Maximum Likelihood Estimates

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Xiaojun Zhu - One of the best experts on this subject based on the ideXlab platform.

Xiaohua Zhou - One of the best experts on this subject based on the ideXlab platform.

Frantisek Matus - One of the best experts on this subject based on the ideXlab platform.

  • generalized Maximum Likelihood Estimates for exponential families
    Probability Theory and Related Fields, 2008
    Co-Authors: Ivan Csiszar, Frantisek Matus
    Abstract:

    For a standard full exponential family on $$\mathbb R^d$$ , or its canonically convex subfamily, the generalized Maximum Likelihood estimator is an extension of the mapping that assigns to the mean $$a\in\mathbb R^d$$ of a sample for which a maximizer $$\vartheta^*$$ of a corresponding Likelihood function exists, the member of the family parameterized by $$\vartheta^*$$ . This extension assigns to each $$a\in\mathbb R^d$$ with the Likelihood function bounded above, a member of the closure of the family in variation distance. Its detailed description, complete characterization of domain and range, and additional results are presented, not imposing any regularity assumptions. In addition to basic convex analysis tools, the authors’ prior results on convex cores of measures and closures of exponential families are used.

  • generalized Maximum Likelihood Estimates for exponential families
    International Symposium on Information Theory, 2006
    Co-Authors: Ivan Csiszar, Frantisek Matus
    Abstract:

    For a standard full exponential family on Ropfd, or its canonically convex subfamily, the generalized Maximum Likelihood estimator is an extension of the mapping that assigns to the mean alpha isin Ropfd of a sample for which a maximizer v* of the corresponding Likelihood function exists, the member of the family parameterized by v*. This extension assigns to each alpha; isin Ropfd with the Likelihood function bounded above, a member of the closure of the family in variation distance. Its detailed description, complete characterization of domain and range, and additional results are presented, in a general setting. In addition to basic convex analysis tools, the authors' prior results on convex cores of measures and closures of exponential families are used

D. Kececioglu - One of the best experts on this subject based on the ideXlab platform.

  • Maximum Likelihood Estimates, from censored data, for mixed-Weibull distributions
    IEEE Transactions on Reliability, 1992
    Co-Authors: S. Jiang, D. Kececioglu
    Abstract:

    An algorithm for estimating the parameters of mixed-Weibull distributions from censored data is presented. The algorithm follows the principle of the MLE (Maximum Likelihood estimate) through the EM (expectation and maximization) algorithm, and it is derived for both postmortem and non-postmortem time-to-failure data. The MLEs of the nonpostmortem data are obtained for mixed-Weibull distributions with up to 14 parameters in a five-subpopulation mixed-Weibull distribution. Numerical examples indicate that some of the log-Likelihood functions of the mixed-Weibull distributions have multiple local maxima; therefore the algorithm should start at several initial guesses of the parameters set. It is shown that the EM algorithm is very efficient. On the average for two-Weibull mixtures with a sample size of 200, the CPU time (on a VAX 8650) is 0.13 s/iteration. The number of iterations depends on the characteristics of the mixture. The number of iterations is small if the subpopulations in the mixture are well separated. Generally, the algorithm is not sensitive to the initial guesses of the parameters.

Andrew R Francis - One of the best experts on this subject based on the ideXlab platform.

  • Maximum Likelihood Estimates of pairwise rearrangement distances
    Journal of Theoretical Biology, 2017
    Co-Authors: Stuart Serdoz, Attila Egrinagy, Jeremy G Sumner, Barbara R Holland, P D Jarvis, Mark M Tanaka, Andrew R Francis
    Abstract:

    Accurate estimation of evolutionary distances between taxa is important for many phylogenetic reconstruction methods. Distances can be estimated using a range of different evolutionary models, from single nucleotide polymorphisms to large-scale genome rearrangements. Corresponding corrections for genome rearrangement distances fall into 3 categories: Empirical computational studies, Bayesian/MCMC approaches, and combinatorial approaches. Here, we introduce a Maximum Likelihood estimator for the inversion distance between a pair of genomes, using a group-theoretic approach to modelling inversions introduced recently. This MLE functions as a corrected distance: in particular, we show that because of the way sequences of inversions interact with each other, it is quite possible for minimal distance and MLE distance to differently order the distances of two genomes from a third. The second aspect tackles the problem of accounting for the symmetries of circular arrangements. While, generally, a frame of reference is locked, and all computation made accordingly, this work incorporates the action of the dihedral group so that distance Estimates are free from any a priori frame of reference. The philosophy of accounting for symmetries can be applied to any existing correction method, for which examples are offered.

  • Maximum Likelihood Estimates of pairwise rearrangement distances
    arXiv: Populations and Evolution, 2016
    Co-Authors: Stuart Serdoz, Attila Egrinagy, Jeremy G Sumner, Barbara R Holland, P D Jarvis, Mark M Tanaka, Andrew R Francis
    Abstract:

    Accurate estimation of evolutionary distances between taxa is important for many phylogenetic reconstruction methods. In the case of bacteria, distances can be estimated using a range of different evolutionary models, from single nucleotide polymorphisms to large-scale genome rearrangements. In the case of sequence evolution models (such as the Jukes-Cantor model and associated metric) have been used to correct pairwise distances. Similar correction methods for genome rearrangement processes are required to improve inference. Current attempts at correction fall into 3 categories: Empirical computational studies, Bayesian/MCMC approaches, and combinatorial approaches. Here we introduce a Maximum Likelihood estimator for the inversion distance between a pair of genomes, using the group-theoretic approach to modelling inversions introduced recently. This MLE functions as a corrected distance: in particular, we show that because of the way sequences of inversions interact with each other, it is quite possible for minimal distance and MLE distance to differently order the distances of two genomes from a third. This has obvious implications for the use of minimal distance in phylogeny reconstruction. The work also tackles the above problem allowing free rotation of the genome. Generally a frame of reference is locked, and all computation made accordingly. This work incorporates the action of the dihedral group so that distance Estimates are free from any a priori frame of reference.