The Experts below are selected from a list of 23091 Experts worldwide ranked by ideXlab platform

Gianpaolo Papaccio - One of the best experts on this subject based on the ideXlab platform.

  • human Mandible Bone defect repair by the grafting of dental pulp stem progenitor cells and collagen sponge biocomplexes
    European Cells & Materials, 2009
    Co-Authors: Riccardo Daquino, Alfredo De Rosa, Vladimiro Lanza, Virginia Tirino, Luigi Laino, Antonio Graziano, Vincenzo Desiderio, Gregorio Laino, Gianpaolo Papaccio
    Abstract:

    In this study we used a biocomplex constructed from dental pulp stem/progenitor cells (DPCs) and a collagen sponge scaffold for oro-maxillo-facial (OMF) Bone tissue repair in patients requiring extraction of their third molars. The experiments were carried out according to our Internal Ethical Committee Guidelines and written informed consent was obtained from the patients. The patients presented with bilateral Bone reabsorption of the alveolar ridge distal to the second molar secondary to impaction of the third molar on the cortical alveolar lamina, producing a defect without walls, of at least 1.5 cm in height. This clinical condition does not permit spontaneous Bone repair after extraction of the third molar, and eventually leads to loss also of the adjacent second molar. Maxillary third molars were extracted first for DPC isolation and expansion. The cells were then seeded onto a collagen sponge scaffold and the obtained biocomplex was used to fill in the injury site left by extraction of the mandibular third molars. Three months after autologous DPC grafting, alveolar Bone of patients had optimal vertical repair and complete restoration of periodontal tissue back to the second molars, as assessed by clinical probing and X-rays. Histological observations clearly demonstrated the complete regeneration of Bone at the injury site. Optimal Bone regeneration was evident one year after grafting. This clinical study demonstrates that a DPC/collagen sponge biocomplex can completely restore human Mandible Bone defects and indicates that this cell population could be used for the repair and/or regeneration of tissues and organs.

  • Human Mandible Bone defect repair by the grafting of dental pulp stem/progenitor cells and collagen sponge biocomplexes.
    European cells & materials, 2009
    Co-Authors: Riccardo D'aquino, Alfredo De Rosa, Vladimiro Lanza, Virginia Tirino, Luigi Laino, Antonio Graziano, Vincenzo Desiderio, Gregorio Laino, Gianpaolo Papaccio
    Abstract:

    In this study we used a biocomplex constructed from dental pulp stem/progenitor cells (DPCs) and a collagen sponge scaffold for oro-maxillo-facial (OMF) Bone tissue repair in patients requiring extraction of their third molars. The experiments were carried out according to our Internal Ethical Committee Guidelines and written informed consent was obtained from the patients. The patients presented with bilateral Bone reabsorption of the alveolar ridge distal to the second molar secondary to impaction of the third molar on the cortical alveolar lamina, producing a defect without walls, of at least 1.5 cm in height. This clinical condition does not permit spontaneous Bone repair after extraction of the third molar, and eventually leads to loss also of the adjacent second molar. Maxillary third molars were extracted first for DPC isolation and expansion. The cells were then seeded onto a collagen sponge scaffold and the obtained biocomplex was used to fill in the injury site left by extraction of the mandibular third molars. Three months after autologous DPC grafting, alveolar Bone of patients had optimal vertical repair and complete restoration of periodontal tissue back to the second molars, as assessed by clinical probing and X-rays. Histological observations clearly demonstrated the complete regeneration of Bone at the injury site. Optimal Bone regeneration was evident one year after grafting. This clinical study demonstrates that a DPC/collagen sponge biocomplex can completely restore human Mandible Bone defects and indicates that this cell population could be used for the repair and/or regeneration of tissues and organs.

Alfredo De Rosa - One of the best experts on this subject based on the ideXlab platform.

  • human Mandible Bone defect repair by the grafting of dental pulp stem progenitor cells and collagen sponge biocomplexes
    European Cells & Materials, 2009
    Co-Authors: Riccardo Daquino, Alfredo De Rosa, Vladimiro Lanza, Virginia Tirino, Luigi Laino, Antonio Graziano, Vincenzo Desiderio, Gregorio Laino, Gianpaolo Papaccio
    Abstract:

    In this study we used a biocomplex constructed from dental pulp stem/progenitor cells (DPCs) and a collagen sponge scaffold for oro-maxillo-facial (OMF) Bone tissue repair in patients requiring extraction of their third molars. The experiments were carried out according to our Internal Ethical Committee Guidelines and written informed consent was obtained from the patients. The patients presented with bilateral Bone reabsorption of the alveolar ridge distal to the second molar secondary to impaction of the third molar on the cortical alveolar lamina, producing a defect without walls, of at least 1.5 cm in height. This clinical condition does not permit spontaneous Bone repair after extraction of the third molar, and eventually leads to loss also of the adjacent second molar. Maxillary third molars were extracted first for DPC isolation and expansion. The cells were then seeded onto a collagen sponge scaffold and the obtained biocomplex was used to fill in the injury site left by extraction of the mandibular third molars. Three months after autologous DPC grafting, alveolar Bone of patients had optimal vertical repair and complete restoration of periodontal tissue back to the second molars, as assessed by clinical probing and X-rays. Histological observations clearly demonstrated the complete regeneration of Bone at the injury site. Optimal Bone regeneration was evident one year after grafting. This clinical study demonstrates that a DPC/collagen sponge biocomplex can completely restore human Mandible Bone defects and indicates that this cell population could be used for the repair and/or regeneration of tissues and organs.

  • Human Mandible Bone defect repair by the grafting of dental pulp stem/progenitor cells and collagen sponge biocomplexes.
    European cells & materials, 2009
    Co-Authors: Riccardo D'aquino, Alfredo De Rosa, Vladimiro Lanza, Virginia Tirino, Luigi Laino, Antonio Graziano, Vincenzo Desiderio, Gregorio Laino, Gianpaolo Papaccio
    Abstract:

    In this study we used a biocomplex constructed from dental pulp stem/progenitor cells (DPCs) and a collagen sponge scaffold for oro-maxillo-facial (OMF) Bone tissue repair in patients requiring extraction of their third molars. The experiments were carried out according to our Internal Ethical Committee Guidelines and written informed consent was obtained from the patients. The patients presented with bilateral Bone reabsorption of the alveolar ridge distal to the second molar secondary to impaction of the third molar on the cortical alveolar lamina, producing a defect without walls, of at least 1.5 cm in height. This clinical condition does not permit spontaneous Bone repair after extraction of the third molar, and eventually leads to loss also of the adjacent second molar. Maxillary third molars were extracted first for DPC isolation and expansion. The cells were then seeded onto a collagen sponge scaffold and the obtained biocomplex was used to fill in the injury site left by extraction of the mandibular third molars. Three months after autologous DPC grafting, alveolar Bone of patients had optimal vertical repair and complete restoration of periodontal tissue back to the second molars, as assessed by clinical probing and X-rays. Histological observations clearly demonstrated the complete regeneration of Bone at the injury site. Optimal Bone regeneration was evident one year after grafting. This clinical study demonstrates that a DPC/collagen sponge biocomplex can completely restore human Mandible Bone defects and indicates that this cell population could be used for the repair and/or regeneration of tissues and organs.

Vladimiro Lanza - One of the best experts on this subject based on the ideXlab platform.

  • human Mandible Bone defect repair by the grafting of dental pulp stem progenitor cells and collagen sponge biocomplexes
    European Cells & Materials, 2009
    Co-Authors: Riccardo Daquino, Alfredo De Rosa, Vladimiro Lanza, Virginia Tirino, Luigi Laino, Antonio Graziano, Vincenzo Desiderio, Gregorio Laino, Gianpaolo Papaccio
    Abstract:

    In this study we used a biocomplex constructed from dental pulp stem/progenitor cells (DPCs) and a collagen sponge scaffold for oro-maxillo-facial (OMF) Bone tissue repair in patients requiring extraction of their third molars. The experiments were carried out according to our Internal Ethical Committee Guidelines and written informed consent was obtained from the patients. The patients presented with bilateral Bone reabsorption of the alveolar ridge distal to the second molar secondary to impaction of the third molar on the cortical alveolar lamina, producing a defect without walls, of at least 1.5 cm in height. This clinical condition does not permit spontaneous Bone repair after extraction of the third molar, and eventually leads to loss also of the adjacent second molar. Maxillary third molars were extracted first for DPC isolation and expansion. The cells were then seeded onto a collagen sponge scaffold and the obtained biocomplex was used to fill in the injury site left by extraction of the mandibular third molars. Three months after autologous DPC grafting, alveolar Bone of patients had optimal vertical repair and complete restoration of periodontal tissue back to the second molars, as assessed by clinical probing and X-rays. Histological observations clearly demonstrated the complete regeneration of Bone at the injury site. Optimal Bone regeneration was evident one year after grafting. This clinical study demonstrates that a DPC/collagen sponge biocomplex can completely restore human Mandible Bone defects and indicates that this cell population could be used for the repair and/or regeneration of tissues and organs.

  • Human Mandible Bone defect repair by the grafting of dental pulp stem/progenitor cells and collagen sponge biocomplexes.
    European cells & materials, 2009
    Co-Authors: Riccardo D'aquino, Alfredo De Rosa, Vladimiro Lanza, Virginia Tirino, Luigi Laino, Antonio Graziano, Vincenzo Desiderio, Gregorio Laino, Gianpaolo Papaccio
    Abstract:

    In this study we used a biocomplex constructed from dental pulp stem/progenitor cells (DPCs) and a collagen sponge scaffold for oro-maxillo-facial (OMF) Bone tissue repair in patients requiring extraction of their third molars. The experiments were carried out according to our Internal Ethical Committee Guidelines and written informed consent was obtained from the patients. The patients presented with bilateral Bone reabsorption of the alveolar ridge distal to the second molar secondary to impaction of the third molar on the cortical alveolar lamina, producing a defect without walls, of at least 1.5 cm in height. This clinical condition does not permit spontaneous Bone repair after extraction of the third molar, and eventually leads to loss also of the adjacent second molar. Maxillary third molars were extracted first for DPC isolation and expansion. The cells were then seeded onto a collagen sponge scaffold and the obtained biocomplex was used to fill in the injury site left by extraction of the mandibular third molars. Three months after autologous DPC grafting, alveolar Bone of patients had optimal vertical repair and complete restoration of periodontal tissue back to the second molars, as assessed by clinical probing and X-rays. Histological observations clearly demonstrated the complete regeneration of Bone at the injury site. Optimal Bone regeneration was evident one year after grafting. This clinical study demonstrates that a DPC/collagen sponge biocomplex can completely restore human Mandible Bone defects and indicates that this cell population could be used for the repair and/or regeneration of tissues and organs.

Virginia Tirino - One of the best experts on this subject based on the ideXlab platform.

  • human Mandible Bone defect repair by the grafting of dental pulp stem progenitor cells and collagen sponge biocomplexes
    European Cells & Materials, 2009
    Co-Authors: Riccardo Daquino, Alfredo De Rosa, Vladimiro Lanza, Virginia Tirino, Luigi Laino, Antonio Graziano, Vincenzo Desiderio, Gregorio Laino, Gianpaolo Papaccio
    Abstract:

    In this study we used a biocomplex constructed from dental pulp stem/progenitor cells (DPCs) and a collagen sponge scaffold for oro-maxillo-facial (OMF) Bone tissue repair in patients requiring extraction of their third molars. The experiments were carried out according to our Internal Ethical Committee Guidelines and written informed consent was obtained from the patients. The patients presented with bilateral Bone reabsorption of the alveolar ridge distal to the second molar secondary to impaction of the third molar on the cortical alveolar lamina, producing a defect without walls, of at least 1.5 cm in height. This clinical condition does not permit spontaneous Bone repair after extraction of the third molar, and eventually leads to loss also of the adjacent second molar. Maxillary third molars were extracted first for DPC isolation and expansion. The cells were then seeded onto a collagen sponge scaffold and the obtained biocomplex was used to fill in the injury site left by extraction of the mandibular third molars. Three months after autologous DPC grafting, alveolar Bone of patients had optimal vertical repair and complete restoration of periodontal tissue back to the second molars, as assessed by clinical probing and X-rays. Histological observations clearly demonstrated the complete regeneration of Bone at the injury site. Optimal Bone regeneration was evident one year after grafting. This clinical study demonstrates that a DPC/collagen sponge biocomplex can completely restore human Mandible Bone defects and indicates that this cell population could be used for the repair and/or regeneration of tissues and organs.

  • Human Mandible Bone defect repair by the grafting of dental pulp stem/progenitor cells and collagen sponge biocomplexes.
    European cells & materials, 2009
    Co-Authors: Riccardo D'aquino, Alfredo De Rosa, Vladimiro Lanza, Virginia Tirino, Luigi Laino, Antonio Graziano, Vincenzo Desiderio, Gregorio Laino, Gianpaolo Papaccio
    Abstract:

    In this study we used a biocomplex constructed from dental pulp stem/progenitor cells (DPCs) and a collagen sponge scaffold for oro-maxillo-facial (OMF) Bone tissue repair in patients requiring extraction of their third molars. The experiments were carried out according to our Internal Ethical Committee Guidelines and written informed consent was obtained from the patients. The patients presented with bilateral Bone reabsorption of the alveolar ridge distal to the second molar secondary to impaction of the third molar on the cortical alveolar lamina, producing a defect without walls, of at least 1.5 cm in height. This clinical condition does not permit spontaneous Bone repair after extraction of the third molar, and eventually leads to loss also of the adjacent second molar. Maxillary third molars were extracted first for DPC isolation and expansion. The cells were then seeded onto a collagen sponge scaffold and the obtained biocomplex was used to fill in the injury site left by extraction of the mandibular third molars. Three months after autologous DPC grafting, alveolar Bone of patients had optimal vertical repair and complete restoration of periodontal tissue back to the second molars, as assessed by clinical probing and X-rays. Histological observations clearly demonstrated the complete regeneration of Bone at the injury site. Optimal Bone regeneration was evident one year after grafting. This clinical study demonstrates that a DPC/collagen sponge biocomplex can completely restore human Mandible Bone defects and indicates that this cell population could be used for the repair and/or regeneration of tissues and organs.

Luigi Laino - One of the best experts on this subject based on the ideXlab platform.

  • human Mandible Bone defect repair by the grafting of dental pulp stem progenitor cells and collagen sponge biocomplexes
    European Cells & Materials, 2009
    Co-Authors: Riccardo Daquino, Alfredo De Rosa, Vladimiro Lanza, Virginia Tirino, Luigi Laino, Antonio Graziano, Vincenzo Desiderio, Gregorio Laino, Gianpaolo Papaccio
    Abstract:

    In this study we used a biocomplex constructed from dental pulp stem/progenitor cells (DPCs) and a collagen sponge scaffold for oro-maxillo-facial (OMF) Bone tissue repair in patients requiring extraction of their third molars. The experiments were carried out according to our Internal Ethical Committee Guidelines and written informed consent was obtained from the patients. The patients presented with bilateral Bone reabsorption of the alveolar ridge distal to the second molar secondary to impaction of the third molar on the cortical alveolar lamina, producing a defect without walls, of at least 1.5 cm in height. This clinical condition does not permit spontaneous Bone repair after extraction of the third molar, and eventually leads to loss also of the adjacent second molar. Maxillary third molars were extracted first for DPC isolation and expansion. The cells were then seeded onto a collagen sponge scaffold and the obtained biocomplex was used to fill in the injury site left by extraction of the mandibular third molars. Three months after autologous DPC grafting, alveolar Bone of patients had optimal vertical repair and complete restoration of periodontal tissue back to the second molars, as assessed by clinical probing and X-rays. Histological observations clearly demonstrated the complete regeneration of Bone at the injury site. Optimal Bone regeneration was evident one year after grafting. This clinical study demonstrates that a DPC/collagen sponge biocomplex can completely restore human Mandible Bone defects and indicates that this cell population could be used for the repair and/or regeneration of tissues and organs.

  • Human Mandible Bone defect repair by the grafting of dental pulp stem/progenitor cells and collagen sponge biocomplexes.
    European cells & materials, 2009
    Co-Authors: Riccardo D'aquino, Alfredo De Rosa, Vladimiro Lanza, Virginia Tirino, Luigi Laino, Antonio Graziano, Vincenzo Desiderio, Gregorio Laino, Gianpaolo Papaccio
    Abstract:

    In this study we used a biocomplex constructed from dental pulp stem/progenitor cells (DPCs) and a collagen sponge scaffold for oro-maxillo-facial (OMF) Bone tissue repair in patients requiring extraction of their third molars. The experiments were carried out according to our Internal Ethical Committee Guidelines and written informed consent was obtained from the patients. The patients presented with bilateral Bone reabsorption of the alveolar ridge distal to the second molar secondary to impaction of the third molar on the cortical alveolar lamina, producing a defect without walls, of at least 1.5 cm in height. This clinical condition does not permit spontaneous Bone repair after extraction of the third molar, and eventually leads to loss also of the adjacent second molar. Maxillary third molars were extracted first for DPC isolation and expansion. The cells were then seeded onto a collagen sponge scaffold and the obtained biocomplex was used to fill in the injury site left by extraction of the mandibular third molars. Three months after autologous DPC grafting, alveolar Bone of patients had optimal vertical repair and complete restoration of periodontal tissue back to the second molars, as assessed by clinical probing and X-rays. Histological observations clearly demonstrated the complete regeneration of Bone at the injury site. Optimal Bone regeneration was evident one year after grafting. This clinical study demonstrates that a DPC/collagen sponge biocomplex can completely restore human Mandible Bone defects and indicates that this cell population could be used for the repair and/or regeneration of tissues and organs.