The Experts below are selected from a list of 147 Experts worldwide ranked by ideXlab platform
Bernard Lambermont - One of the best experts on this subject based on the ideXlab platform.
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Effects of veno-venous extracorporeal CO2 removal on pulmonary hypertension in an ARDS model
European Respiratory Journal, 2015Co-Authors: Philippe Morimont, Julien Guiot, Thomas Desaive, Jean-olivier Defraigne, Bernard LambermontAbstract:Background: Protective ventilation (PV) with low tidal volumes is recommended in acute respiratory distress syndrome (ARDS). However, hypercapnic acidosis resulting from PV enhances pulmonary hypertension. Aim: We investigated if extracorporeal veno-venous CO 2 removal therapy could have beneficial effects on pulmonary circulation. Methods: This study was performed on an experimental model of ARDS obtained in 8 anaesthetized pigs connected to a volume-cycled ventilator. A Micromanometer-tipped catheter was inserted into the main pulmonary artery and an admittance Micromanometer-tipped catheter was inserted into the right ventricle. ARDS was obtained by repeated bronchoalveolar lavage. PV was then achieved and the pigs were connected to a pump-driven extracorporeal membrane oxygenator (PALP, Maquet, Germany) in order to achieve CO 2 removal. Results: ARDS induced severe hypercapnic acidosis. Systolic pulmonary artery pressure significantly increased from 29.6±1.8 to 43.9±2.0 mm Hg (p
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Veno-venous extracorporeal CO2 removal improves pulmonary hemodynamics in a porcine ARDS model
Acta Anaesthesiologica Scandinavica, 2015Co-Authors: Philippe Morimont, Julien Guiot, Thomas Desaive, Jean-olivier Defraigne, Vincent Tchana-sato, Nathalie Janssen, A Cagnina, Dominique Hella, Francine Blaffart, Bernard LambermontAbstract:Background Protective lung ventilation is recommended in patients with acute respiratory distress syndrome (ARDS) to minimize additional injuries to the lung. However, hypercapnic acidosis resulting from ventilation at lower tidal volume enhances pulmonary hypertension and might induce right ventricular (RV) failure. We investigated if extracorporeal veno-venous CO2 removal therapy could have beneficial effects on pulmonary circulation and RV function. Methods This study was performed on an experimental model of ARDS obtained in eight anaesthetized pigs connected to a volume-cycled ventilator. A Micromanometer-tipped catheter was inserted into the main pulmonary artery and an admittance Micromanometer-tipped catheter was inserted into the right ventricle. RV–arterial coupling was derived from RV pressure-volume loops. ARDS was obtained by repeated bronchoalveolar lavage. Protective ventilation was then achieved, and the pigs were connected to a pump-driven extracorporeal membrane oxygenator (PALP, Maquet, Germany) in order to achieve CO2 removal. Results ARDS induced severe hypercapnic acidosis. Systolic pulmonary artery pressure significantly increased from 29.6 ± 1.8 to 43.9 ± 2.0 mmHg (P
Steven L. Garverick - One of the best experts on this subject based on the ideXlab platform.
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Low-Power Wireless Micromanometer System for Acute and Chronic Bladder-Pressure Monitoring
IEEE Transactions on Biomedical Engineering, 2011Co-Authors: Steve Majerus, Paul C. Fletter, Margot S. Damaser, Steven L. GarverickAbstract:This letter describes the design, fabrication, and testing of a wireless bladder-pressure-sensing system for chronic, point-of-care applications, such as urodynamics or closed-loop neuromodulation. The system consists of a miniature implantable device and an external RF receiver and wireless battery charger. The implant is small enough to be cystoscopically implanted within the bladder wall, where it is securely held and shielded from the urine stream. The implant consists of a custom application-specific integrated circuit (ASIC), a pressure transducer, a rechargeable battery, and wireless telemetry and recharging antennas. The ASIC includes instrumentation, wireless transmission, and power-management circuitry, and on an average draws less than 9 μA from the 3.6-V battery. The battery charge can be wirelessly replenished with daily 6-h recharge periods that can occur during the periods of sleep. Acute in vivo evaluation of the pressure-sensing system in canine models has demonstrated that the system can accurately capture lumen pressure from a submucosal implant location.
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Wireless Micromanometer system for chronic bladder pressure monitoring
2009 Sixth International Conference on Networked Sensing Systems (INSS), 2009Co-Authors: Paul C. Fletter, Steve Majerus, Peng Cong, Margot S. Damaser, Wen H. Ko, Darrin J. Young, Steven L. GarverickAbstract:This paper describes a wireless system to monitor urinary bladder pressure comprising an implantable device with an external receiver and wireless battery charger. The device is intended to be implanted within the bladder wall, sealed behind the urothelial lining. This location is protected from the urine stream, thus avoiding mineral encrustation and stone formation, and is suitable to measure intravesical pressure in chronic applications. The implant is dimensionally designed to gain access to the bladder using conventional urological tools, e.g. a cystoscope. The active circuit implant features a custom application-specific integrated circuit (ASIC), rechargeable battery and wireless telemetry. Inductive charging, novel power management schemes and innovative packaging allow this device to be inserted through the urethra, implanted within the bladder wall, and operate for a lifetime of up to 10 years.
Albert De Roos - One of the best experts on this subject based on the ideXlab platform.
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cardiovascular mr imaging pressure gating using the arterial pressure signal from a conventional ferromagnetic Micromanometer tip catheter
Magnetic Resonance Imaging, 1994Co-Authors: Peter M T Pattynama, Enno T Van Der Velde, Paul Steendijk, Hildo J Lamb, Jan Baan, Albert De RoosAbstract:Abstract We used the arterial pressure wave as a reliable trigger to synchronize MR imaging to the cardiac cycle. Pressure readings and MR images remained undistorted using a conventional ferromagnetic Micromanometer-tip catheter. As a safe alternative to triggering to ventricular pressure, this approach allows varying the time relation between the trigger and the cardiac cycle while maintaining the advantages of pressure-gating.
Gerald M Pohost - One of the best experts on this subject based on the ideXlab platform.
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development of a Micromanometer tip catheter to record high fidelity pressures during cine gated nmr without significant image distortion
Magnetic Resonance in Medicine, 1991Co-Authors: Louis J Dellitalia, Bruce Carter, Huntly Millar, Gerald M PohostAbstract:We report a new Micromanometer-tip catheter to record high-fidelity pressures during cine-gated gradient echo NMR imaging in an intact animal model. Of the various metals and alloys tested for use in its construction, brass produced the smallest NMR artifact with minimal magnification. With the use of this new catheter design, there was little signal loss and no distortion of endocardial borders during imaging. © 1991 Academic Press, Inc.
Philippe Morimont - One of the best experts on this subject based on the ideXlab platform.
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Effects of veno-venous extracorporeal CO2 removal on pulmonary hypertension in an ARDS model
European Respiratory Journal, 2015Co-Authors: Philippe Morimont, Julien Guiot, Thomas Desaive, Jean-olivier Defraigne, Bernard LambermontAbstract:Background: Protective ventilation (PV) with low tidal volumes is recommended in acute respiratory distress syndrome (ARDS). However, hypercapnic acidosis resulting from PV enhances pulmonary hypertension. Aim: We investigated if extracorporeal veno-venous CO 2 removal therapy could have beneficial effects on pulmonary circulation. Methods: This study was performed on an experimental model of ARDS obtained in 8 anaesthetized pigs connected to a volume-cycled ventilator. A Micromanometer-tipped catheter was inserted into the main pulmonary artery and an admittance Micromanometer-tipped catheter was inserted into the right ventricle. ARDS was obtained by repeated bronchoalveolar lavage. PV was then achieved and the pigs were connected to a pump-driven extracorporeal membrane oxygenator (PALP, Maquet, Germany) in order to achieve CO 2 removal. Results: ARDS induced severe hypercapnic acidosis. Systolic pulmonary artery pressure significantly increased from 29.6±1.8 to 43.9±2.0 mm Hg (p
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Veno-venous extracorporeal CO2 removal improves pulmonary hemodynamics in a porcine ARDS model
Acta Anaesthesiologica Scandinavica, 2015Co-Authors: Philippe Morimont, Julien Guiot, Thomas Desaive, Jean-olivier Defraigne, Vincent Tchana-sato, Nathalie Janssen, A Cagnina, Dominique Hella, Francine Blaffart, Bernard LambermontAbstract:Background Protective lung ventilation is recommended in patients with acute respiratory distress syndrome (ARDS) to minimize additional injuries to the lung. However, hypercapnic acidosis resulting from ventilation at lower tidal volume enhances pulmonary hypertension and might induce right ventricular (RV) failure. We investigated if extracorporeal veno-venous CO2 removal therapy could have beneficial effects on pulmonary circulation and RV function. Methods This study was performed on an experimental model of ARDS obtained in eight anaesthetized pigs connected to a volume-cycled ventilator. A Micromanometer-tipped catheter was inserted into the main pulmonary artery and an admittance Micromanometer-tipped catheter was inserted into the right ventricle. RV–arterial coupling was derived from RV pressure-volume loops. ARDS was obtained by repeated bronchoalveolar lavage. Protective ventilation was then achieved, and the pigs were connected to a pump-driven extracorporeal membrane oxygenator (PALP, Maquet, Germany) in order to achieve CO2 removal. Results ARDS induced severe hypercapnic acidosis. Systolic pulmonary artery pressure significantly increased from 29.6 ± 1.8 to 43.9 ± 2.0 mmHg (P
