The Experts below are selected from a list of 315 Experts worldwide ranked by ideXlab platform

Mehdi Boukallel - One of the best experts on this subject based on the ideXlab platform.

  • Smart microrobots for Mechanical Cell characterization and Cell convoying.
    IEEE Transactions on Biomedical Engineering, 2007
    Co-Authors: Mehdi Boukallel, Monique Dauge, E. Piat, Michaël Gauthier, Joël Abadie
    Abstract:

    This paper deals with the effective of smart microrobots for both Mechanical Cell characterization and Cell convoying for in vitro fertilization. The first microrobotic device was developed to evaluate oocyte Mechanical behavior in order to sort oocytes. A multi-axial micro-force sensor based on a frictionless magnetic bearing was developed. The second microrobotic device presented is a Cell convoying device consisting of a wireless micropusher based on magnetic actuation. As wireless capabilities are supported by this microrobotic system, no power supply connections to the micropusher are needed. Preliminary experiments have been performed regarding both Cell transporting and bioMechanical characterization capabilities under in vitro conditions on human oocytes so as to demonstrate the viability and effectiveness of the proposed setups.

  • Smart microrobots for Mechanical Cell characterization and Cell convoying
    IEEE Transactions on Biomedical Engineering, 2007
    Co-Authors: Mehdi Boukallel, Michel Gauthier, Monique Dauge, E. Piat, Josiane Abadie
    Abstract:

    This paper deals with the effective design of smart microrobots for both Mechanical Cell characterization and Cell convoying for in vitro fertilization. The first microrobotic device was developed to evaluate oocyte Mechanical behavior in order to sort oocytes. A multi-axial micro-force sensor based on a frictionless magnetic bearing was developed. The second microrobotic device presented is a Cell convoying device consisting of a wireless micropusher based on magnetic actuation. As wireless capabilities are supported by this microrobotic system, no power supply connections to the micropusher are needed. Preliminary experiments have been performed regarding both Cell transporting and bioMechanical characterization capabilities under in vitro conditions on human oocytes so as to demonstrate the viability and effectiveness of the proposed setups.

Romain Levayer - One of the best experts on this subject based on the ideXlab platform.

  • Solid stress, competition for space and cancer: The opposing roles of Mechanical Cell competition in tumour initiation and growth
    Seminars in Cancer Biology, 2020
    Co-Authors: Romain Levayer
    Abstract:

    The regulation of Cell growth, Cell proliferation and Cell death is at the basis of the homeostasis of tissues. While they can be regulated by intrinsic and genetic factors, their response to external signals emanating from the local environment is also essential for tissue homeostasis. Tumour initiation and progression is based on the misregulation of growth, proliferation and death mostly through the accumulation of genetic mutations. Yet, there is an increasing body of evidences showing that tumour microenvironment also has a strong impact on cancer initiation and progression. This includes the Mechanical constrains and the compressive forces generated by the resistance of the surrounding tissue/matrix to tumour expansion. Recently, Mechanical stress has been proposed to promote competitive interactions between Cells through a process called Mechanical Cell competition. Cell population with a high proliferative rate can compact and eliminate the neighbouring Cells which are more sensitive to compaction. While this emerging concept has been recently validated in vivo, the relevance of this process during tumour progression has never been discussed extensively. In this review, I will first describe the phenomenology of Mechanical Cell competition focusing on the main parameters and the pathways regulating Cell elimination. I will then discuss the relevance of Mechanical Cell competition in tumour initiation and expansion while emphasizing its potential opposing contributions to tumourogenesis.

Joël Abadie - One of the best experts on this subject based on the ideXlab platform.

  • Smart microrobots for Mechanical Cell characterization and Cell convoying.
    IEEE Transactions on Biomedical Engineering, 2007
    Co-Authors: Mehdi Boukallel, Monique Dauge, E. Piat, Michaël Gauthier, Joël Abadie
    Abstract:

    This paper deals with the effective of smart microrobots for both Mechanical Cell characterization and Cell convoying for in vitro fertilization. The first microrobotic device was developed to evaluate oocyte Mechanical behavior in order to sort oocytes. A multi-axial micro-force sensor based on a frictionless magnetic bearing was developed. The second microrobotic device presented is a Cell convoying device consisting of a wireless micropusher based on magnetic actuation. As wireless capabilities are supported by this microrobotic system, no power supply connections to the micropusher are needed. Preliminary experiments have been performed regarding both Cell transporting and bioMechanical characterization capabilities under in vitro conditions on human oocytes so as to demonstrate the viability and effectiveness of the proposed setups.

Josiane Abadie - One of the best experts on this subject based on the ideXlab platform.

  • Smart microrobots for Mechanical Cell characterization and Cell convoying
    IEEE Transactions on Biomedical Engineering, 2007
    Co-Authors: Mehdi Boukallel, Michel Gauthier, Monique Dauge, E. Piat, Josiane Abadie
    Abstract:

    This paper deals with the effective design of smart microrobots for both Mechanical Cell characterization and Cell convoying for in vitro fertilization. The first microrobotic device was developed to evaluate oocyte Mechanical behavior in order to sort oocytes. A multi-axial micro-force sensor based on a frictionless magnetic bearing was developed. The second microrobotic device presented is a Cell convoying device consisting of a wireless micropusher based on magnetic actuation. As wireless capabilities are supported by this microrobotic system, no power supply connections to the micropusher are needed. Preliminary experiments have been performed regarding both Cell transporting and bioMechanical characterization capabilities under in vitro conditions on human oocytes so as to demonstrate the viability and effectiveness of the proposed setups.

Monique Dauge - One of the best experts on this subject based on the ideXlab platform.

  • Smart microrobots for Mechanical Cell characterization and Cell convoying.
    IEEE Transactions on Biomedical Engineering, 2007
    Co-Authors: Mehdi Boukallel, Monique Dauge, E. Piat, Michaël Gauthier, Joël Abadie
    Abstract:

    This paper deals with the effective of smart microrobots for both Mechanical Cell characterization and Cell convoying for in vitro fertilization. The first microrobotic device was developed to evaluate oocyte Mechanical behavior in order to sort oocytes. A multi-axial micro-force sensor based on a frictionless magnetic bearing was developed. The second microrobotic device presented is a Cell convoying device consisting of a wireless micropusher based on magnetic actuation. As wireless capabilities are supported by this microrobotic system, no power supply connections to the micropusher are needed. Preliminary experiments have been performed regarding both Cell transporting and bioMechanical characterization capabilities under in vitro conditions on human oocytes so as to demonstrate the viability and effectiveness of the proposed setups.

  • Smart microrobots for Mechanical Cell characterization and Cell convoying
    IEEE Transactions on Biomedical Engineering, 2007
    Co-Authors: Mehdi Boukallel, Michel Gauthier, Monique Dauge, E. Piat, Josiane Abadie
    Abstract:

    This paper deals with the effective design of smart microrobots for both Mechanical Cell characterization and Cell convoying for in vitro fertilization. The first microrobotic device was developed to evaluate oocyte Mechanical behavior in order to sort oocytes. A multi-axial micro-force sensor based on a frictionless magnetic bearing was developed. The second microrobotic device presented is a Cell convoying device consisting of a wireless micropusher based on magnetic actuation. As wireless capabilities are supported by this microrobotic system, no power supply connections to the micropusher are needed. Preliminary experiments have been performed regarding both Cell transporting and bioMechanical characterization capabilities under in vitro conditions on human oocytes so as to demonstrate the viability and effectiveness of the proposed setups.