Microcephaly

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Giovanny Vinicius Araujo De Franca - One of the best experts on this subject based on the ideXlab platform.

  • increase in reported prevalence of Microcephaly in infants born to women living in areas with confirmed zika virus transmission during the first trimester of pregnancy brazil 2015
    Morbidity and Mortality Weekly Report, 2016
    Co-Authors: Wanderson Kleber De Oliveira, Juan Jose Cortezescalante, Wanessa Tenorio Goncalves Holanda De Oliveira, Greice Madeleine Ikeda Do Carmo, Claudio Maierovitch Pessanha Henriques, Giovanini Evelim Coelho, Giovanny Vinicius Araujo De Franca
    Abstract:

    Widespread transmission of Zika virus by Aedes mosquitoes has been recognized in Brazil since late 2014, and in October 2015, an increase in the number of reported cases of Microcephaly was reported to the Brazil Ministry of Health.* By January 2016, a total of 3,530 suspected Microcephaly cases had been reported, many of which occurred in infants born to women who lived in or had visited areas where Zika virus transmission was occurring. Microcephaly surveillance was enhanced in late 2015 by implementing a more sensitive case definition. Based on the peak number of reported cases of Microcephaly, and assuming an average estimated pregnancy duration of 38 weeks in Brazil (1), the first trimester of pregnancy coincided with reports of cases of febrile rash illness compatible with Zika virus disease in pregnant women in Bahia, Paraiba, and Pernambuco states, supporting an association between Zika virus infection during early pregnancy and the occurrence of Microcephaly. Pregnant women in areas where Zika virus transmission is occurring should take steps to avoid mosquito bites. Additional studies are needed to further elucidate the relationship between Zika virus infection in pregnancy and Microcephaly.

  • increase in reported prevalence of Microcephaly in infants born to women living in areas with confirmed zika virus transmission during the first trimester of pregnancy brazil 2015
    Morbidity and Mortality Weekly Report, 2016
    Co-Authors: Wanderson Kleber De Oliveira, Juan Jose Cortezescalante, Wanessa Tenorio Goncalves Holanda De Oliveira, Greice Madeleine Ikeda Do Carmo, Claudio Maierovitch Pessanha Henriques, Giovanini Evelim Coelho, Giovanny Vinicius Araujo De Franca
    Abstract:

    What is already known about this topic? An outbreak of Zika virus disease caused by a flavivirus transmitted by Aedes mosquitoes occurred in Brazil in early 2015. An increase in the prevalence of infants born with Microcephaly has been reported in Brazil since October 2015 in association with clusters of febrile rash illness in pregnant women. What is added by this report? The birth prevalence of Microcephaly in Brazil increased sharply during 2015-2016. The largest increase occurred in the Northeast region where Zika virus transmission was first reported in Brazil. This analysis of 574 cases of Microcephaly detected through a newly established ad hoc Microcephaly surveillance system identified temporal and geospatial evidence linking the occurrence of febrile rash illness consistent with Zika virus disease during the first trimester of pregnancy with the increased birth prevalence of Microcephaly. The prevalence of Microcephaly in 15 states with laboratory-confirmed Zika virus transmission (2.8 cases per 10000 live births) significantly exceeded that in four states without confirmed Zika virus transmission (0.6 per 10000). What are the implications for public health practice? The suggested link between maternal exposure to Zika virus infection during the first trimester of pregnancy and the increased birth prevalence of Microcephaly provide additional evidence for congenital infection with Zika virus. Ongoing surveillance is needed to identify additional cases and to fully elucidate the clinical spectrum of illness. Pregnant women should protect themselves from mosquito bites by wearing protective clothing applying insect repellents and when indoors ensuring that rooms are protected with screens or mosquito nets.

Wanderson Kleber De Oliveira - One of the best experts on this subject based on the ideXlab platform.

  • zika virus infection associated Microcephaly and low yellow fever vaccination coverage in brazil is there any causal link
    Journal of Infection in Developing Countries, 2016
    Co-Authors: Luciano Pamplona De Goes Cavalcanti, Wanderson Kleber De Oliveira, Pedro Luiz Tauil, Carlos Henrique Alencar, Mauro M Teixeira, Jorg Heukelbach
    Abstract:

    Introduction: Since the end of 2014, Zika virus (ZIKV) infection has been rapidly spreading in Brazil. Methodology: To analyze the possible association of yellow fever vaccine with a protective effect against ZIKV-related Microcephaly, the following spatial analyses were performed, using Brazilian municipalities as units: i) yellow fever vaccination coverage in Brazilian municipalities in individuals aged 15-49; ii) reported cases of Microcephaly by municipality; and iii) confirmed cases of Microcephaly related to ZIKV, by municipality. SaTScan software was used to identify clusters of municipalities for high risk of Microcephaly. Results: There were seven significant high risk clusters of confirmed Microcephaly cases, with four of them located in the Northeast where yellow fever vaccination rates were the lowest. The clusters harbored only 2.9% of the total population of Brazil, but 15.2% of confirmed cases of Microcephaly. Conclusion: We hypothesize that pregnant women in regions with high yellow fever vaccination coverage may pose their offspring to lower risk for development of Microcephaly. There is an urgent need for systematic studies to confirm the possible link between low yellow fever vaccination coverage, Zika virus infection and Microcephaly.

  • increase in reported prevalence of Microcephaly in infants born to women living in areas with confirmed zika virus transmission during the first trimester of pregnancy brazil 2015
    Morbidity and Mortality Weekly Report, 2016
    Co-Authors: Wanderson Kleber De Oliveira, Juan Jose Cortezescalante, Wanessa Tenorio Goncalves Holanda De Oliveira, Greice Madeleine Ikeda Do Carmo, Claudio Maierovitch Pessanha Henriques, Giovanini Evelim Coelho, Giovanny Vinicius Araujo De Franca
    Abstract:

    Widespread transmission of Zika virus by Aedes mosquitoes has been recognized in Brazil since late 2014, and in October 2015, an increase in the number of reported cases of Microcephaly was reported to the Brazil Ministry of Health.* By January 2016, a total of 3,530 suspected Microcephaly cases had been reported, many of which occurred in infants born to women who lived in or had visited areas where Zika virus transmission was occurring. Microcephaly surveillance was enhanced in late 2015 by implementing a more sensitive case definition. Based on the peak number of reported cases of Microcephaly, and assuming an average estimated pregnancy duration of 38 weeks in Brazil (1), the first trimester of pregnancy coincided with reports of cases of febrile rash illness compatible with Zika virus disease in pregnant women in Bahia, Paraiba, and Pernambuco states, supporting an association between Zika virus infection during early pregnancy and the occurrence of Microcephaly. Pregnant women in areas where Zika virus transmission is occurring should take steps to avoid mosquito bites. Additional studies are needed to further elucidate the relationship between Zika virus infection in pregnancy and Microcephaly.

  • increase in reported prevalence of Microcephaly in infants born to women living in areas with confirmed zika virus transmission during the first trimester of pregnancy brazil 2015
    Morbidity and Mortality Weekly Report, 2016
    Co-Authors: Wanderson Kleber De Oliveira, Juan Jose Cortezescalante, Wanessa Tenorio Goncalves Holanda De Oliveira, Greice Madeleine Ikeda Do Carmo, Claudio Maierovitch Pessanha Henriques, Giovanini Evelim Coelho, Giovanny Vinicius Araujo De Franca
    Abstract:

    What is already known about this topic? An outbreak of Zika virus disease caused by a flavivirus transmitted by Aedes mosquitoes occurred in Brazil in early 2015. An increase in the prevalence of infants born with Microcephaly has been reported in Brazil since October 2015 in association with clusters of febrile rash illness in pregnant women. What is added by this report? The birth prevalence of Microcephaly in Brazil increased sharply during 2015-2016. The largest increase occurred in the Northeast region where Zika virus transmission was first reported in Brazil. This analysis of 574 cases of Microcephaly detected through a newly established ad hoc Microcephaly surveillance system identified temporal and geospatial evidence linking the occurrence of febrile rash illness consistent with Zika virus disease during the first trimester of pregnancy with the increased birth prevalence of Microcephaly. The prevalence of Microcephaly in 15 states with laboratory-confirmed Zika virus transmission (2.8 cases per 10000 live births) significantly exceeded that in four states without confirmed Zika virus transmission (0.6 per 10000). What are the implications for public health practice? The suggested link between maternal exposure to Zika virus infection during the first trimester of pregnancy and the increased birth prevalence of Microcephaly provide additional evidence for congenital infection with Zika virus. Ongoing surveillance is needed to identify additional cases and to fully elucidate the clinical spectrum of illness. Pregnant women should protect themselves from mosquito bites by wearing protective clothing applying insect repellents and when indoors ensuring that rooms are protected with screens or mosquito nets.

Juan Jose Cortezescalante - One of the best experts on this subject based on the ideXlab platform.

  • increase in reported prevalence of Microcephaly in infants born to women living in areas with confirmed zika virus transmission during the first trimester of pregnancy brazil 2015
    Morbidity and Mortality Weekly Report, 2016
    Co-Authors: Wanderson Kleber De Oliveira, Juan Jose Cortezescalante, Wanessa Tenorio Goncalves Holanda De Oliveira, Greice Madeleine Ikeda Do Carmo, Claudio Maierovitch Pessanha Henriques, Giovanini Evelim Coelho, Giovanny Vinicius Araujo De Franca
    Abstract:

    Widespread transmission of Zika virus by Aedes mosquitoes has been recognized in Brazil since late 2014, and in October 2015, an increase in the number of reported cases of Microcephaly was reported to the Brazil Ministry of Health.* By January 2016, a total of 3,530 suspected Microcephaly cases had been reported, many of which occurred in infants born to women who lived in or had visited areas where Zika virus transmission was occurring. Microcephaly surveillance was enhanced in late 2015 by implementing a more sensitive case definition. Based on the peak number of reported cases of Microcephaly, and assuming an average estimated pregnancy duration of 38 weeks in Brazil (1), the first trimester of pregnancy coincided with reports of cases of febrile rash illness compatible with Zika virus disease in pregnant women in Bahia, Paraiba, and Pernambuco states, supporting an association between Zika virus infection during early pregnancy and the occurrence of Microcephaly. Pregnant women in areas where Zika virus transmission is occurring should take steps to avoid mosquito bites. Additional studies are needed to further elucidate the relationship between Zika virus infection in pregnancy and Microcephaly.

  • increase in reported prevalence of Microcephaly in infants born to women living in areas with confirmed zika virus transmission during the first trimester of pregnancy brazil 2015
    Morbidity and Mortality Weekly Report, 2016
    Co-Authors: Wanderson Kleber De Oliveira, Juan Jose Cortezescalante, Wanessa Tenorio Goncalves Holanda De Oliveira, Greice Madeleine Ikeda Do Carmo, Claudio Maierovitch Pessanha Henriques, Giovanini Evelim Coelho, Giovanny Vinicius Araujo De Franca
    Abstract:

    What is already known about this topic? An outbreak of Zika virus disease caused by a flavivirus transmitted by Aedes mosquitoes occurred in Brazil in early 2015. An increase in the prevalence of infants born with Microcephaly has been reported in Brazil since October 2015 in association with clusters of febrile rash illness in pregnant women. What is added by this report? The birth prevalence of Microcephaly in Brazil increased sharply during 2015-2016. The largest increase occurred in the Northeast region where Zika virus transmission was first reported in Brazil. This analysis of 574 cases of Microcephaly detected through a newly established ad hoc Microcephaly surveillance system identified temporal and geospatial evidence linking the occurrence of febrile rash illness consistent with Zika virus disease during the first trimester of pregnancy with the increased birth prevalence of Microcephaly. The prevalence of Microcephaly in 15 states with laboratory-confirmed Zika virus transmission (2.8 cases per 10000 live births) significantly exceeded that in four states without confirmed Zika virus transmission (0.6 per 10000). What are the implications for public health practice? The suggested link between maternal exposure to Zika virus infection during the first trimester of pregnancy and the increased birth prevalence of Microcephaly provide additional evidence for congenital infection with Zika virus. Ongoing surveillance is needed to identify additional cases and to fully elucidate the clinical spectrum of illness. Pregnant women should protect themselves from mosquito bites by wearing protective clothing applying insect repellents and when indoors ensuring that rooms are protected with screens or mosquito nets.

Wanessa Tenorio Goncalves Holanda De Oliveira - One of the best experts on this subject based on the ideXlab platform.

  • increase in reported prevalence of Microcephaly in infants born to women living in areas with confirmed zika virus transmission during the first trimester of pregnancy brazil 2015
    Morbidity and Mortality Weekly Report, 2016
    Co-Authors: Wanderson Kleber De Oliveira, Juan Jose Cortezescalante, Wanessa Tenorio Goncalves Holanda De Oliveira, Greice Madeleine Ikeda Do Carmo, Claudio Maierovitch Pessanha Henriques, Giovanini Evelim Coelho, Giovanny Vinicius Araujo De Franca
    Abstract:

    Widespread transmission of Zika virus by Aedes mosquitoes has been recognized in Brazil since late 2014, and in October 2015, an increase in the number of reported cases of Microcephaly was reported to the Brazil Ministry of Health.* By January 2016, a total of 3,530 suspected Microcephaly cases had been reported, many of which occurred in infants born to women who lived in or had visited areas where Zika virus transmission was occurring. Microcephaly surveillance was enhanced in late 2015 by implementing a more sensitive case definition. Based on the peak number of reported cases of Microcephaly, and assuming an average estimated pregnancy duration of 38 weeks in Brazil (1), the first trimester of pregnancy coincided with reports of cases of febrile rash illness compatible with Zika virus disease in pregnant women in Bahia, Paraiba, and Pernambuco states, supporting an association between Zika virus infection during early pregnancy and the occurrence of Microcephaly. Pregnant women in areas where Zika virus transmission is occurring should take steps to avoid mosquito bites. Additional studies are needed to further elucidate the relationship between Zika virus infection in pregnancy and Microcephaly.

  • increase in reported prevalence of Microcephaly in infants born to women living in areas with confirmed zika virus transmission during the first trimester of pregnancy brazil 2015
    Morbidity and Mortality Weekly Report, 2016
    Co-Authors: Wanderson Kleber De Oliveira, Juan Jose Cortezescalante, Wanessa Tenorio Goncalves Holanda De Oliveira, Greice Madeleine Ikeda Do Carmo, Claudio Maierovitch Pessanha Henriques, Giovanini Evelim Coelho, Giovanny Vinicius Araujo De Franca
    Abstract:

    What is already known about this topic? An outbreak of Zika virus disease caused by a flavivirus transmitted by Aedes mosquitoes occurred in Brazil in early 2015. An increase in the prevalence of infants born with Microcephaly has been reported in Brazil since October 2015 in association with clusters of febrile rash illness in pregnant women. What is added by this report? The birth prevalence of Microcephaly in Brazil increased sharply during 2015-2016. The largest increase occurred in the Northeast region where Zika virus transmission was first reported in Brazil. This analysis of 574 cases of Microcephaly detected through a newly established ad hoc Microcephaly surveillance system identified temporal and geospatial evidence linking the occurrence of febrile rash illness consistent with Zika virus disease during the first trimester of pregnancy with the increased birth prevalence of Microcephaly. The prevalence of Microcephaly in 15 states with laboratory-confirmed Zika virus transmission (2.8 cases per 10000 live births) significantly exceeded that in four states without confirmed Zika virus transmission (0.6 per 10000). What are the implications for public health practice? The suggested link between maternal exposure to Zika virus infection during the first trimester of pregnancy and the increased birth prevalence of Microcephaly provide additional evidence for congenital infection with Zika virus. Ongoing surveillance is needed to identify additional cases and to fully elucidate the clinical spectrum of illness. Pregnant women should protect themselves from mosquito bites by wearing protective clothing applying insect repellents and when indoors ensuring that rooms are protected with screens or mosquito nets.

Greice Madeleine Ikeda Do Carmo - One of the best experts on this subject based on the ideXlab platform.

  • increase in reported prevalence of Microcephaly in infants born to women living in areas with confirmed zika virus transmission during the first trimester of pregnancy brazil 2015
    Morbidity and Mortality Weekly Report, 2016
    Co-Authors: Wanderson Kleber De Oliveira, Juan Jose Cortezescalante, Wanessa Tenorio Goncalves Holanda De Oliveira, Greice Madeleine Ikeda Do Carmo, Claudio Maierovitch Pessanha Henriques, Giovanini Evelim Coelho, Giovanny Vinicius Araujo De Franca
    Abstract:

    Widespread transmission of Zika virus by Aedes mosquitoes has been recognized in Brazil since late 2014, and in October 2015, an increase in the number of reported cases of Microcephaly was reported to the Brazil Ministry of Health.* By January 2016, a total of 3,530 suspected Microcephaly cases had been reported, many of which occurred in infants born to women who lived in or had visited areas where Zika virus transmission was occurring. Microcephaly surveillance was enhanced in late 2015 by implementing a more sensitive case definition. Based on the peak number of reported cases of Microcephaly, and assuming an average estimated pregnancy duration of 38 weeks in Brazil (1), the first trimester of pregnancy coincided with reports of cases of febrile rash illness compatible with Zika virus disease in pregnant women in Bahia, Paraiba, and Pernambuco states, supporting an association between Zika virus infection during early pregnancy and the occurrence of Microcephaly. Pregnant women in areas where Zika virus transmission is occurring should take steps to avoid mosquito bites. Additional studies are needed to further elucidate the relationship between Zika virus infection in pregnancy and Microcephaly.

  • increase in reported prevalence of Microcephaly in infants born to women living in areas with confirmed zika virus transmission during the first trimester of pregnancy brazil 2015
    Morbidity and Mortality Weekly Report, 2016
    Co-Authors: Wanderson Kleber De Oliveira, Juan Jose Cortezescalante, Wanessa Tenorio Goncalves Holanda De Oliveira, Greice Madeleine Ikeda Do Carmo, Claudio Maierovitch Pessanha Henriques, Giovanini Evelim Coelho, Giovanny Vinicius Araujo De Franca
    Abstract:

    What is already known about this topic? An outbreak of Zika virus disease caused by a flavivirus transmitted by Aedes mosquitoes occurred in Brazil in early 2015. An increase in the prevalence of infants born with Microcephaly has been reported in Brazil since October 2015 in association with clusters of febrile rash illness in pregnant women. What is added by this report? The birth prevalence of Microcephaly in Brazil increased sharply during 2015-2016. The largest increase occurred in the Northeast region where Zika virus transmission was first reported in Brazil. This analysis of 574 cases of Microcephaly detected through a newly established ad hoc Microcephaly surveillance system identified temporal and geospatial evidence linking the occurrence of febrile rash illness consistent with Zika virus disease during the first trimester of pregnancy with the increased birth prevalence of Microcephaly. The prevalence of Microcephaly in 15 states with laboratory-confirmed Zika virus transmission (2.8 cases per 10000 live births) significantly exceeded that in four states without confirmed Zika virus transmission (0.6 per 10000). What are the implications for public health practice? The suggested link between maternal exposure to Zika virus infection during the first trimester of pregnancy and the increased birth prevalence of Microcephaly provide additional evidence for congenital infection with Zika virus. Ongoing surveillance is needed to identify additional cases and to fully elucidate the clinical spectrum of illness. Pregnant women should protect themselves from mosquito bites by wearing protective clothing applying insect repellents and when indoors ensuring that rooms are protected with screens or mosquito nets.