Meglumine

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Ulrike I. Attenberger - One of the best experts on this subject based on the ideXlab platform.

  • Enhancement Characteristics and Impact on Image Quality of Two Gadolinium Chelates at Equimolar Doses for Time-Resolved 3-Tesla MR-Angiography of the Calf Station
    2016
    Co-Authors: Henrik J. Michaely, John N. Morelli, Stefan O. Schoenberg, André Luckscheiter, Ulrike I. Attenberger
    Abstract:

    Purpose: To compare enhancement characteristics and image quality of two macrocyclic gadolinium chelates, gadoterate Meglumine and gadobutrol, in low-dose, time-resolved MRA of the calf station. Materials and Methods: 100 consecutive patients with peripheral arterial disease (stages II-IV) were retrospectively analysed. Fifty patients were included in each group- 32 men and 18 women for gadobutrol (mean age 67 years) and 34 men, 16 women for gadoterate Meglumine (mean age 64 years). 0.03 mmol/kg bw of either gadobutrol or gadoterate Meglumine was injected. Gadobutrol was diluted 1:1 with normal saline (0.9 % NaCl) to provide similar injection volume and bolus geometry compared to the undiluted 0.5 M dose of gadoterate Meglumine. Signal-to-noise-ratio (SNR), contrast-to-noise-ratio (CNR) and image quality were analysed and compared between the two groups. Results: Mean SNR ranged from 83.0646.7 (peroneal artery) to 96.4664.5 (anterior tibial artery) for gadobutrol, and from 37.6613.8 (peroneal artery) to 45.3616.4 (anterior tibial artery) for the gadoterate Meglumine group (p,0.0001). CNR values ranged from 30.1620.1 (peroneal artery) to 37.6626.0 (anterior tibial artery) for gadobutrol and from 14.968.0 (peroneal artery) to 18.6616.4 (anterior tibial artery) for gadoterate Meglumine (p,0.0001). No significant difference in image quality was found except for the peroneal arteries (p = 0.006 and p = 0.04). Interreader agreement was excellent (kappa 0.87–0.93

  • Enhancement characteristics and impact on image quality of two gadolinium chelates at equimolar doses for time-resolved 3-Tesla MR-angiography of the calf station.
    PLoS ONE, 2014
    Co-Authors: Jan Hansmann, John N. Morelli, Henrik J. Michaely, Stefan O. Schoenberg, André Luckscheiter, Ulrike I. Attenberger
    Abstract:

    PURPOSE To compare enhancement characteristics and image quality of two macrocyclic gadolinium chelates, gadoterate Meglumine and gadobutrol, in low-dose, time-resolved MRA of the calf station. MATERIALS AND METHODS 100 consecutive patients with peripheral arterial disease (stages II-IV) were retrospectively analysed. Fifty patients were included in each group - 32 men and 18 women for gadobutrol (mean age 67 years) and 34 men, 16 women for gadoterate Meglumine (mean age 64 years). 0.03 mmol/kg bw of either gadobutrol or gadoterate Meglumine was injected. Gadobutrol was diluted 1 ∶ 1 with normal saline (0.9% NaCl) to provide similar injection volume and bolus geometry compared to the undiluted 0.5 M dose of gadoterate Meglumine. Signal-to-noise-ratio (SNR), contrast-to-noise-ratio (CNR) and image quality were analysed and compared between the two groups. RESULTS Mean SNR ranged from 83.0 ± 46.7 (peroneal artery) to 96.4 ± 64.5 (anterior tibial artery) for gadobutrol, and from 37.6 ± 13.8 (peroneal artery) to 45.3 ± 16.4 (anterior tibial artery) for the gadoterate Meglumine group (p

Jan Hansmann - One of the best experts on this subject based on the ideXlab platform.

  • Enhancement characteristics and impact on image quality of two gadolinium chelates at equimolar doses for time-resolved 3-Tesla MR-angiography of the calf station.
    PLoS ONE, 2014
    Co-Authors: Jan Hansmann, John N. Morelli, Henrik J. Michaely, Stefan O. Schoenberg, André Luckscheiter, Ulrike I. Attenberger
    Abstract:

    PURPOSE To compare enhancement characteristics and image quality of two macrocyclic gadolinium chelates, gadoterate Meglumine and gadobutrol, in low-dose, time-resolved MRA of the calf station. MATERIALS AND METHODS 100 consecutive patients with peripheral arterial disease (stages II-IV) were retrospectively analysed. Fifty patients were included in each group - 32 men and 18 women for gadobutrol (mean age 67 years) and 34 men, 16 women for gadoterate Meglumine (mean age 64 years). 0.03 mmol/kg bw of either gadobutrol or gadoterate Meglumine was injected. Gadobutrol was diluted 1 ∶ 1 with normal saline (0.9% NaCl) to provide similar injection volume and bolus geometry compared to the undiluted 0.5 M dose of gadoterate Meglumine. Signal-to-noise-ratio (SNR), contrast-to-noise-ratio (CNR) and image quality were analysed and compared between the two groups. RESULTS Mean SNR ranged from 83.0 ± 46.7 (peroneal artery) to 96.4 ± 64.5 (anterior tibial artery) for gadobutrol, and from 37.6 ± 13.8 (peroneal artery) to 45.3 ± 16.4 (anterior tibial artery) for the gadoterate Meglumine group (p

Henrik J. Michaely - One of the best experts on this subject based on the ideXlab platform.

  • Enhancement Characteristics and Impact on Image Quality of Two Gadolinium Chelates at Equimolar Doses for Time-Resolved 3-Tesla MR-Angiography of the Calf Station
    2016
    Co-Authors: Henrik J. Michaely, John N. Morelli, Stefan O. Schoenberg, André Luckscheiter, Ulrike I. Attenberger
    Abstract:

    Purpose: To compare enhancement characteristics and image quality of two macrocyclic gadolinium chelates, gadoterate Meglumine and gadobutrol, in low-dose, time-resolved MRA of the calf station. Materials and Methods: 100 consecutive patients with peripheral arterial disease (stages II-IV) were retrospectively analysed. Fifty patients were included in each group- 32 men and 18 women for gadobutrol (mean age 67 years) and 34 men, 16 women for gadoterate Meglumine (mean age 64 years). 0.03 mmol/kg bw of either gadobutrol or gadoterate Meglumine was injected. Gadobutrol was diluted 1:1 with normal saline (0.9 % NaCl) to provide similar injection volume and bolus geometry compared to the undiluted 0.5 M dose of gadoterate Meglumine. Signal-to-noise-ratio (SNR), contrast-to-noise-ratio (CNR) and image quality were analysed and compared between the two groups. Results: Mean SNR ranged from 83.0646.7 (peroneal artery) to 96.4664.5 (anterior tibial artery) for gadobutrol, and from 37.6613.8 (peroneal artery) to 45.3616.4 (anterior tibial artery) for the gadoterate Meglumine group (p,0.0001). CNR values ranged from 30.1620.1 (peroneal artery) to 37.6626.0 (anterior tibial artery) for gadobutrol and from 14.968.0 (peroneal artery) to 18.6616.4 (anterior tibial artery) for gadoterate Meglumine (p,0.0001). No significant difference in image quality was found except for the peroneal arteries (p = 0.006 and p = 0.04). Interreader agreement was excellent (kappa 0.87–0.93

  • Enhancement characteristics and impact on image quality of two gadolinium chelates at equimolar doses for time-resolved 3-Tesla MR-angiography of the calf station.
    PLoS ONE, 2014
    Co-Authors: Jan Hansmann, John N. Morelli, Henrik J. Michaely, Stefan O. Schoenberg, André Luckscheiter, Ulrike I. Attenberger
    Abstract:

    PURPOSE To compare enhancement characteristics and image quality of two macrocyclic gadolinium chelates, gadoterate Meglumine and gadobutrol, in low-dose, time-resolved MRA of the calf station. MATERIALS AND METHODS 100 consecutive patients with peripheral arterial disease (stages II-IV) were retrospectively analysed. Fifty patients were included in each group - 32 men and 18 women for gadobutrol (mean age 67 years) and 34 men, 16 women for gadoterate Meglumine (mean age 64 years). 0.03 mmol/kg bw of either gadobutrol or gadoterate Meglumine was injected. Gadobutrol was diluted 1 ∶ 1 with normal saline (0.9% NaCl) to provide similar injection volume and bolus geometry compared to the undiluted 0.5 M dose of gadoterate Meglumine. Signal-to-noise-ratio (SNR), contrast-to-noise-ratio (CNR) and image quality were analysed and compared between the two groups. RESULTS Mean SNR ranged from 83.0 ± 46.7 (peroneal artery) to 96.4 ± 64.5 (anterior tibial artery) for gadobutrol, and from 37.6 ± 13.8 (peroneal artery) to 45.3 ± 16.4 (anterior tibial artery) for the gadoterate Meglumine group (p

John N. Morelli - One of the best experts on this subject based on the ideXlab platform.

  • Enhancement Characteristics and Impact on Image Quality of Two Gadolinium Chelates at Equimolar Doses for Time-Resolved 3-Tesla MR-Angiography of the Calf Station
    2016
    Co-Authors: Henrik J. Michaely, John N. Morelli, Stefan O. Schoenberg, André Luckscheiter, Ulrike I. Attenberger
    Abstract:

    Purpose: To compare enhancement characteristics and image quality of two macrocyclic gadolinium chelates, gadoterate Meglumine and gadobutrol, in low-dose, time-resolved MRA of the calf station. Materials and Methods: 100 consecutive patients with peripheral arterial disease (stages II-IV) were retrospectively analysed. Fifty patients were included in each group- 32 men and 18 women for gadobutrol (mean age 67 years) and 34 men, 16 women for gadoterate Meglumine (mean age 64 years). 0.03 mmol/kg bw of either gadobutrol or gadoterate Meglumine was injected. Gadobutrol was diluted 1:1 with normal saline (0.9 % NaCl) to provide similar injection volume and bolus geometry compared to the undiluted 0.5 M dose of gadoterate Meglumine. Signal-to-noise-ratio (SNR), contrast-to-noise-ratio (CNR) and image quality were analysed and compared between the two groups. Results: Mean SNR ranged from 83.0646.7 (peroneal artery) to 96.4664.5 (anterior tibial artery) for gadobutrol, and from 37.6613.8 (peroneal artery) to 45.3616.4 (anterior tibial artery) for the gadoterate Meglumine group (p,0.0001). CNR values ranged from 30.1620.1 (peroneal artery) to 37.6626.0 (anterior tibial artery) for gadobutrol and from 14.968.0 (peroneal artery) to 18.6616.4 (anterior tibial artery) for gadoterate Meglumine (p,0.0001). No significant difference in image quality was found except for the peroneal arteries (p = 0.006 and p = 0.04). Interreader agreement was excellent (kappa 0.87–0.93

  • Enhancement characteristics and impact on image quality of two gadolinium chelates at equimolar doses for time-resolved 3-Tesla MR-angiography of the calf station.
    PLoS ONE, 2014
    Co-Authors: Jan Hansmann, John N. Morelli, Henrik J. Michaely, Stefan O. Schoenberg, André Luckscheiter, Ulrike I. Attenberger
    Abstract:

    PURPOSE To compare enhancement characteristics and image quality of two macrocyclic gadolinium chelates, gadoterate Meglumine and gadobutrol, in low-dose, time-resolved MRA of the calf station. MATERIALS AND METHODS 100 consecutive patients with peripheral arterial disease (stages II-IV) were retrospectively analysed. Fifty patients were included in each group - 32 men and 18 women for gadobutrol (mean age 67 years) and 34 men, 16 women for gadoterate Meglumine (mean age 64 years). 0.03 mmol/kg bw of either gadobutrol or gadoterate Meglumine was injected. Gadobutrol was diluted 1 ∶ 1 with normal saline (0.9% NaCl) to provide similar injection volume and bolus geometry compared to the undiluted 0.5 M dose of gadoterate Meglumine. Signal-to-noise-ratio (SNR), contrast-to-noise-ratio (CNR) and image quality were analysed and compared between the two groups. RESULTS Mean SNR ranged from 83.0 ± 46.7 (peroneal artery) to 96.4 ± 64.5 (anterior tibial artery) for gadobutrol, and from 37.6 ± 13.8 (peroneal artery) to 45.3 ± 16.4 (anterior tibial artery) for the gadoterate Meglumine group (p

André Luckscheiter - One of the best experts on this subject based on the ideXlab platform.

  • Enhancement Characteristics and Impact on Image Quality of Two Gadolinium Chelates at Equimolar Doses for Time-Resolved 3-Tesla MR-Angiography of the Calf Station
    2016
    Co-Authors: Henrik J. Michaely, John N. Morelli, Stefan O. Schoenberg, André Luckscheiter, Ulrike I. Attenberger
    Abstract:

    Purpose: To compare enhancement characteristics and image quality of two macrocyclic gadolinium chelates, gadoterate Meglumine and gadobutrol, in low-dose, time-resolved MRA of the calf station. Materials and Methods: 100 consecutive patients with peripheral arterial disease (stages II-IV) were retrospectively analysed. Fifty patients were included in each group- 32 men and 18 women for gadobutrol (mean age 67 years) and 34 men, 16 women for gadoterate Meglumine (mean age 64 years). 0.03 mmol/kg bw of either gadobutrol or gadoterate Meglumine was injected. Gadobutrol was diluted 1:1 with normal saline (0.9 % NaCl) to provide similar injection volume and bolus geometry compared to the undiluted 0.5 M dose of gadoterate Meglumine. Signal-to-noise-ratio (SNR), contrast-to-noise-ratio (CNR) and image quality were analysed and compared between the two groups. Results: Mean SNR ranged from 83.0646.7 (peroneal artery) to 96.4664.5 (anterior tibial artery) for gadobutrol, and from 37.6613.8 (peroneal artery) to 45.3616.4 (anterior tibial artery) for the gadoterate Meglumine group (p,0.0001). CNR values ranged from 30.1620.1 (peroneal artery) to 37.6626.0 (anterior tibial artery) for gadobutrol and from 14.968.0 (peroneal artery) to 18.6616.4 (anterior tibial artery) for gadoterate Meglumine (p,0.0001). No significant difference in image quality was found except for the peroneal arteries (p = 0.006 and p = 0.04). Interreader agreement was excellent (kappa 0.87–0.93

  • Enhancement characteristics and impact on image quality of two gadolinium chelates at equimolar doses for time-resolved 3-Tesla MR-angiography of the calf station.
    PLoS ONE, 2014
    Co-Authors: Jan Hansmann, John N. Morelli, Henrik J. Michaely, Stefan O. Schoenberg, André Luckscheiter, Ulrike I. Attenberger
    Abstract:

    PURPOSE To compare enhancement characteristics and image quality of two macrocyclic gadolinium chelates, gadoterate Meglumine and gadobutrol, in low-dose, time-resolved MRA of the calf station. MATERIALS AND METHODS 100 consecutive patients with peripheral arterial disease (stages II-IV) were retrospectively analysed. Fifty patients were included in each group - 32 men and 18 women for gadobutrol (mean age 67 years) and 34 men, 16 women for gadoterate Meglumine (mean age 64 years). 0.03 mmol/kg bw of either gadobutrol or gadoterate Meglumine was injected. Gadobutrol was diluted 1 ∶ 1 with normal saline (0.9% NaCl) to provide similar injection volume and bolus geometry compared to the undiluted 0.5 M dose of gadoterate Meglumine. Signal-to-noise-ratio (SNR), contrast-to-noise-ratio (CNR) and image quality were analysed and compared between the two groups. RESULTS Mean SNR ranged from 83.0 ± 46.7 (peroneal artery) to 96.4 ± 64.5 (anterior tibial artery) for gadobutrol, and from 37.6 ± 13.8 (peroneal artery) to 45.3 ± 16.4 (anterior tibial artery) for the gadoterate Meglumine group (p

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