therefore the entire lesion was excised. Histology showed a squamous cell carcinoma within the ulcer. Neither further systemic manifestations of tuberculosis nor metastases of the carcinoma were found. Under continuous combined antituberculous therapy, the patient remained free of symptoms. This case underlines the problems associated with a disease that has been nearly forgotten in the western countries. It also shows that alcoholism is a risk factor for tuberculosis, along with debilitating diseases such as lymphoma and AIDS as well as immunosuppressive therapy.