The Experts below are selected from a list of 27 Experts worldwide ranked by ideXlab platform
M Rinji D Murakami - One of the best experts on this subject based on the ideXlab platform.
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myocardial ischemia due to vasospasm of small coronary arteries detected by Methylergometrine Maleate stress myocardial scintigraphy
Clinical Cardiology, 1999Co-Authors: M Toshio D Shimada, M Yutaka D Ishibashi, M Yo D Murakami, M Kazuya D Sano, M Hironori D Tsukihashi, M Seiji D Okada, M Koichi D Kawakami, M Rinji D MurakamiAbstract:Background: Recently, several case reports have implicated vasospasm of small coronary arteries in vasospastic angina pectoris. Vasospasm of small coronary arteries was also considered from angiographic findings in patients with atypical chest pain. In Syrian hamster, vasospasm in small coronary arteries was considered to be the cause of dilated cardiomyopathy. Hypothesis: This study was undertaken to determine whether vasospasm in small coronary arteries can be induced by Methylergometrine Maleate stress thallium-201 (201T1) myocardial scintigraphy. Methods: Twenty-five patients with chest pain, all of whom had intact coronary arteries, were studied. After intracoronary Methylergometrine Maleate injection, coronary arteriograms also looked normal in all cases. Thallium-201 myocardial scintigraphy was carried out immediately after intracoronary Methylergometrine Maleate injection in four patients with chest pain. In the remaining 21 patients with chest pain, Methylergometrine Maleate was given intravenously within up to 2 weeks before 201T1 myocardial scintigraphy. Results: In the intracoronary injection study, one patient had chest discomfort after Methylergometrine Maleate injection, and ST-segment elevation was observed on electrocardiogram (ECG). Of the 21 patients with chest pain, 11 patients felt angina-like chest pain after intravenous injection of Methylergometrine Maleate, but their ECGs showed no ischemic changes. Stress 201T1 myocardial scintigrams showed Methylergometrine Maleate-induced perfusion defects with complete redistribution in 3 of 4 patients in the intracoronary injection study and in 12 of 21 patients in the intravenous injection study. These findings suggest that vasospasm in small coronary arteries caused myocardial ischemia in 15 of 25 patients (60%) with chest pain. Conclusion: Vasospasm in small coronary arteries may be involved in the myocardial ischemia of some patients with chest pain who do not show any large coronary artery vasospasm.
M Toshio D Shimada - One of the best experts on this subject based on the ideXlab platform.
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myocardial ischemia due to vasospasm of small coronary arteries detected by Methylergometrine Maleate stress myocardial scintigraphy
Clinical Cardiology, 1999Co-Authors: M Toshio D Shimada, M Yutaka D Ishibashi, M Yo D Murakami, M Kazuya D Sano, M Hironori D Tsukihashi, M Seiji D Okada, M Koichi D Kawakami, M Rinji D MurakamiAbstract:Background: Recently, several case reports have implicated vasospasm of small coronary arteries in vasospastic angina pectoris. Vasospasm of small coronary arteries was also considered from angiographic findings in patients with atypical chest pain. In Syrian hamster, vasospasm in small coronary arteries was considered to be the cause of dilated cardiomyopathy. Hypothesis: This study was undertaken to determine whether vasospasm in small coronary arteries can be induced by Methylergometrine Maleate stress thallium-201 (201T1) myocardial scintigraphy. Methods: Twenty-five patients with chest pain, all of whom had intact coronary arteries, were studied. After intracoronary Methylergometrine Maleate injection, coronary arteriograms also looked normal in all cases. Thallium-201 myocardial scintigraphy was carried out immediately after intracoronary Methylergometrine Maleate injection in four patients with chest pain. In the remaining 21 patients with chest pain, Methylergometrine Maleate was given intravenously within up to 2 weeks before 201T1 myocardial scintigraphy. Results: In the intracoronary injection study, one patient had chest discomfort after Methylergometrine Maleate injection, and ST-segment elevation was observed on electrocardiogram (ECG). Of the 21 patients with chest pain, 11 patients felt angina-like chest pain after intravenous injection of Methylergometrine Maleate, but their ECGs showed no ischemic changes. Stress 201T1 myocardial scintigrams showed Methylergometrine Maleate-induced perfusion defects with complete redistribution in 3 of 4 patients in the intracoronary injection study and in 12 of 21 patients in the intravenous injection study. These findings suggest that vasospasm in small coronary arteries caused myocardial ischemia in 15 of 25 patients (60%) with chest pain. Conclusion: Vasospasm in small coronary arteries may be involved in the myocardial ischemia of some patients with chest pain who do not show any large coronary artery vasospasm.
Ashwini K Srivastava - One of the best experts on this subject based on the ideXlab platform.
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highly sensitive and selective determination of Methylergometrine Maleate using carbon nanofibers silver nanoparticles composite modified carbon paste electrode
Materials Science and Engineering: C, 2016Co-Authors: Pramod K Kalambate, Chaitali R Rawool, Shashi P Karna, Ashwini K SrivastavaAbstract:A highly sensitive and selective voltammetric method for determination of Methylergometrine Maleate (MM) in pharmaceutical formulations, urine and blood serum samples has been developed based on enhanced electrochemical response of MM at carbon nanofibers and silver nanoparticles modified carbon paste electrode (CNF-AgNP-CPE). The electrode material was characterized by various techniques viz., X-ray diffraction, scanning electron microscopy and energy dispersive X-ray spectroscopy. The electrocatalytic response of MM at CNF-AgNP-CPE was studied by cyclic voltammetry (CV), differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS). Under optimized conditions, the proposed sensor exhibits excellent electrochemical response towards MM. The DPV study shows greatly enhanced electrochemical signal for MM at CNF-AgNP-CPE lending high sensitivity to the proposed sensor for MM detection. The peak (Ip) current for MM is found to be rectilinear in the range 4.0×10(-8)-2.0×10(-5)M with a detection limit of 7.1×10(-9)M using DPV. The feasibility of the proposed sensor in analytical applications was investigated by conducting experiments on commercial pharmaceutical formulations, human urine and blood serum samples, which yielded satisfactory recoveries of MM. The proposed electrochemical sensor offers high sensitivity, selectivity, reproducibility and practical utility. We recommend it as an authentic and productive electrochemical sensor for successful determination of MM.
M Yutaka D Ishibashi - One of the best experts on this subject based on the ideXlab platform.
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myocardial ischemia due to vasospasm of small coronary arteries detected by Methylergometrine Maleate stress myocardial scintigraphy
Clinical Cardiology, 1999Co-Authors: M Toshio D Shimada, M Yutaka D Ishibashi, M Yo D Murakami, M Kazuya D Sano, M Hironori D Tsukihashi, M Seiji D Okada, M Koichi D Kawakami, M Rinji D MurakamiAbstract:Background: Recently, several case reports have implicated vasospasm of small coronary arteries in vasospastic angina pectoris. Vasospasm of small coronary arteries was also considered from angiographic findings in patients with atypical chest pain. In Syrian hamster, vasospasm in small coronary arteries was considered to be the cause of dilated cardiomyopathy. Hypothesis: This study was undertaken to determine whether vasospasm in small coronary arteries can be induced by Methylergometrine Maleate stress thallium-201 (201T1) myocardial scintigraphy. Methods: Twenty-five patients with chest pain, all of whom had intact coronary arteries, were studied. After intracoronary Methylergometrine Maleate injection, coronary arteriograms also looked normal in all cases. Thallium-201 myocardial scintigraphy was carried out immediately after intracoronary Methylergometrine Maleate injection in four patients with chest pain. In the remaining 21 patients with chest pain, Methylergometrine Maleate was given intravenously within up to 2 weeks before 201T1 myocardial scintigraphy. Results: In the intracoronary injection study, one patient had chest discomfort after Methylergometrine Maleate injection, and ST-segment elevation was observed on electrocardiogram (ECG). Of the 21 patients with chest pain, 11 patients felt angina-like chest pain after intravenous injection of Methylergometrine Maleate, but their ECGs showed no ischemic changes. Stress 201T1 myocardial scintigrams showed Methylergometrine Maleate-induced perfusion defects with complete redistribution in 3 of 4 patients in the intracoronary injection study and in 12 of 21 patients in the intravenous injection study. These findings suggest that vasospasm in small coronary arteries caused myocardial ischemia in 15 of 25 patients (60%) with chest pain. Conclusion: Vasospasm in small coronary arteries may be involved in the myocardial ischemia of some patients with chest pain who do not show any large coronary artery vasospasm.
M Yo D Murakami - One of the best experts on this subject based on the ideXlab platform.
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myocardial ischemia due to vasospasm of small coronary arteries detected by Methylergometrine Maleate stress myocardial scintigraphy
Clinical Cardiology, 1999Co-Authors: M Toshio D Shimada, M Yutaka D Ishibashi, M Yo D Murakami, M Kazuya D Sano, M Hironori D Tsukihashi, M Seiji D Okada, M Koichi D Kawakami, M Rinji D MurakamiAbstract:Background: Recently, several case reports have implicated vasospasm of small coronary arteries in vasospastic angina pectoris. Vasospasm of small coronary arteries was also considered from angiographic findings in patients with atypical chest pain. In Syrian hamster, vasospasm in small coronary arteries was considered to be the cause of dilated cardiomyopathy. Hypothesis: This study was undertaken to determine whether vasospasm in small coronary arteries can be induced by Methylergometrine Maleate stress thallium-201 (201T1) myocardial scintigraphy. Methods: Twenty-five patients with chest pain, all of whom had intact coronary arteries, were studied. After intracoronary Methylergometrine Maleate injection, coronary arteriograms also looked normal in all cases. Thallium-201 myocardial scintigraphy was carried out immediately after intracoronary Methylergometrine Maleate injection in four patients with chest pain. In the remaining 21 patients with chest pain, Methylergometrine Maleate was given intravenously within up to 2 weeks before 201T1 myocardial scintigraphy. Results: In the intracoronary injection study, one patient had chest discomfort after Methylergometrine Maleate injection, and ST-segment elevation was observed on electrocardiogram (ECG). Of the 21 patients with chest pain, 11 patients felt angina-like chest pain after intravenous injection of Methylergometrine Maleate, but their ECGs showed no ischemic changes. Stress 201T1 myocardial scintigrams showed Methylergometrine Maleate-induced perfusion defects with complete redistribution in 3 of 4 patients in the intracoronary injection study and in 12 of 21 patients in the intravenous injection study. These findings suggest that vasospasm in small coronary arteries caused myocardial ischemia in 15 of 25 patients (60%) with chest pain. Conclusion: Vasospasm in small coronary arteries may be involved in the myocardial ischemia of some patients with chest pain who do not show any large coronary artery vasospasm.