The Experts below are selected from a list of 30 Experts worldwide ranked by ideXlab platform

Öksüz M - One of the best experts on this subject based on the ideXlab platform.

  • Surgical repair of the isolated incomplete median cleft lip.
    'Elsevier BV', 2016
    Co-Authors: Topkara A, Özkan A, Öksüz M
    Abstract:

    Median cleft lip refers to a vertical cleft on the midline of the upper lip. It is a rare congenital craniofacial anomaly brought about by a fusion failure in the Medial Nasal Prominence. A novel surgical approach to median cleft lips and their repair is reported herein, with reference to a clinical case. The patient had a cleft in the lower half of the upper lip. There were no other craniofacial anomalies in this patient other than the cleft. Within the framework of the patient's surgical treatment, a functional and cosmetically satisfactory result was achieved by performing a V-Y advancement flap on the columella base, Z-plasty in the vermillion zone, and Z pattern muscular tissue repair, without having to resort to any tissue excisions

  • Surgical repair of the isolated incomplete median cleft lip
    'Elsevier BV', 2016
    Co-Authors: Topkara Adem, Özkan Adem, Özcan, Ramazan Hakan, Öksüz M
    Abstract:

    Median cleft lip refers to a vertical cleft on the midline of the upper lip. It is a rare congenital craniofacial anomaly brought about by a fusion failure in the Medial Nasal Prominence. A novel surgical approach to median cleft lips and their repair is reported herein, with reference to a clinical case. The patient had a cleft in the lower half of the upper lip. There were no other craniofacial anomalies in this patient other than the cleft. Within the framework of the patient's surgical treatment, a functional and cosmetically satisfactory result was achieved by performing a V–Y advancement flap on the columella base, Z-plasty in the vermillion zone, and Z pattern muscular tissue repair, without having to resort to any tissue excisions. © 2015 International Association of Oral and Maxillofacial Surgeon

Carol Wicking - One of the best experts on this subject based on the ideXlab platform.

  • Expression of Tmem26 in wild-type embryos by whole mount in situ hybridisation analysis.
    2013
    Co-Authors: Liam Town, Joy M. Richman, Edwina Mcglinn, Tara-lynne Davidson, Catherine M. Browne, Kallayanee Chawengsaksophak, Peter Koopman, Carol Wicking
    Abstract:

    (A–E) Whole embryos aged 11.0 dpc-14.5 dpc. No expression was detected before 11.0 dpc. (F–J) Forelimbs of corresponding embryos shown in A–E, dorsal view, limb anterior is to the top. (K,L) At 11.0 and 11.5 dpc Tmem26 expression in the facial Prominences is restricted primarily to mesenchyme underlying areas of facial Prominence fusion and merging. (M) At 12.5 dpc striking expression is observed in the primary palate, and expression remains at the midline of the mandible. (N) After fusion is complete at 13.5 dpc, expression is restricted to maxillary tissue at the distal tip of the snout. (O,P) The developing secondary palate at 14.5 dpc, taken from below with the mandible removed, one showing the palatal shelves wide apart, and one as the shelves are coming together to fuse. Tmem26 is expressed in the palatal shelves prior to fusion but downregulated upon palate fusion, most obvious at 15.5 dpc (Q). (R) Ventral and (S) lateral views of a 13.5 dpc genital tubercle. Dorsal-ventral and anterior-posterior axes are indicated. 1p-primary palate, 2p-secondary palatal shelves, e-external ear, em-extraoccular musculature, fl-forelimb, lnp-lateral Nasal Prominence, mes-Medial epithelial seam, md-mandible, mnp-Medial Nasal Prominence, mx-maxillary Prominence, n-Nasal opening, vcm-ventral cephalic mesenchyme.

  • Expression of Tmem26 in wild-type embryos by section in situ hybridisation.
    2013
    Co-Authors: Liam Town, Joy M. Richman, Edwina Mcglinn, Tara-lynne Davidson, Catherine M. Browne, Kallayanee Chawengsaksophak, Peter Koopman, Carol Wicking
    Abstract:

    (A–D, E–G,J) radioisotopic; (H,I) DIG detection. (A–D) Transverse sections through the secondary palate at indicated stages. At 12.5 dpc and 13.5 dpc Tmem26 is expressed in mesenchyme of the vertical palatal shelves. At 14.5 dpc the shelves have fused but the Medial epithelial seam still remains and expression within the mesenchyme is apparent. By 15.5 dpc the epithelial seam is absent and Tmem26 expression is virtually undetectable. (A′–D′) Corresponding serial sections stained with toluidine blue. (E–G) Sections through the facial Prominences and primary palate region at indicated stages. Tmem26 is not detected at 10.5 dpc but is upregulated at 11.5 dpc and 12.5 dpc. (E′–G′) Corresponding sections stained with toluidine blue. (H) Parasagittal section through the lateral hindbrain at 12.5 dpc, showing expression in the nucleus of the seventh facial nerve region within the pons. (I) Longitudinal section through the stomach at 11.5 dpc, showing expression in the anterior stomach mesenchyme. (J) Magnification of the left eyelid from D, (J′) same section counterstained with haematoxylin. 1p-primary palate, bt-mesencyme at the base of the tongue, c-cornea, el-eyelid, em-extraocular mesenchyme and developing extrinsic muscles of the eye, ep-epithelim, L-eye lens, lnp-lateral Nasal Prominence, n7-nucleus of the seventh facial nerve, mn-mandible, mnp-Medial Nasal Prominence, mx-maxillary Prominence, ns-Nasal septum, p-palatal shelf, pd-eyelid periderm, st-stomach mesenchyme. Size bars indicate 1 mm.

Topkara A - One of the best experts on this subject based on the ideXlab platform.

  • Surgical repair of the isolated incomplete median cleft lip.
    'Elsevier BV', 2016
    Co-Authors: Topkara A, Özkan A, Öksüz M
    Abstract:

    Median cleft lip refers to a vertical cleft on the midline of the upper lip. It is a rare congenital craniofacial anomaly brought about by a fusion failure in the Medial Nasal Prominence. A novel surgical approach to median cleft lips and their repair is reported herein, with reference to a clinical case. The patient had a cleft in the lower half of the upper lip. There were no other craniofacial anomalies in this patient other than the cleft. Within the framework of the patient's surgical treatment, a functional and cosmetically satisfactory result was achieved by performing a V-Y advancement flap on the columella base, Z-plasty in the vermillion zone, and Z pattern muscular tissue repair, without having to resort to any tissue excisions

Topkara Adem - One of the best experts on this subject based on the ideXlab platform.

  • Surgical repair of the isolated incomplete median cleft lip
    'Elsevier BV', 2016
    Co-Authors: Topkara Adem, Özkan Adem, Özcan, Ramazan Hakan, Öksüz M
    Abstract:

    Median cleft lip refers to a vertical cleft on the midline of the upper lip. It is a rare congenital craniofacial anomaly brought about by a fusion failure in the Medial Nasal Prominence. A novel surgical approach to median cleft lips and their repair is reported herein, with reference to a clinical case. The patient had a cleft in the lower half of the upper lip. There were no other craniofacial anomalies in this patient other than the cleft. Within the framework of the patient's surgical treatment, a functional and cosmetically satisfactory result was achieved by performing a V–Y advancement flap on the columella base, Z-plasty in the vermillion zone, and Z pattern muscular tissue repair, without having to resort to any tissue excisions. © 2015 International Association of Oral and Maxillofacial Surgeon

Liam Town - One of the best experts on this subject based on the ideXlab platform.

  • Expression of Tmem26 in wild-type embryos by whole mount in situ hybridisation analysis.
    2013
    Co-Authors: Liam Town, Joy M. Richman, Edwina Mcglinn, Tara-lynne Davidson, Catherine M. Browne, Kallayanee Chawengsaksophak, Peter Koopman, Carol Wicking
    Abstract:

    (A–E) Whole embryos aged 11.0 dpc-14.5 dpc. No expression was detected before 11.0 dpc. (F–J) Forelimbs of corresponding embryos shown in A–E, dorsal view, limb anterior is to the top. (K,L) At 11.0 and 11.5 dpc Tmem26 expression in the facial Prominences is restricted primarily to mesenchyme underlying areas of facial Prominence fusion and merging. (M) At 12.5 dpc striking expression is observed in the primary palate, and expression remains at the midline of the mandible. (N) After fusion is complete at 13.5 dpc, expression is restricted to maxillary tissue at the distal tip of the snout. (O,P) The developing secondary palate at 14.5 dpc, taken from below with the mandible removed, one showing the palatal shelves wide apart, and one as the shelves are coming together to fuse. Tmem26 is expressed in the palatal shelves prior to fusion but downregulated upon palate fusion, most obvious at 15.5 dpc (Q). (R) Ventral and (S) lateral views of a 13.5 dpc genital tubercle. Dorsal-ventral and anterior-posterior axes are indicated. 1p-primary palate, 2p-secondary palatal shelves, e-external ear, em-extraoccular musculature, fl-forelimb, lnp-lateral Nasal Prominence, mes-Medial epithelial seam, md-mandible, mnp-Medial Nasal Prominence, mx-maxillary Prominence, n-Nasal opening, vcm-ventral cephalic mesenchyme.

  • Expression of Tmem26 in wild-type embryos by section in situ hybridisation.
    2013
    Co-Authors: Liam Town, Joy M. Richman, Edwina Mcglinn, Tara-lynne Davidson, Catherine M. Browne, Kallayanee Chawengsaksophak, Peter Koopman, Carol Wicking
    Abstract:

    (A–D, E–G,J) radioisotopic; (H,I) DIG detection. (A–D) Transverse sections through the secondary palate at indicated stages. At 12.5 dpc and 13.5 dpc Tmem26 is expressed in mesenchyme of the vertical palatal shelves. At 14.5 dpc the shelves have fused but the Medial epithelial seam still remains and expression within the mesenchyme is apparent. By 15.5 dpc the epithelial seam is absent and Tmem26 expression is virtually undetectable. (A′–D′) Corresponding serial sections stained with toluidine blue. (E–G) Sections through the facial Prominences and primary palate region at indicated stages. Tmem26 is not detected at 10.5 dpc but is upregulated at 11.5 dpc and 12.5 dpc. (E′–G′) Corresponding sections stained with toluidine blue. (H) Parasagittal section through the lateral hindbrain at 12.5 dpc, showing expression in the nucleus of the seventh facial nerve region within the pons. (I) Longitudinal section through the stomach at 11.5 dpc, showing expression in the anterior stomach mesenchyme. (J) Magnification of the left eyelid from D, (J′) same section counterstained with haematoxylin. 1p-primary palate, bt-mesencyme at the base of the tongue, c-cornea, el-eyelid, em-extraocular mesenchyme and developing extrinsic muscles of the eye, ep-epithelim, L-eye lens, lnp-lateral Nasal Prominence, n7-nucleus of the seventh facial nerve, mn-mandible, mnp-Medial Nasal Prominence, mx-maxillary Prominence, ns-Nasal septum, p-palatal shelf, pd-eyelid periderm, st-stomach mesenchyme. Size bars indicate 1 mm.