The Experts below are selected from a list of 294 Experts worldwide ranked by ideXlab platform
Peter E Andersen - One of the best experts on this subject based on the ideXlab platform.
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high grade malignant transformation of a radiation naive Nasopharyngeal Angiofibroma
Head and Neck-journal for The Sciences and Specialties of The Head and Neck, 2016Co-Authors: Jordan J. Allensworth, Scott H Troob, Christian Lanciault, Peter E AndersenAbstract:Background Nasopharyngeal Angiofibromas are typically considered benign vascular neoplasms, with descriptions of high-grade sarcomatous change found only in lesions with prior radiotherapy. Methods and Results We describe the first reported case of high-grade malignant change in a Nasopharyngeal Angiofibroma naive to radiation. A 45-year-old man presented with left-sided nasal congestion and fullness and was found to have a left-sided Nasopharyngeal mass with intracranial extension on CT scan. A biopsy of the mass revealed Nasopharyngeal Angiofibroma. The patient opted for MRI surveillance, which revealed interval growth 3 years later. Decompression surgery revealed only Angiofibroma, but resection 9 months later demonstrated high-grade sarcoma and concomitant Angiofibroma. The patient had residual disease which progressed through chemoradiation, and is now pursuing clinical trial enrollment. Conclusion Malignant transformation of Nasopharyngeal Angiofibroma is extremely rare. As highlighted by this report, high-grade undifferentiated lesions may arise in tumors without previous radiation. © 2016 Wiley Periodicals, Inc. Head Neck, 2016
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High-grade malignant transformation of a radiation-naïve Nasopharyngeal Angiofibroma.
Head & neck, 2016Co-Authors: Jordan J. Allensworth, Scott H Troob, Christian Lanciault, Peter E AndersenAbstract:Nasopharyngeal Angiofibromas are typically considered benign vascular neoplasms, with descriptions of high-grade sarcomatous change found only in lesions with prior radiotherapy. We describe the first reported case of high-grade malignant change in a Nasopharyngeal Angiofibroma naive to radiation. A 45-year-old man presented with left-sided nasal congestion and fullness and was found to have a left-sided Nasopharyngeal mass with intracranial extension on CT scan. A biopsy of the mass revealed Nasopharyngeal Angiofibroma. The patient opted for MRI surveillance, which revealed interval growth 3 years later. Decompression surgery revealed only Angiofibroma, but resection 9 months later demonstrated high-grade sarcoma and concomitant Angiofibroma. The patient had residual disease which progressed through chemoradiation, and is now pursuing clinical trial enrollment. Malignant transformation of Nasopharyngeal Angiofibroma is extremely rare. As highlighted by this report, high-grade undifferentiated lesions may arise in tumors without previous radiation. © 2016 Wiley Periodicals, Inc. Head Neck 38: E2425-E2427, 2016. © 2016 Wiley Periodicals, Inc.
Antonio Greco - One of the best experts on this subject based on the ideXlab platform.
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Nasopharyngeal Angiofibroma in an elderly female patient a rare case report
Current Opinion in Clinical Nutrition and Metabolic Care, 2018Co-Authors: Massimo Ralli, Massimo Fusconi, Irene Claudia Visconti, Salvatore Martellucci, Marco De Vincentiis, Antonio GrecoAbstract:‘Juvenile’ Nasopharyngeal Angiofibroma, which accounts for <1% of all head and neck neoplasms, occurs predominantly in males between 10 and 18 years of age. The small number of patients older than 30 years confirms that presentation after this age is exceptional. Only rare cases of Nasopharyngeal Angiofibroma in female patients have been documented to date, and some authors believe that sex chromosome studies are indicated in such cases. The pathogenesis of Nasopharyngeal Angiofibroma remains unknown, but it has been hypothesized that it is a testosterone-dependent tumor. We herein report a particularly rare case of a 68-year-old woman diagnosed with Nasopharyngeal Angiofibroma and describe the diagnostic and therapeutic workup. This case describes, to the best of our knowledge, the oldest patient reported in the literature.
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Nasopharyngeal Angiofibroma in an elderly female patient: A rare case report
Molecular and clinical oncology, 2018Co-Authors: Massimo Ralli, Massimo Fusconi, Irene Claudia Visconti, Salvatore Martellucci, Marco De Vincentiis, Antonio GrecoAbstract:‘Juvenile’ Nasopharyngeal Angiofibroma, which accounts for
Jordan J. Allensworth - One of the best experts on this subject based on the ideXlab platform.
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high grade malignant transformation of a radiation naive Nasopharyngeal Angiofibroma
Head and Neck-journal for The Sciences and Specialties of The Head and Neck, 2016Co-Authors: Jordan J. Allensworth, Scott H Troob, Christian Lanciault, Peter E AndersenAbstract:Background Nasopharyngeal Angiofibromas are typically considered benign vascular neoplasms, with descriptions of high-grade sarcomatous change found only in lesions with prior radiotherapy. Methods and Results We describe the first reported case of high-grade malignant change in a Nasopharyngeal Angiofibroma naive to radiation. A 45-year-old man presented with left-sided nasal congestion and fullness and was found to have a left-sided Nasopharyngeal mass with intracranial extension on CT scan. A biopsy of the mass revealed Nasopharyngeal Angiofibroma. The patient opted for MRI surveillance, which revealed interval growth 3 years later. Decompression surgery revealed only Angiofibroma, but resection 9 months later demonstrated high-grade sarcoma and concomitant Angiofibroma. The patient had residual disease which progressed through chemoradiation, and is now pursuing clinical trial enrollment. Conclusion Malignant transformation of Nasopharyngeal Angiofibroma is extremely rare. As highlighted by this report, high-grade undifferentiated lesions may arise in tumors without previous radiation. © 2016 Wiley Periodicals, Inc. Head Neck, 2016
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High-grade malignant transformation of a radiation-naïve Nasopharyngeal Angiofibroma.
Head & neck, 2016Co-Authors: Jordan J. Allensworth, Scott H Troob, Christian Lanciault, Peter E AndersenAbstract:Nasopharyngeal Angiofibromas are typically considered benign vascular neoplasms, with descriptions of high-grade sarcomatous change found only in lesions with prior radiotherapy. We describe the first reported case of high-grade malignant change in a Nasopharyngeal Angiofibroma naive to radiation. A 45-year-old man presented with left-sided nasal congestion and fullness and was found to have a left-sided Nasopharyngeal mass with intracranial extension on CT scan. A biopsy of the mass revealed Nasopharyngeal Angiofibroma. The patient opted for MRI surveillance, which revealed interval growth 3 years later. Decompression surgery revealed only Angiofibroma, but resection 9 months later demonstrated high-grade sarcoma and concomitant Angiofibroma. The patient had residual disease which progressed through chemoradiation, and is now pursuing clinical trial enrollment. Malignant transformation of Nasopharyngeal Angiofibroma is extremely rare. As highlighted by this report, high-grade undifferentiated lesions may arise in tumors without previous radiation. © 2016 Wiley Periodicals, Inc. Head Neck 38: E2425-E2427, 2016. © 2016 Wiley Periodicals, Inc.
Shi Run-ji - One of the best experts on this subject based on the ideXlab platform.
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Clinical value of pre-operative double embolization for Nasopharyngeal Angiofibroma
Journal of Interventional Radiology, 2006Co-Authors: Shi Run-jiAbstract:Objective To evaluate the clinical value of pre-operative double embolization for Nasopharyngeal Angiofibroma. Methods Digital subtraction angiography(DSA) was carried out in 7 cases of Nasopharyngeal Angiofibroma. In six cases,the supplying arteries originated from the maxillary artery and the branches arising from internal carotid artery underwent double embolization-direct percutaneous puncture embolization and selective embolization of blood supplying arteries. In another case,the supplying artery originated from maxillary artery was only undertaken selective embolization for the feeding arteries. Results All the tumor masses reduced in vonlume obviously or even disappeared on the angiography after embolization. Conclusions Pre-operative double embolization for Nasopharyngeal Angiofibroma could be a necessary additional treatment method. (J Intervent Radiol,2006,15: 342-344)
Roberto Delfini - One of the best experts on this subject based on the ideXlab platform.
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The surgical approaches to Nasopharyngeal Angiofibroma.
Journal of Cranio-maxillofacial Surgery, 1994Co-Authors: Giorgio Iannetti, Evaristo Belli, Francesco Saverio De Ponte, Cicconetti A, Roberto DelfiniAbstract:Summary After a short summary of the aetiopathogenesis, the routes of extension and the diagnostic features of Nasopharyngeal Angiofibroma, the importance of early diagnosis and careful surgical planning is underlined. In particular the extension and topographic localization allows the choice of the best approach to optimize surgical radicality—the prime concern in the treatment of Nasopharyngeal Angiofibroma. Different surgical approaches are proposed for the tumour removal according to our experience in 17 patients.
