The Experts below are selected from a list of 15 Experts worldwide ranked by ideXlab platform

E Regar - One of the best experts on this subject based on the ideXlab platform.

  • randomized study to assess the effect of thrombus aspiration on Flow Area in patients with st elevation myocardial infarction an optical frequency domain imaging study trofi trial
    European Heart Journal, 2013
    Co-Authors: Yoshinobu Onuma, Leif Thuesen, Robert Jan Van Geuns, Martin Van Der Ent, Steffen Desch, Jean Fajadet, Evald Hoj Christiansen, Peter Smits, Niels Ramsing Holm, E Regar
    Abstract:

    Aims Primary percutaneous coronary intervention (PPCI) with thrombectomy (TB) seems to reduce the thrombus burden, resulting in a larger Flow Area as measured with optical frequency domain imaging (OFDI). Methods and results In a multi-centre study, 141 patients with ST elevation myocardial infarction <12 h from onset were randomized to either PPCI with TB using an Eliminate catheter (TB: n = 71) or without TB (non-TB: n = 70), having operators blinded for the OFDI results. The primary endpoint was Minimum Flow Area (MinFA) post-procedure assessed by OFDI, defined as: [stent Area + incomplete stent apposition (ISA) Area] − (intraluminal defect + tissue prolapse Area). Sample size was based on the expected difference of 0.72 mm2 in MinFA. Baseline demographics, pre-procedural quantitative coronary angiography (QCA), and procedural characteristics were well matched between the two groups. On OFDI, the stent Area (TB: 7.62 ± 2.23 mm2, non-TB: 7.05 ± 2.12 mm2, P = 0.14) and MinFA (TB: 7.08 ± 2.14 mm2 vs. non-TB: 6.51 ± 1.99 mm2, Δ0.57 mm2, P = 0.12) were not different. In addition, the amount of protrusion, intraluminal defect, and ISA Area were similar in the both groups. Conclusion PPCI with TB was associated with a similar Flow Area as well as stent Area to PPCI without TB.

Yoshinobu Onuma - One of the best experts on this subject based on the ideXlab platform.

  • randomized study to assess the effect of thrombus aspiration on Flow Area in patients with st elevation myocardial infarction an optical frequency domain imaging study trofi trial
    European Heart Journal, 2013
    Co-Authors: Yoshinobu Onuma, Leif Thuesen, Robert Jan Van Geuns, Martin Van Der Ent, Steffen Desch, Jean Fajadet, Evald Hoj Christiansen, Peter Smits, Niels Ramsing Holm, E Regar
    Abstract:

    Aims Primary percutaneous coronary intervention (PPCI) with thrombectomy (TB) seems to reduce the thrombus burden, resulting in a larger Flow Area as measured with optical frequency domain imaging (OFDI). Methods and results In a multi-centre study, 141 patients with ST elevation myocardial infarction <12 h from onset were randomized to either PPCI with TB using an Eliminate catheter (TB: n = 71) or without TB (non-TB: n = 70), having operators blinded for the OFDI results. The primary endpoint was Minimum Flow Area (MinFA) post-procedure assessed by OFDI, defined as: [stent Area + incomplete stent apposition (ISA) Area] − (intraluminal defect + tissue prolapse Area). Sample size was based on the expected difference of 0.72 mm2 in MinFA. Baseline demographics, pre-procedural quantitative coronary angiography (QCA), and procedural characteristics were well matched between the two groups. On OFDI, the stent Area (TB: 7.62 ± 2.23 mm2, non-TB: 7.05 ± 2.12 mm2, P = 0.14) and MinFA (TB: 7.08 ± 2.14 mm2 vs. non-TB: 6.51 ± 1.99 mm2, Δ0.57 mm2, P = 0.12) were not different. In addition, the amount of protrusion, intraluminal defect, and ISA Area were similar in the both groups. Conclusion PPCI with TB was associated with a similar Flow Area as well as stent Area to PPCI without TB.

Niels Ramsing Holm - One of the best experts on this subject based on the ideXlab platform.

  • randomized study to assess the effect of thrombus aspiration on Flow Area in patients with st elevation myocardial infarction an optical frequency domain imaging study trofi trial
    European Heart Journal, 2013
    Co-Authors: Yoshinobu Onuma, Leif Thuesen, Robert Jan Van Geuns, Martin Van Der Ent, Steffen Desch, Jean Fajadet, Evald Hoj Christiansen, Peter Smits, Niels Ramsing Holm, E Regar
    Abstract:

    Aims Primary percutaneous coronary intervention (PPCI) with thrombectomy (TB) seems to reduce the thrombus burden, resulting in a larger Flow Area as measured with optical frequency domain imaging (OFDI). Methods and results In a multi-centre study, 141 patients with ST elevation myocardial infarction <12 h from onset were randomized to either PPCI with TB using an Eliminate catheter (TB: n = 71) or without TB (non-TB: n = 70), having operators blinded for the OFDI results. The primary endpoint was Minimum Flow Area (MinFA) post-procedure assessed by OFDI, defined as: [stent Area + incomplete stent apposition (ISA) Area] − (intraluminal defect + tissue prolapse Area). Sample size was based on the expected difference of 0.72 mm2 in MinFA. Baseline demographics, pre-procedural quantitative coronary angiography (QCA), and procedural characteristics were well matched between the two groups. On OFDI, the stent Area (TB: 7.62 ± 2.23 mm2, non-TB: 7.05 ± 2.12 mm2, P = 0.14) and MinFA (TB: 7.08 ± 2.14 mm2 vs. non-TB: 6.51 ± 1.99 mm2, Δ0.57 mm2, P = 0.12) were not different. In addition, the amount of protrusion, intraluminal defect, and ISA Area were similar in the both groups. Conclusion PPCI with TB was associated with a similar Flow Area as well as stent Area to PPCI without TB.

Leif Thuesen - One of the best experts on this subject based on the ideXlab platform.

  • randomized study to assess the effect of thrombus aspiration on Flow Area in patients with st elevation myocardial infarction an optical frequency domain imaging study trofi trial
    European Heart Journal, 2013
    Co-Authors: Yoshinobu Onuma, Leif Thuesen, Robert Jan Van Geuns, Martin Van Der Ent, Steffen Desch, Jean Fajadet, Evald Hoj Christiansen, Peter Smits, Niels Ramsing Holm, E Regar
    Abstract:

    Aims Primary percutaneous coronary intervention (PPCI) with thrombectomy (TB) seems to reduce the thrombus burden, resulting in a larger Flow Area as measured with optical frequency domain imaging (OFDI). Methods and results In a multi-centre study, 141 patients with ST elevation myocardial infarction <12 h from onset were randomized to either PPCI with TB using an Eliminate catheter (TB: n = 71) or without TB (non-TB: n = 70), having operators blinded for the OFDI results. The primary endpoint was Minimum Flow Area (MinFA) post-procedure assessed by OFDI, defined as: [stent Area + incomplete stent apposition (ISA) Area] − (intraluminal defect + tissue prolapse Area). Sample size was based on the expected difference of 0.72 mm2 in MinFA. Baseline demographics, pre-procedural quantitative coronary angiography (QCA), and procedural characteristics were well matched between the two groups. On OFDI, the stent Area (TB: 7.62 ± 2.23 mm2, non-TB: 7.05 ± 2.12 mm2, P = 0.14) and MinFA (TB: 7.08 ± 2.14 mm2 vs. non-TB: 6.51 ± 1.99 mm2, Δ0.57 mm2, P = 0.12) were not different. In addition, the amount of protrusion, intraluminal defect, and ISA Area were similar in the both groups. Conclusion PPCI with TB was associated with a similar Flow Area as well as stent Area to PPCI without TB.

Robert Jan Van Geuns - One of the best experts on this subject based on the ideXlab platform.

  • randomized study to assess the effect of thrombus aspiration on Flow Area in patients with st elevation myocardial infarction an optical frequency domain imaging study trofi trial
    European Heart Journal, 2013
    Co-Authors: Yoshinobu Onuma, Leif Thuesen, Robert Jan Van Geuns, Martin Van Der Ent, Steffen Desch, Jean Fajadet, Evald Hoj Christiansen, Peter Smits, Niels Ramsing Holm, E Regar
    Abstract:

    Aims Primary percutaneous coronary intervention (PPCI) with thrombectomy (TB) seems to reduce the thrombus burden, resulting in a larger Flow Area as measured with optical frequency domain imaging (OFDI). Methods and results In a multi-centre study, 141 patients with ST elevation myocardial infarction <12 h from onset were randomized to either PPCI with TB using an Eliminate catheter (TB: n = 71) or without TB (non-TB: n = 70), having operators blinded for the OFDI results. The primary endpoint was Minimum Flow Area (MinFA) post-procedure assessed by OFDI, defined as: [stent Area + incomplete stent apposition (ISA) Area] − (intraluminal defect + tissue prolapse Area). Sample size was based on the expected difference of 0.72 mm2 in MinFA. Baseline demographics, pre-procedural quantitative coronary angiography (QCA), and procedural characteristics were well matched between the two groups. On OFDI, the stent Area (TB: 7.62 ± 2.23 mm2, non-TB: 7.05 ± 2.12 mm2, P = 0.14) and MinFA (TB: 7.08 ± 2.14 mm2 vs. non-TB: 6.51 ± 1.99 mm2, Δ0.57 mm2, P = 0.12) were not different. In addition, the amount of protrusion, intraluminal defect, and ISA Area were similar in the both groups. Conclusion PPCI with TB was associated with a similar Flow Area as well as stent Area to PPCI without TB.