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Richard B Francoeur - One of the best experts on this subject based on the ideXlab platform.

  • symptom profiles of subsyndromal Depression in disease clusters of diabetes excess weight and progressive cerebrovascular conditions a promising new type of finding from a reliable innovation to estimate exhaustively specified multiple indicators mul
    Diabetes Metabolic Syndrome and Obesity: Targets and Therapy, 2016
    Co-Authors: Richard B Francoeur
    Abstract:

    Addressing subsyndromal Depression in cerebrovascular conditions, diabetes, and obesity reduces morbidity and risk of major Depression. However, Depression may be Masked because self-reported symptoms may not reveal dysphoric (sad) mood. In this study, the first wave (2,812 elders) from the New Haven Epidemiological Study of the Elderly (EPESE) was used. These population-weighted data combined a stratified, systematic, clustered random sample from independent residences and a census of senior housing. Physical conditions included progressive cerebrovascular disease (CVD; hypertension, silent CVD, stroke, and vascular cognitive impairment [VCI]) and co-occurring excess weight and/or diabetes. These conditions and interactions (clusters) simultaneously predicted 20 Depression items and a latent trait of Depression in participants with subsyndromal (including subthreshold) Depression (11≤ Center for Epidemiologic Studies Depression Scale [CES-D] score ≤27). The option for maximum likelihood estimation with standard errors that are robust to non-normality and non-independence in complex random samples (MLR) in Mplus and an innovation created by the author were used for estimating unbiased effects from latent trait models with exhaustive specification. Symptom profiles reveal Masked Depression in 1) older males, related to the metabolic syndrome (hypertension-overweight-diabetes; silent CVD-overweight; and silent CVD-diabetes) and 2) older females or the full sample, related to several diabetes and/or overweight clusters that involve stroke or VCI. Several other disease clusters are equivocal regarding Masked Depression; a couple do emphasize dysphoric mood. Replicating findings could identify subgroups for cost-effective screening of subsyndromal Depression.

Khrustaleva L. O. - One of the best experts on this subject based on the ideXlab platform.

  • Assessment of the dynamics of depressive disorders in patients with coronary heart disease depending on the method of restoration of blood supply to the heart.
    Dnipro State Medical University, 2018
    Co-Authors: Pertseva N. O., Khrustaleva L. O.
    Abstract:

    The aim of the study was to assess the symptoms of Depression during a 1-years observation in patients with coronary heart disease, depending on the method of restoration of blood supply to the heart. The study included 215 patients with ischemic heart disease who during 2010-2016 received treatment in the departments of cardiology, interventional cardiology and cardiac surgery of KU «Dnepropetrovsk Regional Clinical Center of Cardiology and Cardiosurgery DOR». All patients underwent invasive coronary angiography and were administered conservative or surgical treatment - aortocoronary bypass grafting or stenting of the coronary arteries. The level of Depression was determined by Zung’s Self-Rating Depression Scale – SDS three times: at the initial stage of treatment, after three months and 1 year after treatment. It was determined that in patients with IHD, the frequency of depressive states and conditions close to them varies from 81.97% (95% CI 70.53 to 89.62) in patients who are prescribed bypass and to 98.55% (95% CI 92.24 - 99.74) in patients with conservative treatment. The vast majority of patients in all groups are represented by patients with mild or Masked Depression. 4.71% of cases of true Depression in the coronary artery stenting group and 5.8% – in the conservative treatment group were revealed. According to the correlation analysis, the dependence of the average Depression level on the chosen treatment method was found (ρ=0.19; р=0.027). The choice of a surgical or conser­vative method of treatment can affect general level of mood and indirectly – quality of life in the long-term period

Rollin M Gallagher - One of the best experts on this subject based on the ideXlab platform.

  • why is Depression comorbid with chronic myofascial face pain a family study test of alternative hypotheses
    Pain, 1999
    Co-Authors: Bruce P Dohrenwend, Karen G Raphael, Joseph J Marbach, Rollin M Gallagher
    Abstract:

    A number of explanations have been proposed to account for findings that rates of Depression are elevated in persons with chronic, non-malignant pain disorders (CNPDs); for example, that CNPDs are variants of Depression (e.g. 'Masked Depression'), that the stress of living with CNPDs contribute to the onset of Depression ('diathesis-stress'), or that the correlation of CNPDs and Depression is a methodological artifact of studying treatment-seeking samples. These alternative hypotheses are tested for one specific CNPD, chronic myofascial face pain, using a family study methodology. The procedure was to conduct direct psychiatric interviews with 106 patients with a history of carefully diagnosed myofascial face pain, 118 acquaintance controls without personal histories of myofascial face pain, and a random sample of adult first degree relatives of these case and control probands. The probands were further subdivided into four roughly equal samples consisting of cases with and without personal histories of major depressive disorder (MDD), and controls with and without personal histories of MDD. Dates of initial onsets of myofascial face pain and MDD in patient probands were obtained from interviews and records. The main results were that, compared to control probands without personal histories of MDD, MDD and depressive spectrum disorders (DSD) were elevated in the first degree relatives of control probands with personal histories of early onset MDD, but not in the first degree relatives of myofascial face pain probands with or without personal histories of early or late onset MDD. This outcome is consistent with the hypothesis that living with chronic myofascial face pain contributes to elevated rates of Depression. It is inconsistent with the alternative hypotheses that this CNPD is a variant of Depression or that the elevated MDD rates are simply an artifact of selection into treatment. The implications of these results and additional results consistent with them are discussed.

Masaru Hosoda - One of the best experts on this subject based on the ideXlab platform.

Jasna Mathew - One of the best experts on this subject based on the ideXlab platform.

  • Treatment of Cases with Features of Depression using Kent’s Rubrics
    2019
    Co-Authors: Jasna Mathew
    Abstract:

    BACKGROUND: Depression is a common mental disorder that presents with a low or depressed mood, loss of interest or pleasure, decreased energy, feelings of guilt or low selfworth, disturbed sleep or appetite, and poor concentration. Majority of patients with Depression present to physicians with complaints of medically unexplained somatic symptoms or Masked Depression. Further, the rates of depressive disorders are higher among the chronic medically ill persons and in primary care patients. According to the latest estimates from WHO, more than 300 million people are now living with Depression. In October 2016, National Institute of Mental Health and Neurosciences (NIMHANS) in Bengaluru released a mental health survey, said that the incidence of Depression is roughly one in every 20 Indian or 7.5% of the population. The World Health Organization estimates that nearly 170,000 people are living with Depression in India. As part of quality of life, optimizing mental health is of prior value. The systematic and holistic homoeopathic interventions are of higher value which can build the comfort zone in the patients with Depression. OBJECTIVES: 1. To find out effectiveness of Kent repertory in indicating simillimum for Depression. 2. To prepare a data of frequently used rubrics for Depression from Kent repertory. MATERIALS AND METHODS: 30 cases with features of Depression were included for the study. Cases were recorded in the pre structured SKHMC case format. Intensity of Depression was measured using HAM-D scale. Repertorial totality was erected according to Kent’s repertory. Prescription was done with reference to standard text books of Materia Medica. Dose, frequency and repetition was based on subjects susceptibility. Assessment and evaluation was done after 4 months with HAM-D scale. Observations were noted in tables and charts. Statistical analysis has been done and results were presented. RESULT: Based on the study, most frequent rubrics observed were Mind - Weeping. Tearful mood, etc, Mind - Sensitive, Generalities - Weakness and Mind – Irritability. Nux Vomica and Sepia were being the best remedy for Depression. A statistically significant difference in the mean scores of HAM-D scale, using the paired t‑test, was observed. CONCLUSION: A course of Homoeopathic treatment is associated with significant benefits in patients with features of Depression, as measured by HAM-D scale. Kent’s rubrics are effective in suggesting a simillimum for treatment of cases with features of Depression