The Experts below are selected from a list of 129 Experts worldwide ranked by ideXlab platform
Ulrich Joos - One of the best experts on this subject based on the ideXlab platform.
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surgical treatment of persistent Macrocheilia in patients with melkersson rosenthal syndrome and cheilitis granulomatosa
Archives of Dermatology, 2005Co-Authors: Birgit Kruselosler, Dagmar Presser, Dieter Metze, Ulrich JoosAbstract:Background Various conservative methods for treatment of labial swelling in patients with cheilitis granulomatosa have been attempted, often with only moderate success and sometimes with persistent disfiguring lip swelling. Severe Macrocheilia can produce an unaesthetic facial deformity associated with functional disturbances. In patients with persistent Macrocheilia, reduction cheiloplasty with excision of excess tissue may be indicated when conservative treatment has proven ineffective in reducing swelling but may have been successful in stabilizing disease. Objective To evaluate long-term results after reduction cheiloplasty in patients with Macrocheilia caused by Melkersson-Rosenthal syndrome or cheilitis granulomatosa. Design Follow-up study in 7 patients with severe persisting Macrocheilia, including 3 patients with Melkersson-Rosenthal syndrome and 4 patients with cheilitis granulomatosa in a stable state of disease, treated by reduction cheiloplasty at our hospital between January 1, 1987, and December 31, 2002. Preoperative and postoperative medical histories were obtained, and criteria for the success of surgical treatment were evaluated by clinical examination. Different techniques of reduction cheiloplasty are described and demonstrated in representative cases of severe Macrocheilia. Results Surgical treatment in all 7 patients showed satisfying aesthetic and functional outcomes that persisted throughout follow-up (median follow-up, 6.5 years). Conclusions Reduction cheiloplasty is an effective method to correct persistent Macrocheilia and improve lip aesthetics in patients with Melkersson-Rosenthal syndrome or granulomatous cheilitis in the persistent state of disease. With careful planning, proper sequencing of treatment, and proficiency in the various surgical techniques, optimal results can be achieved.
Michael T. Longaker - One of the best experts on this subject based on the ideXlab platform.
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Vascular lip enlargement: Part II. Port-wine Macrocheilia--tenets of therapy based on normative values.
Plastic and reconstructive surgery, 1997Co-Authors: Barry M. Zide, Paul M. Glat, Frank Stile, Michael T. LongakerAbstract:Port-wine (capillary) vascular malformations that enlarge the lips (port-wine Macrocheilia) are challenging reconstructive problems which, as a result, often go untreated. The surgical management of these lesions is not straightforward. Sacrification by laser to diminish the discoloration has been performed with good results in some cases. However, laser treatment does little to correct three-dimensional tissue deformities such as Macrocheilia, which must be addressed surgically. We present our experience with the treatment of port-wine Macrocheilia in 11 patients over the 10-year period between 1983 and 1994. Basic principles for surgical and nonsurgical treatment of these patients are also discussed. Normative data about lip dimensions are important to surgical planning. We used 40 male and female volunteers, all less than 30 years of age, as a source for measuring normal lip dimensions, thereby creating a normative database. Preestablished points in the labial and perioral region were marked. Measurements were taken and then averaged. This inforrmation was used as a guide for surgical excision of large defects in some patients. In addition, in both the lower and the upper lip, if the opposite side is uninvolved, this database could serve as a template for reconstruction of the affected side. Between 1983 and 1994, 11 patients underwent surgery for port-wine Macrocheilia. Of the 11 patients, 1 had previous treatment conisting of laser sacrification. Four patients had port-wine vascular malformations involving the upper lip alone, four involved the lower lip alone, and three involved both lips. In six patients, other areas of the face and body were also involved. Our experience has led us to perform earlier surgical intervention than has previously been described for these patients. Basic reconstructive surgical principles and planning based on normative data and templates can lead to excellent results.
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Vascular lip enlargement: Part I. Hemangiomas--tenets of therapy.
Plastic and reconstructive surgery, 1997Co-Authors: Barry M. Zide, Paul M. Glat, Frank Stile, Michael T. LongakerAbstract:Vascular lesions involving the lips pose a difficult problem for both the surgeon and patient. Their removal by surgery may result in greater disfigurement and impairment than the original lesion. When nonsurgical modalities fail, using a well-planned strategy of sequential procedures can provide excellent results. Many hemangioma patients require judicious serial debulking of excess tissue mass, whereas enlargement from port-wine lesions may require direct aggressive surgery. Over a 10-year period, 38 patients underwent surgery for treatment of vascular lip enlargement. In 27 patients, the lip deformities were caused by hemangiomas. The remaining 11 patients had Macrocheilia associated with port-wine vascular malformations. This paper specifically addresses hemangiomas of the lips, tenets for their removal, and reduction strategies. Of the 27 patients with hemangiomas involving the lips, 12 had had some form of previous treatment including corticosteroids (4 patients), embolization (3 patients), laser (3 patients), and interferon (2 patients). All 12 of these patients had unsatisfactory results. Specific tenets for the surgical management of these patients are presented, The distribution of the facial hemangiomas was as follows: 15 patients had isolated involvement of the upper lip, 7 lesions involved the lower lip alone and 5 involved both upper and lower lips. Additionally, 10 of these lesions involved the cheek(s), nose, or chin to some degree. Six patients experienced some form of functional impairment before our evaluation including difficulty with eating or drinking, visual obstruction, and psychosocial problems. All operations were performed following several principles established by the senior surgeon (B.M.Z.). By following the tenets presented in this report, he has achieved near-normal lip form, giving the patient marked improvement in appearance and function.
Eduardo Fonseca - One of the best experts on this subject based on the ideXlab platform.
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Lower lip hypertrophy secondary to port-wine stain: combined surgical and carbon dioxide laser treatment.
Dermatologic Surgery, 2004Co-Authors: Jesús Del Pozo, José Manuel Pazos, Eduardo FonsecaAbstract:Background. Port-wine stains (PWSs) are capillary malformations that usually show progressive stasis of the vascular channels and cause slow hyperplasia of the soft and hard tissues. When these lesions involve the lower lip, Macrocheilia may be developed along the time. Vascular-specific lasers are not adequate to correct these three-dimensional tissue deformities, and surgical management becomes necessary, resulting in considerable morbidity and aesthetic disturbances. Objective. To report a case of Macrocheilia secondary to PWS treated by combination of surgery and carbon dioxide laser. Methods. A 51-year-old man with Macrocheilia of the lower lip and severe functional impairment, secondary to long evolution PWS, received treatment with carbon dioxide laser vaporization and minimal surgical correction, resulting in significant improvement of the lower lip hypertrophy, good aesthetic and functional status, and preservation of the muscular function. Conclusions. Combined carbon dioxide laser and surgery treatment may constitute a valuable alternative in treatment of Macrocheilia secondary to PWS because bleeding risk is minimized and improves the preservation of muscular function and aesthetic results in relationship to conventional surgical approaches.
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Lower lip hypertrophy secondary to port-wine stain: combined surgical and carbon dioxide laser treatment.
Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2004Co-Authors: Jesús Del Pozo, José Manuel Pazos, Eduardo FonsecaAbstract:Port-wine stains (PWSs) are capillary malformations that usually show progressive stasis of the vascular channels and cause slow hyperplasia of the soft and hard tissues. When these lesions involve the lower lip, Macrocheilia may be developed along the time. Vascular-specific lasers are not adequate to correct these three-dimensional tissue deformities, and surgical management becomes necessary, resulting in considerable morbidity and aesthetic disturbances. To report a case of Macrocheilia secondary to PWS treated by combination of surgery and carbon dioxide laser. A 51-year-old man with Macrocheilia of the lower lip and severe functional impairment, secondary to long evolution PWS, received treatment with carbon dioxide laser vaporization and minimal surgical correction, resulting in significant improvement of the lower lip hypertrophy, good aesthetic and functional status, and preservation of the muscular function. Combined carbon dioxide laser and surgery treatment may constitute a valuable alternative in treatment of Macrocheilia secondary to PWS because bleeding risk is minimized and improves the preservation of muscular function and aesthetic results in relationship to conventional surgical approaches.
Anamika Pradeep - One of the best experts on this subject based on the ideXlab platform.
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Localized Attachment Loss in Pendred Syndrome: Incidental?
Journal of periodontology, 2007Co-Authors: C.g. Dileep Sharma, Anamika PradeepAbstract:Background: Pendred syndrome is a rare, inherited, autosomal recessive disorder with an iodine organification defect of thyroxin produced by the thyroid gland. Its clinical features include sensorineural hearing loss, classically congenital and prelingual, and goiter.Methods: This is the first case report of Pendred syndrome in the dental literature with oral findings that include localized extensive attachment loss involving mandibular incisor teeth and idiopathic hypercementosis involving multiple teeth in addition to other oral manifestations, suggesting hypothyroidism-like macroglossia and Macrocheilia. Furthermore, serum alkaline phosphatase along with inorganic calcium and phosphate levels were also elevated. Peripheral neutrophil function test suggested a defective function of neutrophils.Results: Management of the case included augmenting thyroxin supplementation, in consultation with an endocrinologist, and extraction of hopeless mandibular central incisors followed by placement of immediate tran...
Birgit Kruselosler - One of the best experts on this subject based on the ideXlab platform.
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surgical treatment of persistent Macrocheilia in patients with melkersson rosenthal syndrome and cheilitis granulomatosa
Archives of Dermatology, 2005Co-Authors: Birgit Kruselosler, Dagmar Presser, Dieter Metze, Ulrich JoosAbstract:Background Various conservative methods for treatment of labial swelling in patients with cheilitis granulomatosa have been attempted, often with only moderate success and sometimes with persistent disfiguring lip swelling. Severe Macrocheilia can produce an unaesthetic facial deformity associated with functional disturbances. In patients with persistent Macrocheilia, reduction cheiloplasty with excision of excess tissue may be indicated when conservative treatment has proven ineffective in reducing swelling but may have been successful in stabilizing disease. Objective To evaluate long-term results after reduction cheiloplasty in patients with Macrocheilia caused by Melkersson-Rosenthal syndrome or cheilitis granulomatosa. Design Follow-up study in 7 patients with severe persisting Macrocheilia, including 3 patients with Melkersson-Rosenthal syndrome and 4 patients with cheilitis granulomatosa in a stable state of disease, treated by reduction cheiloplasty at our hospital between January 1, 1987, and December 31, 2002. Preoperative and postoperative medical histories were obtained, and criteria for the success of surgical treatment were evaluated by clinical examination. Different techniques of reduction cheiloplasty are described and demonstrated in representative cases of severe Macrocheilia. Results Surgical treatment in all 7 patients showed satisfying aesthetic and functional outcomes that persisted throughout follow-up (median follow-up, 6.5 years). Conclusions Reduction cheiloplasty is an effective method to correct persistent Macrocheilia and improve lip aesthetics in patients with Melkersson-Rosenthal syndrome or granulomatous cheilitis in the persistent state of disease. With careful planning, proper sequencing of treatment, and proficiency in the various surgical techniques, optimal results can be achieved.
