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Wei Shi - One of the best experts on this subject based on the ideXlab platform.
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outcomes of sulfur hexafluoride sf6 versus perfluoropropane c3f8 gas tamponade for Macular Hole surgery
Retina-the Journal of Retinal and Vitreous Diseases, 2008Co-Authors: Sung Soo Kim, William E Smiddy, William J Feuer, Wei ShiAbstract:Purpose: To compare outcomes of Macular Hole surgery using sulfur hexafluoride (SF6) gas versus perfluoropropane (C3F8) gas for idiopathic Macular Hole repair. Design: Retrospective, interventional, comparative cohort study. Methods: Institutional clinical practice. A consecutive group of patients undergoing Macular Hole surgery with SF6 group (38 eyes of 38 patients) and a nonconsecutive, contemporaneous, comparison group with C3F8 was used (41 eyes of 39 patients). Vitrectomy for Macular Hole surgery using either of two different gases for internal tamponade. Best corrected logarithm of minimal angle resolution visual acuity, anatomic closure, reoperations, development of cataract, and complications such as retinal detachment. Result: The Macular Hole closure rate was similar in both groups [34/38 (90%) with SF6 gas versus 37/41 (91%) with C3F8 gas, P = 0.91]. At 6 months after Macular Hole surgery, best-corrected visual acuity was improved compare with baseline visual acuity by a mean of 0.32 logarithm of minimal angle resolution in the SF6 group (P = 0.045) and 0.52 logarithm of minimal angle resolution in the C3F8 group (P Conclusion: Macular Hole surgery using SF6 gas yields similar results as with C3F8 gas and may be a good option.
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outcomes of sulfur hexafluoride sf6 versus perfluoropropane c3f8 gas tamponade for Macular Hole surgery
Retina-the Journal of Retinal and Vitreous Diseases, 2008Co-Authors: Sung Soo Kim, William E Smiddy, William J Feuer, Wei ShiAbstract:PURPOSE: To compare outcomes of Macular Hole surgery using sulfur hexafluoride (SF6) gas versus perfluoropropane (C3F8) gas for idiopathic Macular Hole repair. DESIGN: Retrospective, interventional, comparative cohort study. METHODS: Institutional clinical practice. A consecutive group of patients undergoing Macular Hole surgery with SF6 group (38 eyes of 38 patients) and a nonconsecutive, contemporaneous, comparison group with C3F8 was used (41 eyes of 39 patients). Vitrectomy for Macular Hole surgery using either of two different gases for internal tamponade. Best corrected logarithm of minimal angle resolution visual acuity, anatomic closure, reoperations, development of cataract, and complications such as retinal detachment. RESULT: The Macular Hole closure rate was similar in both groups [34/38 (90%) with SF6 gas versus 37/41 (91%) with C3F8 gas, P = 0.91]. At 6 months after Macular Hole surgery, best-corrected visual acuity was improved compare with baseline visual acuity by a mean of 0.32 logarithm of minimal angle resolution in the SF6 group (P = 0.045) and 0.52 logarithm of minimal angle resolution in the C3F8 group (P < 0.001). Development of vision-impairing cataract in phakic eyes was not different, but the myopic shift was greater in the C3F8 group (P = 0.016). CONCLUSION: Macular Hole surgery using SF6 gas yields similar results as with C3F8 gas and may be a good option.
Dennis S C Lam - One of the best experts on this subject based on the ideXlab platform.
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pars plana vitrectomy and perfluoropropane c3f8 tamponade for retinal detachment due to myopic Macular Hole a prognostic factor analysis
American Journal of Ophthalmology, 2006Co-Authors: Robert F Lam, Wico W Lai, Benson T O Cheung, Can Y F Yuen, T H Wong, Mahesh P Shanmugam, Dennis S C LamAbstract:Purpose To determine the prognostic factors associated with anatomical success in the treatment of retinal detachment (RD) due to myopic Macular Hole by pars plana vitrectomy (PPV) and perfluoropropane (C 3 F 8 ) gas tamponade. Design Retrospective, interventional, comparative case series. Methods In an institutional setting, 57 eyes with myopic Macular Hole RDs treated by PPV and C 3 F 8 tamponade, with or without concomitant internal limiting membrane (ILM) peeling, endolaser photocoagulation, and/or phacoemulsification, were analyzed. Outcome measures were anatomical success, defined as closure of Macular Hole with reattachment of the surrounding retina, and postoperative best-corrected visual acuity (BCVA). Results The mean postoperative follow-up was 26.9 ± 16.5 months. The anatomical success rate after primary PPV and C 3 F 8 tamponade was 63.2%. Regression analysis showed that shorter axial lengths (odds ratio [OR] = 6.73, 95% confidence interval [95% CI] 1.86 to 12.22, P = .010), concomitant ILM peeling (OR 1.59, 95% CI 1.14 to 2.38, P = .013), and shorter duration of Macular Hole RD (OR 0.81, 95% CI 0.67 to 0.98, P = .033) were associated with a higher anatomical success. The mean pre- and postoperative BCVAs were 1.430 ± 0.273 (range, 0.523 to 1.700) and 1.403 ± 0.271 (range, 0.699 to 1.800) logarithm of minimal angle of resolution units, respectively. The postoperative BCVA was significantly better in eyes with Macular Hole closure than in eyes without ( P = .021). Conclusions Axial length, concomitant ILM peeling, and duration were important prognostic factors for PPV and C 3 F 8 tamponade in the treatment of myopic Macular Hole RDs.
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indocyanine green staining and removal of internal limiting membrane in Macular Hole surgery histology and outcome
American Journal of Ophthalmology, 2001Co-Authors: Alvin K H Kwok, Chi Pui Pang, Timothy Y Y Lai, Gary Hinfai Yam, Nongnart R Chan, Dennis S C LamAbstract:Abstract PURPOSE: To report the surgical technique, outcome, and histologic findings involving indocyanine green staining and removal of internal limiting membrane in primary Macular Hole surgery. METHODS: Prospectively, consecutive patients with idiopathic Macular Hole or myopic Macular Hole with retinal detachment were recruited. After pars plana vitrectomy and epiretinal membrane removal, the internal limiting membrane was stained and removed. The specimens were stained using hematoxylin and eosin and periodic acid-Schiff. Immunohistochemical staining was also performed for glial fibrillary acidic protein, vimentin, type I and type IV collagen, and actin. RESULTS: Among 10 patients (10 eyes) in the study, nine eyes had stage 3 or 4 Macular Hole. Four of them had chronic Macular Hole. The tenth patient had retinal detachment resulting from a myopic Macular Hole. Postoperatively, all cases had closure of Macular Hole without an elevated edge and the retina was attached. Seven patients had improvement of 2 or more Snellen lines, whereas visual acuity remained the same for the other three patients. In six eyes in which complete histologic examinations were feasible, internal limiting membrane was confirmed and two eyes also had a small amount of epiretinal membrane. Myofibrocytes in internal limiting membrane, either scattered or as a single layer, were found in three cases. CONCLUSIONS: Removal of indocyanine green-stained internal limiting membrane around idiopathic Macular Hole or myopic Macular Hole with retinal detachment is confirmed with histology and may contribute to Macular Hole closure and retinal reattachment.
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endolaser around Macular Hole in the management of associated retinal detachment in highly myopic eyes
Retina-the Journal of Retinal and Vitreous Diseases, 2000Co-Authors: Alvin K H Kwok, Lulu L Cheng, Lingam Gopal, Tarun Sharma, Dennis S C LamAbstract:PURPOSE To analyze the role of endolaser around Macular Hole in managing associated retinal detachment in patients with high myopia. METHODS Review of medical records of 25 consecutive eyes of 25 patients with at least 5.00 diopters of myopia who underwent primary pars plana vitrectomy and fluid-gas exchange. In the first half of the study period, one row of contiguous argon green endolaser was routinely applied over the retinal edge of the Macular Hole (EL group). In the second half of the study period, endolaser was not applied around any Macular Hole (NEL group). Demographic information, intraoperative and postoperative complications, and final visual acuities and retinal reattachment rates were studied. RESULTS The mean (+/-SD) refractive error was -11.8 +/- -3.5 diopters (D) for the EL group and -11.6 +/- -5.4 D for the NEL group. The mean axial length was 29.0 +/- 1.8 mm for the EL group and 28.3 +/- 1.7 mm for the NEL group. The primary anatomic success was 62.5% (10/16) and 77.8% (7/9) in the EL and NEL groups, respectively. No statistically significant difference was found in preoperative, postoperative, or change in best-corrected visual acuities between the two groups. CONCLUSION Endolaser around the Macular Hole after pars plana vitrectomy and internal gas tamponade may not affect the anatomic or visual outcome in primary retinal detachment secondary to a highly myopic Macular Hole.
Sung Soo Kim - One of the best experts on this subject based on the ideXlab platform.
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outcomes of sulfur hexafluoride sf6 versus perfluoropropane c3f8 gas tamponade for Macular Hole surgery
Retina-the Journal of Retinal and Vitreous Diseases, 2008Co-Authors: Sung Soo Kim, William E Smiddy, William J Feuer, Wei ShiAbstract:Purpose: To compare outcomes of Macular Hole surgery using sulfur hexafluoride (SF6) gas versus perfluoropropane (C3F8) gas for idiopathic Macular Hole repair. Design: Retrospective, interventional, comparative cohort study. Methods: Institutional clinical practice. A consecutive group of patients undergoing Macular Hole surgery with SF6 group (38 eyes of 38 patients) and a nonconsecutive, contemporaneous, comparison group with C3F8 was used (41 eyes of 39 patients). Vitrectomy for Macular Hole surgery using either of two different gases for internal tamponade. Best corrected logarithm of minimal angle resolution visual acuity, anatomic closure, reoperations, development of cataract, and complications such as retinal detachment. Result: The Macular Hole closure rate was similar in both groups [34/38 (90%) with SF6 gas versus 37/41 (91%) with C3F8 gas, P = 0.91]. At 6 months after Macular Hole surgery, best-corrected visual acuity was improved compare with baseline visual acuity by a mean of 0.32 logarithm of minimal angle resolution in the SF6 group (P = 0.045) and 0.52 logarithm of minimal angle resolution in the C3F8 group (P Conclusion: Macular Hole surgery using SF6 gas yields similar results as with C3F8 gas and may be a good option.
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outcomes of sulfur hexafluoride sf6 versus perfluoropropane c3f8 gas tamponade for Macular Hole surgery
Retina-the Journal of Retinal and Vitreous Diseases, 2008Co-Authors: Sung Soo Kim, William E Smiddy, William J Feuer, Wei ShiAbstract:PURPOSE: To compare outcomes of Macular Hole surgery using sulfur hexafluoride (SF6) gas versus perfluoropropane (C3F8) gas for idiopathic Macular Hole repair. DESIGN: Retrospective, interventional, comparative cohort study. METHODS: Institutional clinical practice. A consecutive group of patients undergoing Macular Hole surgery with SF6 group (38 eyes of 38 patients) and a nonconsecutive, contemporaneous, comparison group with C3F8 was used (41 eyes of 39 patients). Vitrectomy for Macular Hole surgery using either of two different gases for internal tamponade. Best corrected logarithm of minimal angle resolution visual acuity, anatomic closure, reoperations, development of cataract, and complications such as retinal detachment. RESULT: The Macular Hole closure rate was similar in both groups [34/38 (90%) with SF6 gas versus 37/41 (91%) with C3F8 gas, P = 0.91]. At 6 months after Macular Hole surgery, best-corrected visual acuity was improved compare with baseline visual acuity by a mean of 0.32 logarithm of minimal angle resolution in the SF6 group (P = 0.045) and 0.52 logarithm of minimal angle resolution in the C3F8 group (P < 0.001). Development of vision-impairing cataract in phakic eyes was not different, but the myopic shift was greater in the C3F8 group (P = 0.016). CONCLUSION: Macular Hole surgery using SF6 gas yields similar results as with C3F8 gas and may be a good option.
William E Smiddy - One of the best experts on this subject based on the ideXlab platform.
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rates of reoperation and retinal detachment after Macular Hole surgery
Ophthalmology, 2016Co-Authors: Kamyar Vaziri, William E Smiddy, Stephen G Schwartz, Krishna S Kishor, Jorge A Fortun, Andrew A Moshfeghi, Harry W. FlynnAbstract:Purpose To evaluate rates of reoperation and retinal detachment (RD) after Macular Hole surgery. Design Retrospective cross-sectional study. Participants Patients in the insurance claim–based MarketScan databases from 2007 through 2013 with a record of Macular Hole surgery. Methods Patients with Macular Hole surgery were identified. Cases of definite (the same eye was coded both times) and presumed (the eye laterality was not coded) Macular Hole reoperations within 2, 3, and 12 months were queried. In addition, cases of postoperative RD within 2, 3, and 12 months were captured. Main Outcome Measures Rates of Macular Hole reoperation and postoperative RD, including subgroup analysis based on presence or absence of internal limiting membrane (ILM) peeling. Results Records of 23465 Macular Hole surgeries among 20 764 patients were analyzed. Among presumed reoperations, the rates of reoperation were 4.3% (4.1% after ILM peeling and 5.0% after no ILM peeling; P = 0.01) within 2 months of surgery, 5.5% (5.3% after ILM peeling and 6.2% after no ILM peeling; P = 0.03) within 3 months of surgery, and 9.5% (9.0% after ILM peeling and 11.0% after no ILM peeling; P = 0.01) within 12 months of surgery. The rates for definite reoperations were 1.3% (1.2% after ILM peeling and 1.8% after no ILM peeling; P = 0.04) at 2 months, 1.7% (1.6% after ILM peeling and 2.5% after no ILM peeling; P = 0.004) at 3 months, and 4.1% (3.3% after ILM peeling and 7.5% after no ILM peeling; P P = 0.007), 3 months (2.8% vs. 2.1%; P = 0.004), and 12 months (4.7% vs. 3.3%; P Conclusions In this sample, reoperations for Macular Hole were performed at low rates. Internal limiting membrane peeling was associated with lower rates of reoperation and RD.
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outcomes of sulfur hexafluoride sf6 versus perfluoropropane c3f8 gas tamponade for Macular Hole surgery
Retina-the Journal of Retinal and Vitreous Diseases, 2008Co-Authors: Sung Soo Kim, William E Smiddy, William J Feuer, Wei ShiAbstract:Purpose: To compare outcomes of Macular Hole surgery using sulfur hexafluoride (SF6) gas versus perfluoropropane (C3F8) gas for idiopathic Macular Hole repair. Design: Retrospective, interventional, comparative cohort study. Methods: Institutional clinical practice. A consecutive group of patients undergoing Macular Hole surgery with SF6 group (38 eyes of 38 patients) and a nonconsecutive, contemporaneous, comparison group with C3F8 was used (41 eyes of 39 patients). Vitrectomy for Macular Hole surgery using either of two different gases for internal tamponade. Best corrected logarithm of minimal angle resolution visual acuity, anatomic closure, reoperations, development of cataract, and complications such as retinal detachment. Result: The Macular Hole closure rate was similar in both groups [34/38 (90%) with SF6 gas versus 37/41 (91%) with C3F8 gas, P = 0.91]. At 6 months after Macular Hole surgery, best-corrected visual acuity was improved compare with baseline visual acuity by a mean of 0.32 logarithm of minimal angle resolution in the SF6 group (P = 0.045) and 0.52 logarithm of minimal angle resolution in the C3F8 group (P Conclusion: Macular Hole surgery using SF6 gas yields similar results as with C3F8 gas and may be a good option.
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outcomes of sulfur hexafluoride sf6 versus perfluoropropane c3f8 gas tamponade for Macular Hole surgery
Retina-the Journal of Retinal and Vitreous Diseases, 2008Co-Authors: Sung Soo Kim, William E Smiddy, William J Feuer, Wei ShiAbstract:PURPOSE: To compare outcomes of Macular Hole surgery using sulfur hexafluoride (SF6) gas versus perfluoropropane (C3F8) gas for idiopathic Macular Hole repair. DESIGN: Retrospective, interventional, comparative cohort study. METHODS: Institutional clinical practice. A consecutive group of patients undergoing Macular Hole surgery with SF6 group (38 eyes of 38 patients) and a nonconsecutive, contemporaneous, comparison group with C3F8 was used (41 eyes of 39 patients). Vitrectomy for Macular Hole surgery using either of two different gases for internal tamponade. Best corrected logarithm of minimal angle resolution visual acuity, anatomic closure, reoperations, development of cataract, and complications such as retinal detachment. RESULT: The Macular Hole closure rate was similar in both groups [34/38 (90%) with SF6 gas versus 37/41 (91%) with C3F8 gas, P = 0.91]. At 6 months after Macular Hole surgery, best-corrected visual acuity was improved compare with baseline visual acuity by a mean of 0.32 logarithm of minimal angle resolution in the SF6 group (P = 0.045) and 0.52 logarithm of minimal angle resolution in the C3F8 group (P < 0.001). Development of vision-impairing cataract in phakic eyes was not different, but the myopic shift was greater in the C3F8 group (P = 0.016). CONCLUSION: Macular Hole surgery using SF6 gas yields similar results as with C3F8 gas and may be a good option.
William J Feuer - One of the best experts on this subject based on the ideXlab platform.
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outcomes of sulfur hexafluoride sf6 versus perfluoropropane c3f8 gas tamponade for Macular Hole surgery
Retina-the Journal of Retinal and Vitreous Diseases, 2008Co-Authors: Sung Soo Kim, William E Smiddy, William J Feuer, Wei ShiAbstract:Purpose: To compare outcomes of Macular Hole surgery using sulfur hexafluoride (SF6) gas versus perfluoropropane (C3F8) gas for idiopathic Macular Hole repair. Design: Retrospective, interventional, comparative cohort study. Methods: Institutional clinical practice. A consecutive group of patients undergoing Macular Hole surgery with SF6 group (38 eyes of 38 patients) and a nonconsecutive, contemporaneous, comparison group with C3F8 was used (41 eyes of 39 patients). Vitrectomy for Macular Hole surgery using either of two different gases for internal tamponade. Best corrected logarithm of minimal angle resolution visual acuity, anatomic closure, reoperations, development of cataract, and complications such as retinal detachment. Result: The Macular Hole closure rate was similar in both groups [34/38 (90%) with SF6 gas versus 37/41 (91%) with C3F8 gas, P = 0.91]. At 6 months after Macular Hole surgery, best-corrected visual acuity was improved compare with baseline visual acuity by a mean of 0.32 logarithm of minimal angle resolution in the SF6 group (P = 0.045) and 0.52 logarithm of minimal angle resolution in the C3F8 group (P Conclusion: Macular Hole surgery using SF6 gas yields similar results as with C3F8 gas and may be a good option.
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outcomes of sulfur hexafluoride sf6 versus perfluoropropane c3f8 gas tamponade for Macular Hole surgery
Retina-the Journal of Retinal and Vitreous Diseases, 2008Co-Authors: Sung Soo Kim, William E Smiddy, William J Feuer, Wei ShiAbstract:PURPOSE: To compare outcomes of Macular Hole surgery using sulfur hexafluoride (SF6) gas versus perfluoropropane (C3F8) gas for idiopathic Macular Hole repair. DESIGN: Retrospective, interventional, comparative cohort study. METHODS: Institutional clinical practice. A consecutive group of patients undergoing Macular Hole surgery with SF6 group (38 eyes of 38 patients) and a nonconsecutive, contemporaneous, comparison group with C3F8 was used (41 eyes of 39 patients). Vitrectomy for Macular Hole surgery using either of two different gases for internal tamponade. Best corrected logarithm of minimal angle resolution visual acuity, anatomic closure, reoperations, development of cataract, and complications such as retinal detachment. RESULT: The Macular Hole closure rate was similar in both groups [34/38 (90%) with SF6 gas versus 37/41 (91%) with C3F8 gas, P = 0.91]. At 6 months after Macular Hole surgery, best-corrected visual acuity was improved compare with baseline visual acuity by a mean of 0.32 logarithm of minimal angle resolution in the SF6 group (P = 0.045) and 0.52 logarithm of minimal angle resolution in the C3F8 group (P < 0.001). Development of vision-impairing cataract in phakic eyes was not different, but the myopic shift was greater in the C3F8 group (P = 0.016). CONCLUSION: Macular Hole surgery using SF6 gas yields similar results as with C3F8 gas and may be a good option.
