The Experts below are selected from a list of 66 Experts worldwide ranked by ideXlab platform
Chiahung Kao - One of the best experts on this subject based on the ideXlab platform.
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Rheumatoid Arthritis Increases the Risk of Nontuberculosis Mycobacterial Disease and Active Pulmonary Tuberculosis
2016Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Chiahung KaoAbstract:Background: Few studies have examined the association of rheumatoid arthritis (RA) with Nontuberculosis Mycobacterium (NTM) disease and pulmonary tuberculosis (PTB). Methods:We identified 29 131 patients with RA from the catastrophic illness registry who were diagnosed from 1998–2008; 116 524 patients without RA from inpatient data files were randomly frequency matched according to sex, age, and index year and used as a comparison group. Both groups were followed-up until the end of 2010 to measure the incidence of NTM disease and active PTB. We analyzed the risk of NTM disease and active PTB using the Cox proportional hazards regression models, controlling for sex, age, and Charlson comorbidity index (CCI). Results: The incidence of NTM disease was 4.22 times greater in the RA group than in the non-RA group (1.91 vs 0.45 per 10,000 person-years). The incidence of PTB was 2.99 times greater in the RA group than in the non-RA group (25.3 vs 8.46 per 10,000 person-years). After adjusting for age, sex, and CCI, the adjusted hazard ratios (HRs) of NTM disease and active PTB for the RA group were 4.17 (95 % CI = 2.61–6.65) and 2.87 (95 % CI = 2.55–3.23), respectively, compared with the non-RA group. In the first 2 years of follow-up, the RA group yielded corresponding adjusted HRs of 4.98 and 3.39 compared with the non-RA group. The follow-up time-specific RA group to the non-RA group HR of both the NTM disease and active PTB varied
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Nontuberculosis Mycobacterium Disease is a Risk Factor for Chronic Obstructive Pulmonary Disease: A Nationwide Cohort Study
Lung, 2014Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Christine Yiting Chou, Chiahung KaoAbstract:Background The aim of this study was to evaluate the association between chronic obstructive pulmonary disease (COPD) and Nontuberculosis Mycobacterium (NTM) disease. Methods We used data from the National Health Insurance Research Database of Taiwan in this study. The NTM cohort contained 3,005 patients, and each case was randomly frequency matched by age, sex, income, occupation, and index year with four people from the general population without NTM infections. Multivariate Cox proportional hazards regression was used to calculate adjusted hazard ratios (aHR) of COPD in the NTM cohort compared with the non-NTM cohort. Results The incidence of COPD was 3.08-fold higher (21.75 vs. 6.11 per 1,000 person-years) in the NTM cohort than in the non-NTM cohort. The aHR of COPD comparing the NTM cohort with the non-NTM cohort was 3.57 (95 % CI 2.56–4.97) for women and 2.89 (95 % CI 2.31–3.61) for men. The aHR of COPD was higher in the patients with NTM infection and a comorbidity such as bronchopneumonia, pneumonia, diabetes, asthma, and heart disease. The Mycobacterium avium - intracellulare complex group (MAC) and the non-MAC group were isolated in the NTM cohort. The MAC group had a higher aHR of COPD than the non-NTM cohort (aHR = 3.72, 95 % CI 2.94–4.72). The cumulative incidence of COPD in the NTM cohort was higher than in the non-NTM cohort ( P
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Nontuberculosis Mycobacterium disease is a risk factor for chronic obstructive pulmonary disease a nationwide cohort study
Lung, 2014Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Christine Yiting Chou, Chiahung KaoAbstract:Background The aim of this study was to evaluate the association between chronic obstructive pulmonary disease (COPD) and Nontuberculosis Mycobacterium (NTM) disease.
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Rheumatoid arthritis increases the risk of Nontuberculosis mycobacterial disease and active pulmonary tuberculosis.
Public Library of Science (PLoS), 1Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Chiahung KaoAbstract:BACKGROUND: Few studies have examined the association of rheumatoid arthritis (RA) with Nontuberculosis Mycobacterium (NTM) disease and pulmonary tuberculosis (PTB). METHODS: We identified 29 131 patients with RA from the catastrophic illness registry who were diagnosed from 1998-2008; 116 524 patients without RA from inpatient data files were randomly frequency matched according to sex, age, and index year and used as a comparison group. Both groups were followed-up until the end of 2010 to measure the incidence of NTM disease and active PTB. We analyzed the risk of NTM disease and active PTB using the Cox proportional hazards regression models, controlling for sex, age, and Charlson comorbidity index (CCI). RESULTS: The incidence of NTM disease was 4.22 times greater in the RA group than in the non-RA group (1.91 vs 0.45 per 10,000 person-years). The incidence of PTB was 2.99 times greater in the RA group than in the non-RA group (25.3 vs 8.46 per 10,000 person-years). After adjusting for age, sex, and CCI, the adjusted hazard ratios (HRs) of NTM disease and active PTB for the RA group were 4.17 (95% CI = 2.61-6.65) and 2.87 (95% CI = 2.55-3.23), respectively, compared with the non-RA group. In the first 2 years of follow-up, the RA group yielded corresponding adjusted HRs of 4.98 and 3.39 compared with the non-RA group. The follow-up time-specific RA group to the non-RA group HR of both the NTM disease and active PTB varied. CONCLUSION: This study can serve as a reference for clinical physicians to increase awareness regarding the detection of NTM disease and active PTB in RA patients among the any stage of the clinical course even without CCI
Junjun Yeh - One of the best experts on this subject based on the ideXlab platform.
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Rheumatoid Arthritis Increases the Risk of Nontuberculosis Mycobacterial Disease and Active Pulmonary Tuberculosis
2016Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Chiahung KaoAbstract:Background: Few studies have examined the association of rheumatoid arthritis (RA) with Nontuberculosis Mycobacterium (NTM) disease and pulmonary tuberculosis (PTB). Methods:We identified 29 131 patients with RA from the catastrophic illness registry who were diagnosed from 1998–2008; 116 524 patients without RA from inpatient data files were randomly frequency matched according to sex, age, and index year and used as a comparison group. Both groups were followed-up until the end of 2010 to measure the incidence of NTM disease and active PTB. We analyzed the risk of NTM disease and active PTB using the Cox proportional hazards regression models, controlling for sex, age, and Charlson comorbidity index (CCI). Results: The incidence of NTM disease was 4.22 times greater in the RA group than in the non-RA group (1.91 vs 0.45 per 10,000 person-years). The incidence of PTB was 2.99 times greater in the RA group than in the non-RA group (25.3 vs 8.46 per 10,000 person-years). After adjusting for age, sex, and CCI, the adjusted hazard ratios (HRs) of NTM disease and active PTB for the RA group were 4.17 (95 % CI = 2.61–6.65) and 2.87 (95 % CI = 2.55–3.23), respectively, compared with the non-RA group. In the first 2 years of follow-up, the RA group yielded corresponding adjusted HRs of 4.98 and 3.39 compared with the non-RA group. The follow-up time-specific RA group to the non-RA group HR of both the NTM disease and active PTB varied
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Nontuberculosis Mycobacterium Disease is a Risk Factor for Chronic Obstructive Pulmonary Disease: A Nationwide Cohort Study
Lung, 2014Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Christine Yiting Chou, Chiahung KaoAbstract:Background The aim of this study was to evaluate the association between chronic obstructive pulmonary disease (COPD) and Nontuberculosis Mycobacterium (NTM) disease. Methods We used data from the National Health Insurance Research Database of Taiwan in this study. The NTM cohort contained 3,005 patients, and each case was randomly frequency matched by age, sex, income, occupation, and index year with four people from the general population without NTM infections. Multivariate Cox proportional hazards regression was used to calculate adjusted hazard ratios (aHR) of COPD in the NTM cohort compared with the non-NTM cohort. Results The incidence of COPD was 3.08-fold higher (21.75 vs. 6.11 per 1,000 person-years) in the NTM cohort than in the non-NTM cohort. The aHR of COPD comparing the NTM cohort with the non-NTM cohort was 3.57 (95 % CI 2.56–4.97) for women and 2.89 (95 % CI 2.31–3.61) for men. The aHR of COPD was higher in the patients with NTM infection and a comorbidity such as bronchopneumonia, pneumonia, diabetes, asthma, and heart disease. The Mycobacterium avium - intracellulare complex group (MAC) and the non-MAC group were isolated in the NTM cohort. The MAC group had a higher aHR of COPD than the non-NTM cohort (aHR = 3.72, 95 % CI 2.94–4.72). The cumulative incidence of COPD in the NTM cohort was higher than in the non-NTM cohort ( P
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Nontuberculosis Mycobacterium disease is a risk factor for chronic obstructive pulmonary disease a nationwide cohort study
Lung, 2014Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Christine Yiting Chou, Chiahung KaoAbstract:Background The aim of this study was to evaluate the association between chronic obstructive pulmonary disease (COPD) and Nontuberculosis Mycobacterium (NTM) disease.
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Rheumatoid arthritis increases the risk of Nontuberculosis mycobacterial disease and active pulmonary tuberculosis.
Public Library of Science (PLoS), 1Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Chiahung KaoAbstract:BACKGROUND: Few studies have examined the association of rheumatoid arthritis (RA) with Nontuberculosis Mycobacterium (NTM) disease and pulmonary tuberculosis (PTB). METHODS: We identified 29 131 patients with RA from the catastrophic illness registry who were diagnosed from 1998-2008; 116 524 patients without RA from inpatient data files were randomly frequency matched according to sex, age, and index year and used as a comparison group. Both groups were followed-up until the end of 2010 to measure the incidence of NTM disease and active PTB. We analyzed the risk of NTM disease and active PTB using the Cox proportional hazards regression models, controlling for sex, age, and Charlson comorbidity index (CCI). RESULTS: The incidence of NTM disease was 4.22 times greater in the RA group than in the non-RA group (1.91 vs 0.45 per 10,000 person-years). The incidence of PTB was 2.99 times greater in the RA group than in the non-RA group (25.3 vs 8.46 per 10,000 person-years). After adjusting for age, sex, and CCI, the adjusted hazard ratios (HRs) of NTM disease and active PTB for the RA group were 4.17 (95% CI = 2.61-6.65) and 2.87 (95% CI = 2.55-3.23), respectively, compared with the non-RA group. In the first 2 years of follow-up, the RA group yielded corresponding adjusted HRs of 4.98 and 3.39 compared with the non-RA group. The follow-up time-specific RA group to the non-RA group HR of both the NTM disease and active PTB varied. CONCLUSION: This study can serve as a reference for clinical physicians to increase awareness regarding the detection of NTM disease and active PTB in RA patients among the any stage of the clinical course even without CCI
Yuchiao Wang - One of the best experts on this subject based on the ideXlab platform.
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Rheumatoid Arthritis Increases the Risk of Nontuberculosis Mycobacterial Disease and Active Pulmonary Tuberculosis
2016Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Chiahung KaoAbstract:Background: Few studies have examined the association of rheumatoid arthritis (RA) with Nontuberculosis Mycobacterium (NTM) disease and pulmonary tuberculosis (PTB). Methods:We identified 29 131 patients with RA from the catastrophic illness registry who were diagnosed from 1998–2008; 116 524 patients without RA from inpatient data files were randomly frequency matched according to sex, age, and index year and used as a comparison group. Both groups were followed-up until the end of 2010 to measure the incidence of NTM disease and active PTB. We analyzed the risk of NTM disease and active PTB using the Cox proportional hazards regression models, controlling for sex, age, and Charlson comorbidity index (CCI). Results: The incidence of NTM disease was 4.22 times greater in the RA group than in the non-RA group (1.91 vs 0.45 per 10,000 person-years). The incidence of PTB was 2.99 times greater in the RA group than in the non-RA group (25.3 vs 8.46 per 10,000 person-years). After adjusting for age, sex, and CCI, the adjusted hazard ratios (HRs) of NTM disease and active PTB for the RA group were 4.17 (95 % CI = 2.61–6.65) and 2.87 (95 % CI = 2.55–3.23), respectively, compared with the non-RA group. In the first 2 years of follow-up, the RA group yielded corresponding adjusted HRs of 4.98 and 3.39 compared with the non-RA group. The follow-up time-specific RA group to the non-RA group HR of both the NTM disease and active PTB varied
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Nontuberculosis Mycobacterium Disease is a Risk Factor for Chronic Obstructive Pulmonary Disease: A Nationwide Cohort Study
Lung, 2014Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Christine Yiting Chou, Chiahung KaoAbstract:Background The aim of this study was to evaluate the association between chronic obstructive pulmonary disease (COPD) and Nontuberculosis Mycobacterium (NTM) disease. Methods We used data from the National Health Insurance Research Database of Taiwan in this study. The NTM cohort contained 3,005 patients, and each case was randomly frequency matched by age, sex, income, occupation, and index year with four people from the general population without NTM infections. Multivariate Cox proportional hazards regression was used to calculate adjusted hazard ratios (aHR) of COPD in the NTM cohort compared with the non-NTM cohort. Results The incidence of COPD was 3.08-fold higher (21.75 vs. 6.11 per 1,000 person-years) in the NTM cohort than in the non-NTM cohort. The aHR of COPD comparing the NTM cohort with the non-NTM cohort was 3.57 (95 % CI 2.56–4.97) for women and 2.89 (95 % CI 2.31–3.61) for men. The aHR of COPD was higher in the patients with NTM infection and a comorbidity such as bronchopneumonia, pneumonia, diabetes, asthma, and heart disease. The Mycobacterium avium - intracellulare complex group (MAC) and the non-MAC group were isolated in the NTM cohort. The MAC group had a higher aHR of COPD than the non-NTM cohort (aHR = 3.72, 95 % CI 2.94–4.72). The cumulative incidence of COPD in the NTM cohort was higher than in the non-NTM cohort ( P
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Nontuberculosis Mycobacterium disease is a risk factor for chronic obstructive pulmonary disease a nationwide cohort study
Lung, 2014Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Christine Yiting Chou, Chiahung KaoAbstract:Background The aim of this study was to evaluate the association between chronic obstructive pulmonary disease (COPD) and Nontuberculosis Mycobacterium (NTM) disease.
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Rheumatoid arthritis increases the risk of Nontuberculosis mycobacterial disease and active pulmonary tuberculosis.
Public Library of Science (PLoS), 1Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Chiahung KaoAbstract:BACKGROUND: Few studies have examined the association of rheumatoid arthritis (RA) with Nontuberculosis Mycobacterium (NTM) disease and pulmonary tuberculosis (PTB). METHODS: We identified 29 131 patients with RA from the catastrophic illness registry who were diagnosed from 1998-2008; 116 524 patients without RA from inpatient data files were randomly frequency matched according to sex, age, and index year and used as a comparison group. Both groups were followed-up until the end of 2010 to measure the incidence of NTM disease and active PTB. We analyzed the risk of NTM disease and active PTB using the Cox proportional hazards regression models, controlling for sex, age, and Charlson comorbidity index (CCI). RESULTS: The incidence of NTM disease was 4.22 times greater in the RA group than in the non-RA group (1.91 vs 0.45 per 10,000 person-years). The incidence of PTB was 2.99 times greater in the RA group than in the non-RA group (25.3 vs 8.46 per 10,000 person-years). After adjusting for age, sex, and CCI, the adjusted hazard ratios (HRs) of NTM disease and active PTB for the RA group were 4.17 (95% CI = 2.61-6.65) and 2.87 (95% CI = 2.55-3.23), respectively, compared with the non-RA group. In the first 2 years of follow-up, the RA group yielded corresponding adjusted HRs of 4.98 and 3.39 compared with the non-RA group. The follow-up time-specific RA group to the non-RA group HR of both the NTM disease and active PTB varied. CONCLUSION: This study can serve as a reference for clinical physicians to increase awareness regarding the detection of NTM disease and active PTB in RA patients among the any stage of the clinical course even without CCI
Fungchang Sung - One of the best experts on this subject based on the ideXlab platform.
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Rheumatoid Arthritis Increases the Risk of Nontuberculosis Mycobacterial Disease and Active Pulmonary Tuberculosis
2016Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Chiahung KaoAbstract:Background: Few studies have examined the association of rheumatoid arthritis (RA) with Nontuberculosis Mycobacterium (NTM) disease and pulmonary tuberculosis (PTB). Methods:We identified 29 131 patients with RA from the catastrophic illness registry who were diagnosed from 1998–2008; 116 524 patients without RA from inpatient data files were randomly frequency matched according to sex, age, and index year and used as a comparison group. Both groups were followed-up until the end of 2010 to measure the incidence of NTM disease and active PTB. We analyzed the risk of NTM disease and active PTB using the Cox proportional hazards regression models, controlling for sex, age, and Charlson comorbidity index (CCI). Results: The incidence of NTM disease was 4.22 times greater in the RA group than in the non-RA group (1.91 vs 0.45 per 10,000 person-years). The incidence of PTB was 2.99 times greater in the RA group than in the non-RA group (25.3 vs 8.46 per 10,000 person-years). After adjusting for age, sex, and CCI, the adjusted hazard ratios (HRs) of NTM disease and active PTB for the RA group were 4.17 (95 % CI = 2.61–6.65) and 2.87 (95 % CI = 2.55–3.23), respectively, compared with the non-RA group. In the first 2 years of follow-up, the RA group yielded corresponding adjusted HRs of 4.98 and 3.39 compared with the non-RA group. The follow-up time-specific RA group to the non-RA group HR of both the NTM disease and active PTB varied
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Nontuberculosis Mycobacterium Disease is a Risk Factor for Chronic Obstructive Pulmonary Disease: A Nationwide Cohort Study
Lung, 2014Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Christine Yiting Chou, Chiahung KaoAbstract:Background The aim of this study was to evaluate the association between chronic obstructive pulmonary disease (COPD) and Nontuberculosis Mycobacterium (NTM) disease. Methods We used data from the National Health Insurance Research Database of Taiwan in this study. The NTM cohort contained 3,005 patients, and each case was randomly frequency matched by age, sex, income, occupation, and index year with four people from the general population without NTM infections. Multivariate Cox proportional hazards regression was used to calculate adjusted hazard ratios (aHR) of COPD in the NTM cohort compared with the non-NTM cohort. Results The incidence of COPD was 3.08-fold higher (21.75 vs. 6.11 per 1,000 person-years) in the NTM cohort than in the non-NTM cohort. The aHR of COPD comparing the NTM cohort with the non-NTM cohort was 3.57 (95 % CI 2.56–4.97) for women and 2.89 (95 % CI 2.31–3.61) for men. The aHR of COPD was higher in the patients with NTM infection and a comorbidity such as bronchopneumonia, pneumonia, diabetes, asthma, and heart disease. The Mycobacterium avium - intracellulare complex group (MAC) and the non-MAC group were isolated in the NTM cohort. The MAC group had a higher aHR of COPD than the non-NTM cohort (aHR = 3.72, 95 % CI 2.94–4.72). The cumulative incidence of COPD in the NTM cohort was higher than in the non-NTM cohort ( P
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Nontuberculosis Mycobacterium disease is a risk factor for chronic obstructive pulmonary disease a nationwide cohort study
Lung, 2014Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Christine Yiting Chou, Chiahung KaoAbstract:Background The aim of this study was to evaluate the association between chronic obstructive pulmonary disease (COPD) and Nontuberculosis Mycobacterium (NTM) disease.
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Rheumatoid arthritis increases the risk of Nontuberculosis mycobacterial disease and active pulmonary tuberculosis.
Public Library of Science (PLoS), 1Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Chiahung KaoAbstract:BACKGROUND: Few studies have examined the association of rheumatoid arthritis (RA) with Nontuberculosis Mycobacterium (NTM) disease and pulmonary tuberculosis (PTB). METHODS: We identified 29 131 patients with RA from the catastrophic illness registry who were diagnosed from 1998-2008; 116 524 patients without RA from inpatient data files were randomly frequency matched according to sex, age, and index year and used as a comparison group. Both groups were followed-up until the end of 2010 to measure the incidence of NTM disease and active PTB. We analyzed the risk of NTM disease and active PTB using the Cox proportional hazards regression models, controlling for sex, age, and Charlson comorbidity index (CCI). RESULTS: The incidence of NTM disease was 4.22 times greater in the RA group than in the non-RA group (1.91 vs 0.45 per 10,000 person-years). The incidence of PTB was 2.99 times greater in the RA group than in the non-RA group (25.3 vs 8.46 per 10,000 person-years). After adjusting for age, sex, and CCI, the adjusted hazard ratios (HRs) of NTM disease and active PTB for the RA group were 4.17 (95% CI = 2.61-6.65) and 2.87 (95% CI = 2.55-3.23), respectively, compared with the non-RA group. In the first 2 years of follow-up, the RA group yielded corresponding adjusted HRs of 4.98 and 3.39 compared with the non-RA group. The follow-up time-specific RA group to the non-RA group HR of both the NTM disease and active PTB varied. CONCLUSION: This study can serve as a reference for clinical physicians to increase awareness regarding the detection of NTM disease and active PTB in RA patients among the any stage of the clinical course even without CCI
Christine Yiting Chou - One of the best experts on this subject based on the ideXlab platform.
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Nontuberculosis Mycobacterium Disease is a Risk Factor for Chronic Obstructive Pulmonary Disease: A Nationwide Cohort Study
Lung, 2014Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Christine Yiting Chou, Chiahung KaoAbstract:Background The aim of this study was to evaluate the association between chronic obstructive pulmonary disease (COPD) and Nontuberculosis Mycobacterium (NTM) disease. Methods We used data from the National Health Insurance Research Database of Taiwan in this study. The NTM cohort contained 3,005 patients, and each case was randomly frequency matched by age, sex, income, occupation, and index year with four people from the general population without NTM infections. Multivariate Cox proportional hazards regression was used to calculate adjusted hazard ratios (aHR) of COPD in the NTM cohort compared with the non-NTM cohort. Results The incidence of COPD was 3.08-fold higher (21.75 vs. 6.11 per 1,000 person-years) in the NTM cohort than in the non-NTM cohort. The aHR of COPD comparing the NTM cohort with the non-NTM cohort was 3.57 (95 % CI 2.56–4.97) for women and 2.89 (95 % CI 2.31–3.61) for men. The aHR of COPD was higher in the patients with NTM infection and a comorbidity such as bronchopneumonia, pneumonia, diabetes, asthma, and heart disease. The Mycobacterium avium - intracellulare complex group (MAC) and the non-MAC group were isolated in the NTM cohort. The MAC group had a higher aHR of COPD than the non-NTM cohort (aHR = 3.72, 95 % CI 2.94–4.72). The cumulative incidence of COPD in the NTM cohort was higher than in the non-NTM cohort ( P
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Nontuberculosis Mycobacterium disease is a risk factor for chronic obstructive pulmonary disease a nationwide cohort study
Lung, 2014Co-Authors: Junjun Yeh, Yuchiao Wang, Fungchang Sung, Christine Yiting Chou, Chiahung KaoAbstract:Background The aim of this study was to evaluate the association between chronic obstructive pulmonary disease (COPD) and Nontuberculosis Mycobacterium (NTM) disease.
