The Experts below are selected from a list of 1770 Experts worldwide ranked by ideXlab platform

Paolo De Coppi - One of the best experts on this subject based on the ideXlab platform.

  • clot dissolution a novel treatment of Midgut volvulus
    Pediatrics, 2012
    Co-Authors: Edward M. Kiely, Agostino Pierro, Christine Pierce, Kate Cross, Paolo De Coppi
    Abstract:

    Midgut volvulus due to malrotation may result in loss of the small bowel. Until now, after derotation of the volvulus, pediatric surgeons do not deal with the mesenteric thrombosis, which causes continuing ischemia of the intestine. On occasion, a "second look" laparotomy is performed in the hope that some improvement in blood supply to the intestine has occurred. We describe a new combined treatment to restore intestinal perfusion based on digital massage of the superior mesenteric vessels after derotation and systemic infusion of tissue-type plasminogen activator. This new therapy has been successful in 2 neonates with severe intestinal ischemia due to volvulus.

  • Clot dissolution: a novel treatment of Midgut volvulus.
    PEDIATRICS, 2012
    Co-Authors: Edward M. Kiely, Agostino Pierro, Christine Pierce, Kate Cross, Paolo De Coppi
    Abstract:

    Midgut volvulus due to malrotation may result in loss of the small bowel. Until now, after derotation of the volvulus, pediatric surgeons do not deal with the mesenteric thrombosis, which causes continuing ischemia of the intestine. On occasion, a “second look” laparotomy is performed in the hope that some improvement in blood supply to the intestine has occurred. We describe a new combined treatment to restore intestinal perfusion based on digital massage of the superior mesenteric vessels after derotation and systemic infusion of tissue-type plasminogen activator. This new therapy has been successful in 2 neonates with severe intestinal ischemia due to volvulus. * Abbreviations: tPA — : tissue-type plasminogen activator

Olivier Prodhomme - One of the best experts on this subject based on the ideXlab platform.

  • Prenatal diagnosis of antenatal Midgut volvulus: Specific ultrasound features
    Prenatal Diagnosis, 2019
    Co-Authors: Caroline Bartholmot, Jean‐michel Faure, Frédéric Grosjean, Alain Couture, Dominique Forgues, Florent Fuchs, Olivier Prodhomme
    Abstract:

    OBJECTIVE: To assess specific, direct, and indirect prenatal ultrasound features in cases of fetal Midgut volvulus. METHODS: Retrospective case series of neonatal volvulus, based on postnatal and prenatal imaging findings that occurred from 2006-2017. Prenatal and postnatal signs including the specific "whirlpool sign" were computed. Postnatal volvulus was confirmed by pathology examination after surgery or neonatal autopsy. RESULTS: Thirteen cases of Midgut volvulus were identified. Though not a specific sign, a decrease in active fetal movements was reported in eight patients (61.5%). The prenatal whirlpool sign was directly seen in 10 cases, while an indirect but suggestive sign, a fluid-filled level within the dilated loops, was present in five cases. No intestinal malrotation was observed. Pregnancy outcomes were two terminations of pregnancy, both associated with cystic fibrosis, one early neonatal death, three prenatal spontaneous regressions, and seven favorable outcomes after neonatal surgery with resection of Midgut atresia. CONCLUSIONS: Identification of the whirlpool sign or of a fluid-filled level within the dilated loops improves the accuracy of ultrasound findings for suspected volvulus. In the absence of total volvulus (in cases of intestinal malrotation) or association with cystic fibrosis, the prognosis appears good.

Edward M. Kiely - One of the best experts on this subject based on the ideXlab platform.

  • clot dissolution a novel treatment of Midgut volvulus
    Pediatrics, 2012
    Co-Authors: Edward M. Kiely, Agostino Pierro, Christine Pierce, Kate Cross, Paolo De Coppi
    Abstract:

    Midgut volvulus due to malrotation may result in loss of the small bowel. Until now, after derotation of the volvulus, pediatric surgeons do not deal with the mesenteric thrombosis, which causes continuing ischemia of the intestine. On occasion, a "second look" laparotomy is performed in the hope that some improvement in blood supply to the intestine has occurred. We describe a new combined treatment to restore intestinal perfusion based on digital massage of the superior mesenteric vessels after derotation and systemic infusion of tissue-type plasminogen activator. This new therapy has been successful in 2 neonates with severe intestinal ischemia due to volvulus.

  • Clot dissolution: a novel treatment of Midgut volvulus.
    PEDIATRICS, 2012
    Co-Authors: Edward M. Kiely, Agostino Pierro, Christine Pierce, Kate Cross, Paolo De Coppi
    Abstract:

    Midgut volvulus due to malrotation may result in loss of the small bowel. Until now, after derotation of the volvulus, pediatric surgeons do not deal with the mesenteric thrombosis, which causes continuing ischemia of the intestine. On occasion, a “second look” laparotomy is performed in the hope that some improvement in blood supply to the intestine has occurred. We describe a new combined treatment to restore intestinal perfusion based on digital massage of the superior mesenteric vessels after derotation and systemic infusion of tissue-type plasminogen activator. This new therapy has been successful in 2 neonates with severe intestinal ischemia due to volvulus. * Abbreviations: tPA — : tissue-type plasminogen activator

Caroline Bartholmot - One of the best experts on this subject based on the ideXlab platform.

  • Prenatal diagnosis of antenatal Midgut volvulus: Specific ultrasound features
    Prenatal Diagnosis, 2019
    Co-Authors: Caroline Bartholmot, Jean‐michel Faure, Frédéric Grosjean, Alain Couture, Dominique Forgues, Florent Fuchs, Olivier Prodhomme
    Abstract:

    OBJECTIVE: To assess specific, direct, and indirect prenatal ultrasound features in cases of fetal Midgut volvulus. METHODS: Retrospective case series of neonatal volvulus, based on postnatal and prenatal imaging findings that occurred from 2006-2017. Prenatal and postnatal signs including the specific "whirlpool sign" were computed. Postnatal volvulus was confirmed by pathology examination after surgery or neonatal autopsy. RESULTS: Thirteen cases of Midgut volvulus were identified. Though not a specific sign, a decrease in active fetal movements was reported in eight patients (61.5%). The prenatal whirlpool sign was directly seen in 10 cases, while an indirect but suggestive sign, a fluid-filled level within the dilated loops, was present in five cases. No intestinal malrotation was observed. Pregnancy outcomes were two terminations of pregnancy, both associated with cystic fibrosis, one early neonatal death, three prenatal spontaneous regressions, and seven favorable outcomes after neonatal surgery with resection of Midgut atresia. CONCLUSIONS: Identification of the whirlpool sign or of a fluid-filled level within the dilated loops improves the accuracy of ultrasound findings for suspected volvulus. In the absence of total volvulus (in cases of intestinal malrotation) or association with cystic fibrosis, the prognosis appears good.

Paul Leyman - One of the best experts on this subject based on the ideXlab platform.