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Mustafa Turan - One of the best experts on this subject based on the ideXlab platform.

  • The platelet count/Mean Corpuscular Hemoglobin ratio distinguishes combined iron and vitamin B12 deficiency from uncomplicated iron deficiency.
    International journal of hematology, 2005
    Co-Authors: Cengiz Beyan, Kürs¸at Kaptan, Esin Beyan, Mustafa Turan
    Abstract:

    Combined deficiencies of iron and cobalamin are common. The aims of this study were to investigate the significance of the parameters of the complete blood count (CBC) in differentiating microcytic anemia due to pure iron deficiency anemia (IDA) from anemia due to combined deficiencies of vitamin B12 and iron (IDA-B12). The study was carried out with 122 patients (100 female) who had microcytic red blood cell indices with IDA-B12 and 105 patients (95 female) with IDA. Group IDA-B12 patients had decreased Hemoglobin levels, Mean Corpuscular volumes, Mean Corpuscular Hemoglobin (MCH) levels, and MCH concentrations but had increased platelet counts (PLT). Using these parameters, we developed a PLT/MCH ratio parameter that has high values when IDA is accompanied by cobalamin deficiency. The cutoff value of >12.00, with a 74.6% sensitivity and a 41.9% specificity, appears to be the most convenient value for screening. We advise measuring the levels of cobalamin in patients with IDA associated with a high PLT/MCH ratio.

  • the platelet count Mean Corpuscular Hemoglobin ratio distinguishes combined iron and vitamin b12 deficiency from uncomplicated iron deficiency
    International Journal of Hematology, 2005
    Co-Authors: Cengiz Beyan, Kürs¸at Kaptan, Esin Beyan, Mustafa Turan
    Abstract:

    Combined deficiencies of iron and cobalamin are common. The aims of this study were to investigate the significance of the parameters of the complete blood count (CBC) in differentiating microcytic anemia due to pure iron deficiency anemia (IDA) from anemia due to combined deficiencies of vitamin B12 and iron (IDA-B12). The study was carried out with 122 patients (100 female) who had microcytic red blood cell indices with IDA-B12 and 105 patients (95 female) with IDA. Group IDA-B12 patients had decreased Hemoglobin levels, Mean Corpuscular volumes, Mean Corpuscular Hemoglobin (MCH) levels, and MCH concentrations but had increased platelet counts (PLT). Using these parameters, we developed a PLT/MCH ratio parameter that has high values when IDA is accompanied by cobalamin deficiency. The cutoff value of >12.00, with a 74.6% sensitivity and a 41.9% specificity, appears to be the most convenient value for screening. We advise measuring the levels of cobalamin in patients with IDA associated with a high PLT/MCH ratio.

Cengiz Beyan - One of the best experts on this subject based on the ideXlab platform.

  • The platelet count/Mean Corpuscular Hemoglobin ratio distinguishes combined iron and vitamin B12 deficiency from uncomplicated iron deficiency.
    International journal of hematology, 2005
    Co-Authors: Cengiz Beyan, Kürs¸at Kaptan, Esin Beyan, Mustafa Turan
    Abstract:

    Combined deficiencies of iron and cobalamin are common. The aims of this study were to investigate the significance of the parameters of the complete blood count (CBC) in differentiating microcytic anemia due to pure iron deficiency anemia (IDA) from anemia due to combined deficiencies of vitamin B12 and iron (IDA-B12). The study was carried out with 122 patients (100 female) who had microcytic red blood cell indices with IDA-B12 and 105 patients (95 female) with IDA. Group IDA-B12 patients had decreased Hemoglobin levels, Mean Corpuscular volumes, Mean Corpuscular Hemoglobin (MCH) levels, and MCH concentrations but had increased platelet counts (PLT). Using these parameters, we developed a PLT/MCH ratio parameter that has high values when IDA is accompanied by cobalamin deficiency. The cutoff value of >12.00, with a 74.6% sensitivity and a 41.9% specificity, appears to be the most convenient value for screening. We advise measuring the levels of cobalamin in patients with IDA associated with a high PLT/MCH ratio.

  • the platelet count Mean Corpuscular Hemoglobin ratio distinguishes combined iron and vitamin b12 deficiency from uncomplicated iron deficiency
    International Journal of Hematology, 2005
    Co-Authors: Cengiz Beyan, Kürs¸at Kaptan, Esin Beyan, Mustafa Turan
    Abstract:

    Combined deficiencies of iron and cobalamin are common. The aims of this study were to investigate the significance of the parameters of the complete blood count (CBC) in differentiating microcytic anemia due to pure iron deficiency anemia (IDA) from anemia due to combined deficiencies of vitamin B12 and iron (IDA-B12). The study was carried out with 122 patients (100 female) who had microcytic red blood cell indices with IDA-B12 and 105 patients (95 female) with IDA. Group IDA-B12 patients had decreased Hemoglobin levels, Mean Corpuscular volumes, Mean Corpuscular Hemoglobin (MCH) levels, and MCH concentrations but had increased platelet counts (PLT). Using these parameters, we developed a PLT/MCH ratio parameter that has high values when IDA is accompanied by cobalamin deficiency. The cutoff value of >12.00, with a 74.6% sensitivity and a 41.9% specificity, appears to be the most convenient value for screening. We advise measuring the levels of cobalamin in patients with IDA associated with a high PLT/MCH ratio.

Esin Beyan - One of the best experts on this subject based on the ideXlab platform.

  • The platelet count/Mean Corpuscular Hemoglobin ratio distinguishes combined iron and vitamin B12 deficiency from uncomplicated iron deficiency.
    International journal of hematology, 2005
    Co-Authors: Cengiz Beyan, Kürs¸at Kaptan, Esin Beyan, Mustafa Turan
    Abstract:

    Combined deficiencies of iron and cobalamin are common. The aims of this study were to investigate the significance of the parameters of the complete blood count (CBC) in differentiating microcytic anemia due to pure iron deficiency anemia (IDA) from anemia due to combined deficiencies of vitamin B12 and iron (IDA-B12). The study was carried out with 122 patients (100 female) who had microcytic red blood cell indices with IDA-B12 and 105 patients (95 female) with IDA. Group IDA-B12 patients had decreased Hemoglobin levels, Mean Corpuscular volumes, Mean Corpuscular Hemoglobin (MCH) levels, and MCH concentrations but had increased platelet counts (PLT). Using these parameters, we developed a PLT/MCH ratio parameter that has high values when IDA is accompanied by cobalamin deficiency. The cutoff value of >12.00, with a 74.6% sensitivity and a 41.9% specificity, appears to be the most convenient value for screening. We advise measuring the levels of cobalamin in patients with IDA associated with a high PLT/MCH ratio.

  • the platelet count Mean Corpuscular Hemoglobin ratio distinguishes combined iron and vitamin b12 deficiency from uncomplicated iron deficiency
    International Journal of Hematology, 2005
    Co-Authors: Cengiz Beyan, Kürs¸at Kaptan, Esin Beyan, Mustafa Turan
    Abstract:

    Combined deficiencies of iron and cobalamin are common. The aims of this study were to investigate the significance of the parameters of the complete blood count (CBC) in differentiating microcytic anemia due to pure iron deficiency anemia (IDA) from anemia due to combined deficiencies of vitamin B12 and iron (IDA-B12). The study was carried out with 122 patients (100 female) who had microcytic red blood cell indices with IDA-B12 and 105 patients (95 female) with IDA. Group IDA-B12 patients had decreased Hemoglobin levels, Mean Corpuscular volumes, Mean Corpuscular Hemoglobin (MCH) levels, and MCH concentrations but had increased platelet counts (PLT). Using these parameters, we developed a PLT/MCH ratio parameter that has high values when IDA is accompanied by cobalamin deficiency. The cutoff value of >12.00, with a 74.6% sensitivity and a 41.9% specificity, appears to be the most convenient value for screening. We advise measuring the levels of cobalamin in patients with IDA associated with a high PLT/MCH ratio.

Kürs¸at Kaptan - One of the best experts on this subject based on the ideXlab platform.

  • The platelet count/Mean Corpuscular Hemoglobin ratio distinguishes combined iron and vitamin B12 deficiency from uncomplicated iron deficiency.
    International journal of hematology, 2005
    Co-Authors: Cengiz Beyan, Kürs¸at Kaptan, Esin Beyan, Mustafa Turan
    Abstract:

    Combined deficiencies of iron and cobalamin are common. The aims of this study were to investigate the significance of the parameters of the complete blood count (CBC) in differentiating microcytic anemia due to pure iron deficiency anemia (IDA) from anemia due to combined deficiencies of vitamin B12 and iron (IDA-B12). The study was carried out with 122 patients (100 female) who had microcytic red blood cell indices with IDA-B12 and 105 patients (95 female) with IDA. Group IDA-B12 patients had decreased Hemoglobin levels, Mean Corpuscular volumes, Mean Corpuscular Hemoglobin (MCH) levels, and MCH concentrations but had increased platelet counts (PLT). Using these parameters, we developed a PLT/MCH ratio parameter that has high values when IDA is accompanied by cobalamin deficiency. The cutoff value of >12.00, with a 74.6% sensitivity and a 41.9% specificity, appears to be the most convenient value for screening. We advise measuring the levels of cobalamin in patients with IDA associated with a high PLT/MCH ratio.

  • the platelet count Mean Corpuscular Hemoglobin ratio distinguishes combined iron and vitamin b12 deficiency from uncomplicated iron deficiency
    International Journal of Hematology, 2005
    Co-Authors: Cengiz Beyan, Kürs¸at Kaptan, Esin Beyan, Mustafa Turan
    Abstract:

    Combined deficiencies of iron and cobalamin are common. The aims of this study were to investigate the significance of the parameters of the complete blood count (CBC) in differentiating microcytic anemia due to pure iron deficiency anemia (IDA) from anemia due to combined deficiencies of vitamin B12 and iron (IDA-B12). The study was carried out with 122 patients (100 female) who had microcytic red blood cell indices with IDA-B12 and 105 patients (95 female) with IDA. Group IDA-B12 patients had decreased Hemoglobin levels, Mean Corpuscular volumes, Mean Corpuscular Hemoglobin (MCH) levels, and MCH concentrations but had increased platelet counts (PLT). Using these parameters, we developed a PLT/MCH ratio parameter that has high values when IDA is accompanied by cobalamin deficiency. The cutoff value of >12.00, with a 74.6% sensitivity and a 41.9% specificity, appears to be the most convenient value for screening. We advise measuring the levels of cobalamin in patients with IDA associated with a high PLT/MCH ratio.

Weihao Kong - One of the best experts on this subject based on the ideXlab platform.

  • Mean Corpuscular Hemoglobin concentration correlates with prognosis of resected hepatocellular carcinoma.
    Biomarkers in medicine, 2020
    Co-Authors: Weihao Kong, Jun Zheng, Liang Chen, Xiaomin Zuo, Hengyi Wang, Xingyu Wang, Jia Yao, Wei Chen
    Abstract:

    Aim: To evaluate the prognostic role of Mean Corpuscular Hemoglobin concentration (MCHC) in hepatocellular carcinoma (HCC) after hepatectomy. Patients & methods: A total of 289 HCC patients were classified into two groups based on the cut-off value of MCHC. Significant prognostic factors were screened by univariate and multivariate analysis. Results: Low MCHC value was significantly associated with tumor diameter (p = 0.004) and vascular invasion (p = 0.038). Besides, Cox regression analysis showed that low MCHC was significantly associated with poor prognostic outcomes with HCC after hepatectomy (overall survival: hazard ratio: 0.372; 95% CI: 0.206-0.672; p = 0.001; recurrence-free survival: hazard ratio: 0.450; 95% confidence interval: 0.317-0.638; p 

  • Mean Corpuscular Hemoglobin concentration correlates with prognosis of resected hepatocellular carcinoma
    Biomarkers in Medicine, 2020
    Co-Authors: Weihao Kong, Jun Zheng, Liang Chen, Xiaomin Zuo, Hengyi Wang, Xingyu Wang, Jia Yao, Wei Chen
    Abstract:

    Aim: To evaluate the prognostic role of Mean Corpuscular Hemoglobin concentration (MCHC) in hepatocellular carcinoma (HCC) after hepatectomy. Patients & methods: A total of 289 HCC patients were classified into two groups based on the cut-off value of MCHC. Significant prognostic factors were screened by univariate and multivariate analysis. Results: Low MCHC value was significantly associated with tumor diameter (p = 0.004) and vascular invasion (p = 0.038). Besides, Cox regression analysis showed that low MCHC was significantly associated with poor prognostic outcomes with HCC after hepatectomy (overall survival: hazard ratio: 0.372; 95% CI: 0.206-0.672; p = 0.001; recurrence-free survival: hazard ratio: 0.450; 95% confidence interval: 0.317-0.638; p < 0.001). Conclusion: Preoperative MCHC can predict prognosis for patients with HCC, and the lower MCHC value was associated with poor prognosis after hepatectomy.