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B.d. Flockhart - One of the best experts on this subject based on the ideXlab platform.

Jan Meijer - One of the best experts on this subject based on the ideXlab platform.

Xi Kong - One of the best experts on this subject based on the ideXlab platform.

Perminder Sachdev - One of the best experts on this subject based on the ideXlab platform.

  • Magnetic Resonance Spectroscopy and its Applications in Psychiatry
    Australian and New Zealand Journal of Psychiatry, 2020
    Co-Authors: Gin S. Malhi, Michael Valenzuela, Perminder Sachdev
    Abstract:

    Objective: This paper briefly describes neuroimaging using Magnetic Resonance Spectroscopy (MRS) and provides a systematic review of its application to psychiatric disorders.Method: A literature review (Index Medicus/Medline) was carried out, as well as a review of other relevant papers and data known to the authors.Results: Magnetic Resonance Spectroscopy is a complex and sophisticated neuroimaging technique that allows reliable and reproducible quantification of brain neurochemistry provided its limitations are respected. In some branches of medicine it is already used clinically, for instance, to diagnose tumours and in psychiatry its applications are gradually extending beyond research. Neurochemical changes have been found in a variety of brain regions in dementia, schizophrenia and affective disorders and promising discoveries have also been made in anxiety disorders.Conclusions: Magnetic Resonance Spectroscopy is a non-invasive investigative technique that has provided useful insights into the bioc...

  • Magnetic Resonance Spectroscopy and its applications in psychiatry
    Australian and New Zealand Journal of Psychiatry, 2002
    Co-Authors: Gin S. Malhi, Michael Valenzuela, Wei Wen, Perminder Sachdev
    Abstract:

    OBJECTIVE: This paper briefly describes neuroimaging using Magnetic Resonance Spectroscopy (MRS) and provides a systematic review of its application to psychiatric disorders. METHOD: A literature review (Index Medicus/Medline) was carried out, as well as a review of other relevant papers and data known to the authors. RESULTS: Magnetic Resonance Spectroscopy is a complex and sophisticated neuroimaging technique that allows reliable and reproducible quantification of brain neurochemistry provided its limitations are respected. In some branches of medicine it is already used clinically, for instance, to diagnose tumours and in psychiatry its applications are gradually extending beyond research. Neurochemical changes have been found in a variety of brain regions in dementia, schizophrenia and affective disorders and promising discoveries have also been made in anxiety disorders. CONCLUSION: Magnetic Resonance Spectroscopy is a non-invasive investigative technique that has provided useful insights into the biochemical basis of many neuropsychiatric disorders. It allows direct measurement, in vivo, of medication levels within the brain and has made it possible to track the neurochemical changes that occur as a consequence of disease and ageing or in response to treatment. It is an extremely useful advance in neuroimaging technology and one that will undoubtedly have many clinical uses in the near future.

Jeffrey A Burgess - One of the best experts on this subject based on the ideXlab platform.

  • torque mixing Magnetic Resonance Spectroscopy
    Science, 2015
    Co-Authors: M. Belov, Jeffrey A Burgess, D. T. Grandmont, Z. Diao, Joseph E. Losby, Fatemeh Fani Sani
    Abstract:

    A universal, torque-mixing method for Magnetic Resonance Spectroscopy is presented. In analogy to Resonance detection by Magnetic induction, the transverse component of a precessing dipole moment can be measured in sensitive broadband Spectroscopy, here using a resonant mechanical torque sensor. Unlike induction, the torque amplitude allows equilibrium Magnetic properties to be monitored simultaneously with the spin dynamics. Comprehensive electron spin Resonance spectra of a single-crystal, mesoscopic yttrium iron garnet disk at room temperature reveal assisted switching between magnetization states and mode-dependent spin Resonance interactions with nanoscale surface imperfections. The rich detail allows analysis of even complex three-dimensional spin textures. The flexibility of microelectromechanical and optomechanical devices combined with broad generality and capabilities of torque-mixing Magnetic Resonance Spectroscopy offers great opportunities for development of integrated devices.

  • Torque-mixing Magnetic Resonance Spectroscopy
    Science, 2015
    Co-Authors: Joseph E. Losby, M. Belov, Jeffrey A Burgess, F. Fani Sani, D. T. Grandmont, Z. Diao, S. R. Compton, D. Vick, W. K. Hiebert, K Mohammad
    Abstract:

    Mechanically detected spin Resonances\nThe interaction of spins in a sample with a Magnetic field can generate forces that can be sensed with cantilever probes. Losby et al. measured the Resonance signals at room temperature with a micromechanical torque magnetometer. The difference between two applied radio-frequency signals corresponded to the mechanical frequency of the resonator. This approach revealed the vortex core dynamics of the ferri-toferro–Magnetic transition in a micrometer-sized yttrium-iron-garnet single-crystal disk.\nScience, this issue p. 798\nA universal, torque-mixing method for Magnetic Resonance Spectroscopy is presented. In analogy to Resonance detection by Magnetic induction, the transverse component of a precessing dipole moment can be measured in sensitive broadband Spectroscopy, here using a resonant mechanical torque sensor. Unlike induction, the torque amplitude allows equilibrium Magnetic properties to be monitored simultaneously with the spin dynamics. Comprehensive electron spin Resonance spectra of a single-crystal, mesoscopic yttrium iron garnet disk at room temperature reveal assisted switching between magnetization states and mode-dependent spin Resonance interactions with nanoscale surface imperfections. The rich detail allows analysis of even complex three-dimensional spin textures. The flexibility of microelectromechanical and optomechanical devices combined with broad generality and capabilities of torque-mixing Magnetic Resonance Spectroscopy offers great opportunities for development of integrated devices.\nElectronic spin Resonances of a Magnetic single crystal are measured with a mechanical torque sensor.\nElectronic spin Resonances of a Magnetic single crystal are measured with a mechanical torque sensor.