The Experts below are selected from a list of 294 Experts worldwide ranked by ideXlab platform
J. Roberts - One of the best experts on this subject based on the ideXlab platform.
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POSTERIOR SOFT TISSUE REPAIR IN TOTAL HIP ARTHROPLASTY: A SIMPLE AND CHEAP Suture PASSING TECHNIQUE
2018Co-Authors: C. Diffin, M. Chambers, L. Campton, J. RobertsAbstract:Posterior soft tissue repair is often performed in Total Hip Arthroplasty (THA). Many reports have shown the advantage of posterior soft tissue repair in reducing their prosthetic hip dislocation rates.We describe an easy and inexpensive way of passing Sutures through small drill holes in the Greater Trocanter to re-attach muscle, tendon and capsule in a posterior soft tissue repair.By using a reversed Monofilament Suture on a straight needle held in artery forceps and passing this in a retrograde direction through a drill hole, a Suture capturing device is produced.By capturing the long ends of Sutures tied in the short external rotators and the posterior capsule of the hip through 2 drill holes in the Greater Trochanter, a posterior soft tissue repair can be performed. We have used this technique successfully in over 100 consecutive THAs.We conclude that the use of a Monofilament Suture used in the manner describe is an excellent and inexpensive way to aid in a posterior soft tissue repair in THAs. This...
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POSTERIOR SOFT TISSUE REPAIR IN TOTAL HIP ARTHROPLASTY: A SIMPLE AND CHEAP Suture PASSING TECHNIQUE
Journal of Bone and Joint Surgery-british Volume, 2013Co-Authors: C. Diffin, M. Chambers, L. Campton, J. RobertsAbstract:Posterior soft tissue repair is often performed in Total Hip Arthroplasty (THA). Many reports have shown the advantage of posterior soft tissue repair in reducing their prosthetic hip dislocation rates. We describe an easy and inexpensive way of passing Sutures through small drill holes in the Greater Trocanter to re-attach muscle, tendon and capsule in a posterior soft tissue repair. By using a reversed Monofilament Suture on a straight needle held in artery forceps and passing this in a retrograde direction through a drill hole, a Suture capturing device is produced. By capturing the long ends of Sutures tied in the short external rotators and the posterior capsule of the hip through 2 drill holes in the Greater Trochanter, a posterior soft tissue repair can be performed. We have used this technique successfully in over 100 consecutive THAs. We conclude that the use of a Monofilament Suture used in the manner describe is an excellent and inexpensive way to aid in a posterior soft tissue repair in THAs. This is done without the cost of an additional dedicated Suture passing device. The Suture could also be used in the skin closure if desired.
Yazmin Faiza - One of the best experts on this subject based on the ideXlab platform.
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relationship between vaginal microbial dysbiosis inflammation and pregnancy outcomes in cervical cerclage
Science Translational Medicine, 2016Co-Authors: Lindsay M Kindinger, Fidan Israfilbayli, C Lees, David A Macintyre, Julian R Marchesi, Ann Smith, Julie A K Mcdonald, Vasso Terzidou, Joanna R Cook, Yazmin FaizaAbstract:Preterm birth, the leading cause of death in children under 5 years, may be caused by inflammation triggered by ascending vaginal infection. About 2 million cervical cerclages are performed annually to prevent preterm birth. The procedure is thought to provide structural support and maintain the endocervical mucus plug as a barrier to ascending infection. Two types of Suture material are used for cerclage: Monofilament or multifilament braided. Braided Sutures are most frequently used, although no evidence exists to favor them over Monofilament Sutures. We assessed birth outcomes in a retrospective cohort of 678 women receiving cervical cerclage in five UK university hospitals and showed that braided cerclage was associated with increased intrauterine death (15% versus 5%; P = 0.0001) and preterm birth (28% versus 17%; P = 0.0006) compared to Monofilament Suture. To understand the potential underlying mechanism, we performed a prospective, longitudinal study of the vaginal microbiome in women at risk of preterm birth because of short cervical length (≤25 mm) who received braided (n = 25) or Monofilament (n = 24) cerclage under comparable circumstances. Braided Suture induced a persistent shift toward vaginal microbiome dysbiosis characterized by reduced Lactobacillus spp. and enrichment of pathobionts. Vaginal dysbiosis was associated with inflammatory cytokine and interstitial collagenase excretion into cervicovaginal fluid and premature cervical remodeling. Monofilament Suture had comparatively minimal impact upon the vaginal microbiome and its interactions with the host. These data provide in vivo evidence that a dynamic shift of the human vaginal microbiome toward dysbiosis correlates with preterm birth.
Lindsay M Kindinger - One of the best experts on this subject based on the ideXlab platform.
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relationship between vaginal microbial dysbiosis inflammation and pregnancy outcomes in cervical cerclage
Science Translational Medicine, 2016Co-Authors: Lindsay M Kindinger, Fidan Israfilbayli, C Lees, David A Macintyre, Julian R Marchesi, Ann Smith, Julie A K Mcdonald, Vasso Terzidou, Joanna R Cook, Yazmin FaizaAbstract:Preterm birth, the leading cause of death in children under 5 years, may be caused by inflammation triggered by ascending vaginal infection. About 2 million cervical cerclages are performed annually to prevent preterm birth. The procedure is thought to provide structural support and maintain the endocervical mucus plug as a barrier to ascending infection. Two types of Suture material are used for cerclage: Monofilament or multifilament braided. Braided Sutures are most frequently used, although no evidence exists to favor them over Monofilament Sutures. We assessed birth outcomes in a retrospective cohort of 678 women receiving cervical cerclage in five UK university hospitals and showed that braided cerclage was associated with increased intrauterine death (15% versus 5%; P = 0.0001) and preterm birth (28% versus 17%; P = 0.0006) compared to Monofilament Suture. To understand the potential underlying mechanism, we performed a prospective, longitudinal study of the vaginal microbiome in women at risk of preterm birth because of short cervical length (≤25 mm) who received braided (n = 25) or Monofilament (n = 24) cerclage under comparable circumstances. Braided Suture induced a persistent shift toward vaginal microbiome dysbiosis characterized by reduced Lactobacillus spp. and enrichment of pathobionts. Vaginal dysbiosis was associated with inflammatory cytokine and interstitial collagenase excretion into cervicovaginal fluid and premature cervical remodeling. Monofilament Suture had comparatively minimal impact upon the vaginal microbiome and its interactions with the host. These data provide in vivo evidence that a dynamic shift of the human vaginal microbiome toward dysbiosis correlates with preterm birth.
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Relationship between vaginal microbial dysbiosis, inflammation and pregnancy outcomes in cervical cerclage
'American Association for the Advancement of Science (AAAS)', 2016Co-Authors: Lindsay M Kindinger, Da Macintyre, Ys Lee, Smith A, Ja Mcdonald, Lees C, Israfil-bayli FAbstract:Preterm birth, the leading cause of death in children under five, may be caused by inflammation triggered by ascending vaginal infection. About two million cervical cerclages are performed annually to prevent preterm birth. The procedure is thought to provide structural support and maintain the endocervical mucus plug as a barrier to ascending infection. Two types of Suture material are used for cerclage: Monofilament or multifilament braided. Braided Sutures are most frequently used, though no evidence exists to favor them over Monofilament Sutures. In this study we assessed birth outcomes in a retrospective cohort of 678 women receiving cervical cerclage in 5 UK university hospitals and showed that braided cerclage was associated with increased intrauterine death (15% v 5%, P = 0.0001) and preterm birth (28% v 17%, P = 0.0006) compared to Monofilament Suture. To understand the potential underlying mechanism, we performed a prospective, longitudinal study of the vaginal microbiome in women at risk of preterm birth because of short cervical length (≤25 mm) who received braided (n=25) or Monofilament (n=24) cerclage under otherwise comparable circumstances. Braided Suture induced a persistent shift towards vaginal microbiome dysbiosis characterized by reduced Lactobacillus spp. and enrichment of pathobionts. Vaginal dysbiosis was associated with inflammatory cytokine and interstitial collagenase excretion into cervicovaginal fluid and premature cervical remodeling. Monofilament Suture had comparatively minimal impact upon the vaginal microbiome and its interactions with the host. These data provide in vivo evidence that a dynamic shift of the human vaginal microbiome toward dysbiosis correlates with preterm birth
David C. Markel - One of the best experts on this subject based on the ideXlab platform.
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Decreased Bacterial Adherence, Biofilm Formation, and Tissue Reactivity of Barbed Monofilament Suture in an In Vivo Contaminated Wound Model.
The Journal of arthroplasty, 2016Co-Authors: Michael R. Morris, Christopher Bergum, Nancy Jackson, David C. MarkelAbstract:Abstract Background Monofilament and barbed Monofilament Sutures have been shown in in vitro models to have less bacterial adherence than braided Suture. This study evaluates bacterial adherence to Suture materials and tissue reactivity with an in vivo contaminated wound mouse model. Methods Staphylococcus aureus was used to create an in vivo contaminated wound model at 2 amounts (10 6 colony-forming units [CFU] and 10 8 CFU) using a mouse air pouch. Three types of commonly used absorbable Suture were evaluated: braided, Monofilament, and barbed Monofilament. Bacterial Suture adherence was evaluated with Suture culture, a photon-capturing camera system, and scanning electron microscopy. Tissue reactivity was assessed through histology and protein expression. Results The braided Suture group with the high amount of S aureus exhibited frank purulence and air pouch hypertrophy in all 8 mice. A significant difference was found between Suture groups inoculated with 10 8 CFU ( P P P P P Conclusion Our in vivo contaminated wound model demonstrated that barbed Monofilament Suture performed similarly to Monofilament Suture and better than braided Suture in terms of bacterial adherence, biofilm formation, and tissue reactivity.
C. Diffin - One of the best experts on this subject based on the ideXlab platform.
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POSTERIOR SOFT TISSUE REPAIR IN TOTAL HIP ARTHROPLASTY: A SIMPLE AND CHEAP Suture PASSING TECHNIQUE
2018Co-Authors: C. Diffin, M. Chambers, L. Campton, J. RobertsAbstract:Posterior soft tissue repair is often performed in Total Hip Arthroplasty (THA). Many reports have shown the advantage of posterior soft tissue repair in reducing their prosthetic hip dislocation rates.We describe an easy and inexpensive way of passing Sutures through small drill holes in the Greater Trocanter to re-attach muscle, tendon and capsule in a posterior soft tissue repair.By using a reversed Monofilament Suture on a straight needle held in artery forceps and passing this in a retrograde direction through a drill hole, a Suture capturing device is produced.By capturing the long ends of Sutures tied in the short external rotators and the posterior capsule of the hip through 2 drill holes in the Greater Trochanter, a posterior soft tissue repair can be performed. We have used this technique successfully in over 100 consecutive THAs.We conclude that the use of a Monofilament Suture used in the manner describe is an excellent and inexpensive way to aid in a posterior soft tissue repair in THAs. This...
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POSTERIOR SOFT TISSUE REPAIR IN TOTAL HIP ARTHROPLASTY: A SIMPLE AND CHEAP Suture PASSING TECHNIQUE
Journal of Bone and Joint Surgery-british Volume, 2013Co-Authors: C. Diffin, M. Chambers, L. Campton, J. RobertsAbstract:Posterior soft tissue repair is often performed in Total Hip Arthroplasty (THA). Many reports have shown the advantage of posterior soft tissue repair in reducing their prosthetic hip dislocation rates. We describe an easy and inexpensive way of passing Sutures through small drill holes in the Greater Trocanter to re-attach muscle, tendon and capsule in a posterior soft tissue repair. By using a reversed Monofilament Suture on a straight needle held in artery forceps and passing this in a retrograde direction through a drill hole, a Suture capturing device is produced. By capturing the long ends of Sutures tied in the short external rotators and the posterior capsule of the hip through 2 drill holes in the Greater Trochanter, a posterior soft tissue repair can be performed. We have used this technique successfully in over 100 consecutive THAs. We conclude that the use of a Monofilament Suture used in the manner describe is an excellent and inexpensive way to aid in a posterior soft tissue repair in THAs. This is done without the cost of an additional dedicated Suture passing device. The Suture could also be used in the skin closure if desired.