The Experts below are selected from a list of 876 Experts worldwide ranked by ideXlab platform
Harmita H. - One of the best experts on this subject based on the ideXlab platform.
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Optimasi Biotransformasi Total Sterol Limbah Tahu Menggunakan Mycobacterium phlei Dsm 43286 Menjadi 1,4-androstadien-3,17-dion, Dengan Pengaruh Variasi Konsentrasi Inhibitor a, a\u27- Dipiridil
'Universitas Islam Indonesia (Islamic University of Indonesia)', 2004Co-Authors: Kurniadi M., Tambunan U. S., Harmita H.Abstract:Isolation of total sterol from waste product of soy bean cake has been conducted, followed by biotransformation to 1,4-androstadien-3,17-dione (ADD). The waste product consist of; β-sitosterol, stigmasterol, kaemfesterol, which are isolated by column chromatography technique using silica gel as stationary phase and chloroform as mobile phase. Biotransformation was conducted by using Mycobacterium phlei DSM 43286 in the present of α, α’- dipiridil as an inhibitor with concentration of 0,5; 1; 1,5; 2,0 mM. The main product of biotransformation were ADD and pregnenolon. The optimum yield of ADD 0,48% is achieved by adding 1,5 mM α, α’- dipiridil are two hours after addition of substrate and 72 hours of incubation time
Harmita Harmita - One of the best experts on this subject based on the ideXlab platform.
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OPTIMASI BIOTRANSFORMASI TOTAL STEROL LIMBAH TAHU MENGGUNAKAN Mycobacterium phlei DSM 43286 MENJADI 1,4-ANDROSTADIEN-3,17-DION, DENGAN PENGARUH VARIASI KONSENTRASI INHIBITOR A, A’- DIPIRIDIL
'Universitas Indonesia Directorate of Research and Public Service', 2012Co-Authors: Kurniadi Maryati, Tambunan Usman, Harmita HarmitaAbstract:Isolation of total sterol from waste product of soy bean cake has been conducted, followed by biotransformation to 1,4-androstadien-3,17-dione (ADD). The waste product consist of; β-sitosterol, stigmasterol, kaemfesterol, which are isolated by column chromatography technique using silica gel as stationary phase and chloroform as mobile phase. Biotransformation was conducted by using Mycobacterium phlei DSM 43286 in the present of α, α’- dipiridil as an inhibitor with concentration of 0,5; 1; 1,5; 2,0 mM. The main product of biotransformation were ADD and pregnenolon. The optimum yield of ADD 0,48% is achieved by adding 1,5 mM α, α’- dipiridil are two hours after addition of substrate and 72 hours of incubation time. Key Words: Mycobacterium phlei DSM 43286; α, α’- dipiridil concentra- tions
Venkatesh Devaru - One of the best experts on this subject based on the ideXlab platform.
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synthesis structure activity relationship of iodinated 4 aryloxymethyl coumarins as potential anti cancer and anti mycobacterial agents
European Journal of Medicinal Chemistry, 2014Co-Authors: Mahantesha Basanagouda, Vishwanath B Jambagi, Nivedita N Barigidad, Sandeep S Laxmeshwar, Venkatesh DevaruAbstract:Abstract A series of new iodinated-4-aryloxymethylcoumarins 6, 8 and 10 have been obtained from the reaction of various 4-bromomethylcoumarins 4 with 2-iodophenol 5, 3-iodophenol 7 and 4-iodophenol 9 respectively. All the title compounds were screened for anticancer activity against two cancer cell lines (MDA-MB human adenocarcinoma mammary gland and A-549 human lung carcinoma) and two mycobacterial strains (Mycobacterium tuberculosis H37 RV and Mycobacterium phlei). The SAR results indicate that nine compounds are potent, among these 10h and 10i having chlorine are most effective. This is the first report assigning in vitro anti-mycobacterial, anticancer and structure–activity relationship for this new class of iodinated-4-aryloxymethyl-coumarins.
Kurniadi M. - One of the best experts on this subject based on the ideXlab platform.
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Optimasi Biotransformasi Total Sterol Limbah Tahu Menggunakan Mycobacterium phlei Dsm 43286 Menjadi 1,4-androstadien-3,17-dion, Dengan Pengaruh Variasi Konsentrasi Inhibitor a, a\u27- Dipiridil
'Universitas Islam Indonesia (Islamic University of Indonesia)', 2004Co-Authors: Kurniadi M., Tambunan U. S., Harmita H.Abstract:Isolation of total sterol from waste product of soy bean cake has been conducted, followed by biotransformation to 1,4-androstadien-3,17-dione (ADD). The waste product consist of; β-sitosterol, stigmasterol, kaemfesterol, which are isolated by column chromatography technique using silica gel as stationary phase and chloroform as mobile phase. Biotransformation was conducted by using Mycobacterium phlei DSM 43286 in the present of α, α’- dipiridil as an inhibitor with concentration of 0,5; 1; 1,5; 2,0 mM. The main product of biotransformation were ADD and pregnenolon. The optimum yield of ADD 0,48% is achieved by adding 1,5 mM α, α’- dipiridil are two hours after addition of substrate and 72 hours of incubation time
Kurniadi Maryati - One of the best experts on this subject based on the ideXlab platform.
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OPTIMASI BIOTRANSFORMASI TOTAL STEROL LIMBAH TAHU MENGGUNAKAN Mycobacterium phlei DSM 43286 MENJADI 1,4-ANDROSTADIEN-3,17-DION, DENGAN PENGARUH VARIASI KONSENTRASI INHIBITOR A, A’- DIPIRIDIL
'Universitas Indonesia Directorate of Research and Public Service', 2012Co-Authors: Kurniadi Maryati, Tambunan Usman, Harmita HarmitaAbstract:Isolation of total sterol from waste product of soy bean cake has been conducted, followed by biotransformation to 1,4-androstadien-3,17-dione (ADD). The waste product consist of; β-sitosterol, stigmasterol, kaemfesterol, which are isolated by column chromatography technique using silica gel as stationary phase and chloroform as mobile phase. Biotransformation was conducted by using Mycobacterium phlei DSM 43286 in the present of α, α’- dipiridil as an inhibitor with concentration of 0,5; 1; 1,5; 2,0 mM. The main product of biotransformation were ADD and pregnenolon. The optimum yield of ADD 0,48% is achieved by adding 1,5 mM α, α’- dipiridil are two hours after addition of substrate and 72 hours of incubation time. Key Words: Mycobacterium phlei DSM 43286; α, α’- dipiridil concentra- tions
