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Masaki Mori - One of the best experts on this subject based on the ideXlab platform.
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Multiple liver metastases originating from synchronous double cancer of neuroendocrine tumor and rectal cancer: a case report
Surgical Case Reports, 2020Co-Authors: Sachie Omori, Noboru Harada, Takeo Toshima, Kazuki Takeishi, Shinji Itoh, Toru Ikegami, Tomoharu Yoshizumi, Masaki MoriAbstract:Background Neuroendocrine tumor (NET) is a relatively rare tumor and can develop in almost any organ, but primary mesenteric NETs are extremely rare. In addition, liver metastases from synchronous double cancer of neuroendocrine tumor graded as G1 and second primary malignancies (SPMs) have never been reported before. We herein report a case of multiple liver metastases from synchronous double cancer of NET (G1) at the ileal Mesentery and rectal cancer. Case presentation A 66-year-old man was identified as having tumors in the rectum and the ileal Mesentery by computed tomography (CT). He underwent laparoscopic low anterior resection for rectal cancer and biopsy of the ileal Mesentery Lymph Node and was diagnosed with rectal cancer as pT3 pN1 cM0 (stage IIIB) and NET (G1) of the ileal Mesentery. He received oxaliplatin and capecitabine (XELOX) for 3 months as adjuvant chemotherapy for rectal cancer. The NET (G1) of the ileal Mesentery was low grade and had not expanded at follow-up. A CT scan performed 4 years after the surgery indicated multiple liver metastases. All the metastases had the same findings on CT and magnetic resonance imaging (MRI). Thus, the patient underwent the first stage of modified associating liver partition and portal vein ligation for staged hepatectomy (modified ALPPS), comprising partial hepatectomies of segments 3 and 4, ligation of the right branch of portal vein, and hepatic partition on the demarcation line, followed by the second stage of modified ALPPS (right lobectomy). Histopathological findings revealed that the 14 nodules were metastatic liver tumors of rectal cancer and the 2 nodules were liver metastases of the NET (G1). Conclusions Our findings suggest that synchronous double cancer of NET and gastrointestinal cancer may be indistinguishable in preoperative images. However, curative resection, precise pathological diagnosis, and adequately adjusted treatment may result in a better prognosis.
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Multiple liver metastases originating from synchronous double cancer of neuroendocrine tumor and rectal cancer: a case report.
Surgical case reports, 2020Co-Authors: Sachie Omori, Noboru Harada, Takeo Toshima, Kazuki Takeishi, Shinji Itoh, Toru Ikegami, Tomoharu Yoshizumi, Masaki MoriAbstract:Neuroendocrine tumor (NET) is a relatively rare tumor and can develop in almost any organ, but primary mesenteric NETs are extremely rare. In addition, liver metastases from synchronous double cancer of neuroendocrine tumor graded as G1 and second primary malignancies (SPMs) have never been reported before. We herein report a case of multiple liver metastases from synchronous double cancer of NET (G1) at the ileal Mesentery and rectal cancer. A 66-year-old man was identified as having tumors in the rectum and the ileal Mesentery by computed tomography (CT). He underwent laparoscopic low anterior resection for rectal cancer and biopsy of the ileal Mesentery Lymph Node and was diagnosed with rectal cancer as pT3 pN1 cM0 (stage IIIB) and NET (G1) of the ileal Mesentery. He received oxaliplatin and capecitabine (XELOX) for 3 months as adjuvant chemotherapy for rectal cancer. The NET (G1) of the ileal Mesentery was low grade and had not expanded at follow-up. A CT scan performed 4 years after the surgery indicated multiple liver metastases. All the metastases had the same findings on CT and magnetic resonance imaging (MRI). Thus, the patient underwent the first stage of modified associating liver partition and portal vein ligation for staged hepatectomy (modified ALPPS), comprising partial hepatectomies of segments 3 and 4, ligation of the right branch of portal vein, and hepatic partition on the demarcation line, followed by the second stage of modified ALPPS (right lobectomy). Histopathological findings revealed that the 14 nodules were metastatic liver tumors of rectal cancer and the 2 nodules were liver metastases of the NET (G1). Our findings suggest that synchronous double cancer of NET and gastrointestinal cancer may be indistinguishable in preoperative images. However, curative resection, precise pathological diagnosis, and adequately adjusted treatment may result in a better prognosis.
Sachie Omori - One of the best experts on this subject based on the ideXlab platform.
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Multiple liver metastases originating from synchronous double cancer of neuroendocrine tumor and rectal cancer: a case report
Surgical Case Reports, 2020Co-Authors: Sachie Omori, Noboru Harada, Takeo Toshima, Kazuki Takeishi, Shinji Itoh, Toru Ikegami, Tomoharu Yoshizumi, Masaki MoriAbstract:Background Neuroendocrine tumor (NET) is a relatively rare tumor and can develop in almost any organ, but primary mesenteric NETs are extremely rare. In addition, liver metastases from synchronous double cancer of neuroendocrine tumor graded as G1 and second primary malignancies (SPMs) have never been reported before. We herein report a case of multiple liver metastases from synchronous double cancer of NET (G1) at the ileal Mesentery and rectal cancer. Case presentation A 66-year-old man was identified as having tumors in the rectum and the ileal Mesentery by computed tomography (CT). He underwent laparoscopic low anterior resection for rectal cancer and biopsy of the ileal Mesentery Lymph Node and was diagnosed with rectal cancer as pT3 pN1 cM0 (stage IIIB) and NET (G1) of the ileal Mesentery. He received oxaliplatin and capecitabine (XELOX) for 3 months as adjuvant chemotherapy for rectal cancer. The NET (G1) of the ileal Mesentery was low grade and had not expanded at follow-up. A CT scan performed 4 years after the surgery indicated multiple liver metastases. All the metastases had the same findings on CT and magnetic resonance imaging (MRI). Thus, the patient underwent the first stage of modified associating liver partition and portal vein ligation for staged hepatectomy (modified ALPPS), comprising partial hepatectomies of segments 3 and 4, ligation of the right branch of portal vein, and hepatic partition on the demarcation line, followed by the second stage of modified ALPPS (right lobectomy). Histopathological findings revealed that the 14 nodules were metastatic liver tumors of rectal cancer and the 2 nodules were liver metastases of the NET (G1). Conclusions Our findings suggest that synchronous double cancer of NET and gastrointestinal cancer may be indistinguishable in preoperative images. However, curative resection, precise pathological diagnosis, and adequately adjusted treatment may result in a better prognosis.
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Multiple liver metastases originating from synchronous double cancer of neuroendocrine tumor and rectal cancer: a case report.
Surgical case reports, 2020Co-Authors: Sachie Omori, Noboru Harada, Takeo Toshima, Kazuki Takeishi, Shinji Itoh, Toru Ikegami, Tomoharu Yoshizumi, Masaki MoriAbstract:Neuroendocrine tumor (NET) is a relatively rare tumor and can develop in almost any organ, but primary mesenteric NETs are extremely rare. In addition, liver metastases from synchronous double cancer of neuroendocrine tumor graded as G1 and second primary malignancies (SPMs) have never been reported before. We herein report a case of multiple liver metastases from synchronous double cancer of NET (G1) at the ileal Mesentery and rectal cancer. A 66-year-old man was identified as having tumors in the rectum and the ileal Mesentery by computed tomography (CT). He underwent laparoscopic low anterior resection for rectal cancer and biopsy of the ileal Mesentery Lymph Node and was diagnosed with rectal cancer as pT3 pN1 cM0 (stage IIIB) and NET (G1) of the ileal Mesentery. He received oxaliplatin and capecitabine (XELOX) for 3 months as adjuvant chemotherapy for rectal cancer. The NET (G1) of the ileal Mesentery was low grade and had not expanded at follow-up. A CT scan performed 4 years after the surgery indicated multiple liver metastases. All the metastases had the same findings on CT and magnetic resonance imaging (MRI). Thus, the patient underwent the first stage of modified associating liver partition and portal vein ligation for staged hepatectomy (modified ALPPS), comprising partial hepatectomies of segments 3 and 4, ligation of the right branch of portal vein, and hepatic partition on the demarcation line, followed by the second stage of modified ALPPS (right lobectomy). Histopathological findings revealed that the 14 nodules were metastatic liver tumors of rectal cancer and the 2 nodules were liver metastases of the NET (G1). Our findings suggest that synchronous double cancer of NET and gastrointestinal cancer may be indistinguishable in preoperative images. However, curative resection, precise pathological diagnosis, and adequately adjusted treatment may result in a better prognosis.
Zhu Yang-hua - One of the best experts on this subject based on the ideXlab platform.
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Application of Ultrasound in Diagnosis of Children with Mesenteric Lymphnoditis
Journal of Kunming Medical University, 2009Co-Authors: Zhu Yang-huaAbstract:Objective To provide diagnostic basis for children with mesenteric Lymphnoditis.Method Children with acute upper respiratory tract infection,fever and the abdominal pain received conventional abdomen supersonic and the high frequency supersonic(CDF)I inspection to find whether there was tumescent mesenteric Lymph Nodes.Results Twenty six showed simple Mesentery Lymph Node tumescence,3 cases were simultaneously accompanied with acute appendicitis.Supersonic examination showed tumescent Lymph Node on right side of navel and right under abdomen or right abdomen,CDFI:In the Lymph Node sees sparse or the rich colored blood stream,the maximum blood stream speed was(20±5)cm/s,RI was about 0.5.Conclusion The high frequency supersonic examination of mesenteric Lymphnoditis has certain specificity,can simultaneously discover pathological changes and acute appendicitis,and has the important clinical value is early diagnosis and the distinction diagnosis of young children with acute abdokminal pains.
Yu Ming - One of the best experts on this subject based on the ideXlab platform.
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Apoptosis of immune organ during gut ischemia/reperfusion injury:a molecular study
Chinese Journal of Pediatric Surgery, 2002Co-Authors: Yu MingAbstract:Objective To examine the molecular changes in immune organs of immature rats during gut inschemia/reperfusion injury.Methods Thirty two male immature Wistar rats were divided randomly into four groups: 1) Physiological control group,2) Anesthesia control group,3) Sham control group and 4) Experimental group.Apoptosis in immune organs was assessed by electromicroscopy and TUNEL technique.The expression of Fas/Fas L mRNA in immune organ were assessed by in situ hybridization.Results Spleen apoptosis was located mainly in splenic sinus.Mesentery Lymph Node apoptosis was mainly seen in medullary sinus.There was significant increase of apoptosis in group III and IV.In thymus expression of Fas/Fas L mRNA was hardly detected.In spleen,the expression of Fas mRNA was higher than that of Fas L mRNA.In Mesentery Lymph,the expression of Fas L mRNA was higher than that of Fas mRNA.Conclusions 1) Fas expression is higher than that of Fas L in spleen.This implies increased Fas expression induces apoptosis in spleen.On the other hand,high Fas L expression in Mesentery Lymph Node implies its role in apoptosis induction.2) In the earlier period of gut I/R,Fas/Fas L induced apoptosis in immune organs may affect the host immune status.
Shinji Itoh - One of the best experts on this subject based on the ideXlab platform.
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Multiple liver metastases originating from synchronous double cancer of neuroendocrine tumor and rectal cancer: a case report
Surgical Case Reports, 2020Co-Authors: Sachie Omori, Noboru Harada, Takeo Toshima, Kazuki Takeishi, Shinji Itoh, Toru Ikegami, Tomoharu Yoshizumi, Masaki MoriAbstract:Background Neuroendocrine tumor (NET) is a relatively rare tumor and can develop in almost any organ, but primary mesenteric NETs are extremely rare. In addition, liver metastases from synchronous double cancer of neuroendocrine tumor graded as G1 and second primary malignancies (SPMs) have never been reported before. We herein report a case of multiple liver metastases from synchronous double cancer of NET (G1) at the ileal Mesentery and rectal cancer. Case presentation A 66-year-old man was identified as having tumors in the rectum and the ileal Mesentery by computed tomography (CT). He underwent laparoscopic low anterior resection for rectal cancer and biopsy of the ileal Mesentery Lymph Node and was diagnosed with rectal cancer as pT3 pN1 cM0 (stage IIIB) and NET (G1) of the ileal Mesentery. He received oxaliplatin and capecitabine (XELOX) for 3 months as adjuvant chemotherapy for rectal cancer. The NET (G1) of the ileal Mesentery was low grade and had not expanded at follow-up. A CT scan performed 4 years after the surgery indicated multiple liver metastases. All the metastases had the same findings on CT and magnetic resonance imaging (MRI). Thus, the patient underwent the first stage of modified associating liver partition and portal vein ligation for staged hepatectomy (modified ALPPS), comprising partial hepatectomies of segments 3 and 4, ligation of the right branch of portal vein, and hepatic partition on the demarcation line, followed by the second stage of modified ALPPS (right lobectomy). Histopathological findings revealed that the 14 nodules were metastatic liver tumors of rectal cancer and the 2 nodules were liver metastases of the NET (G1). Conclusions Our findings suggest that synchronous double cancer of NET and gastrointestinal cancer may be indistinguishable in preoperative images. However, curative resection, precise pathological diagnosis, and adequately adjusted treatment may result in a better prognosis.
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Multiple liver metastases originating from synchronous double cancer of neuroendocrine tumor and rectal cancer: a case report.
Surgical case reports, 2020Co-Authors: Sachie Omori, Noboru Harada, Takeo Toshima, Kazuki Takeishi, Shinji Itoh, Toru Ikegami, Tomoharu Yoshizumi, Masaki MoriAbstract:Neuroendocrine tumor (NET) is a relatively rare tumor and can develop in almost any organ, but primary mesenteric NETs are extremely rare. In addition, liver metastases from synchronous double cancer of neuroendocrine tumor graded as G1 and second primary malignancies (SPMs) have never been reported before. We herein report a case of multiple liver metastases from synchronous double cancer of NET (G1) at the ileal Mesentery and rectal cancer. A 66-year-old man was identified as having tumors in the rectum and the ileal Mesentery by computed tomography (CT). He underwent laparoscopic low anterior resection for rectal cancer and biopsy of the ileal Mesentery Lymph Node and was diagnosed with rectal cancer as pT3 pN1 cM0 (stage IIIB) and NET (G1) of the ileal Mesentery. He received oxaliplatin and capecitabine (XELOX) for 3 months as adjuvant chemotherapy for rectal cancer. The NET (G1) of the ileal Mesentery was low grade and had not expanded at follow-up. A CT scan performed 4 years after the surgery indicated multiple liver metastases. All the metastases had the same findings on CT and magnetic resonance imaging (MRI). Thus, the patient underwent the first stage of modified associating liver partition and portal vein ligation for staged hepatectomy (modified ALPPS), comprising partial hepatectomies of segments 3 and 4, ligation of the right branch of portal vein, and hepatic partition on the demarcation line, followed by the second stage of modified ALPPS (right lobectomy). Histopathological findings revealed that the 14 nodules were metastatic liver tumors of rectal cancer and the 2 nodules were liver metastases of the NET (G1). Our findings suggest that synchronous double cancer of NET and gastrointestinal cancer may be indistinguishable in preoperative images. However, curative resection, precise pathological diagnosis, and adequately adjusted treatment may result in a better prognosis.