The Experts below are selected from a list of 4266 Experts worldwide ranked by ideXlab platform
P F Misco - One of the best experts on this subject based on the ideXlab platform.
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oxidation of alcohols by Methyl Sulfide n chlorosuccinimide triethylamine 4 tert butylcyclohexanone
Organic Syntheses, 2003Co-Authors: E J Corey, C U Kim, P F MiscoAbstract:Oxidation of alcohols by Methyl Sulfide- N-chlorosuccinimide- triethylamine: 4-tert-butylcyclohexanone catalyst: 8.0 g. (0.060 mole) of N-chlorosuccinimide product: 4-tert-butylcyclohexanone byproduct: 4-tert-butylcyclohexylMethyl MethylthioMethyl ether product: C6H5CHO Keywords: oxidation, CHOH CO; N-chlorosuccinimide; diMethyl sulfoxide-Methyl Sulfide reagent
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Organic Syntheses - Oxidation of Alcohols by Methyl Sulfide‐ N‐Chlorosuccinimide‐ Triethylamine: 4‐tert‐Butylcyclohexanone
Organic Syntheses, 2003Co-Authors: E J Corey, C U Kim, P F MiscoAbstract:Oxidation of alcohols by Methyl Sulfide- N-chlorosuccinimide- triethylamine: 4-tert-butylcyclohexanone catalyst: 8.0 g. (0.060 mole) of N-chlorosuccinimide product: 4-tert-butylcyclohexanone byproduct: 4-tert-butylcyclohexylMethyl MethylthioMethyl ether product: C6H5CHO Keywords: oxidation, CHOH CO; N-chlorosuccinimide; diMethyl sulfoxide-Methyl Sulfide reagent
E J Corey - One of the best experts on this subject based on the ideXlab platform.
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oxidation of alcohols by Methyl Sulfide n chlorosuccinimide triethylamine 4 tert butylcyclohexanone
Organic Syntheses, 2003Co-Authors: E J Corey, C U Kim, P F MiscoAbstract:Oxidation of alcohols by Methyl Sulfide- N-chlorosuccinimide- triethylamine: 4-tert-butylcyclohexanone catalyst: 8.0 g. (0.060 mole) of N-chlorosuccinimide product: 4-tert-butylcyclohexanone byproduct: 4-tert-butylcyclohexylMethyl MethylthioMethyl ether product: C6H5CHO Keywords: oxidation, CHOH CO; N-chlorosuccinimide; diMethyl sulfoxide-Methyl Sulfide reagent
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Organic Syntheses - Oxidation of Alcohols by Methyl Sulfide‐ N‐Chlorosuccinimide‐ Triethylamine: 4‐tert‐Butylcyclohexanone
Organic Syntheses, 2003Co-Authors: E J Corey, C U Kim, P F MiscoAbstract:Oxidation of alcohols by Methyl Sulfide- N-chlorosuccinimide- triethylamine: 4-tert-butylcyclohexanone catalyst: 8.0 g. (0.060 mole) of N-chlorosuccinimide product: 4-tert-butylcyclohexanone byproduct: 4-tert-butylcyclohexylMethyl MethylthioMethyl ether product: C6H5CHO Keywords: oxidation, CHOH CO; N-chlorosuccinimide; diMethyl sulfoxide-Methyl Sulfide reagent
Noboru Morita - One of the best experts on this subject based on the ideXlab platform.
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heteroarylation of 1 azulenyl Methyl Sulfide two step synthetic strategy for 1 Methylthio 3 heteroaryl azulenes using the triflate of n containing heterocycles
European Journal of Organic Chemistry, 2008Co-Authors: Junya Higashi, Taku Shoji, Shunji Ito, Kozo Toyota, Masafumi Yasunami, Noboru MoritaAbstract:1-Azulenyl Methyl Sulfide reacts with highly electrophilic trifluoromethanesulfonates of N-heterocycles, that is, pyridine, isoquinoline, 1,10-phenanthroline, benzothiazole, quinoline, and acridine, to give 1-Methylthio-3-(dihydroheteroaryl)azulenes in good yields. In the case of the reaction with the trifluoromethanesulfonate of pyridine, 1-Methylthio-3-pyridylazulene was obtained directly under certain reaction conditions. Treatment of the 1-Methylthio-3-(dihydroheteroaryl)azulenes with KOH or tBuOK afforded the corresponding 1-Methylthio-3-(heteroaryl)azulenes in good yields. The redox behavior of these 1-Methylthio-3-(heteroaryl)azulenes was examined by cyclic voltammetry and differential pulse voltammetry.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
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Heteroarylation of 1‐Azulenyl Methyl Sulfide: Two‐Step Synthetic Strategy for 1‐Methylthio‐3‐(heteroaryl)azulenes Using the Triflate of N‐Containing Heterocycles
European Journal of Organic Chemistry, 2008Co-Authors: Junya Higashi, Taku Shoji, Shunji Ito, Kozo Toyota, Masafumi Yasunami, Noboru MoritaAbstract:1-Azulenyl Methyl Sulfide reacts with highly electrophilic trifluoromethanesulfonates of N-heterocycles, that is, pyridine, isoquinoline, 1,10-phenanthroline, benzothiazole, quinoline, and acridine, to give 1-Methylthio-3-(dihydroheteroaryl)azulenes in good yields. In the case of the reaction with the trifluoromethanesulfonate of pyridine, 1-Methylthio-3-pyridylazulene was obtained directly under certain reaction conditions. Treatment of the 1-Methylthio-3-(dihydroheteroaryl)azulenes with KOH or tBuOK afforded the corresponding 1-Methylthio-3-(heteroaryl)azulenes in good yields. The redox behavior of these 1-Methylthio-3-(heteroaryl)azulenes was examined by cyclic voltammetry and differential pulse voltammetry.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
C U Kim - One of the best experts on this subject based on the ideXlab platform.
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oxidation of alcohols by Methyl Sulfide n chlorosuccinimide triethylamine 4 tert butylcyclohexanone
Organic Syntheses, 2003Co-Authors: E J Corey, C U Kim, P F MiscoAbstract:Oxidation of alcohols by Methyl Sulfide- N-chlorosuccinimide- triethylamine: 4-tert-butylcyclohexanone catalyst: 8.0 g. (0.060 mole) of N-chlorosuccinimide product: 4-tert-butylcyclohexanone byproduct: 4-tert-butylcyclohexylMethyl MethylthioMethyl ether product: C6H5CHO Keywords: oxidation, CHOH CO; N-chlorosuccinimide; diMethyl sulfoxide-Methyl Sulfide reagent
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Organic Syntheses - Oxidation of Alcohols by Methyl Sulfide‐ N‐Chlorosuccinimide‐ Triethylamine: 4‐tert‐Butylcyclohexanone
Organic Syntheses, 2003Co-Authors: E J Corey, C U Kim, P F MiscoAbstract:Oxidation of alcohols by Methyl Sulfide- N-chlorosuccinimide- triethylamine: 4-tert-butylcyclohexanone catalyst: 8.0 g. (0.060 mole) of N-chlorosuccinimide product: 4-tert-butylcyclohexanone byproduct: 4-tert-butylcyclohexylMethyl MethylthioMethyl ether product: C6H5CHO Keywords: oxidation, CHOH CO; N-chlorosuccinimide; diMethyl sulfoxide-Methyl Sulfide reagent
Michael C Willis - One of the best experts on this subject based on the ideXlab platform.
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carbon carbon bond construction using boronic acids and aryl Methyl Sulfides orthogonal reactivity in suzuki type couplings
Chemical Science, 2013Co-Authors: Joel F Hooper, Andrew S Weller, Rowan D Young, Indrek Pernik, Michael C WillisAbstract:The Rh(I)-catalysed coupling of aryl and alkenyl boronic acids with simple aryl and alkenyl Methyl Sulfides is reported. The process employs bench-stable Rh(I) precatalysts incorporating small bite-angle chelating phosphine ligands (R2PCH2PR2, R = iPr, Cy), shows good functional group tolerance, and proceeds under mild reaction conditions. Importantly, aryl bromide activating groups are inert to the reaction conditions, allowing selective reaction at either a Methyl Sulfide or bromide activating group, depending on catalyst (metal) choice. The scope of the coupling reactions, their combination with Rh-catalysed hydroacylation reactions in cascade processes, together with preliminary mechanistic studies, are all documented.
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Carbon–carbon bond construction using boronic acids and aryl Methyl Sulfides: orthogonal reactivity in Suzuki-type couplings
Chemical Science, 2013Co-Authors: Joel F Hooper, Andrew S Weller, Rowan D Young, Indrek Pernik, Michael C WillisAbstract:The Rh(I)-catalysed coupling of aryl and alkenyl boronic acids with simple aryl and alkenyl Methyl Sulfides is reported. The process employs bench-stable Rh(I) precatalysts incorporating small bite-angle chelating phosphine ligands (R2PCH2PR2, R = iPr, Cy), shows good functional group tolerance, and proceeds under mild reaction conditions. Importantly, aryl bromide activating groups are inert to the reaction conditions, allowing selective reaction at either a Methyl Sulfide or bromide activating group, depending on catalyst (metal) choice. The scope of the coupling reactions, their combination with Rh-catalysed hydroacylation reactions in cascade processes, together with preliminary mechanistic studies, are all documented.
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aryl Methyl Sulfides as substrates for rhodium catalyzed alkyne carbothiolation arene functionalization with activating group recycling
Journal of the American Chemical Society, 2012Co-Authors: Joel F Hooper, Adrian B Chaplin, Carlos Gonzalezrodriguez, Andrew S Weller, Amber L. Thompson, Michael C WillisAbstract:A Rh(I)-catalyzed method for the efficient functionalization of arenes is reported. Aryl Methyl Sulfides are combined with terminal alkynes to deliver products of carbothiolation. The overall process results in reincorporation of the original arene functional group, a Methyl Sulfide, into the products as an alkenyl Sulfide. The carbothiolation process can be combined with an initial Rh(I)-catalyzed alkene or alkyne hydroacylation reaction in three-component cascade sequences. The utility of the alkenyl Sulfide products is also demonstrated in simple carbo- and heterocycle-forming processes. We also provide mechanistic evidence for the course of this new process.