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Tetsuro Oshika - One of the best experts on this subject based on the ideXlab platform.
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Changes in aniseikonia and influencing-factors following successful macula-off retinal detachment surgery.
Scientific Reports, 2019Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro OshikaAbstract:This study investigated the changes in the severity of aniseikonia after surgery for macula-off retinal detachment (RD), and the relationship between aniseikonia and retinal microstructures. The study included 26 eyes of 26 patients undergoing RD surgery. Visual acuity was measured preoperatively, and at 3, 6, and 12 months postoperatively. Degree of aniseikonia and OCT images were obtained at 3, 6, and 12 months postoperatively. The aniseikonia values (mean ± standard deviation) at 3, 6, and 12 months postoperatively were −5.3 ± 4.2%, −4.4 ± 4.4%, and −3.1 ± 3.2%, respectively. Significant improvement was observed from 3 to 12 months postoperatively (P = 0.001). Twelve months postoperatively, 14 eyes had micropsia, 1 eye had Macropsia, and 11 eyes were free of aniseikonia. Stepwise multiple regression analyses revealed that the severity of aniseikonia at 12 months postoperatively was significantly associated with postoperative development of cystoid macular edema (CME) and epiretinal membrane (ERM), as well as area of preoperative RD. In conclusion, although aniseikonia was gradually relieved after RD surgery during a 1-year follow-up period, approximately half of patients had aniseikonia and almost all of them had micropsia. Aniseikonia was associated with presence of postoperative CME, ERM, and area of preoperative RD.
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Changes in aniseikonia and influencing-factors following successful macula-off retinal detachment surgery.
Scientific Reports, 2019Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro OshikaAbstract:This study investigated the changes in the severity of aniseikonia after surgery for macula-off retinal detachment (RD), and the relationship between aniseikonia and retinal microstructures. The study included 26 eyes of 26 patients undergoing RD surgery. Visual acuity was measured preoperatively, and at 3, 6, and 12 months postoperatively. Degree of aniseikonia and OCT images were obtained at 3, 6, and 12 months postoperatively. The aniseikonia values (mean ± standard deviation) at 3, 6, and 12 months postoperatively were −5.3 ± 4.2%, −4.4 ± 4.4%, and −3.1 ± 3.2%, respectively. Significant improvement was observed from 3 to 12 months postoperatively (P = 0.001). Twelve months postoperatively, 14 eyes had micropsia, 1 eye had Macropsia, and 11 eyes were free of aniseikonia. Stepwise multiple regression analyses revealed that the severity of aniseikonia at 12 months postoperatively was significantly associated with postoperative development of cystoid macular edema (CME) and epiretinal membrane (ERM), as well as area of preoperative RD. In conclusion, although aniseikonia was gradually relieved after RD surgery during a 1-year follow-up period, approximately half of patients had aniseikonia and almost all of them had micropsia. Aniseikonia was associated with presence of postoperative CME, ERM, and area of preoperative RD.
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Aniseikonia in various retinal disorders
Graefe's Archive for Clinical and Experimental Ophthalmology, 2017Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro OshikaAbstract:Purpose The purpose was to quantify and compare the severity of aniseikonia in patients undergoing vitrectomy for various retinal disorders. Methods We studied 357 patients with retinal disorders including epiretinal membrane (ERM), macular hole (MH), cystoid macular edema with branch / central retinal vein occlusion (BRVO-CME / CRVO-CME), diabetic macular edema (DME), macula-off rhegmatogenous retinal detachment (M-off RD), and macula-on RD (M-on RD) as well as 31 normal controls. The amount of aniseikonia was measured using the New Aniseikonia Test preoperatively and at 6 months postoperatively. Results Of all patients, 59% presented aniseikonia. Preoperative and postoperative mean aniseikonia were 4.0 ± 4.1% and 3.0 ± 3.6%, respectively. In particular, 68% of patients with ERM had Macropsia, and approximately half of MH, RVO-CME, DME, and M-off RD patients had micropsia. Preoperative aniseikonia was significantly severe in ERM than in other disorders. Vitrectomy improved aniseikonia only in MH, while visual acuity was improved in all disorders except CRVO-CME. Conclusion More than half of the patients showed aniseikonia preoperatively. A majority of ERM patients exhibited Macropsia, whereas MH, RVO-CME, DME, and macula-off RD patients presented micropsia. The aniseikonia score was greatest in ERM patients. In most retinal disorders, surgery significantly improved visual acuity, but not aniseikonia.
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Aniseikonia and Foveal Microstructure in Patients with Idiopathic Macular Hole
Ophthalmology, 2016Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Yuki Moriya, Tomoya Murakami, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro OshikaAbstract:Purpose To quantify the severity of aniseikonia in patients undergoing vitrectomy for idiopathic macular hole (MH) and to examine any relationship between aniseikonia and the foveal microstructure. Design Prospective, consecutive, interventional case series. Participants We included 56 eyes of 56 patients who underwent vitrectomy to treat idiopathic MH. Methods We examined visual acuity, aniseikonia using the New Aniseikonia Test, and foveal structure using optical coherence tomography (OCT) before and 3, 6, and 12 months after surgery. Based on OCT images, minimum and base diameters of MH, height of MH, and defect lengths of the external limiting membrane (ELM), ellipsoid zone, and interdigitation zone were assessed. Main Outcome Measures Degree of aniseikonia before and after surgery. Results The mean aniseikonia was −3.2±4.6%, ranging from −15.5% to +5.0%. Of the patients, 55% had micropsia, 7% had Macropsia, and 38% had no aniseikonia. The mean absolute value of aniseikonia improved significantly from 3.8±4.1% before surgery to 1.0±1.5% at 12 months after surgery ( P P P P P Conclusions Approximately half of MH patients had micropsia. Vitrectomy for MH improved aniseikonia. Preoperative aniseikonia was associated with MH size and the defect length of ELM.
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Aniseikonia and Foveal Microstructure after Retinal Detachment Surgery.
Investigative Ophthalmology & Visual Science, 2014Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro OshikaAbstract:PURPOSE. To quantify aniseikonia after successful surgical repair of rhegmatogenous retinal detachment (RD), and to investigate the relationship between the severity of postoperative aniseikonia and retinal microstructures as well as clinical parameters. METHODS. The study included 106 eyes of 106 patients, without any history of ocular disease/ surgery and with less than 2 diopters of anisometropia, who had undergone successful retinal reattachment surgery. Aniseikonia was measured with the New Aniseikonia Test, and foveal microstructure was assessed with spectral-domain optical coherence tomography (OCT) at 6 months postoperatively. RESULTS. Twenty-eight of 106 patients (26%) had micropsia; 17 patients (16%) had Macropsia; and 61 patients (58%) had no aniseikonia. The mean absolute value of aniseikonia was 2.3 6 2.9% (range, � 12.5% to þ12.0%). Of 57 eyes with macula-on RD, 3 had micropsia and 12 had Macropsia. Of 49 eyes with macula-off RD, 25 had micropsia and 5 had Macropsia. Eyes with micropsia mostly exhibited persistent or transient cystoid macular edema, subretinal fluid, hyperreflective or disruption of IS/OS line, while most of the eyes with Macropsia presented epiretinal membrane. Stepwise multiple regression analysis revealed that postoperative bestcorrected visual acuity and the area of RD were significantly relevant to the mean absolute value of aniseikonia. CONCLUSIONS. These results suggested that approximately half of patients with successful repair of RD had aniseikonia. Eyes with macula-off RD tended to show micropsia, while those with macula-on RD mostly presented Macropsia. Micropsia and Macropsia were primarily caused by respective specific abnormal structures at the foveal region.
Fumiki Okamoto - One of the best experts on this subject based on the ideXlab platform.
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Changes in aniseikonia and influencing-factors following successful macula-off retinal detachment surgery.
Scientific Reports, 2019Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro OshikaAbstract:This study investigated the changes in the severity of aniseikonia after surgery for macula-off retinal detachment (RD), and the relationship between aniseikonia and retinal microstructures. The study included 26 eyes of 26 patients undergoing RD surgery. Visual acuity was measured preoperatively, and at 3, 6, and 12 months postoperatively. Degree of aniseikonia and OCT images were obtained at 3, 6, and 12 months postoperatively. The aniseikonia values (mean ± standard deviation) at 3, 6, and 12 months postoperatively were −5.3 ± 4.2%, −4.4 ± 4.4%, and −3.1 ± 3.2%, respectively. Significant improvement was observed from 3 to 12 months postoperatively (P = 0.001). Twelve months postoperatively, 14 eyes had micropsia, 1 eye had Macropsia, and 11 eyes were free of aniseikonia. Stepwise multiple regression analyses revealed that the severity of aniseikonia at 12 months postoperatively was significantly associated with postoperative development of cystoid macular edema (CME) and epiretinal membrane (ERM), as well as area of preoperative RD. In conclusion, although aniseikonia was gradually relieved after RD surgery during a 1-year follow-up period, approximately half of patients had aniseikonia and almost all of them had micropsia. Aniseikonia was associated with presence of postoperative CME, ERM, and area of preoperative RD.
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Changes in aniseikonia and influencing-factors following successful macula-off retinal detachment surgery.
Scientific Reports, 2019Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro OshikaAbstract:This study investigated the changes in the severity of aniseikonia after surgery for macula-off retinal detachment (RD), and the relationship between aniseikonia and retinal microstructures. The study included 26 eyes of 26 patients undergoing RD surgery. Visual acuity was measured preoperatively, and at 3, 6, and 12 months postoperatively. Degree of aniseikonia and OCT images were obtained at 3, 6, and 12 months postoperatively. The aniseikonia values (mean ± standard deviation) at 3, 6, and 12 months postoperatively were −5.3 ± 4.2%, −4.4 ± 4.4%, and −3.1 ± 3.2%, respectively. Significant improvement was observed from 3 to 12 months postoperatively (P = 0.001). Twelve months postoperatively, 14 eyes had micropsia, 1 eye had Macropsia, and 11 eyes were free of aniseikonia. Stepwise multiple regression analyses revealed that the severity of aniseikonia at 12 months postoperatively was significantly associated with postoperative development of cystoid macular edema (CME) and epiretinal membrane (ERM), as well as area of preoperative RD. In conclusion, although aniseikonia was gradually relieved after RD surgery during a 1-year follow-up period, approximately half of patients had aniseikonia and almost all of them had micropsia. Aniseikonia was associated with presence of postoperative CME, ERM, and area of preoperative RD.
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Aniseikonia in various retinal disorders
Graefe's Archive for Clinical and Experimental Ophthalmology, 2017Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro OshikaAbstract:Purpose The purpose was to quantify and compare the severity of aniseikonia in patients undergoing vitrectomy for various retinal disorders. Methods We studied 357 patients with retinal disorders including epiretinal membrane (ERM), macular hole (MH), cystoid macular edema with branch / central retinal vein occlusion (BRVO-CME / CRVO-CME), diabetic macular edema (DME), macula-off rhegmatogenous retinal detachment (M-off RD), and macula-on RD (M-on RD) as well as 31 normal controls. The amount of aniseikonia was measured using the New Aniseikonia Test preoperatively and at 6 months postoperatively. Results Of all patients, 59% presented aniseikonia. Preoperative and postoperative mean aniseikonia were 4.0 ± 4.1% and 3.0 ± 3.6%, respectively. In particular, 68% of patients with ERM had Macropsia, and approximately half of MH, RVO-CME, DME, and M-off RD patients had micropsia. Preoperative aniseikonia was significantly severe in ERM than in other disorders. Vitrectomy improved aniseikonia only in MH, while visual acuity was improved in all disorders except CRVO-CME. Conclusion More than half of the patients showed aniseikonia preoperatively. A majority of ERM patients exhibited Macropsia, whereas MH, RVO-CME, DME, and macula-off RD patients presented micropsia. The aniseikonia score was greatest in ERM patients. In most retinal disorders, surgery significantly improved visual acuity, but not aniseikonia.
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Aniseikonia and Foveal Microstructure in Patients with Idiopathic Macular Hole
Ophthalmology, 2016Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Yuki Moriya, Tomoya Murakami, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro OshikaAbstract:Purpose To quantify the severity of aniseikonia in patients undergoing vitrectomy for idiopathic macular hole (MH) and to examine any relationship between aniseikonia and the foveal microstructure. Design Prospective, consecutive, interventional case series. Participants We included 56 eyes of 56 patients who underwent vitrectomy to treat idiopathic MH. Methods We examined visual acuity, aniseikonia using the New Aniseikonia Test, and foveal structure using optical coherence tomography (OCT) before and 3, 6, and 12 months after surgery. Based on OCT images, minimum and base diameters of MH, height of MH, and defect lengths of the external limiting membrane (ELM), ellipsoid zone, and interdigitation zone were assessed. Main Outcome Measures Degree of aniseikonia before and after surgery. Results The mean aniseikonia was −3.2±4.6%, ranging from −15.5% to +5.0%. Of the patients, 55% had micropsia, 7% had Macropsia, and 38% had no aniseikonia. The mean absolute value of aniseikonia improved significantly from 3.8±4.1% before surgery to 1.0±1.5% at 12 months after surgery ( P P P P P Conclusions Approximately half of MH patients had micropsia. Vitrectomy for MH improved aniseikonia. Preoperative aniseikonia was associated with MH size and the defect length of ELM.
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Aniseikonia and Foveal Microstructure after Retinal Detachment Surgery.
Investigative Ophthalmology & Visual Science, 2014Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro OshikaAbstract:PURPOSE. To quantify aniseikonia after successful surgical repair of rhegmatogenous retinal detachment (RD), and to investigate the relationship between the severity of postoperative aniseikonia and retinal microstructures as well as clinical parameters. METHODS. The study included 106 eyes of 106 patients, without any history of ocular disease/ surgery and with less than 2 diopters of anisometropia, who had undergone successful retinal reattachment surgery. Aniseikonia was measured with the New Aniseikonia Test, and foveal microstructure was assessed with spectral-domain optical coherence tomography (OCT) at 6 months postoperatively. RESULTS. Twenty-eight of 106 patients (26%) had micropsia; 17 patients (16%) had Macropsia; and 61 patients (58%) had no aniseikonia. The mean absolute value of aniseikonia was 2.3 6 2.9% (range, � 12.5% to þ12.0%). Of 57 eyes with macula-on RD, 3 had micropsia and 12 had Macropsia. Of 49 eyes with macula-off RD, 25 had micropsia and 5 had Macropsia. Eyes with micropsia mostly exhibited persistent or transient cystoid macular edema, subretinal fluid, hyperreflective or disruption of IS/OS line, while most of the eyes with Macropsia presented epiretinal membrane. Stepwise multiple regression analysis revealed that postoperative bestcorrected visual acuity and the area of RD were significantly relevant to the mean absolute value of aniseikonia. CONCLUSIONS. These results suggested that approximately half of patients with successful repair of RD had aniseikonia. Eyes with macula-off RD tended to show micropsia, while those with macula-on RD mostly presented Macropsia. Micropsia and Macropsia were primarily caused by respective specific abnormal structures at the foveal region.
Takahiro Hiraoka - One of the best experts on this subject based on the ideXlab platform.
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Changes in aniseikonia and influencing-factors following successful macula-off retinal detachment surgery.
Scientific Reports, 2019Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro OshikaAbstract:This study investigated the changes in the severity of aniseikonia after surgery for macula-off retinal detachment (RD), and the relationship between aniseikonia and retinal microstructures. The study included 26 eyes of 26 patients undergoing RD surgery. Visual acuity was measured preoperatively, and at 3, 6, and 12 months postoperatively. Degree of aniseikonia and OCT images were obtained at 3, 6, and 12 months postoperatively. The aniseikonia values (mean ± standard deviation) at 3, 6, and 12 months postoperatively were −5.3 ± 4.2%, −4.4 ± 4.4%, and −3.1 ± 3.2%, respectively. Significant improvement was observed from 3 to 12 months postoperatively (P = 0.001). Twelve months postoperatively, 14 eyes had micropsia, 1 eye had Macropsia, and 11 eyes were free of aniseikonia. Stepwise multiple regression analyses revealed that the severity of aniseikonia at 12 months postoperatively was significantly associated with postoperative development of cystoid macular edema (CME) and epiretinal membrane (ERM), as well as area of preoperative RD. In conclusion, although aniseikonia was gradually relieved after RD surgery during a 1-year follow-up period, approximately half of patients had aniseikonia and almost all of them had micropsia. Aniseikonia was associated with presence of postoperative CME, ERM, and area of preoperative RD.
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Changes in aniseikonia and influencing-factors following successful macula-off retinal detachment surgery.
Scientific Reports, 2019Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro OshikaAbstract:This study investigated the changes in the severity of aniseikonia after surgery for macula-off retinal detachment (RD), and the relationship between aniseikonia and retinal microstructures. The study included 26 eyes of 26 patients undergoing RD surgery. Visual acuity was measured preoperatively, and at 3, 6, and 12 months postoperatively. Degree of aniseikonia and OCT images were obtained at 3, 6, and 12 months postoperatively. The aniseikonia values (mean ± standard deviation) at 3, 6, and 12 months postoperatively were −5.3 ± 4.2%, −4.4 ± 4.4%, and −3.1 ± 3.2%, respectively. Significant improvement was observed from 3 to 12 months postoperatively (P = 0.001). Twelve months postoperatively, 14 eyes had micropsia, 1 eye had Macropsia, and 11 eyes were free of aniseikonia. Stepwise multiple regression analyses revealed that the severity of aniseikonia at 12 months postoperatively was significantly associated with postoperative development of cystoid macular edema (CME) and epiretinal membrane (ERM), as well as area of preoperative RD. In conclusion, although aniseikonia was gradually relieved after RD surgery during a 1-year follow-up period, approximately half of patients had aniseikonia and almost all of them had micropsia. Aniseikonia was associated with presence of postoperative CME, ERM, and area of preoperative RD.
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Aniseikonia in various retinal disorders
Graefe's Archive for Clinical and Experimental Ophthalmology, 2017Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro OshikaAbstract:Purpose The purpose was to quantify and compare the severity of aniseikonia in patients undergoing vitrectomy for various retinal disorders. Methods We studied 357 patients with retinal disorders including epiretinal membrane (ERM), macular hole (MH), cystoid macular edema with branch / central retinal vein occlusion (BRVO-CME / CRVO-CME), diabetic macular edema (DME), macula-off rhegmatogenous retinal detachment (M-off RD), and macula-on RD (M-on RD) as well as 31 normal controls. The amount of aniseikonia was measured using the New Aniseikonia Test preoperatively and at 6 months postoperatively. Results Of all patients, 59% presented aniseikonia. Preoperative and postoperative mean aniseikonia were 4.0 ± 4.1% and 3.0 ± 3.6%, respectively. In particular, 68% of patients with ERM had Macropsia, and approximately half of MH, RVO-CME, DME, and M-off RD patients had micropsia. Preoperative aniseikonia was significantly severe in ERM than in other disorders. Vitrectomy improved aniseikonia only in MH, while visual acuity was improved in all disorders except CRVO-CME. Conclusion More than half of the patients showed aniseikonia preoperatively. A majority of ERM patients exhibited Macropsia, whereas MH, RVO-CME, DME, and macula-off RD patients presented micropsia. The aniseikonia score was greatest in ERM patients. In most retinal disorders, surgery significantly improved visual acuity, but not aniseikonia.
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Aniseikonia and Foveal Microstructure in Patients with Idiopathic Macular Hole
Ophthalmology, 2016Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Yuki Moriya, Tomoya Murakami, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro OshikaAbstract:Purpose To quantify the severity of aniseikonia in patients undergoing vitrectomy for idiopathic macular hole (MH) and to examine any relationship between aniseikonia and the foveal microstructure. Design Prospective, consecutive, interventional case series. Participants We included 56 eyes of 56 patients who underwent vitrectomy to treat idiopathic MH. Methods We examined visual acuity, aniseikonia using the New Aniseikonia Test, and foveal structure using optical coherence tomography (OCT) before and 3, 6, and 12 months after surgery. Based on OCT images, minimum and base diameters of MH, height of MH, and defect lengths of the external limiting membrane (ELM), ellipsoid zone, and interdigitation zone were assessed. Main Outcome Measures Degree of aniseikonia before and after surgery. Results The mean aniseikonia was −3.2±4.6%, ranging from −15.5% to +5.0%. Of the patients, 55% had micropsia, 7% had Macropsia, and 38% had no aniseikonia. The mean absolute value of aniseikonia improved significantly from 3.8±4.1% before surgery to 1.0±1.5% at 12 months after surgery ( P P P P P Conclusions Approximately half of MH patients had micropsia. Vitrectomy for MH improved aniseikonia. Preoperative aniseikonia was associated with MH size and the defect length of ELM.
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Aniseikonia and Foveal Microstructure after Retinal Detachment Surgery.
Investigative Ophthalmology & Visual Science, 2014Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro OshikaAbstract:PURPOSE. To quantify aniseikonia after successful surgical repair of rhegmatogenous retinal detachment (RD), and to investigate the relationship between the severity of postoperative aniseikonia and retinal microstructures as well as clinical parameters. METHODS. The study included 106 eyes of 106 patients, without any history of ocular disease/ surgery and with less than 2 diopters of anisometropia, who had undergone successful retinal reattachment surgery. Aniseikonia was measured with the New Aniseikonia Test, and foveal microstructure was assessed with spectral-domain optical coherence tomography (OCT) at 6 months postoperatively. RESULTS. Twenty-eight of 106 patients (26%) had micropsia; 17 patients (16%) had Macropsia; and 61 patients (58%) had no aniseikonia. The mean absolute value of aniseikonia was 2.3 6 2.9% (range, � 12.5% to þ12.0%). Of 57 eyes with macula-on RD, 3 had micropsia and 12 had Macropsia. Of 49 eyes with macula-off RD, 25 had micropsia and 5 had Macropsia. Eyes with micropsia mostly exhibited persistent or transient cystoid macular edema, subretinal fluid, hyperreflective or disruption of IS/OS line, while most of the eyes with Macropsia presented epiretinal membrane. Stepwise multiple regression analysis revealed that postoperative bestcorrected visual acuity and the area of RD were significantly relevant to the mean absolute value of aniseikonia. CONCLUSIONS. These results suggested that approximately half of patients with successful repair of RD had aniseikonia. Eyes with macula-off RD tended to show micropsia, while those with macula-on RD mostly presented Macropsia. Micropsia and Macropsia were primarily caused by respective specific abnormal structures at the foveal region.
Yoshimi Sugiura - One of the best experts on this subject based on the ideXlab platform.
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Changes in aniseikonia and influencing-factors following successful macula-off retinal detachment surgery.
Scientific Reports, 2019Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro OshikaAbstract:This study investigated the changes in the severity of aniseikonia after surgery for macula-off retinal detachment (RD), and the relationship between aniseikonia and retinal microstructures. The study included 26 eyes of 26 patients undergoing RD surgery. Visual acuity was measured preoperatively, and at 3, 6, and 12 months postoperatively. Degree of aniseikonia and OCT images were obtained at 3, 6, and 12 months postoperatively. The aniseikonia values (mean ± standard deviation) at 3, 6, and 12 months postoperatively were −5.3 ± 4.2%, −4.4 ± 4.4%, and −3.1 ± 3.2%, respectively. Significant improvement was observed from 3 to 12 months postoperatively (P = 0.001). Twelve months postoperatively, 14 eyes had micropsia, 1 eye had Macropsia, and 11 eyes were free of aniseikonia. Stepwise multiple regression analyses revealed that the severity of aniseikonia at 12 months postoperatively was significantly associated with postoperative development of cystoid macular edema (CME) and epiretinal membrane (ERM), as well as area of preoperative RD. In conclusion, although aniseikonia was gradually relieved after RD surgery during a 1-year follow-up period, approximately half of patients had aniseikonia and almost all of them had micropsia. Aniseikonia was associated with presence of postoperative CME, ERM, and area of preoperative RD.
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Changes in aniseikonia and influencing-factors following successful macula-off retinal detachment surgery.
Scientific Reports, 2019Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro OshikaAbstract:This study investigated the changes in the severity of aniseikonia after surgery for macula-off retinal detachment (RD), and the relationship between aniseikonia and retinal microstructures. The study included 26 eyes of 26 patients undergoing RD surgery. Visual acuity was measured preoperatively, and at 3, 6, and 12 months postoperatively. Degree of aniseikonia and OCT images were obtained at 3, 6, and 12 months postoperatively. The aniseikonia values (mean ± standard deviation) at 3, 6, and 12 months postoperatively were −5.3 ± 4.2%, −4.4 ± 4.4%, and −3.1 ± 3.2%, respectively. Significant improvement was observed from 3 to 12 months postoperatively (P = 0.001). Twelve months postoperatively, 14 eyes had micropsia, 1 eye had Macropsia, and 11 eyes were free of aniseikonia. Stepwise multiple regression analyses revealed that the severity of aniseikonia at 12 months postoperatively was significantly associated with postoperative development of cystoid macular edema (CME) and epiretinal membrane (ERM), as well as area of preoperative RD. In conclusion, although aniseikonia was gradually relieved after RD surgery during a 1-year follow-up period, approximately half of patients had aniseikonia and almost all of them had micropsia. Aniseikonia was associated with presence of postoperative CME, ERM, and area of preoperative RD.
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Aniseikonia in various retinal disorders
Graefe's Archive for Clinical and Experimental Ophthalmology, 2017Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro OshikaAbstract:Purpose The purpose was to quantify and compare the severity of aniseikonia in patients undergoing vitrectomy for various retinal disorders. Methods We studied 357 patients with retinal disorders including epiretinal membrane (ERM), macular hole (MH), cystoid macular edema with branch / central retinal vein occlusion (BRVO-CME / CRVO-CME), diabetic macular edema (DME), macula-off rhegmatogenous retinal detachment (M-off RD), and macula-on RD (M-on RD) as well as 31 normal controls. The amount of aniseikonia was measured using the New Aniseikonia Test preoperatively and at 6 months postoperatively. Results Of all patients, 59% presented aniseikonia. Preoperative and postoperative mean aniseikonia were 4.0 ± 4.1% and 3.0 ± 3.6%, respectively. In particular, 68% of patients with ERM had Macropsia, and approximately half of MH, RVO-CME, DME, and M-off RD patients had micropsia. Preoperative aniseikonia was significantly severe in ERM than in other disorders. Vitrectomy improved aniseikonia only in MH, while visual acuity was improved in all disorders except CRVO-CME. Conclusion More than half of the patients showed aniseikonia preoperatively. A majority of ERM patients exhibited Macropsia, whereas MH, RVO-CME, DME, and macula-off RD patients presented micropsia. The aniseikonia score was greatest in ERM patients. In most retinal disorders, surgery significantly improved visual acuity, but not aniseikonia.
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Aniseikonia and Foveal Microstructure in Patients with Idiopathic Macular Hole
Ophthalmology, 2016Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Yuki Moriya, Tomoya Murakami, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro OshikaAbstract:Purpose To quantify the severity of aniseikonia in patients undergoing vitrectomy for idiopathic macular hole (MH) and to examine any relationship between aniseikonia and the foveal microstructure. Design Prospective, consecutive, interventional case series. Participants We included 56 eyes of 56 patients who underwent vitrectomy to treat idiopathic MH. Methods We examined visual acuity, aniseikonia using the New Aniseikonia Test, and foveal structure using optical coherence tomography (OCT) before and 3, 6, and 12 months after surgery. Based on OCT images, minimum and base diameters of MH, height of MH, and defect lengths of the external limiting membrane (ELM), ellipsoid zone, and interdigitation zone were assessed. Main Outcome Measures Degree of aniseikonia before and after surgery. Results The mean aniseikonia was −3.2±4.6%, ranging from −15.5% to +5.0%. Of the patients, 55% had micropsia, 7% had Macropsia, and 38% had no aniseikonia. The mean absolute value of aniseikonia improved significantly from 3.8±4.1% before surgery to 1.0±1.5% at 12 months after surgery ( P P P P P Conclusions Approximately half of MH patients had micropsia. Vitrectomy for MH improved aniseikonia. Preoperative aniseikonia was associated with MH size and the defect length of ELM.
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Aniseikonia and Foveal Microstructure after Retinal Detachment Surgery.
Investigative Ophthalmology & Visual Science, 2014Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro OshikaAbstract:PURPOSE. To quantify aniseikonia after successful surgical repair of rhegmatogenous retinal detachment (RD), and to investigate the relationship between the severity of postoperative aniseikonia and retinal microstructures as well as clinical parameters. METHODS. The study included 106 eyes of 106 patients, without any history of ocular disease/ surgery and with less than 2 diopters of anisometropia, who had undergone successful retinal reattachment surgery. Aniseikonia was measured with the New Aniseikonia Test, and foveal microstructure was assessed with spectral-domain optical coherence tomography (OCT) at 6 months postoperatively. RESULTS. Twenty-eight of 106 patients (26%) had micropsia; 17 patients (16%) had Macropsia; and 61 patients (58%) had no aniseikonia. The mean absolute value of aniseikonia was 2.3 6 2.9% (range, � 12.5% to þ12.0%). Of 57 eyes with macula-on RD, 3 had micropsia and 12 had Macropsia. Of 49 eyes with macula-off RD, 25 had micropsia and 5 had Macropsia. Eyes with micropsia mostly exhibited persistent or transient cystoid macular edema, subretinal fluid, hyperreflective or disruption of IS/OS line, while most of the eyes with Macropsia presented epiretinal membrane. Stepwise multiple regression analysis revealed that postoperative bestcorrected visual acuity and the area of RD were significantly relevant to the mean absolute value of aniseikonia. CONCLUSIONS. These results suggested that approximately half of patients with successful repair of RD had aniseikonia. Eyes with macula-off RD tended to show micropsia, while those with macula-on RD mostly presented Macropsia. Micropsia and Macropsia were primarily caused by respective specific abnormal structures at the foveal region.
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Changes in aniseikonia and influencing-factors following successful macula-off retinal detachment surgery.
Scientific Reports, 2019Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro OshikaAbstract:This study investigated the changes in the severity of aniseikonia after surgery for macula-off retinal detachment (RD), and the relationship between aniseikonia and retinal microstructures. The study included 26 eyes of 26 patients undergoing RD surgery. Visual acuity was measured preoperatively, and at 3, 6, and 12 months postoperatively. Degree of aniseikonia and OCT images were obtained at 3, 6, and 12 months postoperatively. The aniseikonia values (mean ± standard deviation) at 3, 6, and 12 months postoperatively were −5.3 ± 4.2%, −4.4 ± 4.4%, and −3.1 ± 3.2%, respectively. Significant improvement was observed from 3 to 12 months postoperatively (P = 0.001). Twelve months postoperatively, 14 eyes had micropsia, 1 eye had Macropsia, and 11 eyes were free of aniseikonia. Stepwise multiple regression analyses revealed that the severity of aniseikonia at 12 months postoperatively was significantly associated with postoperative development of cystoid macular edema (CME) and epiretinal membrane (ERM), as well as area of preoperative RD. In conclusion, although aniseikonia was gradually relieved after RD surgery during a 1-year follow-up period, approximately half of patients had aniseikonia and almost all of them had micropsia. Aniseikonia was associated with presence of postoperative CME, ERM, and area of preoperative RD.
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Changes in aniseikonia and influencing-factors following successful macula-off retinal detachment surgery.
Scientific Reports, 2019Co-Authors: Tomoya Murakami, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Fumiki Okamoto, Tetsuro OshikaAbstract:This study investigated the changes in the severity of aniseikonia after surgery for macula-off retinal detachment (RD), and the relationship between aniseikonia and retinal microstructures. The study included 26 eyes of 26 patients undergoing RD surgery. Visual acuity was measured preoperatively, and at 3, 6, and 12 months postoperatively. Degree of aniseikonia and OCT images were obtained at 3, 6, and 12 months postoperatively. The aniseikonia values (mean ± standard deviation) at 3, 6, and 12 months postoperatively were −5.3 ± 4.2%, −4.4 ± 4.4%, and −3.1 ± 3.2%, respectively. Significant improvement was observed from 3 to 12 months postoperatively (P = 0.001). Twelve months postoperatively, 14 eyes had micropsia, 1 eye had Macropsia, and 11 eyes were free of aniseikonia. Stepwise multiple regression analyses revealed that the severity of aniseikonia at 12 months postoperatively was significantly associated with postoperative development of cystoid macular edema (CME) and epiretinal membrane (ERM), as well as area of preoperative RD. In conclusion, although aniseikonia was gradually relieved after RD surgery during a 1-year follow-up period, approximately half of patients had aniseikonia and almost all of them had micropsia. Aniseikonia was associated with presence of postoperative CME, ERM, and area of preoperative RD.
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Aniseikonia in various retinal disorders
Graefe's Archive for Clinical and Experimental Ophthalmology, 2017Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro OshikaAbstract:Purpose The purpose was to quantify and compare the severity of aniseikonia in patients undergoing vitrectomy for various retinal disorders. Methods We studied 357 patients with retinal disorders including epiretinal membrane (ERM), macular hole (MH), cystoid macular edema with branch / central retinal vein occlusion (BRVO-CME / CRVO-CME), diabetic macular edema (DME), macula-off rhegmatogenous retinal detachment (M-off RD), and macula-on RD (M-on RD) as well as 31 normal controls. The amount of aniseikonia was measured using the New Aniseikonia Test preoperatively and at 6 months postoperatively. Results Of all patients, 59% presented aniseikonia. Preoperative and postoperative mean aniseikonia were 4.0 ± 4.1% and 3.0 ± 3.6%, respectively. In particular, 68% of patients with ERM had Macropsia, and approximately half of MH, RVO-CME, DME, and M-off RD patients had micropsia. Preoperative aniseikonia was significantly severe in ERM than in other disorders. Vitrectomy improved aniseikonia only in MH, while visual acuity was improved in all disorders except CRVO-CME. Conclusion More than half of the patients showed aniseikonia preoperatively. A majority of ERM patients exhibited Macropsia, whereas MH, RVO-CME, DME, and macula-off RD patients presented micropsia. The aniseikonia score was greatest in ERM patients. In most retinal disorders, surgery significantly improved visual acuity, but not aniseikonia.
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Aniseikonia and Foveal Microstructure in Patients with Idiopathic Macular Hole
Ophthalmology, 2016Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Yuki Moriya, Tomoya Murakami, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro OshikaAbstract:Purpose To quantify the severity of aniseikonia in patients undergoing vitrectomy for idiopathic macular hole (MH) and to examine any relationship between aniseikonia and the foveal microstructure. Design Prospective, consecutive, interventional case series. Participants We included 56 eyes of 56 patients who underwent vitrectomy to treat idiopathic MH. Methods We examined visual acuity, aniseikonia using the New Aniseikonia Test, and foveal structure using optical coherence tomography (OCT) before and 3, 6, and 12 months after surgery. Based on OCT images, minimum and base diameters of MH, height of MH, and defect lengths of the external limiting membrane (ELM), ellipsoid zone, and interdigitation zone were assessed. Main Outcome Measures Degree of aniseikonia before and after surgery. Results The mean aniseikonia was −3.2±4.6%, ranging from −15.5% to +5.0%. Of the patients, 55% had micropsia, 7% had Macropsia, and 38% had no aniseikonia. The mean absolute value of aniseikonia improved significantly from 3.8±4.1% before surgery to 1.0±1.5% at 12 months after surgery ( P P P P P Conclusions Approximately half of MH patients had micropsia. Vitrectomy for MH improved aniseikonia. Preoperative aniseikonia was associated with MH size and the defect length of ELM.
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Aniseikonia and Foveal Microstructure after Retinal Detachment Surgery.
Investigative Ophthalmology & Visual Science, 2014Co-Authors: Fumiki Okamoto, Yoshimi Sugiura, Takahiro Hiraoka, Yoshifumi Okamoto, Tetsuro OshikaAbstract:PURPOSE. To quantify aniseikonia after successful surgical repair of rhegmatogenous retinal detachment (RD), and to investigate the relationship between the severity of postoperative aniseikonia and retinal microstructures as well as clinical parameters. METHODS. The study included 106 eyes of 106 patients, without any history of ocular disease/ surgery and with less than 2 diopters of anisometropia, who had undergone successful retinal reattachment surgery. Aniseikonia was measured with the New Aniseikonia Test, and foveal microstructure was assessed with spectral-domain optical coherence tomography (OCT) at 6 months postoperatively. RESULTS. Twenty-eight of 106 patients (26%) had micropsia; 17 patients (16%) had Macropsia; and 61 patients (58%) had no aniseikonia. The mean absolute value of aniseikonia was 2.3 6 2.9% (range, � 12.5% to þ12.0%). Of 57 eyes with macula-on RD, 3 had micropsia and 12 had Macropsia. Of 49 eyes with macula-off RD, 25 had micropsia and 5 had Macropsia. Eyes with micropsia mostly exhibited persistent or transient cystoid macular edema, subretinal fluid, hyperreflective or disruption of IS/OS line, while most of the eyes with Macropsia presented epiretinal membrane. Stepwise multiple regression analysis revealed that postoperative bestcorrected visual acuity and the area of RD were significantly relevant to the mean absolute value of aniseikonia. CONCLUSIONS. These results suggested that approximately half of patients with successful repair of RD had aniseikonia. Eyes with macula-off RD tended to show micropsia, while those with macula-on RD mostly presented Macropsia. Micropsia and Macropsia were primarily caused by respective specific abnormal structures at the foveal region.
