The Experts below are selected from a list of 6 Experts worldwide ranked by ideXlab platform

James B. Gloer - One of the best experts on this subject based on the ideXlab platform.

  • Bioactive Rearrangement Products from Aqueous Photolysis of Pharmaceutical Steroids.
    Organic letters, 2019
    Co-Authors: Nicholas C. Pflug, Christopher J. Knutson, Dale C. Swenson, Kristine H. Wammer, David M. Cwiertny, Dalma Martinović-weigelt, James B. Gloer
    Abstract:

    In an ongoing effort to study the environmental fate of endocrine-active steroid hormones, we report the formation of phenolic rearrangement products (3 and 4) with a novel 6,5,8,5-ring system following aqueous photolysis of dienogest (1) and Methyldienolone (2). The structures were established by analysis of 2D NMR and HRMS data, and that of 3 was confirmed by X-ray diffraction analysis. These photoproducts exhibit progestogenic and androgenic activity, albeit with less potency than their parent compounds.

  • Bioactive Rearrangement Products from Aqueous Photolysis of Pharmaceutical Steroids
    2019
    Co-Authors: Nicholas C. Pflug, Christopher J. Knutson, Dalma Martinović-weigelt, Dale C. Swenson, Kristine H. Wammer, David M. Cwiertny, James B. Gloer
    Abstract:

    In an ongoing effort to study the environmental fate of endocrine-active steroid hormones, we report the formation of phenolic rearrangement products (3 and 4) with a novel 6,5,8,5-ring system following aqueous photolysis of dienogest (1) and Methyldienolone (2). The structures were established by analysis of 2D NMR and HRMS data, and that of 3 was confirmed by X-ray diffraction analysis. These photoproducts exhibit progestogenic and androgenic activity, albeit with less potency than their parent compounds

Nicholas C. Pflug - One of the best experts on this subject based on the ideXlab platform.

  • Bioactive Rearrangement Products from Aqueous Photolysis of Pharmaceutical Steroids.
    Organic letters, 2019
    Co-Authors: Nicholas C. Pflug, Christopher J. Knutson, Dale C. Swenson, Kristine H. Wammer, David M. Cwiertny, Dalma Martinović-weigelt, James B. Gloer
    Abstract:

    In an ongoing effort to study the environmental fate of endocrine-active steroid hormones, we report the formation of phenolic rearrangement products (3 and 4) with a novel 6,5,8,5-ring system following aqueous photolysis of dienogest (1) and Methyldienolone (2). The structures were established by analysis of 2D NMR and HRMS data, and that of 3 was confirmed by X-ray diffraction analysis. These photoproducts exhibit progestogenic and androgenic activity, albeit with less potency than their parent compounds.

Christopher J. Knutson - One of the best experts on this subject based on the ideXlab platform.

  • Bioactive Rearrangement Products from Aqueous Photolysis of Pharmaceutical Steroids.
    Organic letters, 2019
    Co-Authors: Nicholas C. Pflug, Christopher J. Knutson, Dale C. Swenson, Kristine H. Wammer, David M. Cwiertny, Dalma Martinović-weigelt, James B. Gloer
    Abstract:

    In an ongoing effort to study the environmental fate of endocrine-active steroid hormones, we report the formation of phenolic rearrangement products (3 and 4) with a novel 6,5,8,5-ring system following aqueous photolysis of dienogest (1) and Methyldienolone (2). The structures were established by analysis of 2D NMR and HRMS data, and that of 3 was confirmed by X-ray diffraction analysis. These photoproducts exhibit progestogenic and androgenic activity, albeit with less potency than their parent compounds.

  • Bioactive Rearrangement Products from Aqueous Photolysis of Pharmaceutical Steroids
    2019
    Co-Authors: Nicholas C. Pflug, Christopher J. Knutson, Dalma Martinović-weigelt, Dale C. Swenson, Kristine H. Wammer, David M. Cwiertny, James B. Gloer
    Abstract:

    In an ongoing effort to study the environmental fate of endocrine-active steroid hormones, we report the formation of phenolic rearrangement products (3 and 4) with a novel 6,5,8,5-ring system following aqueous photolysis of dienogest (1) and Methyldienolone (2). The structures were established by analysis of 2D NMR and HRMS data, and that of 3 was confirmed by X-ray diffraction analysis. These photoproducts exhibit progestogenic and androgenic activity, albeit with less potency than their parent compounds

Dale C. Swenson - One of the best experts on this subject based on the ideXlab platform.

  • Bioactive Rearrangement Products from Aqueous Photolysis of Pharmaceutical Steroids.
    Organic letters, 2019
    Co-Authors: Nicholas C. Pflug, Christopher J. Knutson, Dale C. Swenson, Kristine H. Wammer, David M. Cwiertny, Dalma Martinović-weigelt, James B. Gloer
    Abstract:

    In an ongoing effort to study the environmental fate of endocrine-active steroid hormones, we report the formation of phenolic rearrangement products (3 and 4) with a novel 6,5,8,5-ring system following aqueous photolysis of dienogest (1) and Methyldienolone (2). The structures were established by analysis of 2D NMR and HRMS data, and that of 3 was confirmed by X-ray diffraction analysis. These photoproducts exhibit progestogenic and androgenic activity, albeit with less potency than their parent compounds.

  • Bioactive Rearrangement Products from Aqueous Photolysis of Pharmaceutical Steroids
    2019
    Co-Authors: Nicholas C. Pflug, Christopher J. Knutson, Dalma Martinović-weigelt, Dale C. Swenson, Kristine H. Wammer, David M. Cwiertny, James B. Gloer
    Abstract:

    In an ongoing effort to study the environmental fate of endocrine-active steroid hormones, we report the formation of phenolic rearrangement products (3 and 4) with a novel 6,5,8,5-ring system following aqueous photolysis of dienogest (1) and Methyldienolone (2). The structures were established by analysis of 2D NMR and HRMS data, and that of 3 was confirmed by X-ray diffraction analysis. These photoproducts exhibit progestogenic and androgenic activity, albeit with less potency than their parent compounds

Kristine H. Wammer - One of the best experts on this subject based on the ideXlab platform.

  • Bioactive Rearrangement Products from Aqueous Photolysis of Pharmaceutical Steroids.
    Organic letters, 2019
    Co-Authors: Nicholas C. Pflug, Christopher J. Knutson, Dale C. Swenson, Kristine H. Wammer, David M. Cwiertny, Dalma Martinović-weigelt, James B. Gloer
    Abstract:

    In an ongoing effort to study the environmental fate of endocrine-active steroid hormones, we report the formation of phenolic rearrangement products (3 and 4) with a novel 6,5,8,5-ring system following aqueous photolysis of dienogest (1) and Methyldienolone (2). The structures were established by analysis of 2D NMR and HRMS data, and that of 3 was confirmed by X-ray diffraction analysis. These photoproducts exhibit progestogenic and androgenic activity, albeit with less potency than their parent compounds.

  • Bioactive Rearrangement Products from Aqueous Photolysis of Pharmaceutical Steroids
    2019
    Co-Authors: Nicholas C. Pflug, Christopher J. Knutson, Dalma Martinović-weigelt, Dale C. Swenson, Kristine H. Wammer, David M. Cwiertny, James B. Gloer
    Abstract:

    In an ongoing effort to study the environmental fate of endocrine-active steroid hormones, we report the formation of phenolic rearrangement products (3 and 4) with a novel 6,5,8,5-ring system following aqueous photolysis of dienogest (1) and Methyldienolone (2). The structures were established by analysis of 2D NMR and HRMS data, and that of 3 was confirmed by X-ray diffraction analysis. These photoproducts exhibit progestogenic and androgenic activity, albeit with less potency than their parent compounds