The Experts below are selected from a list of 48 Experts worldwide ranked by ideXlab platform
Joseph Sherma - One of the best experts on this subject based on the ideXlab platform.
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development of quantitative hptlc densitometry methods for the analysis of amiodarone hcl carvedilol doxylamine succinate Magnesium Salicylate metoprolol succinate nebivolol hcl and salicylamide using a model process developed earlier for the transfe
Acta Chromatographica, 2018Co-Authors: K Nguyen, Joseph ShermaAbstract:A model process, previously developed in a series of studies, allows for the transfer of thin-layer chromatography (TLC) methods for qualitative screening of counterfeit drug products published in the Global Pharma Health Fund (GPHF) Minilab manual and US Food and Drug Administration (FDA) Compendium of Unofficial Methods for Screening of Pharmaceuticals by TLC to quantitative high-performance TLC (HPTLC)–densitometry methods. This article describes HPTLC–densitometry methods developed and validated according to this model process for pharmaceutical products of amiodarone HCl, carvedilol, doxylamine succinate, Magnesium Salicylate, metoprolol succinate, nebivolol HCl, and salicylamide, for which qualitative screening methods have not been published in the Minilab manual or FDA Compendium. These methods use relatively inexpensive and nontoxic “green solvents” for sample and standard solution and mobile phase preparation, Merck Premium Purity silica gel 60 F254 plates, automated standard and sample solution...
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Development of Quantitative HPTLC–Densitometry Methods for the Analysis of Amiodarone HCl, Carvedilol, Doxylamine Succinate, Magnesium Salicylate, Metoprolol Succinate, Nebivolol HCl, and Salicylamide Using a Model Process Developed Earlier for the T
Acta Chromatographica, 2018Co-Authors: K Nguyen, Joseph ShermaAbstract:A model process, previously developed in a series of studies, allows for the transfer of thin-layer chromatography (TLC) methods for qualitative screening of counterfeit drug products published in the Global Pharma Health Fund (GPHF) Minilab manual and US Food and Drug Administration (FDA) Compendium of Unofficial Methods for Screening of Pharmaceuticals by TLC to quantitative high-performance TLC (HPTLC)–densitometry methods. This article describes HPTLC–densitometry methods developed and validated according to this model process for pharmaceutical products of amiodarone HCl, carvedilol, doxylamine succinate, Magnesium Salicylate, metoprolol succinate, nebivolol HCl, and salicylamide, for which qualitative screening methods have not been published in the Minilab manual or FDA Compendium. These methods use relatively inexpensive and nontoxic “green solvents” for sample and standard solution and mobile phase preparation, Merck Premium Purity silica gel 60 F254 plates, automated standard and sample solution...
K Nguyen - One of the best experts on this subject based on the ideXlab platform.
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development of quantitative hptlc densitometry methods for the analysis of amiodarone hcl carvedilol doxylamine succinate Magnesium Salicylate metoprolol succinate nebivolol hcl and salicylamide using a model process developed earlier for the transfe
Acta Chromatographica, 2018Co-Authors: K Nguyen, Joseph ShermaAbstract:A model process, previously developed in a series of studies, allows for the transfer of thin-layer chromatography (TLC) methods for qualitative screening of counterfeit drug products published in the Global Pharma Health Fund (GPHF) Minilab manual and US Food and Drug Administration (FDA) Compendium of Unofficial Methods for Screening of Pharmaceuticals by TLC to quantitative high-performance TLC (HPTLC)–densitometry methods. This article describes HPTLC–densitometry methods developed and validated according to this model process for pharmaceutical products of amiodarone HCl, carvedilol, doxylamine succinate, Magnesium Salicylate, metoprolol succinate, nebivolol HCl, and salicylamide, for which qualitative screening methods have not been published in the Minilab manual or FDA Compendium. These methods use relatively inexpensive and nontoxic “green solvents” for sample and standard solution and mobile phase preparation, Merck Premium Purity silica gel 60 F254 plates, automated standard and sample solution...
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Development of Quantitative HPTLC–Densitometry Methods for the Analysis of Amiodarone HCl, Carvedilol, Doxylamine Succinate, Magnesium Salicylate, Metoprolol Succinate, Nebivolol HCl, and Salicylamide Using a Model Process Developed Earlier for the T
Acta Chromatographica, 2018Co-Authors: K Nguyen, Joseph ShermaAbstract:A model process, previously developed in a series of studies, allows for the transfer of thin-layer chromatography (TLC) methods for qualitative screening of counterfeit drug products published in the Global Pharma Health Fund (GPHF) Minilab manual and US Food and Drug Administration (FDA) Compendium of Unofficial Methods for Screening of Pharmaceuticals by TLC to quantitative high-performance TLC (HPTLC)–densitometry methods. This article describes HPTLC–densitometry methods developed and validated according to this model process for pharmaceutical products of amiodarone HCl, carvedilol, doxylamine succinate, Magnesium Salicylate, metoprolol succinate, nebivolol HCl, and salicylamide, for which qualitative screening methods have not been published in the Minilab manual or FDA Compendium. These methods use relatively inexpensive and nontoxic “green solvents” for sample and standard solution and mobile phase preparation, Merck Premium Purity silica gel 60 F254 plates, automated standard and sample solution...
Constantin Turta - One of the best experts on this subject based on the ideXlab platform.
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Homo- and heteronuclear iron complexes {Fe2MO} with salicylic acid: Synthesis, structures, and physicochemical properties
Russian Journal of Coordination Chemistry, 2009Co-Authors: V. V. Gorinchoy, V. E. Zubareva, Sergiu Shova, V. N. Szafranski, Janusz Lipkowski, Nicolae Stanica, Yu. A. Simonov, Constantin TurtaAbstract:A reaction of iron nitrate with Magnesium Salicylate and reactions of iron and cobalt chlorides with ammonium Salicylate in the presence of water, methanol, DMAA, and DMF gave the trinuclear heterometallic complexes: [hexa-μ-salicylato-μ3-oxo-0.4-dimethylacetamide-2.6-aquadiiron(III)Magnesium(II)] tetra(dimethylacetamide), [Fe2MgO(SalH)6(DMAA)0.4(H2O)2.6]·4DMAA (I); [hexa-μ]-salicylato-μ3-oxo(dimethanol)aquadiiron(III)cobalt(II)] dimethylformamide · 2.5-hydrate, [Fe2CoO(SalH)6(CH3OH)2(H2O)] · DMF · 2.5H2O (II); and [hexa-μ-salicylato-μ3-oxotriaquatriiron(III)] chloride dimethylacetamide monohydrate, [Fe3O(SalH)6(H2O)3]Cl · DMAA · H2O (III). The X-ray study revealed that the molecular structures of complexes I and II are [Fe2 IIIMII(μ3-O)(RCOO)6L3] · nSolv. The IR and Mossbauer spectra of complexes I–III were examined; their magnetochemical and thermal properties were studied. The parameters of the Mossbauer spectra (δNa + = 0.69 ± 0.03 mm/s, ΔE Q = 0.76–1.08 mm/s, 300 K) suggest the high-spin state of the Fe3+ ions in complexes I–III (S = 5/2). The paramagnetic Fe3+ ions are involved in antiferromagnetic exchange interactions with the parameter J = −44 cm−1, g = 2.05 (for I). Complexes I–III are thermally unstable.
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Homo- and heteronuclear iron complexes {Fe_2MO} with salicylic acid: Synthesis, structures, and physicochemical properties
Russian Journal of Coordination Chemistry, 2009Co-Authors: V. V. Gorinchoy, V. E. Zubareva, Sergiu Shova, V. N. Szafranski, Janusz Lipkowski, Nicolae Stanica, Yu. A. Simonov, Constantin TurtaAbstract:A reaction of iron nitrate with Magnesium Salicylate and reactions of iron and cobalt chlorides with ammonium Salicylate in the presence of water, methanol, DMAA, and DMF gave the trinuclear heterometallic complexes: [hexa-μ-salicylato-μ_3-oxo-0.4-dimethylacetamide-2.6-aquadiiron(III)Magnesium(II)] tetra(dimethylacetamide), [Fe_2MgO(SalH)_6(DMAA)_0.4(H_2O)_2.6]·4DMAA ( I ); [hexa-μ]-salicylato-μ_3-oxo(dimethanol)aquadiiron(III)cobalt(II)] dimethylformamide · 2.5-hydrate, [Fe_2CoO(SalH)_6(CH_3OH)_2(H_2O)] · DMF · 2.5H_2O ( II ); and [hexa-μ-salicylato-μ_3-oxotriaquatriiron(III)] chloride dimethylacetamide monohydrate, [Fe_3O(SalH)_6(H_2O)_3]Cl · DMAA · H_2O ( III ). The X-ray study revealed that the molecular structures of complexes I and II are [Fe_2 ^IIIM^II(μ_3-O)(RCOO)_6L_3] · n Solv. The IR and Mössbauer spectra of complexes I–III were examined; their magnetochemical and thermal properties were studied. The parameters of the Mössbauer spectra (δ_Na ^+ = 0.69 ± 0.03 mm/s, ΔE_ Q = 0.76–1.08 mm/s, 300 K) suggest the high-spin state of the Fe^3+ ions in complexes I–III ( S = 5/2). The paramagnetic Fe^3+ ions are involved in antiferromagnetic exchange interactions with the parameter J = −44 cm^−1, g = 2.05 (for I ). Complexes I–III are thermally unstable.
Keli Zhang - One of the best experts on this subject based on the ideXlab platform.
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Kinetics of the Thermal Decomposition of Magnesium Salicylate Powder in Air
Chemical Research in Chinese Universities, 2006Co-Authors: Kahirou Diakite, Jianhe Hong, Dan Zhan, Keli ZhangAbstract:Simultaneous thermogravimetry-differential thermal analysis (TG-DTA) was used to study the kinetics and the degradation of Magnesium Salicylate(C 14 H 10 MgO 6 ) in air. The results show that the decomposition proceeds through two steps. The kinetics of the first decomposition step was studied. The activation energies were calculated by using the Friedman and Flynn Wall Ozawa(FWO) methods, and the most probable kinetic model function was estimated using the multiple linear regression method. The values of the correlated kinetic parameters for the first decomposition step are E = 152.97 kJ/mol, lg( A /S −1 ) = 10.78, f (α) = (1−α) n (1 + K cat α), n = 0.691, and K cat = 1. 3048.
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Kinetics of the Thermal Decomposition of Magnesium Salicylate Powder in Air
Chemical Research in Chinese Universities, 2006Co-Authors: Kahirou Diakite, Jianhe Hong, Dan Zhan, Keli ZhangAbstract:Simultaneous thermogravimetry-differential thermal analysis (TG-DTA) was used to study the kinetics and the degradation of Magnesium Salicylate(C 14 H 10 MgO 6 ) in air. The results show that the decomposition proceeds through two steps. The kinetics of the first decomposition step was studied. The activation energies were calculated by using the Friedman and Flynn Wall Ozawa(FWO) methods, and the most probable kinetic model function was estimated using the multiple linear regression method. The values of the correlated kinetic parameters for the first decomposition step are E = 152.97 kJ/mol, lg( A /S −1 ) = 10.78, f (α) = (1−α) n (1 + K cat α), n = 0.691, and K cat = 1. 3048.
V. V. Gorinchoy - One of the best experts on this subject based on the ideXlab platform.
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Homo- and heteronuclear iron complexes {Fe2MO} with salicylic acid: Synthesis, structures, and physicochemical properties
Russian Journal of Coordination Chemistry, 2009Co-Authors: V. V. Gorinchoy, V. E. Zubareva, Sergiu Shova, V. N. Szafranski, Janusz Lipkowski, Nicolae Stanica, Yu. A. Simonov, Constantin TurtaAbstract:A reaction of iron nitrate with Magnesium Salicylate and reactions of iron and cobalt chlorides with ammonium Salicylate in the presence of water, methanol, DMAA, and DMF gave the trinuclear heterometallic complexes: [hexa-μ-salicylato-μ3-oxo-0.4-dimethylacetamide-2.6-aquadiiron(III)Magnesium(II)] tetra(dimethylacetamide), [Fe2MgO(SalH)6(DMAA)0.4(H2O)2.6]·4DMAA (I); [hexa-μ]-salicylato-μ3-oxo(dimethanol)aquadiiron(III)cobalt(II)] dimethylformamide · 2.5-hydrate, [Fe2CoO(SalH)6(CH3OH)2(H2O)] · DMF · 2.5H2O (II); and [hexa-μ-salicylato-μ3-oxotriaquatriiron(III)] chloride dimethylacetamide monohydrate, [Fe3O(SalH)6(H2O)3]Cl · DMAA · H2O (III). The X-ray study revealed that the molecular structures of complexes I and II are [Fe2 IIIMII(μ3-O)(RCOO)6L3] · nSolv. The IR and Mossbauer spectra of complexes I–III were examined; their magnetochemical and thermal properties were studied. The parameters of the Mossbauer spectra (δNa + = 0.69 ± 0.03 mm/s, ΔE Q = 0.76–1.08 mm/s, 300 K) suggest the high-spin state of the Fe3+ ions in complexes I–III (S = 5/2). The paramagnetic Fe3+ ions are involved in antiferromagnetic exchange interactions with the parameter J = −44 cm−1, g = 2.05 (for I). Complexes I–III are thermally unstable.
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Homo- and heteronuclear iron complexes {Fe_2MO} with salicylic acid: Synthesis, structures, and physicochemical properties
Russian Journal of Coordination Chemistry, 2009Co-Authors: V. V. Gorinchoy, V. E. Zubareva, Sergiu Shova, V. N. Szafranski, Janusz Lipkowski, Nicolae Stanica, Yu. A. Simonov, Constantin TurtaAbstract:A reaction of iron nitrate with Magnesium Salicylate and reactions of iron and cobalt chlorides with ammonium Salicylate in the presence of water, methanol, DMAA, and DMF gave the trinuclear heterometallic complexes: [hexa-μ-salicylato-μ_3-oxo-0.4-dimethylacetamide-2.6-aquadiiron(III)Magnesium(II)] tetra(dimethylacetamide), [Fe_2MgO(SalH)_6(DMAA)_0.4(H_2O)_2.6]·4DMAA ( I ); [hexa-μ]-salicylato-μ_3-oxo(dimethanol)aquadiiron(III)cobalt(II)] dimethylformamide · 2.5-hydrate, [Fe_2CoO(SalH)_6(CH_3OH)_2(H_2O)] · DMF · 2.5H_2O ( II ); and [hexa-μ-salicylato-μ_3-oxotriaquatriiron(III)] chloride dimethylacetamide monohydrate, [Fe_3O(SalH)_6(H_2O)_3]Cl · DMAA · H_2O ( III ). The X-ray study revealed that the molecular structures of complexes I and II are [Fe_2 ^IIIM^II(μ_3-O)(RCOO)_6L_3] · n Solv. The IR and Mössbauer spectra of complexes I–III were examined; their magnetochemical and thermal properties were studied. The parameters of the Mössbauer spectra (δ_Na ^+ = 0.69 ± 0.03 mm/s, ΔE_ Q = 0.76–1.08 mm/s, 300 K) suggest the high-spin state of the Fe^3+ ions in complexes I–III ( S = 5/2). The paramagnetic Fe^3+ ions are involved in antiferromagnetic exchange interactions with the parameter J = −44 cm^−1, g = 2.05 (for I ). Complexes I–III are thermally unstable.
