The Experts below are selected from a list of 3 Experts worldwide ranked by ideXlab platform
Zhijiang Zhang - One of the best experts on this subject based on the ideXlab platform.
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asymmetric synthesis and absolute stereochemistry of a labdane type diterpenoid isolated from the rhizomes of isodan yuennanensis
Organic and Biomolecular Chemistry, 2016Co-Authors: Heping Deng, Zhijiang ZhangAbstract:The first synthesis of a labdane-type diterpenoid isolated from Isodon yuennanensis was achieved in fourteen steps from commercially available starting material, (+)-sclareolide. The synthesis features the Barton Nitrite Ester reaction to introduce an oxime at the angular methyl group and the Jones oxidation to construct the lactone segment. By comparison of the optical rotation of our synthetic sample and the natural sample, the absolute stereochemistry of the natural diterpenoid has been determined.
Heping Deng - One of the best experts on this subject based on the ideXlab platform.
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asymmetric synthesis and absolute stereochemistry of a labdane type diterpenoid isolated from the rhizomes of isodan yuennanensis
Organic and Biomolecular Chemistry, 2016Co-Authors: Heping Deng, Zhijiang ZhangAbstract:The first synthesis of a labdane-type diterpenoid isolated from Isodon yuennanensis was achieved in fourteen steps from commercially available starting material, (+)-sclareolide. The synthesis features the Barton Nitrite Ester reaction to introduce an oxime at the angular methyl group and the Jones oxidation to construct the lactone segment. By comparison of the optical rotation of our synthetic sample and the natural sample, the absolute stereochemistry of the natural diterpenoid has been determined.