The Experts below are selected from a list of 48 Experts worldwide ranked by ideXlab platform
Si-chen Lee - One of the best experts on this subject based on the ideXlab platform.
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All-printed paper memory.
ACS nano, 2014Co-Authors: Der-hsien Lien, Zhen-kai Kao, Teng-han Huang, Ying-chih Liao, Si-chen LeeAbstract:We report the memory device on paper by means of an all-printing approach. Using a sequence of inkjet and screen-printing techniques, a simple metal–insulator–metal device structure is fabricated on paper as a resistive random access memory with a potential to reach gigabyte capacities on an A4 paper. The printed-paper-based memory devices (PPMDs) exhibit reproducible switching endurance, reliable retention, tunable memory window, and the capability to operate under extreme bending conditions. In addition, the PBMD can be labeled on electronics or living objects for multifunctional, wearable, on-skin, and biocompatible applications. The disposability and the high-security data storage of the paper-based memory are also demonstrated to show the ease of data handling, which are not achievable for regular silicon-based electronic devices. We envision that the PPMDs manufactured by this cost-effective and time-efficient all-printing approach would be a key electronic component to fully activate a paper-based circuit and can be directly implemented in Medical Biosensors, multifunctional devices, and self-powered systems.
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Paper memory by all printing technology
2014 Symposium on VLSI Technology (VLSI-Technology): Digest of Technical Papers, 2014Co-Authors: Der-hsien Lien, Teng-han Huang, Ying-chih Liao, Zhen Kai Kuo, Si-chen LeeAbstract:We report the first paper-based nonvolatile memory device by means of an all-printing approach using a sequence of inkjet and screen printing techniques to fabricate a resistive random access memory on paper. The printed paper-based memory devices (PPMDs) can be labeled on electronics or living objects for multi-functional, wearable, on-skin, and biocompatible applications. The PPMDs would be a key electronic component to fully activate a paper-based circuit and can be directly implemented in Medical Biosensors, multi-functional devices, and self-powered systems.
Noemi Rozlosnik - One of the best experts on this subject based on the ideXlab platform.
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New directions in Medical Biosensors employing poly(3,4-ethylenedioxy thiophene) derivative-based electrodes
Analytical and Bioanalytical Chemistry, 2009Co-Authors: Noemi RozlosnikAbstract:Demand is growing in the field of Medical diagnostics for simple, disposable devices that also demonstrate fast response times, are easy to handle, are cost-efficient, and are suitable for mass production. Polymer-based microfluidic devices meet the requirements of cost efficiency and mass production and they are suitable for biosensor applications. Conducting polymer-based electrochemical sensors have shown numerous advantages in a number of areas related to human health, such as the diagnosis of infectious diseases, genetic mutations, drug discovery, forensics and food technology, due to their simplicity and high sensitivity. One of the most promising group of conductive polymers is poly(3,4-ethylenedioxythiophene) (PEDOT) and its derivatives due to their attractive properties: high stability, high conductivity (up to 400-600 S/cm) and high transparency. This review paper summarizes newly developed methods associated with the application of PEDOT to diagnostic sensing.
Der-hsien Lien - One of the best experts on this subject based on the ideXlab platform.
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All-printed paper memory.
ACS nano, 2014Co-Authors: Der-hsien Lien, Zhen-kai Kao, Teng-han Huang, Ying-chih Liao, Si-chen LeeAbstract:We report the memory device on paper by means of an all-printing approach. Using a sequence of inkjet and screen-printing techniques, a simple metal–insulator–metal device structure is fabricated on paper as a resistive random access memory with a potential to reach gigabyte capacities on an A4 paper. The printed-paper-based memory devices (PPMDs) exhibit reproducible switching endurance, reliable retention, tunable memory window, and the capability to operate under extreme bending conditions. In addition, the PBMD can be labeled on electronics or living objects for multifunctional, wearable, on-skin, and biocompatible applications. The disposability and the high-security data storage of the paper-based memory are also demonstrated to show the ease of data handling, which are not achievable for regular silicon-based electronic devices. We envision that the PPMDs manufactured by this cost-effective and time-efficient all-printing approach would be a key electronic component to fully activate a paper-based circuit and can be directly implemented in Medical Biosensors, multifunctional devices, and self-powered systems.
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Paper memory by all printing technology
2014 Symposium on VLSI Technology (VLSI-Technology): Digest of Technical Papers, 2014Co-Authors: Der-hsien Lien, Teng-han Huang, Ying-chih Liao, Zhen Kai Kuo, Si-chen LeeAbstract:We report the first paper-based nonvolatile memory device by means of an all-printing approach using a sequence of inkjet and screen printing techniques to fabricate a resistive random access memory on paper. The printed paper-based memory devices (PPMDs) can be labeled on electronics or living objects for multi-functional, wearable, on-skin, and biocompatible applications. The PPMDs would be a key electronic component to fully activate a paper-based circuit and can be directly implemented in Medical Biosensors, multi-functional devices, and self-powered systems.
V. V. Shumyantseva - One of the best experts on this subject based on the ideXlab platform.
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Cytochrome P450 3A4 as a Drug Metabolizing Enzyme: the Role of Sensor System Modifications in Electocatalysis and Electroanalysis
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry, 2020Co-Authors: A. V. Kuzikov, T. V. Bulko, P. I. Koroleva, R. A. Masamrekh, S. S. Babkina, A. A. Gilep, V. V. ShumyantsevaAbstract:The electroanalytical characteristics of the recombinant cytochrome P450 3A4 (CYP3A4) immobilized on the surface of screen-printed graphite electrodes modified by multi-walled carbon nanotubes (MWCNTs) have been investigated. The role and the influence of the modification of a graphite working electrode by carbon nanotubes on the electroanalytical parameters of this cytochrome have been demonstrated. The conditions for its immobilization on the obtained screen-printed graphite electrodes modified by MWCNTs have been optimized. The electrochemical parameters of the oxidation and reduction of the enzyme heme iron ion were determined: these included midpoint-potential ( E ^0') of –0.35 ± 0.01 V (relative to the silver/silver chloride reference electrode, Ag/AgCl); the electrochemical rate constant of heterogeneous electron transfer ( k _s) of 0.57 ± 0.04 s^–1, the amount of electroactive CYP3A4 on the modified electrode (Γ_0) of (2.6 ± 0.6) × 10^–10 mol/cm^2. The functioning mechanism of this electrochemical sensor followed the principle of “protein film voltammetry” (i.e. voltammetry of a protein film on the electrode surface). In order to develop Medical Biosensors using immobilized CYP3A4 for electroanalysis of drug substances, the substrates of this hemoprotein, we performed a voltammetric study of the catalytic activity of immobilized CYP3A4. We investigated electrocatalytic properties of the recombinant CYP3A4 immobilized on modified screen-printed graphite electrode using macrolide antibiotic erythromycin as a substrate. The modification of electrodes has been shown to play a decisive role for the study of the properties of cytochromes P450 in electrochemical studies. Smart electrodes can serve as electroanalyzers for analytical purposes, as well as electrocatalysts for the study of biotransformation and metabolic processes. Electrodes modified with carbon nanomaterials are applicable for analytical purposes in the registration of hemoproteins. Electrodes modified with synthetic membrane-like compounds (for example, didodecyldimethylammonium bromide) are effective in enzyme-dependent electrocatalysis.
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Electroanalytical and electrocatalytical characteristics of cytochrome P450 3A4 using electrodes modified with nanocomposite carbon nanomaterials
Biomeditsinskaia khimiia, 2020Co-Authors: A. V. Kuzikov, T. V. Bulko, P. I. Koroleva, R. A. Masamrekh, S. S. Babkina, A. A. Gilep, V. V. ShumyantsevaAbstract:The electroanalytical characteristics of recombinant cytochrome P450 3A4 (P450 3A4) immobilized on the surface of screen-printed graphite electrodes modified with multi-walled carbon nanotubes have been studied. The role and the influence of graphite working electrode modification with carbon nanotubes on electroanalytical characteristics of cytochrome P450 3A4 have been demonstrated. The conditions for the immobilization of cytochrome P450 3A4 on the obtained screen-printed graphite electrodes modified with carbon multi-walled nanotubes have been optimized. The electrochemical parameters of the oxidation and reduction of the heme iron of the enzyme have been estimated. The midpoint potential E0' was -0.35±0.01 V vs Ag/AgCl; the calculated heterogeneous electron transfer rate constant ks, was 0.57±0.04 s-1; the amount of electroactive cytochrome P450 3A4 on the electrode Г0, was determined as (2.6±0.6)⋅10-10 mol/cm2. The functioning mechanism of P450 3A4-based electrochemical sensor followed the "protein film voltammetry". In order to develop electrochemical analysis of drugs being substrates of that hemoprotein and respective Medical Biosensors the voltammetric study of catalytic activity of immobilized cytochrome P450 3A4 was carried out. Electrocatalytic properties of cytochrome P450 3A4, immobilized on modified screen-printed graphite electrodes, has been investigated using erythromycin (macrolide antibiotics). It has been shown that the modification of electrodes plays a decisive role for the study of the properties of cytochromes P450 in electrochemical investigations. Smart electrodes can serve as sensors for analytical purposes, as well as electrocatalysts for the study of biotransformation processes and metabolic processes. Electrodes modified with carbon nanomaterials are applicable for analytical purposes in the registration of hemoproteins. Electrodes modified with synthetic membrane-like compounds (e.g. didodecyldimethylammonium bromide) are effective in enzyme-dependent electrocatalysis.
Teng-han Huang - One of the best experts on this subject based on the ideXlab platform.
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All-printed paper memory.
ACS nano, 2014Co-Authors: Der-hsien Lien, Zhen-kai Kao, Teng-han Huang, Ying-chih Liao, Si-chen LeeAbstract:We report the memory device on paper by means of an all-printing approach. Using a sequence of inkjet and screen-printing techniques, a simple metal–insulator–metal device structure is fabricated on paper as a resistive random access memory with a potential to reach gigabyte capacities on an A4 paper. The printed-paper-based memory devices (PPMDs) exhibit reproducible switching endurance, reliable retention, tunable memory window, and the capability to operate under extreme bending conditions. In addition, the PBMD can be labeled on electronics or living objects for multifunctional, wearable, on-skin, and biocompatible applications. The disposability and the high-security data storage of the paper-based memory are also demonstrated to show the ease of data handling, which are not achievable for regular silicon-based electronic devices. We envision that the PPMDs manufactured by this cost-effective and time-efficient all-printing approach would be a key electronic component to fully activate a paper-based circuit and can be directly implemented in Medical Biosensors, multifunctional devices, and self-powered systems.
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Paper memory by all printing technology
2014 Symposium on VLSI Technology (VLSI-Technology): Digest of Technical Papers, 2014Co-Authors: Der-hsien Lien, Teng-han Huang, Ying-chih Liao, Zhen Kai Kuo, Si-chen LeeAbstract:We report the first paper-based nonvolatile memory device by means of an all-printing approach using a sequence of inkjet and screen printing techniques to fabricate a resistive random access memory on paper. The printed paper-based memory devices (PPMDs) can be labeled on electronics or living objects for multi-functional, wearable, on-skin, and biocompatible applications. The PPMDs would be a key electronic component to fully activate a paper-based circuit and can be directly implemented in Medical Biosensors, multi-functional devices, and self-powered systems.