The Experts below are selected from a list of 250614 Experts worldwide ranked by ideXlab platform
Edward J Wilkinson - One of the best experts on this subject based on the ideXlab platform.
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vulvar lymphangioma circumscriptum a report of 3 cases 2 associated with vulvar carcinoma and 1 with hidradenitis suppurativa
Journal of Lower Genital Tract Disease, 2010Co-Authors: Shireen Madani Sims, Frederick W Mclean, John D Davis, Linda S Morgan, Edward J WilkinsonAbstract:: Vulvar lymphangioma circumscriptum is a rare, benign proliferation of the lymphatic system that presents a diagnostic and Management Challenge. It may be confused with condyloma acuminata, molluscum contagiosum, or other vulvar disorders. Treatment options include observation, surgical excision, laser ablation, or sclerosing therapy. We report 3 cases, 2 associated with vulvar squamous cell carcinoma and 1 with hidradenitis suppurativa.
Federico P Girardi - One of the best experts on this subject based on the ideXlab platform.
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spinal lumbar synovial cysts diagnosis and Management Challenge
European Spine Journal, 2006Co-Authors: Amir M Khan, Federico P GirardiAbstract:Sophisticated and newer imaging capabilities have resulted in increased reporting and treatment options of spinal lumbar synovial cysts (LSS). Most of the patients with lumbar cysts tend to be in their sixth decade of life with a slight female predominance. The incidence of LSS is thought to be less than 0.5% of the general symptomatic population. They may be asymptomatic and found incidentally or the epidural growth of cysts into the spinal canal can cause compression of neural structures and hence associated clinical symptoms. Most of the symptomatic LSS patients present with radicular pain and neurological deficits. Spinal synovial cysts are commonly found at L4-5 level, the site of maximum mobility. They may be unilateral or bilateral and at one or multilevel. MRI is considered the tool of choice for its diagnosis. The etiology of LSS is still unclear, but underlying spinal instability, facet joint arthropathy and degenerative spondylolisthesis has a strong association for worsening symptoms and formation of spinal cysts. Synovial cysts resistant to conservative therapy should be treated surgically. Resection and decompression with or without fusion and instrumentation remains an appropriate option. Synovial cysts may recur following surgery. The optimal approach for patients with juxtafacet LSS remains unclear. The best surgical treatment option for each particular individual should be tailored depending upon the symptoms, radiological findings and other co morbidities.
Deepa Anand - One of the best experts on this subject based on the ideXlab platform.
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stump un stumped anti tumor response to anaplastic lymphoma kinase alk inhibitor based targeted therapy in uterine inflammatory myofibroblastic tumor with myxoid features harboring dctn1 alk fusion
Journal of Hematology & Oncology, 2015Co-Authors: Vivek Subbiah, Caitlin Mcmahon, Shreyaskumar Patel, Ishwaria Mohan Subbiah, Chimela Ohaji, Dhakshina Moorthy Ganeshan, Elvio G Silva, Julia A Elvin, Ralph Zinner, Deepa AnandAbstract:Background Recurrent, metastatic mesenchymal myxoid tumors of the gynecologic tract present a Management Challenge as there is minimal evidence to guide systemic therapy. Such tumors also present a diagnostic dilemma, as myxoid features are observed in leiomyosarcomas, inflammatory myofibroblastic tumors (IMT), and mesenchymal myxoid tumors. Comprehensive genomic profiling was performed in the course of clinical care on a case of a recurrent, metastatic myxoid uterine malignancy (initially diagnosed as smooth muscle tumor of uncertain malignant potential (STUMP)), to guide identify targeted therapeutic options. To our knowledge, this case represents the first report of clinical response to targeted therapy in a tumor harboring a DCTN1-ALK fusion protein.
Shireen Madani Sims - One of the best experts on this subject based on the ideXlab platform.
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vulvar lymphangioma circumscriptum a report of 3 cases 2 associated with vulvar carcinoma and 1 with hidradenitis suppurativa
Journal of Lower Genital Tract Disease, 2010Co-Authors: Shireen Madani Sims, Frederick W Mclean, John D Davis, Linda S Morgan, Edward J WilkinsonAbstract:: Vulvar lymphangioma circumscriptum is a rare, benign proliferation of the lymphatic system that presents a diagnostic and Management Challenge. It may be confused with condyloma acuminata, molluscum contagiosum, or other vulvar disorders. Treatment options include observation, surgical excision, laser ablation, or sclerosing therapy. We report 3 cases, 2 associated with vulvar squamous cell carcinoma and 1 with hidradenitis suppurativa.
Benoit H Mulsant - One of the best experts on this subject based on the ideXlab platform.
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fluoxetine induced syndrome of inappropriate antidiuretic hormone secretion a geriatric case report and a review of the literature
Journal of Geriatric Psychiatry and Neurology, 1994Co-Authors: Richard W Druckenbrod, Benoit H MulsantAbstract:In a frail, elderly, depressed patient, hyponatremia can present a difficult diagnostic and Management Challenge. We report the case of a severely depressed 83-year-old woman presenting with severe hyponatremia, eventually attributed to a syndrome of inappropriate, antidiuretic hormone (SIADH) secretion induced by fluoxetine. This case is discussed in the context of the multiple potential causes of hyponatremia in an elderly depressed patient, with a focus on fluoxetine-induced SIADH, as reported in 9 other published cases.
