The Experts below are selected from a list of 315 Experts worldwide ranked by ideXlab platform

Norio Wake - One of the best experts on this subject based on the ideXlab platform.

  • Abnormal fetal movements, Micrognathia and pulmonary hypoplasia: a case report. Abnormal fetal movements
    BMC pregnancy and childbirth, 2010
    Co-Authors: Seiichi Morokuma, Ai Anami, Kiyomi Tsukimori, Kotaro Fukushima, Norio Wake
    Abstract:

    Background: Micrognathia is a facial malformation characterized by mandibular hypoplasia and a small, receding chin that fails to maintain the tongue in a forward position. We previously reported a system of prenatal screening that we developed to identify fetuses with compromised central nervous system function by observing fetal behavior. In this paper we report the case of a preterm infant with Micrognathia and pulmonary hypoplasia who presented abnormal fetal movements. Case presentation: A 27-year-old Japanese primigravida at 33 weeks of gestation was referred to our hospital. Ultrasonographic examination revealed clinical polyhydramnios. Micrognathia was evident on midsagittal and 3 D scan. The lung area was less than the mean -2.0 standard deviations for the gestational age. The infant had mandibular hypoplasia and glossoptosis. After emergency cesarean delivery for non-reasuring fetal status, required immediate tracheostomy and cardiopulmonary resuscitation with mechanical ventilatory support. However, the infant’s cardiopulmonary condition did not improve and she died 21 hours after birth. Conclusions: The findings of our ultrasound exam are suggestive of brain dysfunction. The observation of fetal behavior appears to be effective for the prediction of prognosis of cases with Micrognathia.

  • abnormal fetal movements Micrognathia and pulmonary hypoplasia a case report abnormal fetal movements
    BMC Pregnancy and Childbirth, 2010
    Co-Authors: Seiichi Morokuma, Ai Anami, Kiyomi Tsukimori, Kotaro Fukushima, Norio Wake
    Abstract:

    Background Micrognathia is a facial malformation characterized by mandibular hypoplasia and a small, receding chin that fails to maintain the tongue in a forward position. We previously reported a system of prenatal screening that we developed to identify fetuses with compromised central nervous system function by observing fetal behavior. In this paper we report the case of a preterm infant with Micrognathia and pulmonary hypoplasia who presented abnormal fetal movements.

Seiichi Morokuma - One of the best experts on this subject based on the ideXlab platform.

  • Abnormal fetal movements, Micrognathia and pulmonary hypoplasia: a case report. Abnormal fetal movements
    BMC pregnancy and childbirth, 2010
    Co-Authors: Seiichi Morokuma, Ai Anami, Kiyomi Tsukimori, Kotaro Fukushima, Norio Wake
    Abstract:

    Background: Micrognathia is a facial malformation characterized by mandibular hypoplasia and a small, receding chin that fails to maintain the tongue in a forward position. We previously reported a system of prenatal screening that we developed to identify fetuses with compromised central nervous system function by observing fetal behavior. In this paper we report the case of a preterm infant with Micrognathia and pulmonary hypoplasia who presented abnormal fetal movements. Case presentation: A 27-year-old Japanese primigravida at 33 weeks of gestation was referred to our hospital. Ultrasonographic examination revealed clinical polyhydramnios. Micrognathia was evident on midsagittal and 3 D scan. The lung area was less than the mean -2.0 standard deviations for the gestational age. The infant had mandibular hypoplasia and glossoptosis. After emergency cesarean delivery for non-reasuring fetal status, required immediate tracheostomy and cardiopulmonary resuscitation with mechanical ventilatory support. However, the infant’s cardiopulmonary condition did not improve and she died 21 hours after birth. Conclusions: The findings of our ultrasound exam are suggestive of brain dysfunction. The observation of fetal behavior appears to be effective for the prediction of prognosis of cases with Micrognathia.

  • abnormal fetal movements Micrognathia and pulmonary hypoplasia a case report abnormal fetal movements
    BMC Pregnancy and Childbirth, 2010
    Co-Authors: Seiichi Morokuma, Ai Anami, Kiyomi Tsukimori, Kotaro Fukushima, Norio Wake
    Abstract:

    Background Micrognathia is a facial malformation characterized by mandibular hypoplasia and a small, receding chin that fails to maintain the tongue in a forward position. We previously reported a system of prenatal screening that we developed to identify fetuses with compromised central nervous system function by observing fetal behavior. In this paper we report the case of a preterm infant with Micrognathia and pulmonary hypoplasia who presented abnormal fetal movements.

Xiao-xia Wang - One of the best experts on this subject based on the ideXlab platform.

  • The treatment of mandibular Micrognathia secondary to temporomandibular joint ankylosis with distraction osteogenesis
    Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery, 2012
    Co-Authors: Cheng Liang, Xing Wang, Xiao-xia Wang
    Abstract:

    Objective To evaluate the clinical effect of distraction osteogenesis for patients with mandibular Micrognathia secondary to temporomandibular joint(TMJ) ankylosis.Methods 43 patients (aged from 2 to 61 years old) with mandibular Micrognathia were treated with mandibular distraction osteogenesis.Two types of mechanical distraction were utilized in this study.Ten patients (age ranged from 2 to 16 years old,mean age 7.6 years old) with severe Micrognathia underwent bilateral mandibular distraction with rigid external distraction (RED) device.Other 33 patients were treated with unilateral(6 cases) or bilateral (27 cases) mandibular distraction using internal distraction device.Distraction was started on the 4th to 8 th day after operation and distraction rate was 0.25 mm every time,four times a day.Distractor was removed after 3 to 6 months of consolidation period.Results Eighty sides of mandible in 43patients were lengthened.The mean distraction distance was 23.2 mm (ranged from 14 to 35 mm).After distraction,the average posterior airway space(PAS) was enlarged from 4.9 mm to 10.4 mm and average angle of sella-nasion-point B(SNB) was increased from 64.2°to 74.5°.The apnea hypopnea index(AHI) was decrease significantly.The profile was improved and OSA was improved effectively in each patient.No complication occurred during treatment.No persistent numbness of lower lip was observed.All patients were satisfied with the results.After a mean follow-up period of 20.3 months(5 to 103 months),the result was stable and no obvious relapse of Micrognathia was observed.Conclusions Distraction osteogenesis is an effective way in correction of mandibular Micrognathia secondary to TMJ ankylosis.RED is a new method for treatment of children and adolescence with severe mandibular Micrognathia.The procedure is simple and safe with stable result. Key words: Distraction, osteogenesis;  Temporomandibular joint ankylosis;  Micrognathism

  • Clinical study of simultaneous correction of unilateral temporomandibular joint ankylosis and mandibular Micrognathia with internal distraction osteogenesis
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2007
    Co-Authors: Cheng Liang, Xing Wang, Xiao-xia Wang
    Abstract:

    OBJECTIVE To observe the clinical results in correction of unilateral temporomandibular joint(TMJ) ankylosis accompanying with mandibular Micrognathia using internal distraction osteogenesis simultaneously. METHODS Seven adult patients of unilateral TMJ ankylosis accompanying with mandibular Micrognathia (13 sides of mandibular body) were treated simultaneously with internal distraction osteogenesis. Obstructive sleep apnea and hypopnea syndrome(OSAHS) was diagnosed in all patients preoperatively. The treatment includes distraction osteogenesis of mandibular body and transport distraction osteogenesis for TMJ arthroplasty at the same time. Distraction was started on the 6th to 8th day after operation. The distraction rhythm and rate was one mm a day operated in 4 separate times. The patients underwent active mouth opening postoperatively. Distractors were kept in place for 3-5 months after completion of distraction and then removed. Mean distraction distance of the 13 sides of mandibular body was 17.1mm(ranged from 14 to 20 mm) and that of the 7 sides of TMJ was 16.4mm(ranged from 15 to 20mm). RESULTS After treatment, Micrognathia of the 7 patients was corrected. OSAHS was cured in 6 patients. The mean range of mouth opening was increased from 8.1 mm to 39.9 mm and bone formation in the distraction gaps was observed. The mean following-up period was 34.3 months(ranged from 18 to 51 months). No recurrence of TMJ ankylosis or Micrognathia was occurred. CONCLUSION Unilateral TMJ ankylosis accompanying with Micrognathia and OSAHS can be treated effectively by distraction osteogenesis simultaneously. The operation is simple with low risk. The course of treatment can be simplified and the operation times can be reduced.

  • Treatment of severe Micrognathia accompanying obstructive sleep apnea hypopnea syndrome with rigid external distractor
    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 2007
    Co-Authors: Xing Wang, Cheng Liang, Xiao-xia Wang
    Abstract:

    OBJECTIVE To approach the treatment of severe Micrognathia accompanying obstructive sleep apnea hypopnea syndrome (OSAHS) with rigid external distractor (RED) in children. METHODS Six cases patients (4 males, 2 females) aged between 1.5 and 14 years, were diagnosed as ankylosis of temporomandibular joint severe Micrognathia, and OSAHS. Under the nasal intubation and general anesthesia, the surgical procedures were performed by submandibular approach and osteotomy was done in mandible body. Mini plate was fixed and connected to RED. The distraction procedure was carried out RESULTS Patients' profile, posterior airway space, and the results of polysomnography were improved significantly. There were no complications. Four months after removing the RED, the new bone was well formed. CONCLUSIONS RED technique has advantages of uncomplicated procedures, high quality of new bone formation, and accurate regulation in the treatment of Micrognathia. It is especially suitable for the treatment of children with severe Micrognathia whose mandibular body is too small to insert the internal distractor.

  • Distraction osteogenesis in correction of Micrognathia accompanying obstructive sleep apnea syndrome.
    Plastic and reconstructive surgery, 2003
    Co-Authors: Xing Wang, Cheng Liang, Xiao-xia Wang, Ye Lin
    Abstract:

    To evaluate the effect of distraction osteogenesis in correction of Micrognathia accompanying obstructive sleep apnea syndrome, a total of 28 patients with different severities of obstructive sleep apnea syndrome underwent mandibular distraction osteogenesis. A total of 51 distraction devices were placed for bilateral distraction in 23 patients and for unilateral distraction in five patients. The mean age of patients was 21.2 years (range, 3 to 60 years). Eleven patients had Micrognathia accompanying obstructive sleep apnea syndrome secondary to bilateral temporomandibular joint ankylosis, and 10 patients had Micrognathia accompanying obstructive sleep apnea syndrome secondary to unilateral temporomandibular joint ankylosis. Three patients had developmental Micrognathia accompanying obstructive sleep apnea syndrome. The other four patients had Micrognathia and concomitant obstructive sleep apnea syndrome induced by trauma, infection, or tumor resection. Each patient had been evaluated preoperatively and postoperatively with cephalometry and polysomnography. Mandible advancement ranged from 9 to 30 mm (average, 20.4 mm) and was successfully achieved after distraction. Fine new bone formed in the distraction gap when the distraction devices were removed 3 to 4 months after distraction was completed. No infection or other complications occurred in any patients. Complete curative effects were achieved in nine severe, six moderate, and eight mild obstructive sleep apnea syndrome patients after distraction, and the other five patients had been improved to the mild level. After distraction was completed, the posterior airway space was increased on average from 4.6 mm to 12.5 mm and the sella-nasion-point B angle Was increased on average from 66 degrees to 75 degrees on cephalometric studies. The polysomnographic examination showed that the apnea hypopnea index was lowered on average from 58.0 to 3.15, and the lowest oxygen saturation was increased on average from 77 percent to 90.3 percent after distraction was completed. The follow-up period was 3 to 61 months (average, 18.1 months). The curative effect was stable and no relapse occurred. Therefore, the authors conclude that mandibular distraction osteogenesis is an effective method for correcting Micrognathia accompanying obstructive sleep apnea syndrome. Compared with other current routine surgical procedures, it has many advantages, such as low risk, simple manipulation, high curative rate, low relapse rate, and stable result. It is presently the most effective method for the treatment of this difficult and complicated disorder.

  • Distraction osteogenesis in correction of mandibular Micrognathia accompanying obstructive sleep apnea syndrome
    Zhonghua yi xue za zhi, 2001
    Co-Authors: Xiao-xia Wang, Cheng Liang, B Yin
    Abstract:

    OBJECTIVE: To evaluate the effect of distraction osteogenesis in correction of mandibular Micrognathia accompanying obstructive sleep apnea syndrome (OSAS). METHODS: A total of 15 patients, aged 9 to 43 years, 11 males and 4 females, were treated. 7 patients suffered from bilateral ankylosis of temporo manclibular joint inducing severe mandibular Micrognathia and accompanying severe OSAS. 3 cases suffered from unilateral TMJ ankylosis with OSAS. 3 patients suffered from congenital developmental Micrognathia with OSAS. 2 cases were caused by trauma. Among the 15 patients, 12 were treated by synchronous bilateral mandibular distraction, 3 patients were distracted unilaterally. Every patient had been evaluated pre- and postoperatively with cephalometry and polysomnography. RESULTS: The minimum distance of distraction was 9 mm, the maximum was 30 mm, with a mean of 20.4 mm, in mandible of 15 patients with 27 sides. The distraction process was smooth in all the cases. The osteogenesis was good, without infection and other complications. Complete curative effect was achieved in 4 severe, 3 moderate, and 4 mild cases. The posterior airway space was increased from averaged 4.5 mm preoperatively to 12.4 mm. The increase of SNB angle was from preoperative 66 degrees to 75 degrees on average postoperatively. The vast majority of the patients had their subjective symptoms alleviated gradually or disappeared completely. The results were stable without relapse during a follow-up period of 12 months. CONCLUSION: The distraction osteogenesis can not only be used to effectively correct severe mandibular Micrognathia deformity, but also can cure its accompanying OSAS. The procedure is simple, with low risk, high curative rate, low relapse rate, and stable result. Up to now, it is the most effective method in the treatment of this difficult and complicated kind of disorder.

Xing Wang - One of the best experts on this subject based on the ideXlab platform.

  • The treatment of mandibular Micrognathia secondary to temporomandibular joint ankylosis with distraction osteogenesis
    Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery, 2012
    Co-Authors: Cheng Liang, Xing Wang, Xiao-xia Wang
    Abstract:

    Objective To evaluate the clinical effect of distraction osteogenesis for patients with mandibular Micrognathia secondary to temporomandibular joint(TMJ) ankylosis.Methods 43 patients (aged from 2 to 61 years old) with mandibular Micrognathia were treated with mandibular distraction osteogenesis.Two types of mechanical distraction were utilized in this study.Ten patients (age ranged from 2 to 16 years old,mean age 7.6 years old) with severe Micrognathia underwent bilateral mandibular distraction with rigid external distraction (RED) device.Other 33 patients were treated with unilateral(6 cases) or bilateral (27 cases) mandibular distraction using internal distraction device.Distraction was started on the 4th to 8 th day after operation and distraction rate was 0.25 mm every time,four times a day.Distractor was removed after 3 to 6 months of consolidation period.Results Eighty sides of mandible in 43patients were lengthened.The mean distraction distance was 23.2 mm (ranged from 14 to 35 mm).After distraction,the average posterior airway space(PAS) was enlarged from 4.9 mm to 10.4 mm and average angle of sella-nasion-point B(SNB) was increased from 64.2°to 74.5°.The apnea hypopnea index(AHI) was decrease significantly.The profile was improved and OSA was improved effectively in each patient.No complication occurred during treatment.No persistent numbness of lower lip was observed.All patients were satisfied with the results.After a mean follow-up period of 20.3 months(5 to 103 months),the result was stable and no obvious relapse of Micrognathia was observed.Conclusions Distraction osteogenesis is an effective way in correction of mandibular Micrognathia secondary to TMJ ankylosis.RED is a new method for treatment of children and adolescence with severe mandibular Micrognathia.The procedure is simple and safe with stable result. Key words: Distraction, osteogenesis;  Temporomandibular joint ankylosis;  Micrognathism

  • Clinical study of simultaneous correction of unilateral temporomandibular joint ankylosis and mandibular Micrognathia with internal distraction osteogenesis
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2007
    Co-Authors: Cheng Liang, Xing Wang, Xiao-xia Wang
    Abstract:

    OBJECTIVE To observe the clinical results in correction of unilateral temporomandibular joint(TMJ) ankylosis accompanying with mandibular Micrognathia using internal distraction osteogenesis simultaneously. METHODS Seven adult patients of unilateral TMJ ankylosis accompanying with mandibular Micrognathia (13 sides of mandibular body) were treated simultaneously with internal distraction osteogenesis. Obstructive sleep apnea and hypopnea syndrome(OSAHS) was diagnosed in all patients preoperatively. The treatment includes distraction osteogenesis of mandibular body and transport distraction osteogenesis for TMJ arthroplasty at the same time. Distraction was started on the 6th to 8th day after operation. The distraction rhythm and rate was one mm a day operated in 4 separate times. The patients underwent active mouth opening postoperatively. Distractors were kept in place for 3-5 months after completion of distraction and then removed. Mean distraction distance of the 13 sides of mandibular body was 17.1mm(ranged from 14 to 20 mm) and that of the 7 sides of TMJ was 16.4mm(ranged from 15 to 20mm). RESULTS After treatment, Micrognathia of the 7 patients was corrected. OSAHS was cured in 6 patients. The mean range of mouth opening was increased from 8.1 mm to 39.9 mm and bone formation in the distraction gaps was observed. The mean following-up period was 34.3 months(ranged from 18 to 51 months). No recurrence of TMJ ankylosis or Micrognathia was occurred. CONCLUSION Unilateral TMJ ankylosis accompanying with Micrognathia and OSAHS can be treated effectively by distraction osteogenesis simultaneously. The operation is simple with low risk. The course of treatment can be simplified and the operation times can be reduced.

  • Treatment of severe Micrognathia accompanying obstructive sleep apnea hypopnea syndrome with rigid external distractor
    Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology, 2007
    Co-Authors: Xing Wang, Cheng Liang, Xiao-xia Wang
    Abstract:

    OBJECTIVE To approach the treatment of severe Micrognathia accompanying obstructive sleep apnea hypopnea syndrome (OSAHS) with rigid external distractor (RED) in children. METHODS Six cases patients (4 males, 2 females) aged between 1.5 and 14 years, were diagnosed as ankylosis of temporomandibular joint severe Micrognathia, and OSAHS. Under the nasal intubation and general anesthesia, the surgical procedures were performed by submandibular approach and osteotomy was done in mandible body. Mini plate was fixed and connected to RED. The distraction procedure was carried out RESULTS Patients' profile, posterior airway space, and the results of polysomnography were improved significantly. There were no complications. Four months after removing the RED, the new bone was well formed. CONCLUSIONS RED technique has advantages of uncomplicated procedures, high quality of new bone formation, and accurate regulation in the treatment of Micrognathia. It is especially suitable for the treatment of children with severe Micrognathia whose mandibular body is too small to insert the internal distractor.

  • Distraction osteogenesis in correction of Micrognathia accompanying obstructive sleep apnea syndrome.
    Plastic and reconstructive surgery, 2003
    Co-Authors: Xing Wang, Cheng Liang, Xiao-xia Wang, Ye Lin
    Abstract:

    To evaluate the effect of distraction osteogenesis in correction of Micrognathia accompanying obstructive sleep apnea syndrome, a total of 28 patients with different severities of obstructive sleep apnea syndrome underwent mandibular distraction osteogenesis. A total of 51 distraction devices were placed for bilateral distraction in 23 patients and for unilateral distraction in five patients. The mean age of patients was 21.2 years (range, 3 to 60 years). Eleven patients had Micrognathia accompanying obstructive sleep apnea syndrome secondary to bilateral temporomandibular joint ankylosis, and 10 patients had Micrognathia accompanying obstructive sleep apnea syndrome secondary to unilateral temporomandibular joint ankylosis. Three patients had developmental Micrognathia accompanying obstructive sleep apnea syndrome. The other four patients had Micrognathia and concomitant obstructive sleep apnea syndrome induced by trauma, infection, or tumor resection. Each patient had been evaluated preoperatively and postoperatively with cephalometry and polysomnography. Mandible advancement ranged from 9 to 30 mm (average, 20.4 mm) and was successfully achieved after distraction. Fine new bone formed in the distraction gap when the distraction devices were removed 3 to 4 months after distraction was completed. No infection or other complications occurred in any patients. Complete curative effects were achieved in nine severe, six moderate, and eight mild obstructive sleep apnea syndrome patients after distraction, and the other five patients had been improved to the mild level. After distraction was completed, the posterior airway space was increased on average from 4.6 mm to 12.5 mm and the sella-nasion-point B angle Was increased on average from 66 degrees to 75 degrees on cephalometric studies. The polysomnographic examination showed that the apnea hypopnea index was lowered on average from 58.0 to 3.15, and the lowest oxygen saturation was increased on average from 77 percent to 90.3 percent after distraction was completed. The follow-up period was 3 to 61 months (average, 18.1 months). The curative effect was stable and no relapse occurred. Therefore, the authors conclude that mandibular distraction osteogenesis is an effective method for correcting Micrognathia accompanying obstructive sleep apnea syndrome. Compared with other current routine surgical procedures, it has many advantages, such as low risk, simple manipulation, high curative rate, low relapse rate, and stable result. It is presently the most effective method for the treatment of this difficult and complicated disorder.

Kiyomi Tsukimori - One of the best experts on this subject based on the ideXlab platform.

  • Abnormal fetal movements, Micrognathia and pulmonary hypoplasia: a case report. Abnormal fetal movements
    BMC pregnancy and childbirth, 2010
    Co-Authors: Seiichi Morokuma, Ai Anami, Kiyomi Tsukimori, Kotaro Fukushima, Norio Wake
    Abstract:

    Background: Micrognathia is a facial malformation characterized by mandibular hypoplasia and a small, receding chin that fails to maintain the tongue in a forward position. We previously reported a system of prenatal screening that we developed to identify fetuses with compromised central nervous system function by observing fetal behavior. In this paper we report the case of a preterm infant with Micrognathia and pulmonary hypoplasia who presented abnormal fetal movements. Case presentation: A 27-year-old Japanese primigravida at 33 weeks of gestation was referred to our hospital. Ultrasonographic examination revealed clinical polyhydramnios. Micrognathia was evident on midsagittal and 3 D scan. The lung area was less than the mean -2.0 standard deviations for the gestational age. The infant had mandibular hypoplasia and glossoptosis. After emergency cesarean delivery for non-reasuring fetal status, required immediate tracheostomy and cardiopulmonary resuscitation with mechanical ventilatory support. However, the infant’s cardiopulmonary condition did not improve and she died 21 hours after birth. Conclusions: The findings of our ultrasound exam are suggestive of brain dysfunction. The observation of fetal behavior appears to be effective for the prediction of prognosis of cases with Micrognathia.

  • abnormal fetal movements Micrognathia and pulmonary hypoplasia a case report abnormal fetal movements
    BMC Pregnancy and Childbirth, 2010
    Co-Authors: Seiichi Morokuma, Ai Anami, Kiyomi Tsukimori, Kotaro Fukushima, Norio Wake
    Abstract:

    Background Micrognathia is a facial malformation characterized by mandibular hypoplasia and a small, receding chin that fails to maintain the tongue in a forward position. We previously reported a system of prenatal screening that we developed to identify fetuses with compromised central nervous system function by observing fetal behavior. In this paper we report the case of a preterm infant with Micrognathia and pulmonary hypoplasia who presented abnormal fetal movements.