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Pietro Sampaio Baruselli - One of the best experts on this subject based on the ideXlab platform.
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the use of estradiol valerate or benzoate at the beginning of the ftai protocol results in similar pregnancy rate in suckled nelore bos indicus cows regardless of progesterone progestin source
Animal reproduction, 2014Co-Authors: R P Martins, M Sa F Filho, L M Vieira, L Penteado, L Graeff, B G Freitas, Pietro Sampaio BaruselliAbstract:The present study aimed to evaluate the efficiency of different estradiol esters (estradiol valerate, EV or benzoate, EB) and different progesterone/progestin sources [intravaginal progesterone (DIB, P4) device and Norgestomet ear implant (Crestar)] in multiparous Nelore (Bos indicus) cows with 3.3 ± 0.0 of BCS and 30 to 60 days postpartum, at the beginning of the fixed-time artificial insemination (FTAI) protocol. A total of 501 females was allocated into four different experimental groups: 1. EV+DIB (n = 117) – on a random day of the estrus cycle (Day -1), intramuscular (IM) injection of 5.0 mg of EV (Injectable solution of the Crestar®, MSD Animal Health, Sao Paulo, Brazil) and insertion of an intravaginal P4 device (DIB®, MSD Animal Health, Sao Paulo, Brazil). On Day 8, the P4 device was removed and 300 IU of equine chorionic gonadotropin (eCG; Folligon®, MSD Animal Health, Sao Paulo, Brazil) was administrated IM; 2. EV+CRESTAR (n = 130) – the animals were submitted to the same protocol of group EV+DIB, however using the Norgestomet ear implant (Crestar®, MSD Animal Health, Sao Paulo, Brazil) instead of the P4 device; 3. EB+DIB (n = 122) – on a random day of the estrus cycle (day 0), IM injection of 2.0 mg of EB (Gonadiol®, MSD Animal Health, Sao Paulo, Brazil) and insertion of a P4 device. On Day 8, the P4 device was removed and 300 IU of eCG were administrated IM; 4. EB+CRESTAR (n = 132) the animals were submitted to the same protocol of group EB+DIB, however using Norgestomet ear implant instead of the P4 device. Additionally, animals in groups 3 and 4 were treated with 1.0 mg IM of estradiol cypionate (EC, E.C.P®, Zoetis, Sao Paulo, Brazil) and 150 µg IM of D-cloprostenol (PGF; Preloban®, MSD Animal Health, Sao Paulo, Brazil) on Day 8 (as revised by Baruselli et al., Animal Reproduction, v.9, p.139-152, 2012). All females were timed artificially inseminated 48h after the device/implant removal (Day 10) and submitted to ultrasound evaluation (Aloka SSD 500, Aloka, Japan) for pregnancy diagnosis 30 d after FTAI. All data were analyzed by the GLIMMIX procedure of SAS 9.3. There was no interaction (P = 0.48) between the different estradiol esters (EV vs. EB) and the different sources of P4/progestin (DIB vs. CRESTAR). Therefore, as main effects, it was observed similar pregnancy rates regarding the two estradiol esters [EB = 58.3% (148/254) vs. EV = 53.9% (133/247); P = 0.29] and the different sources of P4/progestin [DIB = 56.1% (134/239) vs. CRESTAR = 56.1% (147/262); P = 0.97]. In conclusion, both estradiol esters (EV and EB) associated with either DIB or Crestar resulted in similar pregnancy rate after FTAI protocol in multiparous Nelore cows.
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the effect of timing of the induction of ovulation on embryo production in superstimulated lactating holstein cows undergoing fixed time artificial insemination
Theriogenology, 2012Co-Authors: C M Martins, C A Rodrigues, M Sa F Filho, L M Vieira, R J Mapletoft, Pietro Sampaio BaruselliAbstract:Two experiments evaluated the effects of timing of the induction of ovulation in superstimulated lactating Holstein donor cows that were fixed-time artificially inseminated. Secondary objectives were to evaluate the effects of the timing of progesterone (P4) device removal (Experiment 1) or the addition of a second Norgestomet implant (Experiment 2) during superstimulation. In Experiment 1, 12 cows were allocated to one of four treatment groups with the timing of P4 device removal (24 or 36 h) and pLH treatment (48 or 60 h), after the first PGF as main factors, in a Latin Square (cross-over) design. There was an interaction (P = 0.03) between time of P4 device removal and time of pLH treatment. Mean (± SEM) numbers of transferable embryos were higher when the P4 device was removed at 36 h and pLH was administered at 60 h after the first PGF (P36LH60 =6.3 ± 1.4) compared to other treatments (P24LH60 =3.7 ± 1.1; P24LH48 =2.4 ± 0.8; or P36LH48 =2.2 ± 0.7). In Experiment 2, 40 cows were randomly allocated into one of four treatments with the number of Norgestomet implants (one or two) and the time of induction of ovulation with GnRH relative to the first PGF (48 vs. 60 h) as main effects. The mean number of transferable embryos was higher (P = 0.02) when GnRH was administered at 60 h (4.2 ± 1.3) compared to at 48 h (2.7 ± 0.8), and the number of freezable embryos was increased (P = 0.01) in cows receiving two (3.0 ± 1.0) rather than one Norgestomet implant (1.5 ± 0.5). In summary, embryo production in lactating Holstein cows was increased when the ovulatory stimulus (pLH or GnRH) was given 60 h after the first PGF, particularly when the P4 device was removed 36 h after the first PGF and when two Norgestomet ear implants were used during the superstimulation protocol.
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equine chorionic gonadotropin improves the efficacy of a progestin based fixed time artificial insemination protocol in nelore bos indicus heifers
Animal Reproduction Science, 2010Co-Authors: M Sa F Filho, H Ayres, R M Ferreira, L Penteado, J R S Torresjunior, L U Gimenes, L Castro A E Paula, J N S Sales, Pietro Sampaio BaruselliAbstract:Abstract A total of 177 Nelore heifers were examined by ultrasonography to determine the presence or absence of a corpus luteum (CL) and received a 3 mg Norgestomet ear implant plus 2 mg of estradiol benzoate i.m. On Day 8, implants were removed and 150 μg of d -cloprostenol i.m. was administered. At the time of Norgestomet implant removal, heifers with or without CL at the time of initiating treatment were assigned equally and by replicate to be treated with 0 IU ( n = 87) or 400 IU ( n = 90) eCG i.m. All heifers received 1 mg of EB i.m. on Day 9 and were submitted to fixed-time artificial insemination (FTAI) 30–34 h later. The addition of eCG increased the diameter of the largest follicle (LF) at FTAI (10.6 ± 0.2 mm vs. 9.5 ± 0.2 mm; P = 0.003; mean ± SEM), the final growth rate of the LF (1.14 ± 0.1 mm/day vs. 0.64 ± 0.1 mm/day; P = 0.0009), ovulation rate [94.4% (85/90) vs. 73.6% (64/87); P = 0.0006], the diameter of the CL at Day 15 (15.5 ± 0.3 mm vs. 13.8 ± 0.3 mm; P = 0.0002), serum concentrations of progesterone 5 days after FTAI (6.6 ± 1.0 ng/ml vs. 3.6 ± 0.7 ng/ml; P = 0.0009), and pregnancy per AI [P/AI; 50.0% (45/90) vs. 36.8% (32/87); P = 0.04]. The absence of a CL at the beginning of the treatment negatively influenced the P/AI [30.2% (16/53) vs. 49.2% (61/124); P = 0.01]. Therefore, the presence of a CL (and/or onset of puberty) must be considered in setting up FTAI programs in heifers. In addition, eCG may be an important tool for the enhancement of follicular growth, ovulation, size and function of the subsequent CL, and pregnancy rates in progestin-based FTAI protocols in Bos indicus heifers.
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equine chorionic gonadotropin and gonadotropin releasing hormone enhance fertility in a Norgestomet based timed artificial insemination protocol in suckled nelore bos indicus cows
Theriogenology, 2010Co-Authors: M Sa F Filho, R. C. P. Silva, H Ayres, R M Ferreira, M O Marques, E L Reis, C A Rodrigues, E H Madureira, G. A. Bó, Pietro Sampaio BaruselliAbstract:Two experiments were conducted to investigate the effects of equine chorionic gonadotropin (eCG) at progestin removal and gonadotropin-releasing hormone (GnRH) at timed artificial insemination (TAI) on ovarian follicular dynamics (Experiment 1) and pregnancy rates (Experiment 2) in suckled Nelore (Bos indicus) cows. Both experiments were 2 × 2 factorials (eCG or No eCG, and GnRH or No GnRH), with identical treatments. In Experiment 1, 50 anestrous cows, 134.5 ± 2.3 d postpartum, received a 3 mg Norgestomet ear implant sc, plus 3 mg Norgestomet and 5 mg estradiol valerate im on Day 0. The implant was removed on Day 9, with TAI 54 h later. Cows received 400 IU eCG or no further treatment on Day 9 and GnRH (100 μg gonadorelin) or no further treatment at TAI. Treatment with eCG increased the growth rate of the largest follicle from Days 9 to 11 (means ± SEM, 1.53 ± 0.1 vs. 0.48 ± 0.1 mm/d; P < 0.0001), its diameter on Day 11 (11.4 ± 0.6 vs. 9.3 ± 0.7 mm; P = 0.03), as well as ovulation rate (80.8% vs. 50.0%, P = 0.02), whereas GnRH improved the synchrony of ovulation (72.0 ± 1.1 vs. 71.1 ± 2.0 h). In Experiment 2 (n = 599 cows, 40 to 120 d postpartum), pregnancy rates differed (P = 0.004) among groups (27.6%, 40.1%, 47.7%, and 55.7% for Control, GnRH, eCG, and eCG + GnRH groups). Both eCG and GnRH improved pregnancy rates (51.7% vs. 33.8%, P = 0.002; and 48.0% vs 37.6%, P = 0.02, respectively), although their effects were not additive (no significant interaction). In conclusion, eCG at Norgestomet implant removal increased the growth rate of the largest follicle (LF) from implant removal to TAI, the diameter of the LF at TAI, and rates of ovulation and pregnancy rates. Furthermore, GnRH at TAI improved the synchrony of ovulations and pregnancy rates in postpartum Nelore cows treated with a Norgestomet-based TAI protocol.
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Efeito do eCG ou benzoato de estradiol associado ao Norgestomet na taxa de concepção de vacas de corte submetidas à IATF no pós-parto
Universidade de São Paulo, 2009Co-Authors: Luis Augusto Ferreira Rossa, Pietro Sampaio Baruselli, Alexandre Barreto De ,almeida, Claudia Maria Bertan, Pércio Dos Santos Gaspar, Paulo Henrique Mazza, Mario Binelli, Ed Hoffmann MadureiraAbstract:Este estudo objetivou comparar as taxas de concepção, em vacas de corte no período pós-parto (PPP), tratadas com Gonadotrofina Coriônica Eqüina (eCG) ou Benzoato de Estradiol (BE), após o uso de Norgestomet submetidas à inseminação artificial em tempo fixo (IATF). A hipótese é que a administração de eCG ou BE aumenta as taxas de concepção. Vacas Nelore (n=138) e Brangus (n=63), lactantes, entre 26 e 118 dias do PPP, foram divididas em três grupos homogêneos e dentro de cada grupo subdivididas em dois blocos, um com um PPP < 45 dias (PPP1; n=107) e outro >; 45 dias (PPP2; n=94). Todas as fêmeas receberam um implante auricular contendo 3mg de Norgestomet (Crestar®), seguido pela administração de 5mg de Valerato de Estradiol. Os implantes auriculares foram mantidos durante 10 dias. Na retirada dos implantes, as fêmeas receberam 1mL de solução fisiológica (n=68; Grupo Controle) ou 500UI de eCG (Folligon®; n=67; Grupo eCG) ou 1mg de Benzoato de Estradiol (Index; n=66; Grupo BE) 24 horas após a retirada do implante. A IATF foi realizada 54 horas após a retirada do implante. O diagnóstico de gestação foi realizado por ultra-sonografia 30 dias após a IATF. Houve interação entre os tratamentos e o PPP. No PPP1, a taxa de concepção foi maior no grupo eCG comparado ao BE (47,22% vs. 15,38%; P
Alexandre Barreto De ,almeida - One of the best experts on this subject based on the ideXlab platform.
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Effect of eCG or estradiol benzoate associated with Norgestomet on the conception rate of beef cows submitted to FTAI in the postpartum
2009Co-Authors: Rossa, Luis Augusto Ferreira, Alexandre Barreto De ,almeida, Bertan, Claudia Maria, Gaspar, Pércio Dos Santos, Binelli Mario, Baruselli Pietro Sampaio, Rodrigues, Paulo Henrique Mazza, Madureira, Ed HoffmannAbstract:Este estudo objetivou comparar as taxas de concepção, em vacas de corte no período pós-parto (PPP), tratadas com Gonadotrofina Coriônica Eqüina (eCG) ou Benzoato de Estradiol (BE), após o uso de Norgestomet submetidas à inseminação artificial em tempo fixo (IATF). A hipótese é que a administração de eCG ou BE aumenta as taxas de concepção. Vacas Nelore (n=138) e Brangus (n=63), lactantes, entre 26 e 118 dias do PPP, foram divididas em três grupos homogêneos e dentro de cada grupo subdivididas em dois blocos, um com um PPP < 45 dias (PPP1; n=107) e outro > 45 dias (PPP2; n=94). Todas as fêmeas receberam um implante auricular contendo 3mg de Norgestomet (Crestar®), seguido pela administração de 5mg de Valerato de Estradiol. Os implantes auriculares foram mantidos durante 10 dias. Na retirada dos implantes, as fêmeas receberam 1mL de solução fisiológica (n=68; Grupo Controle) ou 500UI de eCG (Folligon®; n=67; Grupo eCG) ou 1mg de Benzoato de Estradiol (Index; n=66; Grupo BE) 24 horas após a retirada do implante. A IATF foi realizada 54 horas após a retirada do implante. O diagnóstico de gestação foi realizado por ultra-sonografia 30 dias após a IATF. Houve interação entre os tratamentos e o PPP. No PPP1, a taxa de concepção foi maior no grupo eCG comparado ao BE (47,22% vs. 15,38%; P
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Efeito do eCG ou benzoato de estradiol associado ao Norgestomet na taxa de concepção de vacas de corte submetidas à IATF no pós-parto
Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia, 2009Co-Authors: Rossa, Luis Augusto Ferreira, Alexandre Barreto De ,almeida, Bertan, Claudia Maria, Gaspar, Pércio Dos Santos, Mazza, Paulo Henrique, Binelli Mario, Baruselli Pietro Sampaio, Madureira, Ed HoffmannAbstract:This study aimed to compare conception rates at the postpartum period (PPP) in beef cows which were administered either Equine Chorionic Gonadotrophin (eCG) or Estradiol Benzoate (EB) after Norgestomet and submitted to fixed-time artificial insemination (FTAI). The hypothesis was that the administration of eCG or EB enhances the conception rate. Lactating Nelore cows (n=138) and Brangus (n = 63), between 26 and 118 days of post partum period (PPP) were divided into three homogeneous groups, and subdivided in two blocks, inside each group one of them with a PPP d" 45 days (PPP1; n=107) and another with a PPP >; 45 days (PPP2; n=94). All cows received an auricular implant containing 3mg Norgestomet (Crestar®), followed by the administration of 5mg Estradiol Valerate. The auricular implants were kept during 10 days. Cows received 1mL saline solution (n=68, Control Group) or 500IU eCG (Folligon®; n=67; eCG Group) or 1mg Estradiol Benzoate (Index, n=66; EB Group) 24 hours after the removal of the implant. FTAI was made 54 hours after the implant removal. The pregnancy diagnosis was carried through ultrasonography 30 days after FTAI. There was an interaction between treatments and PPP. In the PPP1, the conception rate was higher in the eCG Group than in the EB Group (47.22% vs. 15.38%; Pd"0.01). In the PPP2, the conception rates of the eCG and EB Groups were higher than in the Control Group (41.93%, 44.44% vs. 22.22%: Pd"0.01). It was concluded that in cows up to 45 days of PPP, the eCG associated with Norgestomet enhances the conception rates.Este estudo objetivou comparar as taxas de concepção, em vacas de corte no período pós-parto (PPP), tratadas com Gonadotrofina Coriônica Eqüina (eCG) ou Benzoato de Estradiol (BE), após o uso de Norgestomet submetidas à inseminação artificial em tempo fixo (IATF). A hipótese é que a administração de eCG ou BE aumenta as taxas de concepção. Vacas Nelore (n=138) e Brangus (n=63), lactantes, entre 26 e 118 dias do PPP, foram divididas em três grupos homogêneos e dentro de cada grupo subdivididas em dois blocos, um com um PPP < 45 dias (PPP1; n=107) e outro >; 45 dias (PPP2; n=94). Todas as fêmeas receberam um implante auricular contendo 3mg de Norgestomet (Crestar®), seguido pela administração de 5mg de Valerato de Estradiol. Os implantes auriculares foram mantidos durante 10 dias. Na retirada dos implantes, as fêmeas receberam 1mL de solução fisiológica (n=68; Grupo Controle) ou 500UI de eCG (Folligon®; n=67; Grupo eCG) ou 1mg de Benzoato de Estradiol (Index; n=66; Grupo BE) 24 horas após a retirada do implante. A IATF foi realizada 54 horas após a retirada do implante. O diagnóstico de gestação foi realizado por ultra-sonografia 30 dias após a IATF. Houve interação entre os tratamentos e o PPP. No PPP1, a taxa de concepção foi maior no grupo eCG comparado ao BE (47,22% vs. 15,38%; P<0,01). No PPP2, as taxas de concepção dos grupos eCG e BE foram maiores que no grupo controle (41,93%, 44,44% vs. 22,22%; P<0,01). Conclui-se que vacas, com até 45 dias do PPP, o eCG associado ao Norgestomet aumenta as taxas de concepção
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Efeito do eCG ou benzoato de estradiol associado ao Norgestomet na taxa de concepção de vacas de corte submetidas à IATF no pós-parto
Universidade de São Paulo, 2009Co-Authors: Luis Augusto Ferreira Rossa, Pietro Sampaio Baruselli, Alexandre Barreto De ,almeida, Claudia Maria Bertan, Pércio Dos Santos Gaspar, Paulo Henrique Mazza, Mario Binelli, Ed Hoffmann MadureiraAbstract:Este estudo objetivou comparar as taxas de concepção, em vacas de corte no período pós-parto (PPP), tratadas com Gonadotrofina Coriônica Eqüina (eCG) ou Benzoato de Estradiol (BE), após o uso de Norgestomet submetidas à inseminação artificial em tempo fixo (IATF). A hipótese é que a administração de eCG ou BE aumenta as taxas de concepção. Vacas Nelore (n=138) e Brangus (n=63), lactantes, entre 26 e 118 dias do PPP, foram divididas em três grupos homogêneos e dentro de cada grupo subdivididas em dois blocos, um com um PPP < 45 dias (PPP1; n=107) e outro >; 45 dias (PPP2; n=94). Todas as fêmeas receberam um implante auricular contendo 3mg de Norgestomet (Crestar®), seguido pela administração de 5mg de Valerato de Estradiol. Os implantes auriculares foram mantidos durante 10 dias. Na retirada dos implantes, as fêmeas receberam 1mL de solução fisiológica (n=68; Grupo Controle) ou 500UI de eCG (Folligon®; n=67; Grupo eCG) ou 1mg de Benzoato de Estradiol (Index; n=66; Grupo BE) 24 horas após a retirada do implante. A IATF foi realizada 54 horas após a retirada do implante. O diagnóstico de gestação foi realizado por ultra-sonografia 30 dias após a IATF. Houve interação entre os tratamentos e o PPP. No PPP1, a taxa de concepção foi maior no grupo eCG comparado ao BE (47,22% vs. 15,38%; P
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Used Norgestomet implants in Nelore cows
'Universidade de Sao Paulo Agencia USP de Gestao da Informacao Academica (AGUIA)', 2007Co-Authors: Alexandre Barreto De ,almeidaAbstract:Compararam-se as taxas de prenhez (TP) em vacas Nelore (Bos taurus indicus) utilizando implantes de Norgestomet novos ou reutilizados associados ao valerato de estradiol (VE) e benzoato de estradiol (BE). Duzentos e quarenta e uma vacas Nelore amamentando foram separadas em dois grupos, e receberam implante auricular contendo 3 mg de Norgestomet (n=122) ou implante de Norgestomet (n=119) que já havia sido previamente utilizado por 10 dias. Os animais que receberam implante novo ou reutilizado, foram sub-divididos, e um lote recebeu uma injeção (IM) de 3 mg de Norgestomet associados a 5 mg de valerato de estradiol e o outro, uma injeção (IM) de 50 mg de progesterona associados a 2 mg de benzoato de estradiol. No momento da retirada do implante todos os animais receberam 1 aplicação de análogo de PGF2α (IM) para assegurar a luteólise e 24 h após uma injeção de 1,0 mg de BE (IM). A inseminação artificial em tempo fixo (IATF) ocorreu 54-56 h após a retirada do implante. Não houve interação entre tipo de implante e tipo de éster de estradiol para TP IATF nem TP Final. As TP IATF não diferiram entre animais que receberam implante novo ou reutilizado (48,3 vs 48,7%) nem entre os que receberam VE ou BE (49,5 vs 47,5%). O mesmo ocorreu para TP Final segundo tipo de implante, novo ou reutilizado (85,2 vs 86,5%) e segundo tipo de éster de estradiol, VE ou BE (86,5 vs 85,2%). Conclui-se que vacas Nelore amamentando podem apresentar adequadas TP IATF e TP Final quando tratadas por implantes de Norgestomet novos ou reutilizados associados indistintamente ao valerato ou benzoato de estradiol.Pregnacy rates (PR) were compared in Nelore cows (Bos taurus indicus) using new or used Norgestomet implants associated to estradiol valerate (EV) and estradiol benzoate (EB). Two hundred forty one Nelore cows were synchronized and divided in two groups, they received auricular implants with 3 mg of Norgestomet (n=122) or used Norgestomet implants (n=119) previously used for 10 days. The animals that received new or used implants were sub-divided and received an administration (im) of 3 mg of Norgestomet plus 5 mg of EV and another group received an administration of 50 mg of progesterone plus 2 mg of EB. When the implant was removed a dose of PGF2α analogous was given for all animals to assure luteolysis and 24 h later they received (im) of 1,0 mg of EB. The fixed-timed artificial insemination (AIFT) occurred 54-56 h after implant withdrawal. There was no difference between the two implants as well as no diffrence to EV or EB, neither PR AITF nor PR Finish. The PR AIFT did not differ among animals that received that received new or used implants (48,3 vs 48,7%) neither EV nor EB (49,5 vs 47,5%). The same happened to PR Finish either new or used (85,2 vs 86,5%) when EV or EB (86,5 vs 85,2%) were used. In this present study, it was concluded that Nelore suckling cows can show a regulated PR AIFT and PR Finish after treatments with new or used Norgestomet implants associated to EV or EB
R. J. Favero - One of the best experts on this subject based on the ideXlab platform.
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Needleless Implant Delivery of Gonadotropin-Releasing Hormone Enhances the Calving Rate of Beef Cows Synchronized with Norgestomet and Estradiol Valerate*
Drug Development and Industrial Pharmacy, 2008Co-Authors: D J Kesler, R. J. FaveroAbstract:AbstractOne-hundred and six beef cows were included in a study to determine if gonadot-ropin-releasing hormone (GnRH) administered via needleless implants would enhance calving rate like conventional GnRH administration. All cows were synchronized with the Norgestomet and estradiol valerate estrus synchronization procedure and then randomly assigned to one of three groups: no GnRH, GnRH via conventional implants, and GnRH via needleless implants. GnRH was administered 30 hr after Norgestomet implant removal. Although needleless implants were administered while cows were restrained, they may be administered remotely. GnRH administered by both methods equally enhanced (p < 0.05) calving rate and the needleless implant caused minimal response by the cows. Therefore, remote administration of GnRH may accomplish therapeutic efficacy and reduce the time, labor, stress, and risk of injury associated with providing conventional animal therapy.
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a comparison of hydron and silicone implants in the bovine Norgestomet and estradiol valerate estrus synchronization procedure
Drug Development and Industrial Pharmacy, 1995Co-Authors: D J Kesler, R. J. Favero, T R TroxelAbstract:AbstractHydron and silicone implants impregnated with Norgestomet were used in the bovine Norgestomet and estradiol valerate estrus synchronization procedure. Total Norgestomet secreted from the implants over the 9 day implantation period was similar (P > .25) for both implants (both in vitro and in vivo) and was released in vitro in linear declining patterns but decreasing at different rates (slopes of -66.5 [hydron] and -22.1 [silicone] [both P .25) to total in vivo secretion over the 9 day period for both types of implants. On days 1 and 2, more (P < .01) Norgestomet was secreted from the hydron implants whereas on days 3 to 9 more (P < .01) Norgestomet was secreted from the silicone implants. In vivo efficacy data demonstrated that synchronized pregnancy rates were greater (44 % vs 53 %; P < .01) for cattle treated with the procedure utilizing the silicone implant.
Madureira, Ed Hoffmann - One of the best experts on this subject based on the ideXlab platform.
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Effect of eCG or estradiol benzoate associated with Norgestomet on the conception rate of beef cows submitted to FTAI in the postpartum
2009Co-Authors: Rossa, Luis Augusto Ferreira, Gaspar, Pércio Dos Santos, Mazza, Paulo Henrique, Binelli Mario, Baruselli Pietro Sampaio, Bertan, Claudia Maria [unesp], De Almeida, Alexandre Barreto, Madureira, Ed HoffmannAbstract:This study aimed to compare conception rates at the postpartum period (PPP) in beef cows which were administered either Equine Chorionic Gonadotrophin (eCG) or Estradiol Benzoate (EB) after Norgestomet and submitted to fixed-time artificial insemination (FTAI). The hypothesis was that the administration of eCG or EB enhances the conception rate. Lactating Nelore cows (n=138) and Brangus (n = 63), between 26 and 118 days of post partum period (PPP) were divided into three homogeneous groups, and subdivided in two blocks, inside each group one of them with a PPP d'' 45 days (PPP1; n=107) and another with a PPP > 45 days (PPP2; n=94). All cows received an auricular implant containing 3mg Norgestomet (Crestar®), followed by the administration of 5mg Estradiol Valerate. The auricular implants were kept during 10 days. Cows received 1mL saline solution (n=68, Control Group) or 500IU eCG (Folligon®; n=67; eCG Group) or 1mg Estradiol Benzoate (Index, n=66; EB Group) 24 hours after the removal of the implant. FTAI was made 54 hours after the implant removal. The pregnancy diagnosis was carried through ultrasonography 30 days after FTAI. There was an interaction between treatments and PPP. In the PPP1, the conception rate was higher in the eCG Group than in the EB Group (47.22% vs. 15.38%; Pd''0.01). In the PPP2, the conception rates of the eCG and EB Groups were higher than in the Control Group (41.93%, 44.44% vs. 22.22%: Pd''0.01). It was concluded that in cows up to 45 days of PPP, the eCG associated with Norgestomet enhances the conception rates
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Efeito do eCG ou benzoato de estradiol associado ao Norgestomet na taxa de concepção de vacas de corte submetidas à IATF no pós-parto
Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia, 2009Co-Authors: Rossa, Luis Augusto Ferreira, Alexandre Barreto De ,almeida, Bertan, Claudia Maria, Gaspar, Pércio Dos Santos, Mazza, Paulo Henrique, Binelli Mario, Baruselli Pietro Sampaio, Madureira, Ed HoffmannAbstract:This study aimed to compare conception rates at the postpartum period (PPP) in beef cows which were administered either Equine Chorionic Gonadotrophin (eCG) or Estradiol Benzoate (EB) after Norgestomet and submitted to fixed-time artificial insemination (FTAI). The hypothesis was that the administration of eCG or EB enhances the conception rate. Lactating Nelore cows (n=138) and Brangus (n = 63), between 26 and 118 days of post partum period (PPP) were divided into three homogeneous groups, and subdivided in two blocks, inside each group one of them with a PPP d" 45 days (PPP1; n=107) and another with a PPP >; 45 days (PPP2; n=94). All cows received an auricular implant containing 3mg Norgestomet (Crestar®), followed by the administration of 5mg Estradiol Valerate. The auricular implants were kept during 10 days. Cows received 1mL saline solution (n=68, Control Group) or 500IU eCG (Folligon®; n=67; eCG Group) or 1mg Estradiol Benzoate (Index, n=66; EB Group) 24 hours after the removal of the implant. FTAI was made 54 hours after the implant removal. The pregnancy diagnosis was carried through ultrasonography 30 days after FTAI. There was an interaction between treatments and PPP. In the PPP1, the conception rate was higher in the eCG Group than in the EB Group (47.22% vs. 15.38%; Pd"0.01). In the PPP2, the conception rates of the eCG and EB Groups were higher than in the Control Group (41.93%, 44.44% vs. 22.22%: Pd"0.01). It was concluded that in cows up to 45 days of PPP, the eCG associated with Norgestomet enhances the conception rates.Este estudo objetivou comparar as taxas de concepção, em vacas de corte no período pós-parto (PPP), tratadas com Gonadotrofina Coriônica Eqüina (eCG) ou Benzoato de Estradiol (BE), após o uso de Norgestomet submetidas à inseminação artificial em tempo fixo (IATF). A hipótese é que a administração de eCG ou BE aumenta as taxas de concepção. Vacas Nelore (n=138) e Brangus (n=63), lactantes, entre 26 e 118 dias do PPP, foram divididas em três grupos homogêneos e dentro de cada grupo subdivididas em dois blocos, um com um PPP < 45 dias (PPP1; n=107) e outro >; 45 dias (PPP2; n=94). Todas as fêmeas receberam um implante auricular contendo 3mg de Norgestomet (Crestar®), seguido pela administração de 5mg de Valerato de Estradiol. Os implantes auriculares foram mantidos durante 10 dias. Na retirada dos implantes, as fêmeas receberam 1mL de solução fisiológica (n=68; Grupo Controle) ou 500UI de eCG (Folligon®; n=67; Grupo eCG) ou 1mg de Benzoato de Estradiol (Index; n=66; Grupo BE) 24 horas após a retirada do implante. A IATF foi realizada 54 horas após a retirada do implante. O diagnóstico de gestação foi realizado por ultra-sonografia 30 dias após a IATF. Houve interação entre os tratamentos e o PPP. No PPP1, a taxa de concepção foi maior no grupo eCG comparado ao BE (47,22% vs. 15,38%; P<0,01). No PPP2, as taxas de concepção dos grupos eCG e BE foram maiores que no grupo controle (41,93%, 44,44% vs. 22,22%; P<0,01). Conclui-se que vacas, com até 45 dias do PPP, o eCG associado ao Norgestomet aumenta as taxas de concepção
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Effect of eCG or estradiol benzoate associated with Norgestomet on the conception rate of beef cows submitted to FTAI in the postpartum
2009Co-Authors: Rossa, Luis Augusto Ferreira, Alexandre Barreto De ,almeida, Bertan, Claudia Maria, Gaspar, Pércio Dos Santos, Binelli Mario, Baruselli Pietro Sampaio, Rodrigues, Paulo Henrique Mazza, Madureira, Ed HoffmannAbstract:Este estudo objetivou comparar as taxas de concepção, em vacas de corte no período pós-parto (PPP), tratadas com Gonadotrofina Coriônica Eqüina (eCG) ou Benzoato de Estradiol (BE), após o uso de Norgestomet submetidas à inseminação artificial em tempo fixo (IATF). A hipótese é que a administração de eCG ou BE aumenta as taxas de concepção. Vacas Nelore (n=138) e Brangus (n=63), lactantes, entre 26 e 118 dias do PPP, foram divididas em três grupos homogêneos e dentro de cada grupo subdivididas em dois blocos, um com um PPP < 45 dias (PPP1; n=107) e outro > 45 dias (PPP2; n=94). Todas as fêmeas receberam um implante auricular contendo 3mg de Norgestomet (Crestar®), seguido pela administração de 5mg de Valerato de Estradiol. Os implantes auriculares foram mantidos durante 10 dias. Na retirada dos implantes, as fêmeas receberam 1mL de solução fisiológica (n=68; Grupo Controle) ou 500UI de eCG (Folligon®; n=67; Grupo eCG) ou 1mg de Benzoato de Estradiol (Index; n=66; Grupo BE) 24 horas após a retirada do implante. A IATF foi realizada 54 horas após a retirada do implante. O diagnóstico de gestação foi realizado por ultra-sonografia 30 dias após a IATF. Houve interação entre os tratamentos e o PPP. No PPP1, a taxa de concepção foi maior no grupo eCG comparado ao BE (47,22% vs. 15,38%; P
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Evaluación de implantes de Norgestomet reutilizados en protocolos de sincronización del estro en vacas Brahman
'Universidad de Cordoba', 2013Co-Authors: Luis Uribe-velásquez, Adriana Correa-orozco, Lina Cuartas-betancurth, Diego Villamizar-ramirez, Santiago Ángel-boteroAbstract:RESUMEN Objetivo. Evaluar las concentraciones de progesterona, la manifestación de estro y las tasas de preñez en vacas Bos indicus sometidas a varios protocolos de sincronización del estro con un implante de Norgestomet usado previamente. Materiales y métodos. Sesenta vacas recibieron un implante auricular de Norgestomet reutilizado y fueron distribuidas en uno de cuatro protocolos: (1) benzoato de estradiol (BE) + progesterona (P4) + prostaglandina F2α (PG) (BE+P4+PG); (2) valerato de estradiol (VE) + Norgestomet (NG) (VE+NG); (3) el mismo protocolo BE+P4+PG, asociado con 400 UI de gonadotropina coriónica equina (eCG) (BE+P4+PG+eCG); (4) el mismo protocolo VE+NG, asociado con 400 UI de eCG (VE+NG+eCG). El implante fue removido el día 9, con inseminación artificial (IA) 12 horas después de la detección del estro. La preñez fue diagnosticada 45 días después de la IA. Las muestras de sangre fueron tomadas los días 0, 4 y 9 (después de colocar el implante) para el análisis de progesterona por RIA. Resultados. En el día 4, las concentraciones de progesterona fueron menores en vacas tratadas con BE+P4+PG (0.90 ± 0.73 ng/ml; p0.05). Conclusiones. Los implantes de Norgestomet reutilizados fueron eficaces para sincronizar el estro y alcanzar tasas de preñez adecuadas en vacas Brahman
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Evaluación de implantes de Norgestomet reutilizados en protocolos de sincronización del estro en vacas Brahman
Universidad de Cordoba, 2013Co-Authors: Luis Uribe-velásquez, Adriana Correa-orozco, Lina Cuartas-betancurth, Diego Villamizar-ramirez, Santiago Ángel-boteroAbstract:Objetivo. Evaluar las concentraciones de progesterona, la manifestación de estro y las tasas de preñez en vacas Bos indicus sometidas a varios protocolos de sincronización del estro con un implante de Norgestomet usado previamente. Materiales y métodos. Sesenta vacas recibieron un implante auricular de Norgestomet reutilizado y fueron distribuidas en uno de cuatro protocolos: (1) benzoato de estradiol (BE) + progesterona (P4) + prostaglandina F2α (PG) (BE+P4+PG); (2) valerato de estradiol (VE) + Norgestomet (NG) (VE+NG); (3) el mismo protocolo BE+P4+PG, asociado con 400 UI de gonadotropina coriónica equina (eCG) (BE+P4+PG+eCG); (4) el mismo protocolo VE+NG, asociado con 400 UI de eCG (VE+NG+eCG). El implante fue removido el día 9, con inseminación artificial (IA) 12 horas después de la detección del estro. La preñez fue diagnosticada 45 días después de la IA. Las muestras de sangre fueron tomadas los días 0, 4 y 9 (después de colocar el implante) para el análisis de progesterona por RIA. Resultados. En el día 4, las concentraciones de progesterona fueron menores en vacas tratadas con BE+P4+PG (0.90 ± 0.73 ng/ml; p
