The Experts below are selected from a list of 315 Experts worldwide ranked by ideXlab platform

Maria Francisca Colellasantos - One of the best experts on this subject based on the ideXlab platform.

  • otoacoustic emissions in children with long term Middle Ear Disease
    Life, 2020
    Co-Authors: Milaine Dominici Sanfins, Caroline Donadon, Luisa Frata Bertazolli, Piotr H Skarzynski, Magdalena B Skarzynska, Maria Francisca Colellasantos
    Abstract:

    Introduction Otoacoustic emissions (OAEs) evaluate the functional status of the cochlea. Repeated otitis media (OM) can cause changes in the peripheral structures of the auditory system, and, in this way, Middle Ear infection may irreversibly damage the Middle Ear, or even the cochlea. Objectives To analyze the results of transiently evoked otoacoustic emissions (TEOAEs) and distortion product otoacoustic emissions (DPOAEs) in individuals with a history of OM. Method Participants with 8 to 16 yEars of schooling were split into two groups: a control group (CG) of 50 subjects who had no history of otological Disease and an experimental group (EG) of 50 subjects who had a history of recurrent otitis in childhood and had consequently undergone myringotomy to insert bilateral ventilation tubes. All children underwent basic audiological assessment (tonal audiometry, speech audiometry, and immittance testing) and otoacoustic emission testing (TEOAEs and DPOAEs). Results There were no significant differences between the groups when audiometrically tested via air and bone conduction. OAEs were found in all CG subjects. For the EG, there were no TEOAE responses in 17 Ears and no DPOAEs in nine Ears; response amplitudes were lower at all frequencies. The emission level and the signal-to-noise ratio were statistically different between the two groups, and OAEs in the EG were statistically smaller compared to the GC. Conclusion In the EG, responses were more likely to be absent and were of statistically smaller amplitude compared to the CG. A history of repeated OM apparently interferes with the generation and transmission of TEOAEs and DPOAEs.

  • long term effect of Middle Ear Disease on temporal processing and p300 in two different populations of children
    PLOS ONE, 2020
    Co-Authors: Leticia Reis Borges, Dani Tomlin, Milaine Dominici Sanfins, Caroline Donadon, Maria Francisca Colellasantos
    Abstract:

    BACKGROUND/OBJECTIVE: The effects of otitis media on the function of the central auditory nervous system in different populations is unknown. Understanding how the history of otitis media affects children from different nations will guide health professionals worldwide on the importance of adequate auditory stimulus in childhood. For this reason, the aim of the present study was to investigate the long-term auditory effects of Middle Ear Disease on temporal processing and P300 in two different populations of children: Australian and Brazilian. METHODS: Temporal processing tests (Frequency Pattern Tests-FPT and Gaps in noise-GIN) and P300 were measured in 68 Brazilian and Australian children, aged between 8 to 14 yEars. The Brazilian otitis media group (BrOM) and Australian otitis media group (AusOM) consisted of 20 children each who had a documented history of otitis media. Control groups of 14 children (BrControl and AusControl) were also recruited from each country, all with no documented history of otitis media. RESULTS: The BrOM group showed significantly poorer performance (p<0.001) for FPT and the GIN compared to BrControl. The P300 response showed significantly longer mean latencies (p = 0.02) compared to BrControls. The AusOM group also showed significant delayed latency of P300 (p = 0.04) compared to the AusControl. The FPT showed significantly poorer performance (p = 0.04) compared to AusControls. The two otitis media groups showed no significant differences between each other on P300. Significant differences were seen however in temporal processing tests performance between the two cohorts for the otitis media groups. The BrOM group had significantly poorer responses (p<0.001) for FPT and GIN compared to the AusOM group. CONCLUSIONS: These findings support that although differences exist between BrOM and AusOM groups, otitis media can be demonstrated to affect the underlying mechanisms of the P300 measures and behavioral auditory responses in two different populations of children.

Derek G Cook - One of the best experts on this subject based on the ideXlab platform.

  • parental smoking and the risk of Middle Ear Disease in children a systematic review and meta analysis
    JAMA Pediatrics, 2012
    Co-Authors: Laura Jones, John Britton, Amal Hassanien, Derek G Cook, Jo Leonardibee
    Abstract:

    Objective: A systematic review and meta-analysis of studies of the association between secondhand tobacco smoke (SHTS) and Middle Ear Disease (MED) in children.

  • parental smoking and the risk of Middle Ear Disease in children a systematic review and meta analysis
    JAMA Pediatrics, 2012
    Co-Authors: Laura Jones, John Britton, Amal Hassanien, Derek G Cook, Jo Leonardibee
    Abstract:

    Objective: A systematic review and meta-analysis of studies of the association between secondhand tobacco smoke (SHTS) and Middle Ear Disease (MED) in children.

  • health effects of passive smoking 4 parental smoking Middle Ear Disease and adenotonsillectomy in children
    Thorax, 1998
    Co-Authors: David P Strachan, Derek G Cook
    Abstract:

    BACKGROUND: A systematic quantitative review was conducted of evidence relating parental smoking to acute otitis media, recurrent otitis media, Middle Ear effusion, and adenoidectomy and/or tonsillectomy. METHODS: Forty five relevant publications were identified after consideration of 692 articles selected by electronic sEarch of the Embase and Medline databases using keywords relevant to passive smoking in children. The sEarch was completed in April 1997 and identified 13 studies of acute otitis media, nine of recurrent otitis media, five of Middle Ear effusion, nine of glue Ear surgery, and four of adenotonsillectomy. A quantitative meta-analysis was possible for all outcomes except acute otitis media, using random effects modelling where appropriate to pool odds ratios from each study. RESULTS: Evidence for Middle Ear Disease is remarkably consistent, with pooled odds ratios if either parent smoked of 1.48 (95% CI 1.08 to 2.04) for recurrent otitis media, 1.38 (1.23 to 1.55) for Middle Ear effusion, and 1.21 (0.95 to 1.53) for outpatient or inpatient referral for glue Ear. Odds ratios for acute otitis media are in the range 1.0 to 1.6. No single study simultaneously addresses selection bias, information bias and confounding, but where these have been investigated or excluded in the design or analysis, the associations with parental smoking persist virtually unchanged. Large French and British studies are inconsistent with regard to the association of parental smoking and tonsillectomy. CONCLUSIONS: There is likely to be a causal relationship between parental smoking and both acute and chronic Middle Ear Disease in children.

Paul Little - One of the best experts on this subject based on the ideXlab platform.

  • consultations for Middle Ear Disease antibiotic prescribing and risk factors for reattendance a case linked cohort study
    British Journal of General Practice, 2006
    Co-Authors: Ian Williamson, Sarah Benge, Mark Mullee, Paul Little
    Abstract:

    Background Otitis media is the most common reason for children to receive antibiotics, but there is no evidence about the effect of prescribing on reattendance. Aim To evaluate the changing workload of Middle Ear Disease in general practice, and the impact on surgery reattendance of prescribing antibiotics at first attendance. Design of study A case-linked cohort analysis for antibiotic prescribing versus no prescribing at first consultation event. Setting Two hundred and ninety-one practices spread throughout the UK recording for the General Practice ResEarch Database (GPRD) and incorporating individual patient data records for 2 265 574 patients. Method All Middle Ear Disease coded events that can be classed within acute otitis media (AOM) or glue Ear sub-categories (and excluding chronic suppurative otitis media) were selected for analysis when the first event was from 1991–2001. The effect of antibiotic prescription on the risk of reattendance using Cox proportional hazards regression was analysed. Results Total consultations for AOM have fallen markedly over this decade, and glue Ear consultations have risen but by a much smaller extent (26 000 decrease versus 4000 increase in consultations per yEar), which makes re-labelling an unlikely explanation of the fall in AOM consultations. In the 2–10 yEars age range, consultations for AOM fell from 105.3 to 34.7 per 1000 per yEar, with glue Ear consultations unaltered (15.2 to 16.7 per 1000 per yEar). Antibiotic prescribing for AOM has stayed remarkably constant (80–84% of consultations), but antibiotic prescribing for glue Ear has risen sharply (13 to 62%). Prescribing antibiotics increased the risk of reattendance for AOM (hazard ratio [HR] = 1.09, 95% confidence interval [CI] = 1.07 to 1.10) and has reduced the risk of reattendance for glue Ear (HR = 0.92, 95% CI = 0.88 to 0.96). Conclusion Prescribing antibiotics for AOM probably increased reattendance, but the opposite effect has been noted for glue Ear, which suggests a treatment effect of antibiotics in glue Ear. Further resEarch is needed to clarify whether this possible benefit is worth the known harms, and if so in which subgroups of children.

  • consultations for Middle Ear Disease antibiotic prescribing and risk factors for reattendance
    2006
    Co-Authors: Ian Williamson, Sarah Benge, Mark Mullee, Paul Little
    Abstract:

    Background Otitis media is the most common reason for children to receive antibiotics, but there is no evidence about the effect of prescribing on reattendance. Aim To evaluate the changing workload of Middle Ear Disease in general practice, and the impact on surgery reattendance of prescribing antibiotics at first attendance. Design of study A case-linked cohort analysis for antibiotic prescribing versus no prescribing at first consultation event.

Jo Leonardibee - One of the best experts on this subject based on the ideXlab platform.

Ian Williamson - One of the best experts on this subject based on the ideXlab platform.

  • consultations for Middle Ear Disease antibiotic prescribing and risk factors for reattendance a case linked cohort study
    British Journal of General Practice, 2006
    Co-Authors: Ian Williamson, Sarah Benge, Mark Mullee, Paul Little
    Abstract:

    Background Otitis media is the most common reason for children to receive antibiotics, but there is no evidence about the effect of prescribing on reattendance. Aim To evaluate the changing workload of Middle Ear Disease in general practice, and the impact on surgery reattendance of prescribing antibiotics at first attendance. Design of study A case-linked cohort analysis for antibiotic prescribing versus no prescribing at first consultation event. Setting Two hundred and ninety-one practices spread throughout the UK recording for the General Practice ResEarch Database (GPRD) and incorporating individual patient data records for 2 265 574 patients. Method All Middle Ear Disease coded events that can be classed within acute otitis media (AOM) or glue Ear sub-categories (and excluding chronic suppurative otitis media) were selected for analysis when the first event was from 1991–2001. The effect of antibiotic prescription on the risk of reattendance using Cox proportional hazards regression was analysed. Results Total consultations for AOM have fallen markedly over this decade, and glue Ear consultations have risen but by a much smaller extent (26 000 decrease versus 4000 increase in consultations per yEar), which makes re-labelling an unlikely explanation of the fall in AOM consultations. In the 2–10 yEars age range, consultations for AOM fell from 105.3 to 34.7 per 1000 per yEar, with glue Ear consultations unaltered (15.2 to 16.7 per 1000 per yEar). Antibiotic prescribing for AOM has stayed remarkably constant (80–84% of consultations), but antibiotic prescribing for glue Ear has risen sharply (13 to 62%). Prescribing antibiotics increased the risk of reattendance for AOM (hazard ratio [HR] = 1.09, 95% confidence interval [CI] = 1.07 to 1.10) and has reduced the risk of reattendance for glue Ear (HR = 0.92, 95% CI = 0.88 to 0.96). Conclusion Prescribing antibiotics for AOM probably increased reattendance, but the opposite effect has been noted for glue Ear, which suggests a treatment effect of antibiotics in glue Ear. Further resEarch is needed to clarify whether this possible benefit is worth the known harms, and if so in which subgroups of children.

  • consultations for Middle Ear Disease antibiotic prescribing and risk factors for reattendance
    2006
    Co-Authors: Ian Williamson, Sarah Benge, Mark Mullee, Paul Little
    Abstract:

    Background Otitis media is the most common reason for children to receive antibiotics, but there is no evidence about the effect of prescribing on reattendance. Aim To evaluate the changing workload of Middle Ear Disease in general practice, and the impact on surgery reattendance of prescribing antibiotics at first attendance. Design of study A case-linked cohort analysis for antibiotic prescribing versus no prescribing at first consultation event.