The Experts below are selected from a list of 360 Experts worldwide ranked by ideXlab platform

Shomron Ben-horin - One of the best experts on this subject based on the ideXlab platform.

  • Clinical and radiographic presentation of superior Mesenteric Vein Thrombosis in Crohn's disease: A single center experience
    Journal of Crohn's & colitis, 2011
    Co-Authors: Uri Kopylov, Marianne M. Amitai, Aharon Lubetsky, Rami Eliakim, Yehuda Chowers, Shomron Ben-horin
    Abstract:

    Abstract Background Mesenteric Vein Thrombosis (MVT) is a rare and frequently underdiagnosed complicationof Crohn's disease (CD). This study describes the clinical and radiological characteristics of CD /patients with superior Mesenteric Vein Thrombosis (MVT) diagnosed by CT/MRI. Patients and methods The database of Crohn's disease patients treated in Sheba Medical Center between 2005-2010 was searched for MVT diagnosis. Imaging studies of identified patients were retrieved and reviewed by an experienced abdominal radiologist. MVT was defined by superior Mesenteric Vein obliteration and/or thrombus in the vessel lumen on abdominal imaging. The clinical and radiologic data of these patients were collected from the medical records. Results MVT was demonstrated in 6/460 CD patients. Five patients had stricturing disease, and one patient had a combined fistulizing and stricturing disease phenotype. All patients had small bowel disease, but 3/6 also had colonic involvement. No patient had a prior thromboembolic history or demonstrable hypercoagulability. One patient had an acute SMV thrombus demonstrable on CT scanning, the remaining patients showed an obliteration of superior Mesenteric Vein. Two patients received anticoagulation upon diagnosis of Thrombosis. No subsequent thromboembolic events were recorded. Conclusions The incidence of Mesenteric Vein Thrombosis is likely to be underestimated in patients with Crohn’s disease. Both CT and MRI imaging demonstrate the extent of enteric disease and coincident SMV Thrombosis. In our cohort, Thrombosis was associated with stricturing disease of the small bowel. The clinical impact of SMV Thrombosis and whether anticoagulation is mandatory for all of these patients remains to be determined.

Nuno Dias - One of the best experts on this subject based on the ideXlab platform.

M Verhamme - One of the best experts on this subject based on the ideXlab platform.

  • cytomegalovirus associated superior Mesenteric Vein Thrombosis treated with systemic and in situ thrombolysis
    European Journal of Gastroenterology & Hepatology, 2009
    Co-Authors: Wouter Van Moerkercke, Karen Pauwelyn, Eddy Maurice Paul Brugman, M Verhamme
    Abstract:

    A 56-year-old patient, first diagnosed with an acute cytomegalovirus infection, presented with progressive abdominal pain because of a superior Mesenteric Vein Thrombosis for which he was treated with systemic thrombolysis and heparin in continuous infusion. As this therapy did not have the intended success after 5 days, an interventional radiological procedure was performed with local thrombolysis in the superior Mesenteric artery resulting in recanalisation of the Vein. Oral anticoagulation was initiated and continued for a period of 6 months. Mesenteric venous Thrombosis is a relatively uncommon cause of Mesenteric ischemia that can be associated with severe morbidity and significant mortality. With noninvasive techniques, it is possible to establish a diagnosis in the majority of the cases. The importance of an early diagnosis and therapy - not only with anticoagulation, but also thrombolysis in selected cases - is shown with this case and review of the literature.

Uri Kopylov - One of the best experts on this subject based on the ideXlab platform.

  • Clinical and radiographic presentation of superior Mesenteric Vein Thrombosis in Crohn's disease: A single center experience
    Journal of Crohn's & colitis, 2011
    Co-Authors: Uri Kopylov, Marianne M. Amitai, Aharon Lubetsky, Rami Eliakim, Yehuda Chowers, Shomron Ben-horin
    Abstract:

    Abstract Background Mesenteric Vein Thrombosis (MVT) is a rare and frequently underdiagnosed complicationof Crohn's disease (CD). This study describes the clinical and radiological characteristics of CD /patients with superior Mesenteric Vein Thrombosis (MVT) diagnosed by CT/MRI. Patients and methods The database of Crohn's disease patients treated in Sheba Medical Center between 2005-2010 was searched for MVT diagnosis. Imaging studies of identified patients were retrieved and reviewed by an experienced abdominal radiologist. MVT was defined by superior Mesenteric Vein obliteration and/or thrombus in the vessel lumen on abdominal imaging. The clinical and radiologic data of these patients were collected from the medical records. Results MVT was demonstrated in 6/460 CD patients. Five patients had stricturing disease, and one patient had a combined fistulizing and stricturing disease phenotype. All patients had small bowel disease, but 3/6 also had colonic involvement. No patient had a prior thromboembolic history or demonstrable hypercoagulability. One patient had an acute SMV thrombus demonstrable on CT scanning, the remaining patients showed an obliteration of superior Mesenteric Vein. Two patients received anticoagulation upon diagnosis of Thrombosis. No subsequent thromboembolic events were recorded. Conclusions The incidence of Mesenteric Vein Thrombosis is likely to be underestimated in patients with Crohn’s disease. Both CT and MRI imaging demonstrate the extent of enteric disease and coincident SMV Thrombosis. In our cohort, Thrombosis was associated with stricturing disease of the small bowel. The clinical impact of SMV Thrombosis and whether anticoagulation is mandatory for all of these patients remains to be determined.

Rifat Latifi - One of the best experts on this subject based on the ideXlab platform.

  • clinical presentation and outcome of Mesenteric Vein Thrombosis a single center experience
    Angiology, 2015
    Co-Authors: Hassan Althani, Jamela Elmabrok, Ayman Elmenyar, Marym Alsulaiti, Abdel Hakem Tabeb, Khairi Hajaji, Hesham Elgohary, Mohammad Asim, Rifat Latifi
    Abstract:

    Mesenteric venous Thrombosis (MVT) is an uncommon event. We retrospectively analyzed data for patients who were admitted with MVT between June 2005 and May 2012 in Qatar. The study included 35 patients with a mean age of 45 ± 11 years. The risk of MVT was significantly high among males who smoked and females of Arab ethnicity. The main manifestations of MVT were abdominal distension and vomiting. The major etiological factors included deficiency in protein C and S, homocysteinemia, and prior abdominal surgery. Computed tomography (CT) findings were helpful in 80% of the patients. Bowel resection with primary anastomosis was performed in 25 (71%) patients. The overall mortality rate was 17%. High index of suspicion, detection of risk factors, CT imaging, and timely intervention are essential for better prognosis.