The Experts below are selected from a list of 21939 Experts worldwide ranked by ideXlab platform
Antonio Mutti - One of the best experts on this subject based on the ideXlab platform.
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polybrominated diphenyl ether pbde flame retardants environmental contamination human body burden and potential adverse health effects
Acta bio-medica : Atenei Parmensis, 2008Co-Authors: Gennaro Giordano, Sara Tagliaferri, Andrea Caglieri, Antonio MuttiAbstract:Polybrominated diphenyl ethers (PBDEs) are an important class of flame retardants, widely used in a variety of consumer products. In the past several years, PBDEs have become widespread environmental pollutants, and have been detected in water, soil, air, animals and human tissues. Exposure occurs in particular through the diet and the indoor environment. Infants and toddlers have the highest body burden, due to exposure via Maternal Milk and through house dust. Tetra-, penta- and hexa-BDEs are the congeners most commonly found in humans. Recent concerns on possible adverse health effects of PBDEs are focusing on their potential endocrine disrupting effects and on developmental neurotoxicity.
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polybrominated diphenyl ether pbde flame retardants environmental contamination human body burden and potential adverse health effects
Acta bio-medica : Atenei Parmensis, 2008Co-Authors: Lucio G Costa, Gennaro Giordano, Sara Tagliaferri, Andrea Caglieri, Antonio MuttiAbstract:Polybrominated diphenyl ethers (PBDEs) are an important class of flame retardants, widely used in a variety of consumer products. In the past several years, PBDEs have become widespread environmental pollutants, and have been detected in water, soil, air, animals and human tissues. Exposure occurs in particular through the diet and the indoor environment. Infants and toddlers have the highest body burden, due to exposure via Maternal Milk and through house dust. Tetra-, penta- and hexa-BDEs are the congeners most commonly found in humans. Recent concerns on possible adverse health effects of PBDEs are focusing on their potential endocrine disrupting effects and on developmental neurotoxicity.
Maureen Hack - One of the best experts on this subject based on the ideXlab platform.
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the effect of neonatal Maternal Milk feeding on the neurodevelopmental outcome of very low birth weight infants
Journal of Developmental and Behavioral Pediatrics, 2004Co-Authors: Lydia Furman, Gerry H Taylor, Nori Minich, Deanne Wilsoncostello, Harriet Friedman, Maureen HackAbstract:The effect of Maternal Milk feeding during the first 4 weeks of life on neurodevelopmental outcomes at 20 months corrected age (CA) of singleton very low birth weight (VLBW) (< 1.5 kg) infants was examined. Ninety-eight VLBW infants born from January 1997 to February 1999 were followed to 20 months CA (mean birth weight, 1012 g; gestational age, 27 weeks). Maternal Milk intake was calculated as both mean milliliters per kilogram per day and graded doses. Outcomes included the Bayley Mental Development Index (MDI) and Psychomotor Development Index (PDI), and rates of cerebral palsy (CP) and of overall neurodevelopmental impairment. After adjusting for neonatal and social risk, results revealed no effect of Maternal Milk on outcomes. MDI was predicted by both social and neonatal risk, and PDI, CP, and neurodevelopmental impairment were predicted by neonatal risk. In this small, high-risk group of VLBW infants, the effects of social and neonatal risk appear to outweigh any possible benefits of Maternal Milk on neurodevelopmental outcome.
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the effect of Maternal Milk on neonatal morbidity of very low birth weight infants
JAMA Pediatrics, 2003Co-Authors: Lydia Furman, Gerry H Taylor, Nori Minich, Maureen HackAbstract:Objective To examine the dose effect of Maternal Milk on neonatal morbidity of very low-birth-weight ( Design Prospective observational study. Setting An urban tertiary care neonatal intensive care unit and follow-up clinic. Population One hundred nineteen singleton very low-birth-weight infants admitted from January 1, 1997, to February 14, 1999 (mean birth weight, 1056 g; mean gestational age, 28 weeks; 57% male; and 43% white). Methods A comparison of the effect on neonatal outcomes of daily graded doses (1-24, 25-49, and ≥50 mL/kg of body weight) of Maternal Milk through week 4 of life vs a reference group receiving no Maternal Milk. Main Outcome Measures Neonatal outcomes examined included rates of sepsis after age 5 days, retinopathy of prematurity, chronic lung disease, necrotizing enterocolitis, jaundice, duration of ventilator dependence, and length of hospital stay. Results Seventy-nine infants (66%) received Maternal Milk, of whom 32 received at least 50 mL/kg per day through week 4 of life. Poisson regression analysis adjusting for birth weight, sex, and ethnicity revealed that the mean number of episodes of sepsis for infants receiving at least 50 mL/kg per day was lower by a factor of 0.27 (95% confidence interval, 0.08-0.95) compared with infants receiving no Maternal Milk. There was no effect of Maternal Milk on other neonatal outcomes. Conclusions A daily threshold amount of at least 50 mL/kg of Maternal Milk through week 4 of life is needed to decrease the rate of sepsis in very low-birth-weight infants, but Maternal Milk does not affect other neonatal morbidities.
Chisato Mori - One of the best experts on this subject based on the ideXlab platform.
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Perinatal Exposure to Brominated Flame Retardants and Polychlorinated Biphenyls in Japan
Endocrine journal, 2008Co-Authors: Yukiko Kawashiro, Hideki Fukata, Mariko Omori-inoue, Kiyoshi Kubonoya, Tomomi Jotaki, Hidetaka Takigam, Shin-ichi Sakai, Chisato MoriAbstract:Brominated flame retardants (BFRs) are used to prevent combustion in consumer products. Examples of BFRs are polybrominated diphenyl ethers (PBDEs), tetrabromobisphenol A (TBBPA), and tribromophenol (TBP). These compounds are reported to have adverse effects on human health and endocrine disrupting effects. The purpose of this study was to identify the Japanese perinatal exposure to PBDEs, hydroxylated PBDE metabolites (OH-PBDEs), TBBPA, and TBP compared with polychlorinated biphenyls (PCBs) and hydroxylated PCB metabolites (OH-PCBs). We investigated the concentrations of these compounds in Maternal blood, Maternal Milk, cord blood, and umbilical cords from 16 Japanese mother-infant pairs by HRGC/HRMS. PBDEs were detected in all samples of Maternal blood (mean+/-SD; median=25+/-23 pg/g; 18 pg/g wet weight), Maternal Milk (140+/-220 pg/g; 59 pg/g wet weight), cord blood (4.8+/-6.5 pg/g; 1.6 pg/g wet weight), and umbilical cords (3.1+/-3.1 pg/g; 2.1 pg/g wet weight). The mothers were divided into two groups, a high-concentration group and a low-concentration group. The percentage of BDE-47 showed the greatest difference between the two groups. 6-OH-BDE-47, TBBPA, and TBP were detected in all umbilical cord samples (mean+/-SD; median=8.4+/-8.1 pg/g; 8.0 pg/g, 16+/-5.5 pg/g; 15 pg/g, and 33+/-8.2 pg/g; 32 pg/g wet weight respectively), but not in all Maternal blood or cord blood samples. These results indicate that OH-PBDEs, TBBPA, and TBP, in addition to PBDEs, PCBs, and OH-PCBs, pass through the blood-placenta barrier and are retained in the umbilical cord.
Section On Breastfeeding - One of the best experts on this subject based on the ideXlab platform.
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donor human Milk for the high risk infant preparation safety and usage options in the united states
Pediatrics, 2017Co-Authors: Section On BreastfeedingAbstract:The use of donor human Milk is increasing for high-risk infants, primarily for infants born weighing <1500 g or those who have severe intestinal disorders. Pasteurized donor Milk may be considered in situations in which the supply of Maternal Milk is insufficient. The use of pasteurized donor Milk is safe when appropriate measures are used to screen donors and collect, store, and pasteurize the Milk and then distribute it through established human Milk banks. The use of nonpasteurized donor Milk and other forms of direct, Internet-based, or informal human Milk sharing does not involve this level of safety and is not recommended. It is important that health care providers counsel families considering Milk sharing about the risks of bacterial or viral contamination of nonpasteurized human Milk and about the possibilities of exposure to medications, drugs, or herbs in human Milk. Currently, the use of pasteurized donor Milk is limited by its availability and affordability. The development of public policy to improve and expand access to pasteurized donor Milk, including policies that support improved governmental and private financial support for donor Milk banks and the use of donor Milk, is important.
Vincent W V Jaddoe - One of the best experts on this subject based on the ideXlab platform.
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Maternal First-Trimester Cow-Milk Intake Is Positively Associated with Childhood General and Abdominal Visceral Fat Mass and Lean Mass but Not with Other Cardiometabolic Risk Factors at the Age of 10 Years
'Oxford University Press (OUP)', 2021Co-Authors: E. Voerman, R. Gaillard, M.l. Geurtsen, Vincent W V JaddoeAbstract:Background: Higher Maternal cow-Milk intake during pregnancy is associated with higher fetal growth measures and higher birth weight. Objective: The aim of this study was to assess the associations of Maternal Milk intake during pregnancy with body fat measures and cardiometabolic risk factors at the age of 10 y. Methods: In a population-based cohort of Dutch mothers and their children (n = 2466) followed from early pregnancy onwards, we assessed Maternal first-trimester Milk intake (Milk and Milk drinks) by food-frequency questionnaire. Maternal Milk intake was categorized into 0-0.9, 1-1.9, 2-2.9, 3-3.9, 4-4.9, and ≥5 g
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Maternal Milk consumption fetal growth and the risks of neonatal complications the generation r study
The American Journal of Clinical Nutrition, 2011Co-Authors: Denise H M Heppe, Hanneke Den Breeijen, Hein Raat, Eric A P Steegers, Sten P Willemsen, Albert Hofman, Vincent W V JaddoeAbstract:BACKGROUND: Maternal cow-Milk consumption may increase birth weight. Previous studies did not assess the association of Maternal Milk consumption with trimester-specific fetal growth. OBJECTIVE: The objective was to assess associations of first-trimester Maternal Milk consumption with fetal growth characteristics in different trimesters and the risk of neonatal complications. DESIGN: In total, 3405 mothers participating in a prospective cohort study completed a 293-item semiquantitative food-frequency questionnaire to obtain information about dairy consumption during the first trimester of pregnancy. Fetal head circumference, femur length, and weight were estimated in the second and third trimesters by ultrasonography. RESULTS: Maternal Milk consumption of >3 glasses/d was associated with greater fetal weight gain in the third trimester of pregnancy, which led to an 88-g (95% CI: 39, 135 g) higher birth weight than that with Milk consumption of 0 to 1 glass/d. In addition, head circumference tended to be 2.3 cm (95% CI: -0.0, 4.6 cm) larger when mothers consumed >3 glasses/d. Maternal Milk consumption was not associated with length growth. Maternal protein intake (P for trend = 0.01), but not fat or carbohydrate intake, from dairy products was associated with higher birth weight. This association appeared to be limited to Milk (P for trend < 0.01), whereas protein intake from nondairy food or cheese was not associated with birth weight. CONCLUSIONS: Maternal Milk consumption is associated with greater fetal weight gain. The association seems to be due to Milk protein, or Milk components closely associated with protein, rather than to the fat or carbohydrate fraction of Milk.
