The Experts below are selected from a list of 222 Experts worldwide ranked by ideXlab platform

Geoffrey A T Targett - One of the best experts on this subject based on the ideXlab platform.

  • the epidemiology of plasmodium falciparum gametocytes weapons of Mass Dispersion
    Trends in Parasitology, 2006
    Co-Authors: Chris Drakeley, Robert W Sauerwein, Colin J Sutherland, Teun J Bousema, Geoffrey A T Targett
    Abstract:

    Much of the epidemiology of Plasmodium falciparum in Sub-Saharan Africa focuses on the prevalence patterns of asexual parasites in people of different ages, whereas the gametocytes that propagate the disease are often neglected. One expected benefit of the widespread introduction of artemisinin-based combination therapy for malaria is a reduction in gametocyte carriage. However, the factors that affect the transmission of parasites from humans to mosquitoes show complex dynamics in relation to the intensity and seasonality of malaria transmission, and thus such benefits might not be automatic. Here, we review data on gametocyte carriage in the context of the development of naturally acquired immunity and population infectivity.

  • The epidemiology of Plasmodium falciparum gametocytes: weapons of Mass Dispersion
    Trends in Parasitology, 2006
    Co-Authors: Chris Drakeley, J. Teun Bousema, Colin Sutherland, Robert W Sauerwein, Geoffrey A T Targett
    Abstract:

    Much of the epidemiology of Plasmodium falciparum in Sub-Saharan Africa focuses on the prevalence patterns of asexual parasites in people of different ages, whereas the gametocytes that propagate the disease are often neglected. One expected benefit of the widespread introduction of artemisinin-based combination therapy for malaria is a reduction in gametocyte carriage. However, the factors that affect the transmission of parasites from humans to mosquitoes show complex dynamics in relation to the intensity and seasonality of malaria transmission, and thus such benefits might not be automatic. Here, we review data on gametocyte carriage in the context of the development of naturally acquired immunity and population infectivity. © 2006 Elsevier Ltd. All rights reserved.

Chris Drakeley - One of the best experts on this subject based on the ideXlab platform.

  • the epidemiology of plasmodium falciparum gametocytes weapons of Mass Dispersion
    Trends in Parasitology, 2006
    Co-Authors: Chris Drakeley, Robert W Sauerwein, Colin J Sutherland, Teun J Bousema, Geoffrey A T Targett
    Abstract:

    Much of the epidemiology of Plasmodium falciparum in Sub-Saharan Africa focuses on the prevalence patterns of asexual parasites in people of different ages, whereas the gametocytes that propagate the disease are often neglected. One expected benefit of the widespread introduction of artemisinin-based combination therapy for malaria is a reduction in gametocyte carriage. However, the factors that affect the transmission of parasites from humans to mosquitoes show complex dynamics in relation to the intensity and seasonality of malaria transmission, and thus such benefits might not be automatic. Here, we review data on gametocyte carriage in the context of the development of naturally acquired immunity and population infectivity.

  • The epidemiology of Plasmodium falciparum gametocytes: weapons of Mass Dispersion
    Trends in Parasitology, 2006
    Co-Authors: Chris Drakeley, J. Teun Bousema, Colin Sutherland, Robert W Sauerwein, Geoffrey A T Targett
    Abstract:

    Much of the epidemiology of Plasmodium falciparum in Sub-Saharan Africa focuses on the prevalence patterns of asexual parasites in people of different ages, whereas the gametocytes that propagate the disease are often neglected. One expected benefit of the widespread introduction of artemisinin-based combination therapy for malaria is a reduction in gametocyte carriage. However, the factors that affect the transmission of parasites from humans to mosquitoes show complex dynamics in relation to the intensity and seasonality of malaria transmission, and thus such benefits might not be automatic. Here, we review data on gametocyte carriage in the context of the development of naturally acquired immunity and population infectivity. © 2006 Elsevier Ltd. All rights reserved.

C. K. G. Piyadasa - One of the best experts on this subject based on the ideXlab platform.

  • A constant-momentum/energy-selector time-of-flight Mass spectrometer
    Journal of the American Society for Mass Spectrometry, 2007
    Co-Authors: C. P. Santacruz, P. Håkansson, D. F. Barofsky, C. K. G. Piyadasa
    Abstract:

    A matrix assisted laser desorption/ionization time-of-flight Mass spectrometer has been built with an ion source that can be operated in either constant-energy or constant-momentum acceleration modes. A decreasing electric field distribution in the ion-accelerating region makes it possible to direct ions onto a space-focal plane in either modes of operation. Ions produced in the constant-momentum mode have velocities and, thus, flight times that are linearly dependent on Mass and kinetic energies that are inversely dependent on Mass. The linear Mass Dispersion doubles Mass resolving power of ions accelerated with space-focusing conditions in constant-momentum mode. The Mass-dependent kinetic energy is exploited to disperse ions according to Mass in a simple kinetic energy filter constructed from two closely spaced, oblique ion reflectors. Focusing velocity of ions of the same Mass can substantially improve ion selection for subsequent post source decay or tandem time-of-flight analyses.

Robert W Sauerwein - One of the best experts on this subject based on the ideXlab platform.

  • the epidemiology of plasmodium falciparum gametocytes weapons of Mass Dispersion
    Trends in Parasitology, 2006
    Co-Authors: Chris Drakeley, Robert W Sauerwein, Colin J Sutherland, Teun J Bousema, Geoffrey A T Targett
    Abstract:

    Much of the epidemiology of Plasmodium falciparum in Sub-Saharan Africa focuses on the prevalence patterns of asexual parasites in people of different ages, whereas the gametocytes that propagate the disease are often neglected. One expected benefit of the widespread introduction of artemisinin-based combination therapy for malaria is a reduction in gametocyte carriage. However, the factors that affect the transmission of parasites from humans to mosquitoes show complex dynamics in relation to the intensity and seasonality of malaria transmission, and thus such benefits might not be automatic. Here, we review data on gametocyte carriage in the context of the development of naturally acquired immunity and population infectivity.

  • The epidemiology of Plasmodium falciparum gametocytes: weapons of Mass Dispersion
    Trends in Parasitology, 2006
    Co-Authors: Chris Drakeley, J. Teun Bousema, Colin Sutherland, Robert W Sauerwein, Geoffrey A T Targett
    Abstract:

    Much of the epidemiology of Plasmodium falciparum in Sub-Saharan Africa focuses on the prevalence patterns of asexual parasites in people of different ages, whereas the gametocytes that propagate the disease are often neglected. One expected benefit of the widespread introduction of artemisinin-based combination therapy for malaria is a reduction in gametocyte carriage. However, the factors that affect the transmission of parasites from humans to mosquitoes show complex dynamics in relation to the intensity and seasonality of malaria transmission, and thus such benefits might not be automatic. Here, we review data on gametocyte carriage in the context of the development of naturally acquired immunity and population infectivity. © 2006 Elsevier Ltd. All rights reserved.

C. P. Santacruz - One of the best experts on this subject based on the ideXlab platform.

  • A constant-momentum/energy-selector time-of-flight Mass spectrometer
    Journal of the American Society for Mass Spectrometry, 2007
    Co-Authors: C. P. Santacruz, P. Håkansson, D. F. Barofsky, C. K. G. Piyadasa
    Abstract:

    A matrix assisted laser desorption/ionization time-of-flight Mass spectrometer has been built with an ion source that can be operated in either constant-energy or constant-momentum acceleration modes. A decreasing electric field distribution in the ion-accelerating region makes it possible to direct ions onto a space-focal plane in either modes of operation. Ions produced in the constant-momentum mode have velocities and, thus, flight times that are linearly dependent on Mass and kinetic energies that are inversely dependent on Mass. The linear Mass Dispersion doubles Mass resolving power of ions accelerated with space-focusing conditions in constant-momentum mode. The Mass-dependent kinetic energy is exploited to disperse ions according to Mass in a simple kinetic energy filter constructed from two closely spaced, oblique ion reflectors. Focusing velocity of ions of the same Mass can substantially improve ion selection for subsequent post source decay or tandem time-of-flight analyses.