The Experts below are selected from a list of 237 Experts worldwide ranked by ideXlab platform
Nagatoshi Nishiwaki - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of functionalized 4-Nitroanilines by ring transformation of dinitropyridone with enaminones
Tetrahedron Letters, 2017Co-Authors: Saki Naito, Haruyasu Asahara, Soichi Yokoyama, Nagatoshi NishiwakiAbstract:Abstract 2-Functionalized 4-Nitroanilines were readily synthesized by ring transformation using 3,5-dinitro-2-pyridone and enaminones prepared from 1,3-dicarbonyl compounds and amines. Modification of the amino group and the ortho -position could be achieved by simply changing the enaminones. Using this strategy, functional groups such as acetyl, benzoyl, and ethoxycarbonyl groups could be introduced into the Nitroaniline framework.
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tailor made synthesis of n n 2 6 tetrasubstituted 4 Nitroanilines by three component ring transformation of dinitropyridone
European Journal of Organic Chemistry, 2015Co-Authors: Haruyasu Asahara, Nagatoshi NishiwakiAbstract:The ring transformation of dinitropyridone afforded various kinds of 2,6-disubstituted-4-Nitroanilines upon treatment with aliphatic ketones in the presence of ammonium acetate as a nitrogen source, wherein dinitropyridone behaved as the synthetic equivalent of unstable nitromalonaldehyde. The benzene ring, as well as the amino group of the Nitroaniline framework, was easily modified by only changing a ketone and the nitrogen source, which afforded N,N,2,6-tetrasubstituted 4-Nitroanilines in good to excellent yields.
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Tailor‐Made Synthesis of N,N,2,6‐Tetrasubstituted 4‐Nitroanilines by Three‐Component Ring Transformation of Dinitropyridone
European Journal of Organic Chemistry, 2015Co-Authors: Haruyasu Asahara, Nagatoshi NishiwakiAbstract:The ring transformation of dinitropyridone afforded various kinds of 2,6-disubstituted-4-Nitroanilines upon treatment with aliphatic ketones in the presence of ammonium acetate as a nitrogen source, wherein dinitropyridone behaved as the synthetic equivalent of unstable nitromalonaldehyde. The benzene ring, as well as the amino group of the Nitroaniline framework, was easily modified by only changing a ketone and the nitrogen source, which afforded N,N,2,6-tetrasubstituted 4-Nitroanilines in good to excellent yields.
Haruyasu Asahara - One of the best experts on this subject based on the ideXlab platform.
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Synthesis of functionalized 4-Nitroanilines by ring transformation of dinitropyridone with enaminones
Tetrahedron Letters, 2017Co-Authors: Saki Naito, Haruyasu Asahara, Soichi Yokoyama, Nagatoshi NishiwakiAbstract:Abstract 2-Functionalized 4-Nitroanilines were readily synthesized by ring transformation using 3,5-dinitro-2-pyridone and enaminones prepared from 1,3-dicarbonyl compounds and amines. Modification of the amino group and the ortho -position could be achieved by simply changing the enaminones. Using this strategy, functional groups such as acetyl, benzoyl, and ethoxycarbonyl groups could be introduced into the Nitroaniline framework.
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tailor made synthesis of n n 2 6 tetrasubstituted 4 Nitroanilines by three component ring transformation of dinitropyridone
European Journal of Organic Chemistry, 2015Co-Authors: Haruyasu Asahara, Nagatoshi NishiwakiAbstract:The ring transformation of dinitropyridone afforded various kinds of 2,6-disubstituted-4-Nitroanilines upon treatment with aliphatic ketones in the presence of ammonium acetate as a nitrogen source, wherein dinitropyridone behaved as the synthetic equivalent of unstable nitromalonaldehyde. The benzene ring, as well as the amino group of the Nitroaniline framework, was easily modified by only changing a ketone and the nitrogen source, which afforded N,N,2,6-tetrasubstituted 4-Nitroanilines in good to excellent yields.
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Tailor‐Made Synthesis of N,N,2,6‐Tetrasubstituted 4‐Nitroanilines by Three‐Component Ring Transformation of Dinitropyridone
European Journal of Organic Chemistry, 2015Co-Authors: Haruyasu Asahara, Nagatoshi NishiwakiAbstract:The ring transformation of dinitropyridone afforded various kinds of 2,6-disubstituted-4-Nitroanilines upon treatment with aliphatic ketones in the presence of ammonium acetate as a nitrogen source, wherein dinitropyridone behaved as the synthetic equivalent of unstable nitromalonaldehyde. The benzene ring, as well as the amino group of the Nitroaniline framework, was easily modified by only changing a ketone and the nitrogen source, which afforded N,N,2,6-tetrasubstituted 4-Nitroanilines in good to excellent yields.
Takahide Mori - One of the best experts on this subject based on the ideXlab platform.
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Human endometrial stromal cells and decidual cells express cluster of differentiation (CD) 13 antigen/aminopeptidase N and CD10 antigen/neutral endopeptidase.
Biology of Reproduction, 1992Co-Authors: Kimitoshi Imai, Michiyuki Maeda, Hiroshi Fujiwara, Kenji Takakura, Hideharu Kanzaki, Norihiko Okamoto, Masatoshi Kariya, Takahide MoriAbstract:With specific monoclonal antibodies, we found that human endomethal stromal cells and decidual cells express two functionrelated surface antigens. Indirect immunofluorescence staining revealed that both endometrial stromal cells and decidual cells during the first trimester of pregnancy expressed cluster of differentiation (CD) 13 antigen and CD1O antigen, which are identical to aminopeptidase N and neutral endopeptidase, respectively. By flow cytometric analysis, CD1 3 antigen was detected on 8293% of the examined cells, and CD1O antigen was detected on 75-93% of the examined cells in endometrial stromal cellenriched preparations. Furthermore, peptidase activity was detected in these cell preparations by an assay based on the hydrolysis of alanine-p-nitroanilide into p-Nitroaniline and alanine.
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human endometrial stromal cells and decidual cells express cluster of differentiation cd 13 antigen aminopeptidase n and cd10 antigen neutral endopeptidase
Biology of Reproduction, 1992Co-Authors: Kimitoshi Imai, Michiyuki Maeda, Hiroshi Fujiwara, Kenji Takakura, Hideharu Kanzaki, Norihiko Okamoto, Masatoshi Kariya, N Emi, Takahide MoriAbstract:With specific monoclonal antibodies, we found that human endomethal stromal cells and decidual cells express two functionrelated surface antigens. Indirect immunofluorescence staining revealed that both endometrial stromal cells and decidual cells during the first trimester of pregnancy expressed cluster of differentiation (CD) 13 antigen and CD1O antigen, which are identical to aminopeptidase N and neutral endopeptidase, respectively. By flow cytometric analysis, CD1 3 antigen was detected on 8293% of the examined cells, and CD1O antigen was detected on 75-93% of the examined cells in endometrial stromal cellenriched preparations. Furthermore, peptidase activity was detected in these cell preparations by an assay based on the hydrolysis of alanine-p-nitroanilide into p-Nitroaniline and alanine.
Kimitoshi Imai - One of the best experts on this subject based on the ideXlab platform.
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Human endometrial stromal cells and decidual cells express cluster of differentiation (CD) 13 antigen/aminopeptidase N and CD10 antigen/neutral endopeptidase.
Biology of Reproduction, 1992Co-Authors: Kimitoshi Imai, Michiyuki Maeda, Hiroshi Fujiwara, Kenji Takakura, Hideharu Kanzaki, Norihiko Okamoto, Masatoshi Kariya, Takahide MoriAbstract:With specific monoclonal antibodies, we found that human endomethal stromal cells and decidual cells express two functionrelated surface antigens. Indirect immunofluorescence staining revealed that both endometrial stromal cells and decidual cells during the first trimester of pregnancy expressed cluster of differentiation (CD) 13 antigen and CD1O antigen, which are identical to aminopeptidase N and neutral endopeptidase, respectively. By flow cytometric analysis, CD1 3 antigen was detected on 8293% of the examined cells, and CD1O antigen was detected on 75-93% of the examined cells in endometrial stromal cellenriched preparations. Furthermore, peptidase activity was detected in these cell preparations by an assay based on the hydrolysis of alanine-p-nitroanilide into p-Nitroaniline and alanine.
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human endometrial stromal cells and decidual cells express cluster of differentiation cd 13 antigen aminopeptidase n and cd10 antigen neutral endopeptidase
Biology of Reproduction, 1992Co-Authors: Kimitoshi Imai, Michiyuki Maeda, Hiroshi Fujiwara, Kenji Takakura, Hideharu Kanzaki, Norihiko Okamoto, Masatoshi Kariya, N Emi, Takahide MoriAbstract:With specific monoclonal antibodies, we found that human endomethal stromal cells and decidual cells express two functionrelated surface antigens. Indirect immunofluorescence staining revealed that both endometrial stromal cells and decidual cells during the first trimester of pregnancy expressed cluster of differentiation (CD) 13 antigen and CD1O antigen, which are identical to aminopeptidase N and neutral endopeptidase, respectively. By flow cytometric analysis, CD1 3 antigen was detected on 8293% of the examined cells, and CD1O antigen was detected on 75-93% of the examined cells in endometrial stromal cellenriched preparations. Furthermore, peptidase activity was detected in these cell preparations by an assay based on the hydrolysis of alanine-p-nitroanilide into p-Nitroaniline and alanine.
Yi-lan Zhang - One of the best experts on this subject based on the ideXlab platform.
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Solid-Liquid Phase Diagram of the Ternary System of p-Nitroaniline + o-Nitroaniline + Ethanol
Journal of Chemical & Engineering Data, 2010Co-Authors: Hongkun Zhao, Fang Zhang, Yi-lan ZhangAbstract:The mutual solubility for the ternary p-Nitroaniline + o-Nitroaniline + ethanol system was measured at (273.15 to 323.15) K. Three isothermal phase diagrams of the system were constructed on the basis of the measured solubilities. The phase diagrams of the ternary system were similar at all temperatures investigated. Two solid phases were formed and confirmed by the Schreinemaker’s wet residue method; one was p-Nitroaniline, and the other was o-Nitroaniline. The crystallization regions of p-Nitroaniline and o-Nitroaniline increase as the temperature decreases. At the same temperature, the crystallization region of p-Nitroaniline is larger than that of o-Nitroaniline.