The Experts below are selected from a list of 279 Experts worldwide ranked by ideXlab platform
Eduardo M Richter - One of the best experts on this subject based on the ideXlab platform.
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a batch injection analysis system with square wave voltammetric detection for fast and simultaneous determination of Naphazoline and zinc
Talanta, 2016Co-Authors: Thiago Oliveira, Jhonys Machado Freitas, Rodrigo A A Munoz, Eduardo M RichterAbstract:In this work, a batch-injection analysis system with square-wave voltammetric (BIA-SWV) detection was applied for the first time to the simultaneous determination of inorganic (zinc) and organic (Naphazoline) species. Both compounds were detected in a single run (70 injections h(-1)) with a small injection volume (∼100 µL). The calibration curves exhibited linear response range between 3.0 and 21.0 μmol L(-1) (r=0.999) for Naphazoline and between 10.0 and 60.0 μmol L(-1) (r=0.992) for zinc. The detection limits were 0.13 and 0.04 μmol L(-1) for zinc and Naphazoline, respectively. Good reproducibility was achieved for multiple measurements of a solution containing both species (RSD<1.0%; n=20). The results obtained with the BIA-SWV method for the simultaneous determination of Naphazoline and zinc were compared to those obtained by HPLC (Naphazoline) and by FAAS (zinc); no statistically significant differences were observed (95% confidence level).
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A batch injection analysis system with square-wave voltammetric detection for fast and simultaneous determination of Naphazoline and zinc.
Talanta, 2016Co-Authors: Thiago Oliveira, Jhonys Machado Freitas, Rodrigo A A Munoz, Eduardo M RichterAbstract:In this work, a batch-injection analysis system with square-wave voltammetric (BIA-SWV) detection was applied for the first time to the simultaneous determination of inorganic (zinc) and organic (Naphazoline) species. Both compounds were detected in a single run (70 injections h(-1)) with a small injection volume (∼100 µL). The calibration curves exhibited linear response range between 3.0 and 21.0 μmol L(-1) (r=0.999) for Naphazoline and between 10.0 and 60.0 μmol L(-1) (r=0.992) for zinc. The detection limits were 0.13 and 0.04 μmol L(-1) for zinc and Naphazoline, respectively. Good reproducibility was achieved for multiple measurements of a solution containing both species (RSD
Thiago Oliveira - One of the best experts on this subject based on the ideXlab platform.
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a batch injection analysis system with square wave voltammetric detection for fast and simultaneous determination of Naphazoline and zinc
Talanta, 2016Co-Authors: Thiago Oliveira, Jhonys Machado Freitas, Rodrigo A A Munoz, Eduardo M RichterAbstract:In this work, a batch-injection analysis system with square-wave voltammetric (BIA-SWV) detection was applied for the first time to the simultaneous determination of inorganic (zinc) and organic (Naphazoline) species. Both compounds were detected in a single run (70 injections h(-1)) with a small injection volume (∼100 µL). The calibration curves exhibited linear response range between 3.0 and 21.0 μmol L(-1) (r=0.999) for Naphazoline and between 10.0 and 60.0 μmol L(-1) (r=0.992) for zinc. The detection limits were 0.13 and 0.04 μmol L(-1) for zinc and Naphazoline, respectively. Good reproducibility was achieved for multiple measurements of a solution containing both species (RSD<1.0%; n=20). The results obtained with the BIA-SWV method for the simultaneous determination of Naphazoline and zinc were compared to those obtained by HPLC (Naphazoline) and by FAAS (zinc); no statistically significant differences were observed (95% confidence level).
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A batch injection analysis system with square-wave voltammetric detection for fast and simultaneous determination of Naphazoline and zinc.
Talanta, 2016Co-Authors: Thiago Oliveira, Jhonys Machado Freitas, Rodrigo A A Munoz, Eduardo M RichterAbstract:In this work, a batch-injection analysis system with square-wave voltammetric (BIA-SWV) detection was applied for the first time to the simultaneous determination of inorganic (zinc) and organic (Naphazoline) species. Both compounds were detected in a single run (70 injections h(-1)) with a small injection volume (∼100 µL). The calibration curves exhibited linear response range between 3.0 and 21.0 μmol L(-1) (r=0.999) for Naphazoline and between 10.0 and 60.0 μmol L(-1) (r=0.992) for zinc. The detection limits were 0.13 and 0.04 μmol L(-1) for zinc and Naphazoline, respectively. Good reproducibility was achieved for multiple measurements of a solution containing both species (RSD
Reza Hajian - One of the best experts on this subject based on the ideXlab platform.
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simultaneous determination of Naphazoline and antazoline in eye drop formulations using net analyte signal standard addition method nassam and partial least squares pls
2014Co-Authors: Reza Hajian, Abdol Mohammad Ghaedi, Vali Zare Shahabadi, Hadiss Izadi, Mitra ZafariAbstract:Two chemometrics methods consisting of net analyte signal standard addition method (NASSAM) and Partial least-squares algorithm (PLS)-1 presented for the simultaneous spectrophotometric determination of Naphazoline (NAP) and Antazoline (ANT) with overlapping spectra. NASSAM combines the advantages of the standard addition method with the net analyte signal concept which enables the extraction of information concerning a certain analyte from spectra of multi-component mixtures. This method has some advantages such as the use of a full spectrum realization, therefore it does not require calibration and prediction steps and only a few measurements are required for the determination. In PLS-1, agreement between predicted and experimental concentrations was fair (r> 0.99 for NAP and ANT models). The RMSE for prediction set were 8.93 and 13.06 for Naphazoline and antazoline respectively. Therefore, NASSAM is a better model for simultaneous determination of Naphazoline and Antazoline in the presence of each other in comparison with PLS-1. The simultaneous determination of Naphazoline and antazoline was performed in Britton-Robinson buffer (pH 9.0) in the concentration ranges of 1.0 10
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application of ratio derivative spectrophotometry for simultaneous determination of Naphazoline and antazoline in eye drops
E-journal of Chemistry, 2010Co-Authors: Reza Hajian, N Shams, I KaediAbstract:Ratio derivative spectrophotometrie method has been developed for the simultaneous determination of Naphazoline (NAP) and antazoline (ANT) at micromolar levels in Britton Robinson buffer (pH 9) medium. In this method the overlapping spectra of Naphazoline and antazoline were well resolved by making use of the first-derivative of the ratios of their direct absorption spectra. The derivative ratio absorbances of Naphazoline and antazoline were measured at 227.2 and 235 nm, respectively for their quantification. The method is simple, fast and does not require separation of Naphazoline and antazoline. Another salient feature of the method is that simultaneous standard additions of both analytes permitted to resolve matrix effect and quantification at a unique standard addition plot. Naphazoline and antazoline were determined in the concentration range of 10-150 μmol L-1 (NAP/ANT ratio varying from about 10 to 150) in the same aliquot with a precision and accuracy of about 1.7% and 1.8%, respectively. The recommended procedure was successfully applied for analysis of Naphazoline and antazoline in eye drops.
Jhonys Machado Freitas - One of the best experts on this subject based on the ideXlab platform.
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a batch injection analysis system with square wave voltammetric detection for fast and simultaneous determination of Naphazoline and zinc
Talanta, 2016Co-Authors: Thiago Oliveira, Jhonys Machado Freitas, Rodrigo A A Munoz, Eduardo M RichterAbstract:In this work, a batch-injection analysis system with square-wave voltammetric (BIA-SWV) detection was applied for the first time to the simultaneous determination of inorganic (zinc) and organic (Naphazoline) species. Both compounds were detected in a single run (70 injections h(-1)) with a small injection volume (∼100 µL). The calibration curves exhibited linear response range between 3.0 and 21.0 μmol L(-1) (r=0.999) for Naphazoline and between 10.0 and 60.0 μmol L(-1) (r=0.992) for zinc. The detection limits were 0.13 and 0.04 μmol L(-1) for zinc and Naphazoline, respectively. Good reproducibility was achieved for multiple measurements of a solution containing both species (RSD<1.0%; n=20). The results obtained with the BIA-SWV method for the simultaneous determination of Naphazoline and zinc were compared to those obtained by HPLC (Naphazoline) and by FAAS (zinc); no statistically significant differences were observed (95% confidence level).
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A batch injection analysis system with square-wave voltammetric detection for fast and simultaneous determination of Naphazoline and zinc.
Talanta, 2016Co-Authors: Thiago Oliveira, Jhonys Machado Freitas, Rodrigo A A Munoz, Eduardo M RichterAbstract:In this work, a batch-injection analysis system with square-wave voltammetric (BIA-SWV) detection was applied for the first time to the simultaneous determination of inorganic (zinc) and organic (Naphazoline) species. Both compounds were detected in a single run (70 injections h(-1)) with a small injection volume (∼100 µL). The calibration curves exhibited linear response range between 3.0 and 21.0 μmol L(-1) (r=0.999) for Naphazoline and between 10.0 and 60.0 μmol L(-1) (r=0.992) for zinc. The detection limits were 0.13 and 0.04 μmol L(-1) for zinc and Naphazoline, respectively. Good reproducibility was achieved for multiple measurements of a solution containing both species (RSD
Rodrigo A A Munoz - One of the best experts on this subject based on the ideXlab platform.
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a batch injection analysis system with square wave voltammetric detection for fast and simultaneous determination of Naphazoline and zinc
Talanta, 2016Co-Authors: Thiago Oliveira, Jhonys Machado Freitas, Rodrigo A A Munoz, Eduardo M RichterAbstract:In this work, a batch-injection analysis system with square-wave voltammetric (BIA-SWV) detection was applied for the first time to the simultaneous determination of inorganic (zinc) and organic (Naphazoline) species. Both compounds were detected in a single run (70 injections h(-1)) with a small injection volume (∼100 µL). The calibration curves exhibited linear response range between 3.0 and 21.0 μmol L(-1) (r=0.999) for Naphazoline and between 10.0 and 60.0 μmol L(-1) (r=0.992) for zinc. The detection limits were 0.13 and 0.04 μmol L(-1) for zinc and Naphazoline, respectively. Good reproducibility was achieved for multiple measurements of a solution containing both species (RSD<1.0%; n=20). The results obtained with the BIA-SWV method for the simultaneous determination of Naphazoline and zinc were compared to those obtained by HPLC (Naphazoline) and by FAAS (zinc); no statistically significant differences were observed (95% confidence level).
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A batch injection analysis system with square-wave voltammetric detection for fast and simultaneous determination of Naphazoline and zinc.
Talanta, 2016Co-Authors: Thiago Oliveira, Jhonys Machado Freitas, Rodrigo A A Munoz, Eduardo M RichterAbstract:In this work, a batch-injection analysis system with square-wave voltammetric (BIA-SWV) detection was applied for the first time to the simultaneous determination of inorganic (zinc) and organic (Naphazoline) species. Both compounds were detected in a single run (70 injections h(-1)) with a small injection volume (∼100 µL). The calibration curves exhibited linear response range between 3.0 and 21.0 μmol L(-1) (r=0.999) for Naphazoline and between 10.0 and 60.0 μmol L(-1) (r=0.992) for zinc. The detection limits were 0.13 and 0.04 μmol L(-1) for zinc and Naphazoline, respectively. Good reproducibility was achieved for multiple measurements of a solution containing both species (RSD
