The Experts below are selected from a list of 1800 Experts worldwide ranked by ideXlab platform
Andrew R Scott - One of the best experts on this subject based on the ideXlab platform.
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neonatal Macroglossia demographics cost of care and associated comorbidities
The Cleft Palate-Craniofacial Journal, 2018Co-Authors: Jonathan C Simmonds, Anju K Patel, Nicholas S Mader, Nicholas R Mildenhall, Andrew R ScottAbstract:Objectives:To examine the birth prevalence of congenital Macroglossia and identify demographic variables and comorbidities that may influence length of stay and cost of care.Study Design:Retrospect...
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national trends in tongue reduction surgery for Macroglossia in children
Journal of Cranio-maxillofacial Surgery, 2018Co-Authors: Jonathan C Simmonds, Anju K Patel, Nicholas S Mader, Andrew R ScottAbstract:Abstract Objectives To examine the frequency of partial glossectomy performed for the indication of Macroglossia in children within the United States, assessing for differences in rates of intervention across various demographics. To identify potential morbidities associated with partial glossectomy in this population and determine how such factors may influence length of stay and cost of admission following tongue reduction surgery. Study Design Retrospective cross-sectional study. Setting The Kids' Inpatient Database 2003, 2006, 2009, and 2012. Subjects Patients under age 5 diagnosed with Macroglossia who underwent partial glossectomy. Methods Demographics were analyzed and cross tabulations, linear regression modeling, and multivariate analysis were performed. Results During the four-years studied, partial glossectomy was performed in 196 children under age 5 with Macroglossia. A disproportionately higher rate of intervention was seen in white children (p = 0.001), patients undergoing surgery in the mid-west (p Conclusion Partial glossectomy for Macroglossia is typically performed prior to age 2 in the United States. A higher rate of intervention is seen in white children, those who have surgery in the mid-west and affluent children even when controlling for confounding variables. Level of evidence III.
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Supplemental Material, DS2_CPCJ_10.1177_1055665618760898 - Neonatal Macroglossia: Demographics, Cost of Care, and Associated Comorbidities
2018Co-Authors: Jonathan C Simmonds, Anju K Patel, Nicholas S Mader, Nicholas R Mildenhall, Andrew R ScottAbstract:Supplemental Material, DS2_CPCJ_10.1177_1055665618760898 for Neonatal Macroglossia: Demographics, Cost of Care, and Associated Comorbidities by Jonathan C. Simmonds, Anju K. Patel, Nicholas R. Mildenhall, Nicholas S. Mader, and Andrew R. Scott in The Cleft Palate-Craniofacial Journal
Jonathan C Simmonds - One of the best experts on this subject based on the ideXlab platform.
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neonatal Macroglossia demographics cost of care and associated comorbidities
The Cleft Palate-Craniofacial Journal, 2018Co-Authors: Jonathan C Simmonds, Anju K Patel, Nicholas S Mader, Nicholas R Mildenhall, Andrew R ScottAbstract:Objectives:To examine the birth prevalence of congenital Macroglossia and identify demographic variables and comorbidities that may influence length of stay and cost of care.Study Design:Retrospect...
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national trends in tongue reduction surgery for Macroglossia in children
Journal of Cranio-maxillofacial Surgery, 2018Co-Authors: Jonathan C Simmonds, Anju K Patel, Nicholas S Mader, Andrew R ScottAbstract:Abstract Objectives To examine the frequency of partial glossectomy performed for the indication of Macroglossia in children within the United States, assessing for differences in rates of intervention across various demographics. To identify potential morbidities associated with partial glossectomy in this population and determine how such factors may influence length of stay and cost of admission following tongue reduction surgery. Study Design Retrospective cross-sectional study. Setting The Kids' Inpatient Database 2003, 2006, 2009, and 2012. Subjects Patients under age 5 diagnosed with Macroglossia who underwent partial glossectomy. Methods Demographics were analyzed and cross tabulations, linear regression modeling, and multivariate analysis were performed. Results During the four-years studied, partial glossectomy was performed in 196 children under age 5 with Macroglossia. A disproportionately higher rate of intervention was seen in white children (p = 0.001), patients undergoing surgery in the mid-west (p Conclusion Partial glossectomy for Macroglossia is typically performed prior to age 2 in the United States. A higher rate of intervention is seen in white children, those who have surgery in the mid-west and affluent children even when controlling for confounding variables. Level of evidence III.
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Supplemental Material, DS2_CPCJ_10.1177_1055665618760898 - Neonatal Macroglossia: Demographics, Cost of Care, and Associated Comorbidities
2018Co-Authors: Jonathan C Simmonds, Anju K Patel, Nicholas S Mader, Nicholas R Mildenhall, Andrew R ScottAbstract:Supplemental Material, DS2_CPCJ_10.1177_1055665618760898 for Neonatal Macroglossia: Demographics, Cost of Care, and Associated Comorbidities by Jonathan C. Simmonds, Anju K. Patel, Nicholas R. Mildenhall, Nicholas S. Mader, and Andrew R. Scott in The Cleft Palate-Craniofacial Journal
Chiharu Matsuda - One of the best experts on this subject based on the ideXlab platform.
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Macroglossia in advanced amyotrophic lateral sclerosis
Muscle & Nerve, 2016Co-Authors: Chiharu Matsuda, Toshio Shimizu, Yuki Nakayama, Michiko Haraguchi, Chiyoko Hakuta, Yumi Itagaki, Akiko Ogura, Kanako Murata, Masato TairaAbstract:Introduction An enlarged tongue (Macroglossia) has been reported in advanced-stage patients with amyotrophic lateral sclerosis (ALS). Methods In this study we examined the prevalence of Macroglossia and analyzed clinical correlations in 65 ALS patients on tracheostomy-invasive ventilation (TIV). Results Macroglossia was found in 22 patients (33.8%). Compared with those without Macroglossia, patients with Macroglossia had a younger age of onset, longer duration of disease and TIV use, lower ALS Functional Rating Scale score, higher body mass index, lower energy intake, more severe communication impairment, and lower oral function. Logistic multivariate analysis showed that body mass index (BMI; P = 0.007) and communication impairment (P = 0.029) were significantly correlated with Macroglossia. The duration of TIV use was at the cut-off level of significance (P = 0.05). Conclusions Macroglossia may be the result of overfeeding and replacement by fat during long-term TIV use in patients with advanced ALS. Muscle Nerve, 2016 Muscle Nerve 54: 386-390, 2016.
Becky L Mcgrawwall - One of the best experts on this subject based on the ideXlab platform.
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massive Macroglossia after posterior fossa surgery in the prone position
Journal of Neurosurgical Anesthesiology, 1998Co-Authors: Evan G Pivalizza, J Katz, Sandip Singh, Wei Liu, Becky L McgrawwallAbstract:We describe an unusual case of severe postoperative Macroglossia after posterior fossa surgery in the prone position, and review potential causative factors and prophylactic measures that may alleviate this serious complication.
Edward J Kasarskis - One of the best experts on this subject based on the ideXlab platform.
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Macroglossia in amyotrophic lateral sclerosis
JAMA Neurology, 2013Co-Authors: Heather R Mckee, Edward J Escott, Douglas D Damm, Edward J KasarskisAbstract:Importance We encountered 2 patients with amyotrophic lateral sclerosis (ALS) with tongue enlargement and protrusion outside the oral cavity (Macroglossia). To our knowledge, the relationship between Macroglossia and ALS has not been reported in the literature. The objective of this article was to describe the clinical characteristics, imaging, and pathology of Macroglossia in ALS and to develop a hypothesis regarding its pathophysiology. Observations Two patients developed progressive weakness at age 54 and 40 years. Both patients exhibited dysarthria, dysphagia, tongue atrophy, neck extensor weakness, and weakness of jaw closure during a 1-year period. Both required tracheostomy and mechanical ventilation and afterward developed Macroglossia. A 3-dimensional–reconstructed sagittal computed tomographic image confirmed tongue protrusion outside the oral cavity with focal compression and showed the transition from the atrophied part of the tongue in the oropharynx to the edematous part outside the mouth. Tongue biopsy demonstrated fatty replacement and fascicles of degenerative muscle. Conclusions and Relevance We are unaware of previous reports of Macroglossia in ALS/motor neuron disease. Given the paucity of case material, we speculated that this is an extremely rare complication of ALS. Based on this series, we propose a pathophysiological mechanism by reviewing imaging and tongue biopsy.
