The Experts below are selected from a list of 18879 Experts worldwide ranked by ideXlab platform
Gerwin J. Puppels - One of the best experts on this subject based on the ideXlab platform.
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Noninvasive Monitoring of nonshunted pulmonary capillary blood flow in the acute respiratory distress syndrome.
Critical Care Medicine, 2000Co-Authors: Karan J.k. Kanhai, Henk Strijdhorst, Jan C. Pompe, Wim P.j. Holland, Gerwin J. PuppelsAbstract:OBJECTIVE: Noninvasive Monitoring of nonshunted pulmonary capillary blood flow, using the alveolar amplitude response technique (AART) in a porcine model of the acute respiratory distress syndrome. DESIGN: Experimental animal study. SETTING: University center for animal experiments. INTERVENTIONS: In 12 mechanically ventilated pigs, the nonshunted pulmonary capillary blood flow was varied by means of lung lavages and the application of positive end-expiratory pressure. MEASUREMENTS AND MAIN RESULTS: Nonshunted pulmonary capillary blood flow was determined by AART. Cardiac output (determined by the thermodilution method) corrected for venous admixture was used for comparison (r2 varied between .58 and .94; p < .01). The trend in the development of nonshunted pulmonary capillary blood flow as measured with AART was in agreement with the trend detected by cardiac output corrected for venous admixture in 92% of all events. CONCLUSIONS: We conclude that AART can be used to monitor changes in nonshunted pulmonary capillary blood flow in cases of acute respiratory distress syndrome Noninvasively and continuously.
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Noninvasive Monitoring of nonshunted pulmonary capillary blood flow in the acute respiratory distress syndrome.
Critical care medicine, 2000Co-Authors: Karan J.k. Kanhai, Henk Strijdhorst, Jan C. Pompe, Wim P.j. Holland, Eveline G. J. Ong, Gerwin J. PuppelsAbstract:Objective: Noninvasive Monitoring of nonshunted pulmonary capillary blood flow, using the alveolar amplitude response technique (AART) in a porcine model of the acute respiratory distress syndrome. Design: Experimental animal study Setting: University center for animal experiments Interventions: In 12 mechanically ventilated pigs, the nonshunted pulmonary capillary blood flow was varied by means of lung lavages and the application of positive end-expiratory pressure. Measurements and Main Results: Nonshunted pulmonary capillary blood flow was determined by AART. Cardiac output (determined by the thermodilution method) corrected for venous admixture was used for comparison (r2 varied between .58 and .94; p
Marvin A. Sackner - One of the best experts on this subject based on the ideXlab platform.
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Noninvasive Monitoring of cardiac output in human neonates and juvenile piglets by inductance cardiography (thoracocardiography).
Journal of critical care, 2002Co-Authors: Konrad E Bloch, Jose A. Adams, Jorge Bassuk, Martin J. Mangino, Marvin A. SacknerAbstract:Purpose: Thoracocardiography has been used in adult patients to Noninvasively estimate changes in cardiac output (CO) by analysis of ventricular volume curves recorded by an inductive plethysmographic transducer encircling the chest at the Jevel of the heart. The purpose of this study was to investigate the potential of thoracocardiography to monitor cardiac output in human neonates and in a small animal model, the juvenile piglet. Materials and Methods: In 6 human premature neonates weighing 1.0 to 1.6 kg the effect of periodic respiration on CO was studied with thoracocardiography. In 9 piglets weighing 8.5 to 10.2 kg changes in CO were estimated simultaneously by thoracocardiography and thermodilution during fluid loading and rapid atrial pacing. Results: In human neonates, CO during breathing was 136% to 320% of the corresponding value during apneas. In piglets, CO by thermodilution ranged from 0.25 to 3.26 L/min. The mean difference in 40 paired estimates of relative changes in CO by thoracocardiography and thermodilution was 3%, limits of agreement (bias ±2 SD) were ±30%. Conclusions: In neonates, increases in CO during respiratory phases of periodic breathing are consistent with expected cardiorespiratory interactions. Thoracocardiography Monitoring changes in CO in piglets with acceptable accuracy. Thoracocardiography holds promise for Noninvasive Monitoring in human neonates but further validation is required.
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Thoracocardiography: Noninvasive Monitoring of Left Ventricular Stroke Volume
Journal of critical care, 1998Co-Authors: Konrad E Bloch, Sumintra Jugoon, Helene De Socarraz, Keith Manning, Marvin A. SacknerAbstract:Abstract Purpose: Thoracocardiography Noninvasively monitors global stroke volume by inductive plethysmographic recording of ventricular volume curves as previously validated by thermodilution. Our purpose was to investigate the potential of thoracocardiography to individually assess stroke volume of the left ventricle. We hypothesized that curves predominantly reflecting left ventricular volume could be obtained by recording waveforms from thoracocardiographic transducers placed at various levels around the chest, and by identifying their origin as the left ventricle if mean expiratory exceeded mean respiratory stroke volumes during spontaneous breathing. Materials and Methods: Stroke volumes obtained by thoracocardiography in normal subjects were compared beat by beat with estimates derived from simultaneous measurements of left ventricular cavity stroke area by echocardiography with automatic boundary detection. Changes in respiratory variations of stroke volumes were analyzed during spontaneous breathing at fixed rate and tidal volume, during mechanical ventilation, and resistive loaded breathing. Results: In 170 comparisons of beat-by-beat stroke volumes, 89% of thoracocardiographic fell within ±20% of echocardiographic estimates. Changes in tidal volume, resistive loaded breathing, and mechanical ventilation induced respiratory variations of thoracocardiographic derived stroke volumes consistent with the known effect of respiratory changes in intrapleural pressure on left ventricular stroke volumes. Conclusions: The results suggest that thoracocardiography Noninvasively tracks changes in left ventricular stroke volumes. Their absolute value may also be monitored if an initial calibration by an independent technique, such as echocardiography, is performed.
Wei R Chen - One of the best experts on this subject based on the ideXlab platform.
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Noninvasive Monitoring of traumatic brain injury and post traumatic rehabilitation with laser induced photoacoustic imaging
Applied Physics Letters, 2007Co-Authors: Sihua Yang, Da Xing, Yeqi Lao, Diwu Yang, Lvming Zeng, Liangzhong Xiang, Wei R ChenAbstract:A photoacoustic imaging system was used for Noninvasive Monitoring of traumatic mouse brain in vivo with high-quality reconstructed images. Traumatic lesions accompanying with hemorrhage in the mouse cortical surface were accurately mapped, and foreign bodies of two small copper wires inserted in the mouse brain were also detected. Furthermore, the time course of morphological changes of cerebral blood during rehabilitation process of a mouse brain with traumatic brain injury was obtained using a series of photoacoustic images. Experimental results demonstrate that photoacoustic technique holds the potential for clinical applications in brain trauma and cerebrovascular disease detection.
Karan J.k. Kanhai - One of the best experts on this subject based on the ideXlab platform.
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Noninvasive Monitoring of nonshunted pulmonary capillary blood flow in the acute respiratory distress syndrome.
Critical Care Medicine, 2000Co-Authors: Karan J.k. Kanhai, Henk Strijdhorst, Jan C. Pompe, Wim P.j. Holland, Gerwin J. PuppelsAbstract:OBJECTIVE: Noninvasive Monitoring of nonshunted pulmonary capillary blood flow, using the alveolar amplitude response technique (AART) in a porcine model of the acute respiratory distress syndrome. DESIGN: Experimental animal study. SETTING: University center for animal experiments. INTERVENTIONS: In 12 mechanically ventilated pigs, the nonshunted pulmonary capillary blood flow was varied by means of lung lavages and the application of positive end-expiratory pressure. MEASUREMENTS AND MAIN RESULTS: Nonshunted pulmonary capillary blood flow was determined by AART. Cardiac output (determined by the thermodilution method) corrected for venous admixture was used for comparison (r2 varied between .58 and .94; p < .01). The trend in the development of nonshunted pulmonary capillary blood flow as measured with AART was in agreement with the trend detected by cardiac output corrected for venous admixture in 92% of all events. CONCLUSIONS: We conclude that AART can be used to monitor changes in nonshunted pulmonary capillary blood flow in cases of acute respiratory distress syndrome Noninvasively and continuously.
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Noninvasive Monitoring of nonshunted pulmonary capillary blood flow in the acute respiratory distress syndrome.
Critical care medicine, 2000Co-Authors: Karan J.k. Kanhai, Henk Strijdhorst, Jan C. Pompe, Wim P.j. Holland, Eveline G. J. Ong, Gerwin J. PuppelsAbstract:Objective: Noninvasive Monitoring of nonshunted pulmonary capillary blood flow, using the alveolar amplitude response technique (AART) in a porcine model of the acute respiratory distress syndrome. Design: Experimental animal study Setting: University center for animal experiments Interventions: In 12 mechanically ventilated pigs, the nonshunted pulmonary capillary blood flow was varied by means of lung lavages and the application of positive end-expiratory pressure. Measurements and Main Results: Nonshunted pulmonary capillary blood flow was determined by AART. Cardiac output (determined by the thermodilution method) corrected for venous admixture was used for comparison (r2 varied between .58 and .94; p
Konrad E Bloch - One of the best experts on this subject based on the ideXlab platform.
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Noninvasive Monitoring of cardiac output during exercise by inductance cardiography.
Medicine and Science in Sports and Exercise, 2003Co-Authors: Vladimir Kaplan, Guido B. Bucklar, Konrad E BlochAbstract:KAPLAN, V., G. B. BUCKLAR, and K. E. BLOCH. Noninvasive Monitoring of Cardiac Output during Exercise by Inductance Cardiography. Med. Sci. Sports Exerc., Vol. 35, No. 5, pp. 747–752, 2003. Introduction/Purpose: Inductance cardiography is a Noninvasive technique that monitors changes in cardiac output from an inductance plethysmographic transducer encircling the chest at the level of the heart. The method has been previously validated in supine patients at rest by comparisons to thermodilution. Our purpose was to investigate whether the technique can be employed during bicycle exercise. Methods: We simultaneously measured cardiac output by inductance cardiography and by two gas exchange methods based on the Fick principle during upright cycle ergometry in healthy volunteers. Results: In 11 subjects, comparisons of changes in cardiac output by inductance cardiography agreed well with values measured by carbon dioxide rebreathing during a steady-state exercise protocol. In 12 subjects, cardiac output changes measured by inductance cardiography and an oxygen uptake method agreed closely during a progressive ramp exercise protocol to exhaustion. The bias (mean difference to reference methods) and limits of agreement (±2 SD of bias) for estimation of relative changes in cardiac output by inductance cardiography were 1% ± 21% in 67 comparisons to the carbon dioxide rebreathing technique, and 0% ± 22% in 98 comparisons to the oxygen uptake method. Conclusion: In healthy subjects, inductance cardiography accurately and unobtrusively estimates changes in cardiac output during bicycle exercise in comparison to gas exchange methods.
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Noninvasive Monitoring of cardiac output in human neonates and juvenile piglets by inductance cardiography (thoracocardiography).
Journal of critical care, 2002Co-Authors: Konrad E Bloch, Jose A. Adams, Jorge Bassuk, Martin J. Mangino, Marvin A. SacknerAbstract:Purpose: Thoracocardiography has been used in adult patients to Noninvasively estimate changes in cardiac output (CO) by analysis of ventricular volume curves recorded by an inductive plethysmographic transducer encircling the chest at the Jevel of the heart. The purpose of this study was to investigate the potential of thoracocardiography to monitor cardiac output in human neonates and in a small animal model, the juvenile piglet. Materials and Methods: In 6 human premature neonates weighing 1.0 to 1.6 kg the effect of periodic respiration on CO was studied with thoracocardiography. In 9 piglets weighing 8.5 to 10.2 kg changes in CO were estimated simultaneously by thoracocardiography and thermodilution during fluid loading and rapid atrial pacing. Results: In human neonates, CO during breathing was 136% to 320% of the corresponding value during apneas. In piglets, CO by thermodilution ranged from 0.25 to 3.26 L/min. The mean difference in 40 paired estimates of relative changes in CO by thoracocardiography and thermodilution was 3%, limits of agreement (bias ±2 SD) were ±30%. Conclusions: In neonates, increases in CO during respiratory phases of periodic breathing are consistent with expected cardiorespiratory interactions. Thoracocardiography Monitoring changes in CO in piglets with acceptable accuracy. Thoracocardiography holds promise for Noninvasive Monitoring in human neonates but further validation is required.
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Thoracocardiography: Noninvasive Monitoring of Left Ventricular Stroke Volume
Journal of critical care, 1998Co-Authors: Konrad E Bloch, Sumintra Jugoon, Helene De Socarraz, Keith Manning, Marvin A. SacknerAbstract:Abstract Purpose: Thoracocardiography Noninvasively monitors global stroke volume by inductive plethysmographic recording of ventricular volume curves as previously validated by thermodilution. Our purpose was to investigate the potential of thoracocardiography to individually assess stroke volume of the left ventricle. We hypothesized that curves predominantly reflecting left ventricular volume could be obtained by recording waveforms from thoracocardiographic transducers placed at various levels around the chest, and by identifying their origin as the left ventricle if mean expiratory exceeded mean respiratory stroke volumes during spontaneous breathing. Materials and Methods: Stroke volumes obtained by thoracocardiography in normal subjects were compared beat by beat with estimates derived from simultaneous measurements of left ventricular cavity stroke area by echocardiography with automatic boundary detection. Changes in respiratory variations of stroke volumes were analyzed during spontaneous breathing at fixed rate and tidal volume, during mechanical ventilation, and resistive loaded breathing. Results: In 170 comparisons of beat-by-beat stroke volumes, 89% of thoracocardiographic fell within ±20% of echocardiographic estimates. Changes in tidal volume, resistive loaded breathing, and mechanical ventilation induced respiratory variations of thoracocardiographic derived stroke volumes consistent with the known effect of respiratory changes in intrapleural pressure on left ventricular stroke volumes. Conclusions: The results suggest that thoracocardiography Noninvasively tracks changes in left ventricular stroke volumes. Their absolute value may also be monitored if an initial calibration by an independent technique, such as echocardiography, is performed.
