The Experts below are selected from a list of 48 Experts worldwide ranked by ideXlab platform

H. Subramanian - One of the best experts on this subject based on the ideXlab platform.

R. Radhika - One of the best experts on this subject based on the ideXlab platform.

Relja Beck - One of the best experts on this subject based on the ideXlab platform.

  • Dirofilaria repens microfilaremia in humans: Case description and literature review
    'Elsevier BV', 2021
    Co-Authors: Ana Pupić-bakrač, Jure Pupić-bakrač, Ana Beck, Daria Jurković, Adam Polkinghorne, Relja Beck
    Abstract:

    Introduction: Dirofilaria repens is a vector-borne filaroid helminth of carnivorous animals, primarily domesticated dogs. Humans are considered to be accidental hosts in which D. repens rarely reach sexual maturity but induce local inflammation, mainly in subcutaneous and ocular tissues. Methods: In the current study, we present the detection of multiple adults of D. repens, endosymbiont Wolbachia sp. and microfilariae by molecular analysis in peripheral tissues and bloodstream of a human host. A subsequent meta-analysis of published literature identified 21 cases of human infection with adult D. repens producing microfilariae. Results: Within the study population, there were 13 (59.09%) males, eight (36.36%) females and, in one (4.55%) case, sex was not reported. A total of 11 (50.00%) cases had subcutaneous dirofilariasis, six (27.27%) had ocular dirofiliariasis, with single cases (4.55% each) of genital, mammary, lymphatic and a combination of subcutaneous and pulmonary dirofilariasis described. In one (4.55%) case, the primary anatomical site of adult D. repens could not be found. D. repens microfilariae were detected in the local tissue (local Microfilariasis) in 11 (50.00%) cases and the peripheral blood (microfilaremia) in 11 (50.50%) cases. Final identification of D. repens microfilariae was based on morphological detection in 14 (63.64%) cases, and molecular detection in eight (36.36%) cases. Conclusion: The results of this study suggest that humans may act as a final host for D. repens, however its role as a source of D. repens infection is less clear

Paolo Tarsia - One of the best experts on this subject based on the ideXlab platform.

  • transfusional mansonella perstans Microfilariasis
    Parassitologia, 2003
    Co-Authors: Enrico Rino Bregani, Laurent Balzarini, Chiara Ghiringhelli, Paolo Tarsia
    Abstract:

    : Mansonella perstans filariasis is widely distributed across the center of Africa and equatorial America. We describe a case of post-transfusional M. perstans Microfilariasis in a young child, affected with severe Plasmodium falciparum malaria, admitted in Goundi Hospital in South of Chad. A decrease of M. perstans Microfilariasis in the patient's blood was observed, with no subsequent development of either clinical symptoms or eosinophilia. We suggest that, in endemic areas, transfused M. perstans microfilariae may be cleared from the blood over relatively short periods of time. It is likely that only adult worms are responsible for symptoms and eosinophilia, whereas microfilariae in the bloodstream are unable to give clinical manifestations.

Thomas Namiki - One of the best experts on this subject based on the ideXlab platform.