The Experts below are selected from a list of 309 Experts worldwide ranked by ideXlab platform

T. Pfammatter - One of the best experts on this subject based on the ideXlab platform.

Donghui Xu - One of the best experts on this subject based on the ideXlab platform.

Massimo Del Gaudio - One of the best experts on this subject based on the ideXlab platform.

A K Siriwardena - One of the best experts on this subject based on the ideXlab platform.

  • systematic review of outcome of synchronous portal superior Mesenteric Vein resection during pancreatectomy for cancer
    British Journal of Surgery, 2006
    Co-Authors: H P P Siriwardana, A K Siriwardena
    Abstract:

    BACKGROUND: Tumour clearance during pancreatectomy may be facilitated by resection of the portal-superior Mesenteric Vein, but this is associated with increased perioperative risk. There is no consensus about which patients benefit from portal-superior Mesenteric Vein resection. METHODS: A systematic appraisal was carried out of the literature on portal-superior Mesenteric Vein resection during pancreatectomy to identify recurrent themes to guide management. A computerized search of the Medline and Embase databases found 52 non-duplicated studies providing relevant data in 1646 patients. Pooled data were examined for information on outcome categories relating to operation, complications, histopathology and overall outcome. RESULTS: The median (range) number of patients with portal-superior Mesenteric Vein resection per cohort was 23 (4-172). Median operating time was 513 (168-1740) min and blood loss 1750 (300-26000) ml. Postoperative morbidity ranged from 9 to 78 per cent with a median per cohort of 42 per cent. There were 73 perioperative deaths (5.9 per cent of 1235 for whom mortality data were provided). Median survival was 13 months, and 1-, 3- and 5-year survival rates were 50, 16 and 7 per cent respectively. Specimen histopathology confirmed positive nodes in 67.4 per cent. CONCLUSIONS: This is the largest collective report to date on portal-superior Mesenteric Vein resection in pancreatectomy. The high rate of nodal metastases and low 5-year survival rates suggest that by the time of tumour involvement of the portal Vein cure is unlikely, even with radical resection.

Amir Dagan - One of the best experts on this subject based on the ideXlab platform.