The Experts below are selected from a list of 120 Experts worldwide ranked by ideXlab platform
C Rose - One of the best experts on this subject based on the ideXlab platform.
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Eosinophilic Ulcer of the Mouth mucosa. Differential Mouth Ulcer diagnosis
Hautarzt, 2020Co-Authors: J. Schmitt-köppler, Eva-bettina Bröcker, C RoseAbstract:Das eosinophile Ulkus der Mundschleimhaut ist eine seltene, selbstlimitierende Erkrankung unklarer Genese. In der Regel treten Einzellasionen in der Mundhohle oder an den Lippen auf. Der Verlauf ist charakterisiert durch eine kurze Anamnese und eine spontane Abheilung. Die Diagnose wird histologisch gestellt. Man findet ein tiefreichendes gemischtzelliges Entzundungsinfiltrat mit reichlich eosinophilen Granulozyten. Klinisch zeigt sich ein meist schmerzloses, weislich-gelblich belegtes Ulkus mit derbem aufgeworfenem Randwall oder ein zentral ulzerierter Tumor ohne Lymphadenopathie. Differenzialdiagnostisch ist in erster Linie an einen malignen Tumor oder auch an das Primarstadium der Lues zu denken.
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eosinophilic Ulcer of the Mouth mucosa differential Mouth Ulcer diagnosis
Hautarzt, 2002Co-Authors: J Schmittkoppler, Eva-bettina Bröcker, C RoseAbstract:: Eosinophilic Ulcers of the oral mucosa represent a rare, self-limiting disease of unknown origin. Single lesions occur typically in the oral cavity or on the lower lip. Characteristically, they have a short history and resolve spontaneously. Diagnosis is verified by the histologic feature of a deep polymorphic inflammatory infiltrate with numerous eosinophils. The clinical aspect shows a usually nontender Ulcer with a white or yellowish base and elevated indurated borders or a tumor with central Ulceration. Lymphadenopathy is not found. Differential diagnoses include malignant tumors and the primary stage of syphilis. We present three cases recently diagnosed in our department to show the characteristics and the different appearances of the disease. A 74-year-old woman presented with an Ulcer at the base of the tongue, a 59-year-old man had one on the lower lip, and in a 48-year-old man the lesion was atypically located at the edge of the Mouth. Here we demonstrate the importance of knowledge of the disease, its course, and the characteristic histology to avoid troublesome diagnostic and therapeutic procedures.
Bin Duan - One of the best experts on this subject based on the ideXlab platform.
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large scale and rapid preparation of nanofibrous meshes and their application for drug loaded multilayer mucoadhesive patch fabrication for Mouth Ulcer treatment
ACS Applied Materials & Interfaces, 2019Co-Authors: Shaohua Wu, Amy Aldrich, Tammy Kielian, Mark A Carlson, Bin DuanAbstract:Electrospinning provides a simple and convenient method to fabricate nanofibrous meshes. However, the nanofiber productivity is often limited to the laboratory scale, which cannot satisfy the requi...
Eva-bettina Bröcker - One of the best experts on this subject based on the ideXlab platform.
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Eosinophilic Ulcer of the Mouth mucosa. Differential Mouth Ulcer diagnosis
Hautarzt, 2020Co-Authors: J. Schmitt-köppler, Eva-bettina Bröcker, C RoseAbstract:Das eosinophile Ulkus der Mundschleimhaut ist eine seltene, selbstlimitierende Erkrankung unklarer Genese. In der Regel treten Einzellasionen in der Mundhohle oder an den Lippen auf. Der Verlauf ist charakterisiert durch eine kurze Anamnese und eine spontane Abheilung. Die Diagnose wird histologisch gestellt. Man findet ein tiefreichendes gemischtzelliges Entzundungsinfiltrat mit reichlich eosinophilen Granulozyten. Klinisch zeigt sich ein meist schmerzloses, weislich-gelblich belegtes Ulkus mit derbem aufgeworfenem Randwall oder ein zentral ulzerierter Tumor ohne Lymphadenopathie. Differenzialdiagnostisch ist in erster Linie an einen malignen Tumor oder auch an das Primarstadium der Lues zu denken.
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eosinophilic Ulcer of the Mouth mucosa differential Mouth Ulcer diagnosis
Hautarzt, 2002Co-Authors: J Schmittkoppler, Eva-bettina Bröcker, C RoseAbstract:: Eosinophilic Ulcers of the oral mucosa represent a rare, self-limiting disease of unknown origin. Single lesions occur typically in the oral cavity or on the lower lip. Characteristically, they have a short history and resolve spontaneously. Diagnosis is verified by the histologic feature of a deep polymorphic inflammatory infiltrate with numerous eosinophils. The clinical aspect shows a usually nontender Ulcer with a white or yellowish base and elevated indurated borders or a tumor with central Ulceration. Lymphadenopathy is not found. Differential diagnoses include malignant tumors and the primary stage of syphilis. We present three cases recently diagnosed in our department to show the characteristics and the different appearances of the disease. A 74-year-old woman presented with an Ulcer at the base of the tongue, a 59-year-old man had one on the lower lip, and in a 48-year-old man the lesion was atypically located at the edge of the Mouth. Here we demonstrate the importance of knowledge of the disease, its course, and the characteristic histology to avoid troublesome diagnostic and therapeutic procedures.
Meng-wong Taing - One of the best experts on this subject based on the ideXlab platform.
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Exploring oral healthcare management across Australian community pharmacies using case vignettes.
Community Dentistry and Oral Epidemiology, 2019Co-Authors: Meng-wong Taing, Pauline J. Ford, Norman Firth, Christopher FreemanAbstract:In Australia, more than 80% of pharmacists and pharmacy assistants are consulted for oral healthcare advice up to five times or more each week. This study assesses Australian community pharmacy staff's (pharmacists and pharmacy assistants) ability to recognize and manage common oral health presentations using case vignettes, and determine whether appropriate identification and management are associated with self-reported confidence. Five oral healthcare case vignettes were developed based on previous literature by a multidisciplinary team of dental and pharmacy practitioner academics. Topics included pulpitis, gingivitis, oral hygiene advice for a toddler, a Mouth Ulcer and a dry Mouth scenario. Pharmacies were randomly selected from each Australian State and Territory and community pharmacy staff invited to complete the case vignettes. A total of 312 and 932 case vignettes were completed by pharmacy assistants and pharmacists, respectively. Approximately one-third of staff appropriately identified a non-healing Mouth Ulcer and up to 16% recognized a pulpitis (inflamed dental pulp) presentation. Provision of best practice or evidence-based recommendations were reported in up to 28%, 19%, 57% and 31% of pharmacy staff offering appropriate advice and guidance for pulpitis, gingivitis, a non-healing Mouth Ulcer and oral health promotion messages, respectively. No participants provided all best practice recommendations for drug-induced xerostomia. In all five vignettes, confidence was not associated with best practice recommendations and was only modestly associated with improved rates for recognizing gingivitis symptoms. To allow community pharmacists and assistants to fulfil their role as important members of the oral healthcare team, additional training and support are required to facilitate improved recognition of common oral health presentations and to offer recommendations which are in line with current best practice guidelines.
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Investigating the management of potentially cancerous nonhealing Mouth Ulcers in Australian community pharmacies
Health & Social Care in The Community, 2018Co-Authors: Brigitte Janse Van Rensburg, Christopher Freeman, Pauline J. Ford, Meng-wong TaingAbstract:: We sought to examine the management and referral of nonhealing Mouth Ulcer presentations in Australian community pharmacies in the Greater Brisbane region. Trained simulated patients visited 220 randomly selected community pharmacies within the Greater Brisbane region in 2016. Simulated patients enacted two nonhealing (>1 month) Mouth Ulcer scenarios: A direct product request (DPR) (n = 110) and a symptom-based request (SBR) (n = 110). Results were documented and evaluated against Australian national pharmacy practice standards. Referral rates for pharmacy staff (pharmacist, pharmacy assistant or mixed-pharmacist and assistant) were also assessed. Australian pharmacy practice standards recommend staff ask six key questions during SBR and DPR consultations to enable informed decision-making. Two questions relating to identifying the patient and their symptoms were asked in the majority of interactions (76% and 69% respectively); the remaining four questions relating to symptom duration, treatments tried, other medications, and medical conditions were enquired in only 32%, 53%, 31%, and 27% of interactions, respectively. Simulated patients were referred to the doctor/dentist in only 11.8% of all interactions (both scenarios requiring referral). Overall, staff handling of nonhealing Mouth Ulcer consultations was suboptimal compared to national professional standards. In particular, duration of the nonhealing Mouth Ulcer was enquired in less than one-third of consultations potentially resulting in low referral rates by staff. This study identifies the need for increased oral cancer awareness and education for community pharmacy staff and reinforcing the importance of practising according to professional standards to effectively screen for potentially cancerous nonhealing Mouth lesions.
Shaohua Wu - One of the best experts on this subject based on the ideXlab platform.
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large scale and rapid preparation of nanofibrous meshes and their application for drug loaded multilayer mucoadhesive patch fabrication for Mouth Ulcer treatment
ACS Applied Materials & Interfaces, 2019Co-Authors: Shaohua Wu, Amy Aldrich, Tammy Kielian, Mark A Carlson, Bin DuanAbstract:Electrospinning provides a simple and convenient method to fabricate nanofibrous meshes. However, the nanofiber productivity is often limited to the laboratory scale, which cannot satisfy the requi...