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Franz M. Geiger - One of the best experts on this subject based on the ideXlab platform.

  • Nonlinear Optical Studies of the Agricultural Antibiotic Morantel Interacting with Silica/Water Interfaces
    Journal of the American Chemical Society, 2005
    Co-Authors: Christopher T. Konek, Kimberly D. Illg, Hind A. Al-abadleh, Andrea B. Voges, Grace Yin, Michael J. Musorrafiti, Catherine M. Schmidt, Franz M. Geiger
    Abstract:

    It is now known that the untreated discharge of pharmaceuticals into the environment can impact human health and development and lead to increased drug resistance in biota. Here, we present the first direct interface-specific studies that address the mobility of the widely used agricultural antibiotic Morantel, which is commonly present in farm runoff. Surface-bound Morantel was spectroscopically identified using second harmonic generation (SHG) via a two-photon resonance of its n−π* transition and in the C−H stretching region by vibrational sum frequency generation (VSFG). Resonantly enhanced SHG adsorption isotherm measurements carried out at the silica/water interface between 6 × 10-7 and 5 × 10-5 M Morantel concentration result in a free energy of adsorption of 42(2) kJ/mol at pH 7. Finally, real-time tracking of Morantel interaction with the silica/water interface shows that the binding events are fully reversible, consistent with its high mobility in silica-rich soil environments. This work thus ind...

  • nonlinear optical studies of the agricultural antibiotic Morantel interacting with silica water interfaces
    Journal of the American Chemical Society, 2005
    Co-Authors: Christopher T. Konek, Kimberly D. Illg, Andrea B. Voges, Grace Yin, Michael J. Musorrafiti, Catherine M. Schmidt, Hind A Alabadleh, Franz M. Geiger
    Abstract:

    It is now known that the untreated discharge of pharmaceuticals into the environment can impact human health and development and lead to increased drug resistance in biota. Here, we present the first direct interface-specific studies that address the mobility of the widely used agricultural antibiotic Morantel, which is commonly present in farm runoff. Surface-bound Morantel was spectroscopically identified using second harmonic generation (SHG) via a two-photon resonance of its n−π* transition and in the C−H stretching region by vibrational sum frequency generation (VSFG). Resonantly enhanced SHG adsorption isotherm measurements carried out at the silica/water interface between 6 × 10-7 and 5 × 10-5 M Morantel concentration result in a free energy of adsorption of 42(2) kJ/mol at pH 7. Finally, real-time tracking of Morantel interaction with the silica/water interface shows that the binding events are fully reversible, consistent with its high mobility in silica-rich soil environments. This work thus ind...

F. H. M. Borgsteede - One of the best experts on this subject based on the ideXlab platform.

  • Further studies with a strain of Ostertagia ostertagi resistant to Morantel tartrate
    International journal for parasitology, 1991
    Co-Authors: F. H. M. Borgsteede
    Abstract:

    Two experiments with a Morantel resistant strain of Ostertagia ostertagi were carried out. In the first experiment five groups of five calves were infected with 60,000 larvae of this resistant strain. Calves of one group remained untreated, calves of the other groups were treated with Morantel tartrate, oxfendazole, levamisole or ivermectin in the recommended doses. It was demonstrated that there was side resistance to levamisole, but not to oxfendazole or ivermectin. Compared with the untreated controls the reduction percentages of the worm burdens were 45.3 (Morantel tartrate), 99.7 (oxfendazole), 83.5 (levamisole) and 100 (ivermectin). In the second experiment a comparison was made between the effect of levamisole against a Morantel susceptible strain of O. ostertagi and the resistant strain. Two groups of five calves were infected with the susceptible strain and two groups with the resistant one. One group of each pair remained untreated, the other was treated with levamisole. The reduction percentages of the worm burdens were 99.6 (susceptible strain) and 63.6 (resistant strain). This result confirms the efficacy of levamisole to susceptible O. ostertagi and the side resistance of the Morantel resistant strain.

  • Further studies with a strain of Ostertagia ostertagi resistant to Morantel tartrate
    International journal for parasitology, 1991
    Co-Authors: F. H. M. Borgsteede
    Abstract:

    Abstract Borgsteede F. H. M. 1991. Further studies with a strain of Ostertagia ostertagi resistant to Morantel tartrate. International Journal for Parasitology 21 : 867–870. Two experiments with a Morantel resistant strain of Ostertagia ostertagi were carried out. In the first experiment five groups of five calves were infected with 60,000 larvae of this resistant strain. Calves of one group remained untreated, calves of the other groups were treated with Morantel tartrate, oxfendazole, levamisole or ivermectin in the recommended doses. It was demonstrated that there was side resistance to levamisole, but not to oxfendazole or ivermectin. Compared with the untreated controls the reduction percentages of the worm burdens were 45.3 (Morantel tartrate), 99.7 (oxfendazole), 83.5 (levamisole) and 100 (ivermectin). In the second experiment a comparison was made between the effect of levamisole against a Morantel susceptible strain of O. ostertagi and the resistant strain. Two groups of five calves were infected with the susceptible strain and two groups with the resistant one. One group of each pair remained untreated, the other was treated with levamisole. The reduction percentages of the worm burdens were 99.6 (susceptible strain) and 63.6 (resistant strain). This result confirms the efficacy of levamisole to susceptible O. ostertagi and the side resistance of the Morantel resistant strain.

Christopher T. Konek - One of the best experts on this subject based on the ideXlab platform.

  • Nonlinear Optical Studies of the Agricultural Antibiotic Morantel Interacting with Silica/Water Interfaces
    Journal of the American Chemical Society, 2005
    Co-Authors: Christopher T. Konek, Kimberly D. Illg, Hind A. Al-abadleh, Andrea B. Voges, Grace Yin, Michael J. Musorrafiti, Catherine M. Schmidt, Franz M. Geiger
    Abstract:

    It is now known that the untreated discharge of pharmaceuticals into the environment can impact human health and development and lead to increased drug resistance in biota. Here, we present the first direct interface-specific studies that address the mobility of the widely used agricultural antibiotic Morantel, which is commonly present in farm runoff. Surface-bound Morantel was spectroscopically identified using second harmonic generation (SHG) via a two-photon resonance of its n−π* transition and in the C−H stretching region by vibrational sum frequency generation (VSFG). Resonantly enhanced SHG adsorption isotherm measurements carried out at the silica/water interface between 6 × 10-7 and 5 × 10-5 M Morantel concentration result in a free energy of adsorption of 42(2) kJ/mol at pH 7. Finally, real-time tracking of Morantel interaction with the silica/water interface shows that the binding events are fully reversible, consistent with its high mobility in silica-rich soil environments. This work thus ind...

  • nonlinear optical studies of the agricultural antibiotic Morantel interacting with silica water interfaces
    Journal of the American Chemical Society, 2005
    Co-Authors: Christopher T. Konek, Kimberly D. Illg, Andrea B. Voges, Grace Yin, Michael J. Musorrafiti, Catherine M. Schmidt, Hind A Alabadleh, Franz M. Geiger
    Abstract:

    It is now known that the untreated discharge of pharmaceuticals into the environment can impact human health and development and lead to increased drug resistance in biota. Here, we present the first direct interface-specific studies that address the mobility of the widely used agricultural antibiotic Morantel, which is commonly present in farm runoff. Surface-bound Morantel was spectroscopically identified using second harmonic generation (SHG) via a two-photon resonance of its n−π* transition and in the C−H stretching region by vibrational sum frequency generation (VSFG). Resonantly enhanced SHG adsorption isotherm measurements carried out at the silica/water interface between 6 × 10-7 and 5 × 10-5 M Morantel concentration result in a free energy of adsorption of 42(2) kJ/mol at pH 7. Finally, real-time tracking of Morantel interaction with the silica/water interface shows that the binding events are fully reversible, consistent with its high mobility in silica-rich soil environments. This work thus ind...

Grace Yin - One of the best experts on this subject based on the ideXlab platform.

  • Nonlinear Optical Studies of the Agricultural Antibiotic Morantel Interacting with Silica/Water Interfaces
    Journal of the American Chemical Society, 2005
    Co-Authors: Christopher T. Konek, Kimberly D. Illg, Hind A. Al-abadleh, Andrea B. Voges, Grace Yin, Michael J. Musorrafiti, Catherine M. Schmidt, Franz M. Geiger
    Abstract:

    It is now known that the untreated discharge of pharmaceuticals into the environment can impact human health and development and lead to increased drug resistance in biota. Here, we present the first direct interface-specific studies that address the mobility of the widely used agricultural antibiotic Morantel, which is commonly present in farm runoff. Surface-bound Morantel was spectroscopically identified using second harmonic generation (SHG) via a two-photon resonance of its n−π* transition and in the C−H stretching region by vibrational sum frequency generation (VSFG). Resonantly enhanced SHG adsorption isotherm measurements carried out at the silica/water interface between 6 × 10-7 and 5 × 10-5 M Morantel concentration result in a free energy of adsorption of 42(2) kJ/mol at pH 7. Finally, real-time tracking of Morantel interaction with the silica/water interface shows that the binding events are fully reversible, consistent with its high mobility in silica-rich soil environments. This work thus ind...

  • nonlinear optical studies of the agricultural antibiotic Morantel interacting with silica water interfaces
    Journal of the American Chemical Society, 2005
    Co-Authors: Christopher T. Konek, Kimberly D. Illg, Andrea B. Voges, Grace Yin, Michael J. Musorrafiti, Catherine M. Schmidt, Hind A Alabadleh, Franz M. Geiger
    Abstract:

    It is now known that the untreated discharge of pharmaceuticals into the environment can impact human health and development and lead to increased drug resistance in biota. Here, we present the first direct interface-specific studies that address the mobility of the widely used agricultural antibiotic Morantel, which is commonly present in farm runoff. Surface-bound Morantel was spectroscopically identified using second harmonic generation (SHG) via a two-photon resonance of its n−π* transition and in the C−H stretching region by vibrational sum frequency generation (VSFG). Resonantly enhanced SHG adsorption isotherm measurements carried out at the silica/water interface between 6 × 10-7 and 5 × 10-5 M Morantel concentration result in a free energy of adsorption of 42(2) kJ/mol at pH 7. Finally, real-time tracking of Morantel interaction with the silica/water interface shows that the binding events are fully reversible, consistent with its high mobility in silica-rich soil environments. This work thus ind...

Hind A Alabadleh - One of the best experts on this subject based on the ideXlab platform.

  • nonlinear optical studies of the agricultural antibiotic Morantel interacting with silica water interfaces
    Journal of the American Chemical Society, 2005
    Co-Authors: Christopher T. Konek, Kimberly D. Illg, Andrea B. Voges, Grace Yin, Michael J. Musorrafiti, Catherine M. Schmidt, Hind A Alabadleh, Franz M. Geiger
    Abstract:

    It is now known that the untreated discharge of pharmaceuticals into the environment can impact human health and development and lead to increased drug resistance in biota. Here, we present the first direct interface-specific studies that address the mobility of the widely used agricultural antibiotic Morantel, which is commonly present in farm runoff. Surface-bound Morantel was spectroscopically identified using second harmonic generation (SHG) via a two-photon resonance of its n−π* transition and in the C−H stretching region by vibrational sum frequency generation (VSFG). Resonantly enhanced SHG adsorption isotherm measurements carried out at the silica/water interface between 6 × 10-7 and 5 × 10-5 M Morantel concentration result in a free energy of adsorption of 42(2) kJ/mol at pH 7. Finally, real-time tracking of Morantel interaction with the silica/water interface shows that the binding events are fully reversible, consistent with its high mobility in silica-rich soil environments. This work thus ind...