The Experts below are selected from a list of 252 Experts worldwide ranked by ideXlab platform
Lalita Ramakrishnan - One of the best experts on this subject based on the ideXlab platform.
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evaluation of the pathogenesis and treatment of Mycobacterium marinum infection in zebrafish
Nature Protocols, 2013Co-Authors: Kevin Takaki, Muse J Davis, Kathryn Winglee, Lalita RamakrishnanAbstract:Evaluation of the pathogenesis and treatment of Mycobacterium marinum infection in zebrafish
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Mycobacterium marinum Infection of the Hand
2009Co-Authors: Lalita RamakrishnanAbstract:Figure 1. A 35-year-old laboratory researcher who was working with Mycobacterium marinum abraded the back of her left hand, and a tender, erythematous nodule developed (Panel A). Over the next few days, small amounts of yellowish fluid were discharged from the lesion and a line of tender, nodular lymphangitis appeared, extending from the medial aspect of the elbow approximately one third of the way up the arm. The nodules were approximately 0.5 cm in diameter, and there was no erythema of the surrounding skin. Gram's staining and acid-fast staining of the discharge from the lesion revealed inflammatory cells but no . . .
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Using Mycobacterium marinum and its hosts to study tuberculosis
Current Science, 2004Co-Authors: Lalita RamakrishnanAbstract:Mycobacterium marinum, a close relative of Mycobacterium tuberculosis is being used to study mycobacterial pathogenesis. M. marinum causes a systemic tuberculosis-like infection and disease in ectotherms such as frogs andfish. This review describes the development of M. marinum as a model pathogen and the more recent development of genetically tractable model hosts, namely the zebrafish, Drosophila and Dictyostellium to dissect the complex host-pathogen interactions that lead to tuberculosis.
Naomi Schlesinger - One of the best experts on this subject based on the ideXlab platform.
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Mycobacterium marinum arthritis mimicking rheumatoid arthritis
The Journal of Rheumatology, 2006Co-Authors: Wadie Toma, Naomi SchlesingerAbstract:Mycobacterium marinum is an atypical Mycobacterium found in salt and fresh water. M. marinum infection occurs following skin trauma in fresh or salt water and usually presents as a localized granuloma or sporotrichotic lymphangitis. It rarely affects the musculoskeletal system. We describe a patient who presented with subcutaneous nodules and an inflammatory arthritis that was thought to be rheumatoid arthritis, and was treated as such with corticosteroids, methotrexate, and anti-tumor necrosis factor-alpha therapy, with worsening of his arthritis.
Karyn L. Sutton - One of the best experts on this subject based on the ideXlab platform.
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A second-order high-resolution finite difference scheme for a size-structured model for the spread of Mycobacterium marinum
Journal of Biological Dynamics, 2020Co-Authors: Azmy S. Ackleh, Mark L. Delcambre, Karyn L. SuttonAbstract:We present a second-order high-resolution finite difference scheme to approximate the solution of a mathematical model of the transmission dynamics of Mycobacterium marinum (Mm) in an aquatic environment. This work extends the numerical theory and continues the preliminary studies on the model first developed in Ackleh et al. [Structured models for the spread of Mycobacterium marinum: foundations for a numerical approximation scheme, Math. Biosci. Eng. 11 (2014), pp. 679–721]. Numerical simulations demonstrating the accuracy of the method are presented, and we compare this scheme to the first-order scheme developed in Ackleh et al. [Structured models for the spread of Mycobacterium marinum: foundations for a numerical approximation scheme, Math. Biosci. Eng. 11 (2014), pp. 679–721] to show that the first-order method requires significantly more computational time to provide solutions with a similar accuracy. We also demonstrated that the model can be a tool to understand surprising or nonintuitive phenome...
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A second-order high-resolution finite difference scheme for a size-structured model for the spread of Mycobacterium marinum.
Journal of biological dynamics, 2014Co-Authors: Azmy S. Ackleh, Mark L. Delcambre, Karyn L. SuttonAbstract:We present a second-order high-resolution finite difference scheme to approximate the solution of a mathematical model of the transmission dynamics of Mycobacterium marinum (Mm) in an aquatic environment. This work extends the numerical theory and continues the preliminary studies on the model first developed in Ackleh et al. [Structured models for the spread of Mycobacterium marinum: foundations for a numerical approximation scheme, Math. Biosci. Eng. 11 (2014), pp. 679-721]. Numerical simulations demonstrating the accuracy of the method are presented, and we compare this scheme to the first-order scheme developed in Ackleh et al. [Structured models for the spread of Mycobacterium marinum: foundations for a numerical approximation scheme, Math. Biosci. Eng. 11 (2014), pp. 679-721] to show that the first-order method requires significantly more computational time to provide solutions with a similar accuracy. We also demonstrated that the model can be a tool to understand surprising or nonintuitive phenomena regarding competitive advantage in the context of biologically realistic growth, birth and death rates.
Wadie Toma - One of the best experts on this subject based on the ideXlab platform.
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Mycobacterium marinum arthritis mimicking rheumatoid arthritis
The Journal of Rheumatology, 2006Co-Authors: Wadie Toma, Naomi SchlesingerAbstract:Mycobacterium marinum is an atypical Mycobacterium found in salt and fresh water. M. marinum infection occurs following skin trauma in fresh or salt water and usually presents as a localized granuloma or sporotrichotic lymphangitis. It rarely affects the musculoskeletal system. We describe a patient who presented with subcutaneous nodules and an inflammatory arthritis that was thought to be rheumatoid arthritis, and was treated as such with corticosteroids, methotrexate, and anti-tumor necrosis factor-alpha therapy, with worsening of his arthritis.
Kevin Takaki - One of the best experts on this subject based on the ideXlab platform.
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evaluation of the pathogenesis and treatment of Mycobacterium marinum infection in zebrafish
Nature Protocols, 2013Co-Authors: Kevin Takaki, Muse J Davis, Kathryn Winglee, Lalita RamakrishnanAbstract:Evaluation of the pathogenesis and treatment of Mycobacterium marinum infection in zebrafish
