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Werner Weber - One of the best experts on this subject based on the ideXlab platform.

  • complications of Mechanical Thrombectomy for acute ischemic stroke a retrospective single center study of 176 consecutive cases
    Neuroradiology, 2014
    Co-Authors: Daniel Behme, Ludger Gondecki, Sarah Fiethen, Annika Kowoll, Anastasios Mpotsaris, Werner Weber
    Abstract:

    Introduction There is only very limited data about complications in Mechanical Thrombectomy for acute ischemic stroke. The purpose of this study was to evaluate the frequency and the clinical relevance of procedure-related complications in Mechanical Thrombectomy.

  • Mechanical Thrombectomy in severe acute stroke preliminary results of the solitaire stent
    Journal of Neurology Neurosurgery and Psychiatry, 2012
    Co-Authors: Anastasios Mpotsaris, Matthias Bussmeyer, C Loehr, Michael Oelerich, Helmut Buchner, Werner Weber
    Abstract:

    Intravenous recombinant tissue plasminogen activator (rTPA) therapy has limited recanalisation-rates in large artery occlusions (nadir of 5.9% in Carotid-T-Occlusions).1 Therefore, we prospectively evaluated the Solitaire stent (versions AB and FR, ev3 Inc., Plymouth, Minnesota, USA) in Mechanical Thrombectomy in acute ischaemic stroke. Acute stroke patients were triaged on admission for potential Mechanical Thrombectomy. ### Inclusion criteria ### Exclusion criteria Eligible patients had immediate CT-angiography without delaying intravenous rTPA-thrombolysis if applicable according to the guidelines of the German Neurological Society (DGN). In case of occlusion of either the internal carotid artery (ICA), the MCA-M1-segment or the basilar artery (BA) Mechanical Thrombectomy was carried out. Up to four clot extraction maneuvers were performed. Any preceding stenosis was a priori stented. These patients received intravenous eptifibatide for 24 h to prevent in-stent-thrombosis; its short half-life would allow for emergency decompressive craniectomy. Combination of rTPA and eptifibatide is safe.2 NIHSS and mRS scores were assessed on admission and …

Sanjoy Nagaraja - One of the best experts on this subject based on the ideXlab platform.

  • Mechanical Thrombectomy for acute stroke in pregnancy
    The Neuroradiology Journal, 2020
    Co-Authors: Saminderjit Kular, Vartan Balian, Ramya Ram, George Tse, Stuart C. Coley, Shenaaz Jivraj, Sanjoy Nagaraja
    Abstract:

    Several recent randomised control trials have shown adjunctive endovascular Mechanical Thrombectomy to be an effective and safe treatment for acute stroke superior to medical therapy alone. Despite...

  • Foetal radiation exposure caused by Mechanical Thrombectomy in large-vessel ischaemic stroke in pregnancy
    Neuroradiology, 2019
    Co-Authors: Vartan Balian, Paraskevi Charalampatou, Paul Maliakal, Sanjeev Nayak, Richard Dyde, Sanjoy Nagaraja
    Abstract:

    Purpose There is overwhelming evidence for the clinical benefits that are derived following Mechanical Thrombectomy in large-vessel acute ischaemic stroke. The risk of stroke is elevated in pregnancy due to many factors. To date, there have been two reports, totalling five patients, who have undergone Mechanical Thrombectomy in pregnancy, thus demonstrating the feasibility of the procedure; however, there is no data on the radiation exposure to the mother or foetus related to this therapy. Methods We highlight the important technical considerations to minimise the risk of the procedure and report the estimated dose received by mother and foetus. We also compare these doses with those received during whole-body CT in trauma and CT pulmonary angiogram (CTPA) examinations. Results Three cases of Mechanical Thrombectomy were performed at separate tertiary referral neuroscience centres in the UK. Following diagnostic CT and Mechanical Thrombectomy, the total whole-body effective dose to the pregnant patient was significantly higher than in patients undergoing CTPA ( p  

  • Foetal radiation exposure caused by Mechanical Thrombectomy in large-vessel ischaemic stroke in pregnancy.
    Neuroradiology, 2019
    Co-Authors: George Tse, Vartan Balian, Paraskevi Charalampatou, Paul Maliakal, Sanjeev Nayak, Richard Dyde, Sanjoy Nagaraja
    Abstract:

    There is overwhelming evidence for the clinical benefits that are derived following Mechanical Thrombectomy in large-vessel acute ischaemic stroke. The risk of stroke is elevated in pregnancy due to many factors. To date, there have been two reports, totalling five patients, who have undergone Mechanical Thrombectomy in pregnancy, thus demonstrating the feasibility of the procedure; however, there is no data on the radiation exposure to the mother or foetus related to this therapy. We highlight the important technical considerations to minimise the risk of the procedure and report the estimated dose received by mother and foetus. We also compare these doses with those received during whole-body CT in trauma and CT pulmonary angiogram (CTPA) examinations. Three cases of Mechanical Thrombectomy were performed at separate tertiary referral neuroscience centres in the UK. Following diagnostic CT and Mechanical Thrombectomy, the total whole-body effective dose to the pregnant patient was significantly higher than in patients undergoing CTPA (p 

Jonathan M. Coutinho - One of the best experts on this subject based on the ideXlab platform.

  • Mechanical Thrombectomy in cerebral venous thrombosis systematic review of 185 cases
    Stroke, 2015
    Co-Authors: Jonathan M. Coutinho, Susanna M. Zuurbier, Jan Stam, Fazeel M Siddiqui, Sudeepta Dandapat, Chirantan Banerjee, Mark D Johnson
    Abstract:

    Background and Purpose—Cerebral venous thrombosis is generally treated with anticoagulation. However, some patients do not respond to medical therapy and these might benefit from Mechanical Thrombectomy. The aim of this study was to gain a better understanding of the efficacy and safety of Mechanical Thrombectomy in patients with cerebral venous thrombosis, by performing a systematic review of the literature. Methods—We identified studies published between January 1995 and February 2014 from PubMed and Ovid. We included all cases of cerebral venous thrombosis in whom Mechanical Thrombectomy was performed with or without intrasinus thrombolysis. Good outcome was defined as normal or mild neurological deficits at discharge (modified Rankin Scale, 0–2). Secondary outcome variables included periprocedural complications and recanalization rates. Results—Our study included 42 studies (185 patients). Sixty percent of patient had a pretreatment intracerebral hemorrhage and 47% were stuporous or comatose. AngioJet...

  • Mechanical Thrombectomy cannot be considered as first-line treatment for cerebral venous thrombosis.
    Journal of NeuroInterventional Surgery, 2012
    Co-Authors: Jonathan M. Coutinho, R. Van Den Berg, Susanna M. Zuurbier, Charles B. L. M. Majoie, Jan Stam
    Abstract:

    The paper by Dashti et al 1 describes 13 patients who received Mechanical Thrombectomy with the AngioJet device as first-line treatment for cerebral venous thrombosis (CVT). Mechanical Thrombectomy is a promising alternative to endovascular thrombolysis with thrombolytic drugs. Hemorrhagic infarcts are common among patients with CVT and it is plausible—although unproven—that Mechanical Thrombectomy gives fewer hemorrhagic complications. There are, however, some issues that render the authors' suggestion to use Mechanical Thrombectomy as a first-line treatment …

Anastasios Mpotsaris - One of the best experts on this subject based on the ideXlab platform.

  • complications of Mechanical Thrombectomy for acute ischemic stroke a retrospective single center study of 176 consecutive cases
    Neuroradiology, 2014
    Co-Authors: Daniel Behme, Ludger Gondecki, Sarah Fiethen, Annika Kowoll, Anastasios Mpotsaris, Werner Weber
    Abstract:

    Introduction There is only very limited data about complications in Mechanical Thrombectomy for acute ischemic stroke. The purpose of this study was to evaluate the frequency and the clinical relevance of procedure-related complications in Mechanical Thrombectomy.

  • Mechanical Thrombectomy in severe acute stroke preliminary results of the solitaire stent
    Journal of Neurology Neurosurgery and Psychiatry, 2012
    Co-Authors: Anastasios Mpotsaris, Matthias Bussmeyer, C Loehr, Michael Oelerich, Helmut Buchner, Werner Weber
    Abstract:

    Intravenous recombinant tissue plasminogen activator (rTPA) therapy has limited recanalisation-rates in large artery occlusions (nadir of 5.9% in Carotid-T-Occlusions).1 Therefore, we prospectively evaluated the Solitaire stent (versions AB and FR, ev3 Inc., Plymouth, Minnesota, USA) in Mechanical Thrombectomy in acute ischaemic stroke. Acute stroke patients were triaged on admission for potential Mechanical Thrombectomy. ### Inclusion criteria ### Exclusion criteria Eligible patients had immediate CT-angiography without delaying intravenous rTPA-thrombolysis if applicable according to the guidelines of the German Neurological Society (DGN). In case of occlusion of either the internal carotid artery (ICA), the MCA-M1-segment or the basilar artery (BA) Mechanical Thrombectomy was carried out. Up to four clot extraction maneuvers were performed. Any preceding stenosis was a priori stented. These patients received intravenous eptifibatide for 24 h to prevent in-stent-thrombosis; its short half-life would allow for emergency decompressive craniectomy. Combination of rTPA and eptifibatide is safe.2 NIHSS and mRS scores were assessed on admission and …

Vartan Balian - One of the best experts on this subject based on the ideXlab platform.

  • Mechanical Thrombectomy for acute stroke in pregnancy
    The Neuroradiology Journal, 2020
    Co-Authors: Saminderjit Kular, Vartan Balian, Ramya Ram, George Tse, Stuart C. Coley, Shenaaz Jivraj, Sanjoy Nagaraja
    Abstract:

    Several recent randomised control trials have shown adjunctive endovascular Mechanical Thrombectomy to be an effective and safe treatment for acute stroke superior to medical therapy alone. Despite...

  • Foetal radiation exposure caused by Mechanical Thrombectomy in large-vessel ischaemic stroke in pregnancy
    Neuroradiology, 2019
    Co-Authors: Vartan Balian, Paraskevi Charalampatou, Paul Maliakal, Sanjeev Nayak, Richard Dyde, Sanjoy Nagaraja
    Abstract:

    Purpose There is overwhelming evidence for the clinical benefits that are derived following Mechanical Thrombectomy in large-vessel acute ischaemic stroke. The risk of stroke is elevated in pregnancy due to many factors. To date, there have been two reports, totalling five patients, who have undergone Mechanical Thrombectomy in pregnancy, thus demonstrating the feasibility of the procedure; however, there is no data on the radiation exposure to the mother or foetus related to this therapy. Methods We highlight the important technical considerations to minimise the risk of the procedure and report the estimated dose received by mother and foetus. We also compare these doses with those received during whole-body CT in trauma and CT pulmonary angiogram (CTPA) examinations. Results Three cases of Mechanical Thrombectomy were performed at separate tertiary referral neuroscience centres in the UK. Following diagnostic CT and Mechanical Thrombectomy, the total whole-body effective dose to the pregnant patient was significantly higher than in patients undergoing CTPA ( p  

  • Foetal radiation exposure caused by Mechanical Thrombectomy in large-vessel ischaemic stroke in pregnancy.
    Neuroradiology, 2019
    Co-Authors: George Tse, Vartan Balian, Paraskevi Charalampatou, Paul Maliakal, Sanjeev Nayak, Richard Dyde, Sanjoy Nagaraja
    Abstract:

    There is overwhelming evidence for the clinical benefits that are derived following Mechanical Thrombectomy in large-vessel acute ischaemic stroke. The risk of stroke is elevated in pregnancy due to many factors. To date, there have been two reports, totalling five patients, who have undergone Mechanical Thrombectomy in pregnancy, thus demonstrating the feasibility of the procedure; however, there is no data on the radiation exposure to the mother or foetus related to this therapy. We highlight the important technical considerations to minimise the risk of the procedure and report the estimated dose received by mother and foetus. We also compare these doses with those received during whole-body CT in trauma and CT pulmonary angiogram (CTPA) examinations. Three cases of Mechanical Thrombectomy were performed at separate tertiary referral neuroscience centres in the UK. Following diagnostic CT and Mechanical Thrombectomy, the total whole-body effective dose to the pregnant patient was significantly higher than in patients undergoing CTPA (p