The Experts below are selected from a list of 96 Experts worldwide ranked by ideXlab platform
Tadashi Sugawara - One of the best experts on this subject based on the ideXlab platform.
-
a recursive vesicle based model protocell with a primitive model cell cycle
Nature Communications, 2015Co-Authors: Kensuke Kurihara, Yusaku Okura, Muneyuki Matsuo, Taro Toyota, Kentaro Suzuki, Tadashi SugawaraAbstract:Self-organized lipid structures (protocells) have been proposed as an intermediate between Nonliving Material and cellular life. Synthetic production of model protocells can demonstrate the potential processes by which living cells first arose. While we have previously described a giant vesicle (GV)-based model protocell in which amplification of DNA was linked to self-reproduction, the ability of a protocell to recursively self-proliferate for multiple generations has not been demonstrated. Here we show that newborn daughter GVs can be restored to the status of their parental GVs by pH-induced vesicular fusion of daughter GVs with conveyer GVs filled with depleted substrates. We describe a primitive model cell cycle comprising four discrete phases (ingestion, replication, maturity and division), each of which is selectively activated by a specific external stimulus. The production of recursive self-proliferating model protocells represents a step towards eventual production of model protocells that are able to mimic evolution.
-
A recursive vesicle-based model protocell with a primitive model cell cycle
Nature Communications, 2015Co-Authors: Kensuke Kurihara, Yusaku Okura, Muneyuki Matsuo, Taro Toyota, Kentaro Suzuki, Tadashi SugawaraAbstract:Self-organized lipid structures (protocells) have been proposed as an intermediate between Nonliving Material and cellular life. Synthetic production of model protocells can demonstrate the potential processes by which living cells first arose. While we have previously described a giant vesicle (GV)-based model protocell in which amplification of DNA was linked to self-reproduction, the ability of a protocell to recursively self-proliferate for multiple generations has not been demonstrated. Here we show that newborn daughter GVs can be restored to the status of their parental GVs by pH-induced vesicular fusion of daughter GVs with conveyer GVs filled with depleted substrates. We describe a primitive model cell cycle comprising four discrete phases (ingestion, replication, maturity and division), each of which is selectively activated by a specific external stimulus. The production of recursive self-proliferating model protocells represents a step towards eventual production of model protocells that are able to mimic evolution. The synthetic production of model protocells, which represent potential intermediates between Nonliving Material and living cells, may help to explain the origin of cellular life. Here, Kurihara et al . develop a giant vesicle-based model protocell that is able to self-proliferate recursively in response to external stimuli.
Kentaro Suzuki - One of the best experts on this subject based on the ideXlab platform.
-
a recursive vesicle based model protocell with a primitive model cell cycle
Nature Communications, 2015Co-Authors: Kensuke Kurihara, Yusaku Okura, Muneyuki Matsuo, Taro Toyota, Kentaro Suzuki, Tadashi SugawaraAbstract:Self-organized lipid structures (protocells) have been proposed as an intermediate between Nonliving Material and cellular life. Synthetic production of model protocells can demonstrate the potential processes by which living cells first arose. While we have previously described a giant vesicle (GV)-based model protocell in which amplification of DNA was linked to self-reproduction, the ability of a protocell to recursively self-proliferate for multiple generations has not been demonstrated. Here we show that newborn daughter GVs can be restored to the status of their parental GVs by pH-induced vesicular fusion of daughter GVs with conveyer GVs filled with depleted substrates. We describe a primitive model cell cycle comprising four discrete phases (ingestion, replication, maturity and division), each of which is selectively activated by a specific external stimulus. The production of recursive self-proliferating model protocells represents a step towards eventual production of model protocells that are able to mimic evolution.
-
A recursive vesicle-based model protocell with a primitive model cell cycle
Nature Communications, 2015Co-Authors: Kensuke Kurihara, Yusaku Okura, Muneyuki Matsuo, Taro Toyota, Kentaro Suzuki, Tadashi SugawaraAbstract:Self-organized lipid structures (protocells) have been proposed as an intermediate between Nonliving Material and cellular life. Synthetic production of model protocells can demonstrate the potential processes by which living cells first arose. While we have previously described a giant vesicle (GV)-based model protocell in which amplification of DNA was linked to self-reproduction, the ability of a protocell to recursively self-proliferate for multiple generations has not been demonstrated. Here we show that newborn daughter GVs can be restored to the status of their parental GVs by pH-induced vesicular fusion of daughter GVs with conveyer GVs filled with depleted substrates. We describe a primitive model cell cycle comprising four discrete phases (ingestion, replication, maturity and division), each of which is selectively activated by a specific external stimulus. The production of recursive self-proliferating model protocells represents a step towards eventual production of model protocells that are able to mimic evolution. The synthetic production of model protocells, which represent potential intermediates between Nonliving Material and living cells, may help to explain the origin of cellular life. Here, Kurihara et al . develop a giant vesicle-based model protocell that is able to self-proliferate recursively in response to external stimuli.
Kensuke Kurihara - One of the best experts on this subject based on the ideXlab platform.
-
a recursive vesicle based model protocell with a primitive model cell cycle
Nature Communications, 2015Co-Authors: Kensuke Kurihara, Yusaku Okura, Muneyuki Matsuo, Taro Toyota, Kentaro Suzuki, Tadashi SugawaraAbstract:Self-organized lipid structures (protocells) have been proposed as an intermediate between Nonliving Material and cellular life. Synthetic production of model protocells can demonstrate the potential processes by which living cells first arose. While we have previously described a giant vesicle (GV)-based model protocell in which amplification of DNA was linked to self-reproduction, the ability of a protocell to recursively self-proliferate for multiple generations has not been demonstrated. Here we show that newborn daughter GVs can be restored to the status of their parental GVs by pH-induced vesicular fusion of daughter GVs with conveyer GVs filled with depleted substrates. We describe a primitive model cell cycle comprising four discrete phases (ingestion, replication, maturity and division), each of which is selectively activated by a specific external stimulus. The production of recursive self-proliferating model protocells represents a step towards eventual production of model protocells that are able to mimic evolution.
-
A recursive vesicle-based model protocell with a primitive model cell cycle
Nature Communications, 2015Co-Authors: Kensuke Kurihara, Yusaku Okura, Muneyuki Matsuo, Taro Toyota, Kentaro Suzuki, Tadashi SugawaraAbstract:Self-organized lipid structures (protocells) have been proposed as an intermediate between Nonliving Material and cellular life. Synthetic production of model protocells can demonstrate the potential processes by which living cells first arose. While we have previously described a giant vesicle (GV)-based model protocell in which amplification of DNA was linked to self-reproduction, the ability of a protocell to recursively self-proliferate for multiple generations has not been demonstrated. Here we show that newborn daughter GVs can be restored to the status of their parental GVs by pH-induced vesicular fusion of daughter GVs with conveyer GVs filled with depleted substrates. We describe a primitive model cell cycle comprising four discrete phases (ingestion, replication, maturity and division), each of which is selectively activated by a specific external stimulus. The production of recursive self-proliferating model protocells represents a step towards eventual production of model protocells that are able to mimic evolution. The synthetic production of model protocells, which represent potential intermediates between Nonliving Material and living cells, may help to explain the origin of cellular life. Here, Kurihara et al . develop a giant vesicle-based model protocell that is able to self-proliferate recursively in response to external stimuli.
Mark Henare - One of the best experts on this subject based on the ideXlab platform.
-
Whakapapa as a Maori Mental Construct: Some Implications for the Debate over Genetic Modification of Organisms
The Contemporary Pacific, 2004Co-Authors: Mere Roberts, Bradford Haami, Richard Anthony Benton, Terre Satterfield, Melissa L. Finucane, Mark HenareAbstract:Polynesians possess oral traditions that reveal sophisticated understandings of the world and of their place in it. These typically take the form of an elaborate cosmogony beginning with the origin of the universe and the primal parents, then continuing to trace the descent of living and Nonliving, Material and imMaterial phenomena, including humans. Among New Zealand Maori, such knowledge is encoded and recorded in a mental construct called whakapapa (having an underlying meaning, “to place in layers” [Williams 1975, 259]). In a commonly applied form, that of recording human descent lines and relationships, whakapapa functions as a genealogical table or family pedigree in which the lineages connect each papa or layer (a metaphorical reference to each generation of a family). The extent to which this underlying theoretical rationale for human whakapapa applies to the nonhuman has hitherto remained unexplored, at least in the published literature. To understand the meaning of plant and animal whakapapa requires knowledge of not only plant and animal names but also their accompanying narratives. Typically, these take an allegorical form in which explanatory theories as well as moral principles are explicated. In its totality, Maori use of whakapapa and narrative creates a “metaphysical gestalt” or whole, integrated pattern, for the oral communication of knowledge (Hohepa, pers comm, 1996). Renewed interest in whakapapa in New Zealand arises directly from recent worldwide controversy over the genetic modification (gm) of plants and animals, and, in particular, of transgenic modifications involving the
-
Whakapapa as a Māori Mental Construct: Some Implications for the Debate over Genetic Modification of Organisms." The Contemporary Pacific 16(1
2004Co-Authors: Mere Roberts, Bradford Haami, Terre Satterfield, Melissa L. Finucane, Mark Henare, Richard BentonAbstract:Polynesians possess oral traditions that reveal sophisticated understandings of the world and of their place in it. These typically take the form of an elaborate cosmogony beginning with the origin of the universe and the primal parents, then continuing to trace the descent of living and Nonliving, Material and imMaterial phenomena, including humans. Among New Zealand Mäori, such knowledge is encoded and recorded in a mental construct called whakapapa (having an underlying meaning, “to place in layers ” [Williams 1975, 259]). In a commonly applied form, that of recording human descent lines and relationships, whakapapa functions as a genealogical table or family pedigree in which the lineages connect each papa or layer (a metaphorical reference to each generation of a family). The extent to which this underlying theoretical rationale for human whakapapa applies to the nonhuman has hitherto remained unexplored, at least in the published literature. To understand the meaning of plant and animal whakapapa requires knowledge of not only plant and animal names but also their accompanying narratives. Typically, these take an allegorical form in which explanatory theories as well as moral principles are explicated. In its totality, Mäori use of whakapapa and narrative creates a “metaphysical gestalt ” or whole, integrated pattern, for the oral communication of knowledge (Hohepa, pers comm, 1996). Renewed interest in whakapapa in New Zealand arises directly from recent worldwide controversy over the genetic modification (gm) of plants and animals, and, in particular, of transgenic modifications involving th
Nicolai Mirlean - One of the best experts on this subject based on the ideXlab platform.
-
Calcareous algae bioclast contribution to sediment enrichment by arsenic on the Brazilian subtropical coast
Geo-Marine Letters, 2011Co-Authors: Nicolai Mirlean, Paulo Baisch, Marcelo P. Travassos, Cristina NassarAbstract:Arsenic levels (up to 130 mg kg^−1) substantially exceeding the official threshold have recently been documented in beach and nearshore sediments along more than 50 km of coastline in the Brazilian state of Espírito Santo between 19°50′ and 20°12′S. In an attempt to assess the sources of this enrichment, we performed a study on arsenic distribution in the main mineral substances and living organisms in the beach environment. Laboratory tests on arsenic retention by beach carbonate debris have also been carried out. The data suggest that sedimentary arsenic occurs largely bound to particles of the calcareous red alga Corallina panizzoi , whereby live specimens contained much smaller amounts of this metalloid than was the case for Nonliving Material (2.4 and 20.3 mg kg^−1, respectively). Experimental tests confirmed the ability of C. panizzoi detritus to retain arsenic at pH intervals and ionic strength characteristic of seawater. There are two potential sources of that metalloid for calcareous debris in sediments: brown macroalgae, which were found to contain high levels of As (up to 66.3 mg kg^−1), and ferruginized sandstones (up to 23.0 mg kg^−1). We argue that any contribution of brown algae to beach sediment enrichment by As would be minor, and consider the ferrous sandstones from coastal sedimentary rocks of the Barreiras Group as the principal large-scale source of arsenic in the marine environment of Espírito Santo. The experimental data, together with field studies, corroborate the interpretation that arsenic anomalies in sediments with calcareous debris can form when weathered continental rocks even only slightly enriched in As are leached by marine waters, and the As is at least partially retained by biogenic calcareous detritus in nearshore sediments. Considering that rocks of the Barreiras Group are exposed to marine erosion far to the north of Espírito Santo, we estimate that marine sediments containing calcareous Material are “anomalously” enriched in As along approximately 2,000 km of the Brazilian tropical coastline. Figure Corallina panizzoi -mediated translocation of arsenic in the Espírito Santo coastal environment
-
Calcareous algae bioclast contribution to sediment enrichment by arsenic on the Brazilian subtropical coast
Geo-Marine Letters, 2010Co-Authors: Nicolai Mirlean, Paulo Baisch, Marcelo P. Travassos, Cristina Aparecida Gomes NassarAbstract:Arsenic levels (up to 130 mg kg−1) substantially exceeding the official threshold have recently been documented in beach and nearshore sediments along more than 50 km of coastline in the Brazilian state of Espirito Santo between 19°50′ and 20°12′S. In an attempt to assess the sources of this enrichment, we performed a study on arsenic distribution in the main mineral substances and living organisms in the beach environment. Laboratory tests on arsenic retention by beach carbonate debris have also been carried out. The data suggest that sedimentary arsenic occurs largely bound to particles of the calcareous red alga Corallina panizzoi, whereby live specimens contained much smaller amounts of this metalloid than was the case for Nonliving Material (2.4 and 20.3 mg kg−1, respectively). Experimental tests confirmed the ability of C. panizzoi detritus to retain arsenic at pH intervals and ionic strength characteristic of seawater. There are two potential sources of that metalloid for calcareous debris in sediments: brown macroalgae, which were found to contain high levels of As (up to 66.3 mg kg−1), and ferruginized sandstones (up to 23.0 mg kg−1). We argue that any contribution of brown algae to beach sediment enrichment by As would be minor, and consider the ferrous sandstones from coastal sedimentary rocks of the Barreiras Group as the principal large-scale source of arsenic in the marine environment of Espirito Santo. The experimental data, together with field studies, corroborate the interpretation that arsenic anomalies in sediments with calcareous debris can form when weathered continental rocks even only slightly enriched in As are leached by marine waters, and the As is at least partially retained by biogenic calcareous detritus in nearshore sediments. Considering that rocks of the Barreiras Group are exposed to marine erosion far to the north of Espirito Santo, we estimate that marine sediments containing calcareous Material are “anomalously” enriched in As along approximately 2,000 km of the Brazilian tropical coastline.
