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Yoshinobu Shigekawa - One of the best experts on this subject based on the ideXlab platform.
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The characteristics of pancreatic Neck Cancer.
Journal of Clinical Oncology, 2016Co-Authors: Hiroki Yamaue, Seiko Hirono, Manabu Kawai, Ken-ichi Okada, Motoki Miyazawa, Atsushi Shimizu, Yuji Kitahata, Masaki Ueno, Shinya Hayami, Yoshinobu ShigekawaAbstract:337 Background: Pancreatic Neck Cancer occurs in the small region surrounded by the common hepatic artery (CHA), gastroduodenal artery (GDA), and portal vein (PV). The specific clinicopathological characteristics of pancreatic Neck Cancer remain unclear. This study aimed to identify specific biological behaviors of pancreatic Neck Cancer for the improvement of treatment outcomes. Methods: This study was a retrospective cohort study and comparative outcomes design. In 63 (19.4%) of 325 consecutive pancreatic Cancer patients who underwent surgery, the tumor was located in the pancreatic Neck. Clinicopathological characteristics and prognostic factors specific to pancreatic Neck Cancer were analyzed by comparison to those of pancreatic head or body/tail Cancers. Results: The rates of radiographic and pathological PV and/or superior mesenteric vein (PV/SMV) invasion were higher in patients with pancreatic Neck Cancer (radiographic: 84.1%, pathological: 36.5%) than those with pancreatic head and body/tail canc...
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Prognostic factors of pancreatic Neck Cancer.
Journal of Clinical Oncology, 2014Co-Authors: Seiko Hirono, Manabu Kawai, Ken-ichi Okada, Motoki Miyazawa, Atsushi Shimizu, Yuji Kitahata, Masaki Ueno, Shinya Hayami, Masaji Tani, Yoshinobu ShigekawaAbstract:355 Background: Pancreatic Neck Cancer is surrounded by common hepatic artery (CHA), gastroduodenal artery (GDA) and portal vein (PV), and easily invades nerve plexus around main arteries, such as CHA, celiac trunk, and superior mesenteric artery (SMA). Therefore, the resectablity of pancreatic Neck Cancer is low, and the biological behaviors have been unclear. In this study, we reviewed 59 resected pancreatic Neck Cancer cases to identify the prognostic factors. Methods: From 2000 to 2012, 305 patients with pancreatic Cancer underwent surgical resection, and in 59 patients (19%) among them with pancreatic Neck Cancer, 49 patients underwent pancreatoduodenectomy, 5 subtotal pancreatectomy, 4 distal pancreatectomy with en-bloc celiac axis, and 1 total pancreatectomy. We defined borderline resectable pancreatic Cancer as tumor abutted CHA, celiac trunk, or SMA, and classified radiographic types of PV invasion into A (normal), B (unilateral), C (bilateral), or D (complete obstruction) by CT imaging. We analy...
Barbara A. Murphy - One of the best experts on this subject based on the ideXlab platform.
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Prevalence of Secondary Lymphedema in Patients With Head and Neck Cancer
Journal of pain and symptom management, 2011Co-Authors: Jie Deng, Sheila H. Ridner, Mary S. Dietrich, Nancy Wells, Kenneth A. Wallston, Robert J. Sinard, Anthony J. Cmelak, Barbara A. MurphyAbstract:Abstract Context Because surgery, radiation, and/or chemotherapy disrupt lymphatic structures, damage soft tissue leading to scar tissue formation and fibrosis, and further affect lymphatic function, patients with head and Neck Cancer may be at high risk for developing secondary lymphedema. Yet, no published data are available regarding the prevalence of secondary lymphedema after head and Neck Cancer treatment. Objectives The aim of this study was to examine prevalence of secondary lymphedema in patients with head and Neck Cancer. Methods The study included 81 patients with head and Neck Cancer who were three months or more post-treatment. External lymphedema was staged using Foldi's lymphedema scale. Internal lymphedema was identified through a flexible fiber-optic endoscopic or mirror examination. Patterson's scale was used to grade degrees of internal lymphedema. Results Of the 81 patients, 75.3% (61 of 81) had some form of late-effect lymphedema. Of those, 9.8% (6 of 61) only had external, 39.4% (24 of 61) only had internal, and 50.8% (31 of 61) had both types. Conclusion Lymphedema is a common late effect in patients with head and Neck Cancer, and it develops in multiple external and internal anatomical locations. During physical examination and endoscopic procedures, clinicians should assess patients with head and Neck Cancer for late-effect lymphedema. Referral for treatment should be considered when lymphedema is noted. Research is needed to examine risk factors of lymphedema in patients with head and Neck Cancer and its effects on patients' symptoms, function, and quality of life.
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Lymphedema in patients with head and Neck Cancer.
Oncology nursing forum, 2010Co-Authors: Jie Deng, Sheila H. Ridner, Barbara A. MurphyAbstract:PURPOSE/OBJECTIVES to describe the current state of the science on secondary lymphedema in patients with head and Neck Cancer. DATA SOURCES published journal articles and books and data from the National Cancer Institute, the American Cancer Society, and other healthcare-related professional association Web sites. DATA SYNTHESIS survivors of head and Neck Cancer may develop secondary lymphedema as a result of the Cancer or its treatment. Secondary lymphedema may involve external (e.g., submental area) and internal (e.g., laryngeal, pharyngeal, oral cavity) structures. Although lymphedema affects highly visible anatomic sites (e.g., face, Neck), and profoundly influences critical physical functions (e.g., speech, breathing, swallowing, cervical range of motion), research regarding this issue is lacking. Studies are needed to address a variety of vital questions, including incidence and prevalence, optimal measurement techniques, associated symptom burden, functional loss, and psychosocial impact. CONCLUSIONS secondary lymphedema in patients with head and Neck Cancer is a significant but understudied issue. IMPLICATIONS FOR NURSING a need exists to systematically examine secondary lymphedema related to treatment for head and Neck Cancer and address gaps in the current literature, such as symptom burden, effects on body functions, and influences on quality of life. Oncology nurses and other healthcare professionals should have empirical evidence to help them manage lymphedema after head and Neck Cancer treatment.
Seiko Hirono - One of the best experts on this subject based on the ideXlab platform.
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The characteristics of pancreatic Neck Cancer.
Journal of Clinical Oncology, 2016Co-Authors: Hiroki Yamaue, Seiko Hirono, Manabu Kawai, Ken-ichi Okada, Motoki Miyazawa, Atsushi Shimizu, Yuji Kitahata, Masaki Ueno, Shinya Hayami, Yoshinobu ShigekawaAbstract:337 Background: Pancreatic Neck Cancer occurs in the small region surrounded by the common hepatic artery (CHA), gastroduodenal artery (GDA), and portal vein (PV). The specific clinicopathological characteristics of pancreatic Neck Cancer remain unclear. This study aimed to identify specific biological behaviors of pancreatic Neck Cancer for the improvement of treatment outcomes. Methods: This study was a retrospective cohort study and comparative outcomes design. In 63 (19.4%) of 325 consecutive pancreatic Cancer patients who underwent surgery, the tumor was located in the pancreatic Neck. Clinicopathological characteristics and prognostic factors specific to pancreatic Neck Cancer were analyzed by comparison to those of pancreatic head or body/tail Cancers. Results: The rates of radiographic and pathological PV and/or superior mesenteric vein (PV/SMV) invasion were higher in patients with pancreatic Neck Cancer (radiographic: 84.1%, pathological: 36.5%) than those with pancreatic head and body/tail canc...
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Prognostic factors of pancreatic Neck Cancer.
Journal of Clinical Oncology, 2014Co-Authors: Seiko Hirono, Manabu Kawai, Ken-ichi Okada, Motoki Miyazawa, Atsushi Shimizu, Yuji Kitahata, Masaki Ueno, Shinya Hayami, Masaji Tani, Yoshinobu ShigekawaAbstract:355 Background: Pancreatic Neck Cancer is surrounded by common hepatic artery (CHA), gastroduodenal artery (GDA) and portal vein (PV), and easily invades nerve plexus around main arteries, such as CHA, celiac trunk, and superior mesenteric artery (SMA). Therefore, the resectablity of pancreatic Neck Cancer is low, and the biological behaviors have been unclear. In this study, we reviewed 59 resected pancreatic Neck Cancer cases to identify the prognostic factors. Methods: From 2000 to 2012, 305 patients with pancreatic Cancer underwent surgical resection, and in 59 patients (19%) among them with pancreatic Neck Cancer, 49 patients underwent pancreatoduodenectomy, 5 subtotal pancreatectomy, 4 distal pancreatectomy with en-bloc celiac axis, and 1 total pancreatectomy. We defined borderline resectable pancreatic Cancer as tumor abutted CHA, celiac trunk, or SMA, and classified radiographic types of PV invasion into A (normal), B (unilateral), C (bilateral), or D (complete obstruction) by CT imaging. We analy...
Motoki Miyazawa - One of the best experts on this subject based on the ideXlab platform.
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The characteristics of pancreatic Neck Cancer.
Journal of Clinical Oncology, 2016Co-Authors: Hiroki Yamaue, Seiko Hirono, Manabu Kawai, Ken-ichi Okada, Motoki Miyazawa, Atsushi Shimizu, Yuji Kitahata, Masaki Ueno, Shinya Hayami, Yoshinobu ShigekawaAbstract:337 Background: Pancreatic Neck Cancer occurs in the small region surrounded by the common hepatic artery (CHA), gastroduodenal artery (GDA), and portal vein (PV). The specific clinicopathological characteristics of pancreatic Neck Cancer remain unclear. This study aimed to identify specific biological behaviors of pancreatic Neck Cancer for the improvement of treatment outcomes. Methods: This study was a retrospective cohort study and comparative outcomes design. In 63 (19.4%) of 325 consecutive pancreatic Cancer patients who underwent surgery, the tumor was located in the pancreatic Neck. Clinicopathological characteristics and prognostic factors specific to pancreatic Neck Cancer were analyzed by comparison to those of pancreatic head or body/tail Cancers. Results: The rates of radiographic and pathological PV and/or superior mesenteric vein (PV/SMV) invasion were higher in patients with pancreatic Neck Cancer (radiographic: 84.1%, pathological: 36.5%) than those with pancreatic head and body/tail canc...
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Prognostic factors of pancreatic Neck Cancer.
Journal of Clinical Oncology, 2014Co-Authors: Seiko Hirono, Manabu Kawai, Ken-ichi Okada, Motoki Miyazawa, Atsushi Shimizu, Yuji Kitahata, Masaki Ueno, Shinya Hayami, Masaji Tani, Yoshinobu ShigekawaAbstract:355 Background: Pancreatic Neck Cancer is surrounded by common hepatic artery (CHA), gastroduodenal artery (GDA) and portal vein (PV), and easily invades nerve plexus around main arteries, such as CHA, celiac trunk, and superior mesenteric artery (SMA). Therefore, the resectablity of pancreatic Neck Cancer is low, and the biological behaviors have been unclear. In this study, we reviewed 59 resected pancreatic Neck Cancer cases to identify the prognostic factors. Methods: From 2000 to 2012, 305 patients with pancreatic Cancer underwent surgical resection, and in 59 patients (19%) among them with pancreatic Neck Cancer, 49 patients underwent pancreatoduodenectomy, 5 subtotal pancreatectomy, 4 distal pancreatectomy with en-bloc celiac axis, and 1 total pancreatectomy. We defined borderline resectable pancreatic Cancer as tumor abutted CHA, celiac trunk, or SMA, and classified radiographic types of PV invasion into A (normal), B (unilateral), C (bilateral), or D (complete obstruction) by CT imaging. We analy...
Ken-ichi Okada - One of the best experts on this subject based on the ideXlab platform.
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The characteristics of pancreatic Neck Cancer.
Journal of Clinical Oncology, 2016Co-Authors: Hiroki Yamaue, Seiko Hirono, Manabu Kawai, Ken-ichi Okada, Motoki Miyazawa, Atsushi Shimizu, Yuji Kitahata, Masaki Ueno, Shinya Hayami, Yoshinobu ShigekawaAbstract:337 Background: Pancreatic Neck Cancer occurs in the small region surrounded by the common hepatic artery (CHA), gastroduodenal artery (GDA), and portal vein (PV). The specific clinicopathological characteristics of pancreatic Neck Cancer remain unclear. This study aimed to identify specific biological behaviors of pancreatic Neck Cancer for the improvement of treatment outcomes. Methods: This study was a retrospective cohort study and comparative outcomes design. In 63 (19.4%) of 325 consecutive pancreatic Cancer patients who underwent surgery, the tumor was located in the pancreatic Neck. Clinicopathological characteristics and prognostic factors specific to pancreatic Neck Cancer were analyzed by comparison to those of pancreatic head or body/tail Cancers. Results: The rates of radiographic and pathological PV and/or superior mesenteric vein (PV/SMV) invasion were higher in patients with pancreatic Neck Cancer (radiographic: 84.1%, pathological: 36.5%) than those with pancreatic head and body/tail canc...
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Prognostic factors of pancreatic Neck Cancer.
Journal of Clinical Oncology, 2014Co-Authors: Seiko Hirono, Manabu Kawai, Ken-ichi Okada, Motoki Miyazawa, Atsushi Shimizu, Yuji Kitahata, Masaki Ueno, Shinya Hayami, Masaji Tani, Yoshinobu ShigekawaAbstract:355 Background: Pancreatic Neck Cancer is surrounded by common hepatic artery (CHA), gastroduodenal artery (GDA) and portal vein (PV), and easily invades nerve plexus around main arteries, such as CHA, celiac trunk, and superior mesenteric artery (SMA). Therefore, the resectablity of pancreatic Neck Cancer is low, and the biological behaviors have been unclear. In this study, we reviewed 59 resected pancreatic Neck Cancer cases to identify the prognostic factors. Methods: From 2000 to 2012, 305 patients with pancreatic Cancer underwent surgical resection, and in 59 patients (19%) among them with pancreatic Neck Cancer, 49 patients underwent pancreatoduodenectomy, 5 subtotal pancreatectomy, 4 distal pancreatectomy with en-bloc celiac axis, and 1 total pancreatectomy. We defined borderline resectable pancreatic Cancer as tumor abutted CHA, celiac trunk, or SMA, and classified radiographic types of PV invasion into A (normal), B (unilateral), C (bilateral), or D (complete obstruction) by CT imaging. We analy...
